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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
16 Aug 2021 - 26 Aug 2021
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Image: Immunohistochemical (IHC) analysis of the normal tissue from a healthy subject showed several Matrix Metalloproteinase-13 (MMP-13) positive cells (light brown staining indicated by the red arrow in panel a. Panel b is an IHC microphotograph for the cSCC tissue, and brown staining can be seen in most of tumor cells (Photo courtesy of Weifang People’s Hospital)

Diagnostic Biomarker MMP-13 Explored for Cutaneous Squamous Cell Carcinoma

Cutaneous basal cell carcinoma (cBCC) and cutaneous squamous cell carcinoma (cSCC) account for approximately 80% and 20% of non-melanoma skin cancer (NMSC), respectively Although the majority of cSCCs are successfully eradicated by surgical excision, a subset of cSCC possesses features associated with a higher likelihood of recurrence, metastasis, and death. More...
27 Jul 2021
Image: The HE4 EIA is an enzyme immunometric assay for the quantitative determination of human epididymis protein 4 (HE4) in human serum. HE4 is consistently expressed in patients with ovarian cancer, and it has demonstrated increased sensitivity and specificity over that of CA125 alone (Photo courtesy of Fujirebio)

Immunoassays Compared for Serum HE4 Estimation for Ovarian Cancer

Ovarian cancer is the sixth most common cancer in women and the leading cause of death from gynecological malignancy in the UK. Cancer antigen 125 (CA125) is the most widely used diagnostic biomarker for ovarian cancer; however it lacks the diagnostic accuracy to reliably detect ovarian cancer at an early stage. More...
26 Jul 2021
Image: Axiom Genome-Wide Population-Optimized Human Arrays are genotyping panels that offer the best genetic coverage of rare and common variants for genome-wide disease association studies (Photo courtesy of Thermo Fisher Scientific)

Preemies' Blood Type Tied to Risk for Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) and focal intestinal perforation (FIP) are two of the most common emergencies of the gastrointestinal tract in preterm infants with very low birth weight (VLBW). The etiology and pathogenesis of NEC and FIP remain poorly understood. More...
21 Jul 2021
Image: Telomerase reverse transcriptase (TERT) expression in non-lentiginous acral melanoma (NLAM) and non-acral cutaneous melanoma (NACM): (A) exhibiting 1+ TERT staining intensity and (B) The intensity of TERT expression and proportion of TERT-positive cells could also vary in cutaneous melanomas (Photo courtesy of MD Anderson Cancer Center)

Telomerase Reverse Transcriptase Protein Expression Evaluated for Melanomas

Telomeres are regions of repetitive nucleotide sequences located at the ends of chromosomes that play a key role in the maintenance of genomic integrity and stability in cells. In normal nonneoplastic somatic cells, telomeres progressively shorten with successive cell divisions. More...
19 Jul 2021
Image: Nanoanalysis of plasma volatile organic compounds used novel DNA-decorated carbon nanotube vapor sensors to noninvasively distinguish ovarian and pancreatic cancer from benign and control samples (Photo courtesy of the University of Pennsylvania)

Electronic Nose Sensor Accurately Detects Ovarian, Pancreatic Cancers

Ovarian cancer is a cancer that forms in or on an ovary. It results in abnormal cells that have the ability to invade or spread to other parts of the body. When this process begins, there may be no or only vague symptoms. Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. More...
15 Jul 2021
Image: The Super Sensitive 1-STEP Polymer HRP IHC detection kit (Photo courtesy of BioGenix)

Protein Biomarker Helps Diagnose Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC), characterized by dense desmoplastic stroma laid down by pancreatic stellate cells (PSC), has no reliable diagnostic biomarkers for timely detection. More...
14 Jul 2021
Image: Histology of acute pancreatitis. Microscopically, the fat necrosis consists of steatocytes (adipocytes) that have lost their nuclei and whose cytoplasm has a granular pink appearance as seen on the right. Some hemorrhage is seen at the left in this case of acute pancreatitis (Photo courtesy of Texas A&M University)

Biomarkers Diagnose and Predict Acute Pancreatitis

Acute pancreatitis (AP) is an inflammatory reaction caused by the activated pancreatic enzymes in the pancreas, which leads to subsequent pancreatic autodigestion, edema, hemorrhage, necrosis, and even distal organ dysfunction. More...
08 Jul 2021

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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