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Pathology

Image: According to a new study, a gene mutation may accelerate the loss of memory and thinking skills in people who are at risk for Alzheimer’s disease (Photo courtesy of iStock).

Alzheimer’s Disease Progression Predicted by Gene Mutation

Alzheimer's disease is the most common form of dementia in older adults. It is a degenerative condition, characterized by a steady loss of memory and a reduced ability to carry out daily activities. Today, an estimated five million people in the USA are living with the disease. More...
25 May 2017
Image: E. coli (shown here growing on an agar plate) is three-fold more common in advanced NAFLD patients than early stage patients, according to a recent study (Photo courtesy of the University of California San Diego School of Medicine / J. Craig Venter Institute).

Pathogens Help Diagnose Fatty Liver Disease

Nonalcoholic fatty liver disease is a condition characterized by a buildup of fat in the liver and the condition is often not detected until it is well advanced, and a definitive diagnosis requires an invasive biopsy of the liver. More...
25 May 2017
Image: Endometriosis in the peritoneal tissue (left) forming a scar. Under microscopy, it is composed of glands and surrounding stroma with chronic inflammation and fibrosis (Photo courtesy of Ie-Ming Shih).

Gene Sequencing Reveals Mutations in Endometriosis

Endometriosis occurs when tissue lining the uterus forms and grows outside of the organ, most often into the abdomen. The disease occurs in up to 10% of women before menopause and half of those with abdominal pain and infertility problems. More...
24 May 2017
Image: Researchers have devised a new microscopic tool to detect and analyze single melanoma cells that are more representative of the skin cancers developed by most patients (Photo courtesy of the University of Missouri).

Microscopy Innovation Developed to Diagnose Cancer

Researchers have developed a spectrophotometric technique for microscopic analysis of variations in single cancer cells, enabling more efficient diagnosis of melanomas, including metastasize forms. More...
23 May 2017
Image: Immunofluorescence staining showing extension of prostatic adenocarcinoma into the bladder wall in a castration resistant prostate (Photo courtesy of the Institute of Cancer Research).

Test Predicts Benefit of Targeted Cancer Treatments

There is an urgent need to develop biomarker strategies to a priori identify castration-resistant prostate cancer (CRPC) patients who will derive minimal benefit from androgen receptor (AR) targeting and offer them an alternative treatment paradigm. More...
17 May 2017
Image: New research suggests that there may be a link between blood sugar and glioma (Photo courtesy of MNT).

Glioma Risk Lower with Elevated Blood Sugar

While many cancers are more common among those with diabetes, cancerous brain tumors called gliomas are less common among those with elevated blood sugar and diabetes. More...
16 May 2017
Image: The enlarged, basophilic, smudgy viral inclusions typical of BK polyoma virus nephropathy are seen in the tubular epithelium in this renal transplant case (Photo courtesy of Brent Weedman).

BK Virus Biomarkers Determined by Urine Samples

Transplants are lifesaving treatments for patients with end-stage kidney disease but around 25% fail within five years, either because the body begins to reject the new organ, or because a viral infection has taken hold of the kidney. More...
11 May 2017


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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