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Image: The Ventana BenchMark Ultra autostainer is for cancer diagnostics with automation and the test menu include IHC, ISH, and FITC tests (Photo courtesy of Ventana Medical System)

Specific Biomarker Investigated for Triple-Negative Breast Cancer Diagnosis

Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression and comprises a heterogeneous group of breast cancers that exhibit distinct morphologic features and biological behavior. More...
30 Nov 2021
Image: The miRNeasy Serum/Plasma Kit: For purification of cell-free total RNA, including miRNA, from human plasma and serum (Photo courtesy of Qiagen)

Serum MicroRNA Panel Predict P-Tau/Aβ42 in CSF in Alzheimer's Disease

Amyloid β (Aβ) and tau pathologies are classic characteristic features of Alzheimer’s disease (AD), and they are widely used as diagnostic biomarkers. AD pathology is characterized by the accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the brain. More...
29 Nov 2021
Image: Olympus AI-based pathology diagnostic tool (Photo courtesy of Olympus)

AI-Based Pathology Diagnostic Tool for Gastric Cancer Achieves 100% Sensitivity in Trials

Olympus Life Science (Waltham, MA, USA) has announced the results of its ongoing joint research program to create an AI-based pathology diagnostic tool with the potential to streamline pathologists’ workloads. The diagnostic tool achieved 100% sensitivity and 50% or more specificity for all gastric biopsy pathology specimens analyzed. More...
29 Nov 2021
Image: Absence of nuclear immunohistochemical staining of MSH2 protein (A) and presence of MLH1 protein (B) in urothelial cell carcinoma of the urinary bladder of a patient carrying a germline MSH2 mutation. Observe the nuclear staining in stromal cells as an internal control (Photo courtesy of Radboud University Nijmegen Medical Centre)

Simple Urine Test Detects Urothelial Cancers in Lynch Syndrome Patients

Lynch Syndrome (LS) is an inherited genetic disorder that carries a high risk of cancer. LS is caused by mutations affecting MLH1, MSH2, MSH6 or PMS2 genes. More than one in 300 people have LS but most do not know it and that is equivalent to more than 2,300 new cases every year in the UK. More...
24 Nov 2021
Image: POC pathogen detection system (Photo courtesy of Fraunhofer IPM)

POC System that Requires Single DNA Molecule for Rapid Detection of Multidrug-Resistant Pathogens Unveiled at MEDICA 2021

A new compact device for detecting multidrug-resistant pathogens that performs all stages of the reaction automatically and provides a result within one hour using one single DNA molecule was unveiled at MEDICA 2021. More...
18 Nov 2021
Image: Men with Certain Pathogenic Variants Had a Higher Incidence of Prostate Cancer (Photo courtesy of UrologyAustin)

Men with Certain Pathogenic Variants Had a Higher Incidence of Prostate Cancer

Prostate cancer is one of the major causes of morbidity and mortality in men worldwide. The importance of germline genetic variation for identifying men at increased risk of prostate cancer to enable targeted screening and early detection has become increasingly recognized. More...
17 Nov 2021
Image: The limulus amebocyte lysate (LAL) assay measures endotoxin activity (Photo courtesy of HyCult Biotechnology)

Endotoxemia Genetic Profile Reveals an Association with Thromboembolism and Stroke

Microorganisms are part of the human body, and bacteria or their components often end up in the circulation. One such bacterial component is lipopolysaccharide (LPS), which is a toxin. High concentrations of LPS in the blood cause sepsis. Low LPS levels, known as endotoxemia, cause low-grade inflammation. More...
09 Nov 2021

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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