We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App

Voice-Activated Sample Pre-Treatment Device Enables Hands-Free, Safer DNA Handling

By LabMedica International staff writers
Posted on 10 Feb 2023
Print article
Image: The small, voice-activated device extracts and pretreats bacterial DNA (Photo courtesy of ACS Sensors)
Image: The small, voice-activated device extracts and pretreats bacterial DNA (Photo courtesy of ACS Sensors)

Scientists using samples containing pathogens work with the smallest amounts possible in order to avoid accidental infection. In the case of highly contagious bacterial diseases, on-site sample analysis is suitable for rapid diagnoses. Additionally, scientists with visual or other physical impairments can find it difficult to operate complex instruments, particularly those designed for tiny volumes. Now, the same technology used by smart voice assistants could also make the laboratory a safer place for scientists and technicians handling infectious samples.

Hands-free devices that can be operated quickly using voice commands could make the laboratory safer for scientists and technicians. Researchers at Kyung Hee University (Yongin, South Korea) set out to combine a speech recognition app with a miniaturized extraction system to do just that. The researchers first built a microfluidic chip with multiple chambers linked together by six 3-way solenoid valves, which were operated by a micro-controller connected to a Bluetooth module. The palm-sized device weighed only 11 ounces and was powered by a portable battery or a 5V smartphone charger. Using existing speech recognition software, the team went on to customize a smartphone app to listen for specific voice commands.

The voice-activated system is simple to operate. As soon as the user says one of the operation commands out loud, the app wirelessly sends an initiation signal to the micro-controller. After receiving the signal, the micro-controller automatically begins a series of steps, including sample loading, washing and releasing the purified DNA into a collection chamber. Currently, the system requires the user to touch the smartphone to start the speech recognition software, although the entire operation could soon become completely hands-free with the addition of virtual assistant software.

The researchers conducted tests of the system in which the voice-controlled device extracted DNA from Salmonella Typhimurium, purifying a 10-µL sample with an efficiency of 70% in less than a minute. The system’s performance was lower as compared to a traditional DNA extraction kit, although its voice control, portability and quick automation lend it an advantage for convenient and safe bacterial DNA testing, according to the researchers.

Related Links:
Kyung Hee University

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
One Step HbA1c Measuring System
Complement 3 (C3) Test
GPP-100 C3 Kit
Gold Member
Xylazine Immunoassay Test
Xylazine ELISA

Print article


Molecular Diagnostics

view channel
Image: Prostate cancer cell image taken using a scanning electron microscope (Photo courtesy of LRI EM Unit)

New Discoveries of Prostate Cancer Evolution Pave Way for Genetic Test

Prostate cancer ranks as one of the most common cancers affecting men, and while it accounts for a significant number of male cancer fatalities, many men live with it rather than die from it.... Read more


view channel
Image: The Gazelle Hb Variant Test (Photo courtesy of Hemex Health)

First Affordable and Rapid Test for Beta Thalassemia Demonstrates 99% Diagnostic Accuracy

Hemoglobin disorders rank as some of the most prevalent monogenic diseases globally. Among various hemoglobin disorders, beta thalassemia, a hereditary blood disorder, affects about 1.5% of the world's... Read more


view channel
Image: The companies will develop genetic testing systems based on capillary electrophoresis sequencers (Photo courtesy of 123RF)

Sysmex and Hitachi Collaborate on Development of New Genetic Testing Systems

Sysmex Corporation (Kobe, Japan) and Hitachi High-Tech Corporation (Tokyo, Japan) have entered into a collaboration for the development of genetic testing systems using capillary electrophoresis sequencers... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.