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Histopathology of acute pancreatitis: necrosis of pancreatic parenchyma (lower left) with acute inflammation and fat necrosis (right and upper part of photograph) (Photo courtesy of Florida State University College of Medicine)

Heparin-Binding Protein Levels Dramatically Increase in Acute Pancreatitis

Heparin-binding protein (HBP), also known as CAP37 and azurocidin, is a glycoprotein stored in azurophilic granules and secretory vesicles in neutrophils that is released upon neutrophil activation early in the systemic inflammatory response. More...
25 Sep 2021
The SpectraMax Plus 384 Microplate Reader can run both standard spectrophotometer and microplate reader applications on the same instrument (Photo courtesy of Molecular Devices)

Urinary VEGFA and Renal Pathology Evaluated for IgA Nephropathy Patients

Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary glomerulonephritis and is the leading cause of end-stage renal disease (ESRD) in China. Renal biopsy remains the golden standard for diagnosing and monitoring IgA nephropathy (IgAN). More...
25 Sep 2021

Certest Offers Real-Time PCR Assays for Fast Detection of MDR Bacterial Infections

CerTest Biotec (Zaragoza, Spain; www.certest.es) has joined the fight against multidrug resistant strains (MDR) bacterial infections by developing real-time PCR assays for the fast detection of genes or punctual mutations that confer resistance to antibiotics from both Gram-positive and Gram-negative pathogens. More...
23 Sep 2021
Image: The BD FACSLyric Flow Cytometry System (Photo courtesy of BD Diagnostics)

Encephalitis After Immunotherapy Detected Early by Blood Test

Immunotherapy is very effective for many cancers, but the treatment can also cause autoimmune side effects. Encephalitis is one of the most serious and difficult-to-diagnose side effects of immunotherapy. More...
16 Sep 2021
Image: The Invitrogen Qubit 4 Fluorometer is designed to accurately measure DNA, RNA, and protein quantity (Photo courtesy of Thermo Fisher Scientific)

Blood Testing Distinguishes Benign Tumors from Precancerous Condition

The leading cause of mortality for patients with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the development of malignant peripheral nerve sheath tumor (MPNST), an aggressive soft tissue sarcoma. In the setting of NF1, this cancer type frequently arises from within its common and benign precursor, plexiform neurofibroma (PN). More...
15 Sep 2021
Image: The NanoQuant infinite M200 pro reader is an easy-to-use multimode plate reader family (Photo courtesy of Neotec Scientific Instrumentation)

CCN1 Analyzed as a Biomarker for Breast Cancer Detection

Breast cancer is the most frequent malignancy in women with 1.7 million new cases and over 500,000 deaths worldwide in 2016. Early detection of cancer is believed to be crucial in reducing cancer death. Despite recent progress in liquid biopsy technologies, early blood-based detection of breast cancer is still a challenge. More...
14 Sep 2021
Image: Schematic representation of cancer-related biomolecules such as cells, proteins, nucleic acids, miRNA and microvesicles circulating into the bloodstream, and collection of these biomarkers by liquid biopsy (Photo courtesy of University of Florence)

Liquid Biopsy Assay Evaluated for Early Detection of Gastric Cancer

Gastric cancer (GC) is the fourth most-commonly diagnosed cancer, and the third leading cause of cancer-associated mortality worldwide. Despite improvements in treatment modalities, the prognosis for advanced GC following curative resection remains poor. More...
08 Sep 2021

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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