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Pathology

Image: The HISCL-5000 is a fully automated immunoassay analyzer with a throughput of 200 tests per hour. The incubation time for each parameter is 17 minute and allows each laboratory to achieve maximum efficiency and productivity (Photo courtesy of Sysmex Corporation).

Automated Immunoassay Systems Evaluated for KL‐6 Antigen Quantification

Interstitial lung disease (ILD) is a group of diseases characterized by various forms of pulmonary interstitial inflammation and fibrosis, which are usually chronic, progressive, and fatal, causing death 2‐5 years after diagnosis in most patients. More...
20 Nov 2019
Image: Histopathology of prostate cancer: crystalloids (bright eosinophilic rhomboid to prismatic structures, seen in ~40% cancer) and amorphous eosinophilic secretions (Photo courtesy the American Urological Association).

High Levels Of Blood Hormones Raise Prostate Cancer Risk

Men with higher levels of 'free' testosterone and a growth hormone in their blood are more likely to be diagnosed with prostate cancer. Other factors such as older age, ethnicity and a family history of the disease are already known to increase a man's risk of developing prostate cancer. More...
11 Nov 2019
Image: A scanning electron micrograph (SEM) of prostate cancer cells (Photo courtesy of Sloan Kettering Institute).

Prostate Cancer Methylation Levels Linked to Epigenetic Profiles

Prostate cancer is cancer that occurs in the prostate, a small walnut-shaped gland in men that produces the seminal fluid that nourishes and transports sperm. Prostate cancer is one of the most common types of cancer in men. More...
07 Nov 2019
Image: The HiSeq X Series incorporates patterned flow cell technology to generate an exceptional level of throughput for whole-genome sequencing (Photo courtesy of Illumina).

Metastatic Tumor Profiles Lead to Potential Treatment Targets

Metastatic cancer is a major cause of death and is associated with poor treatment efficacy. A better understanding of the characteristics of late-stage cancer is required to help adapt personalized treatments, reduce overtreatment and improve outcomes. More...
05 Nov 2019
Image: Diagram of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations (Photo courtesy of Biocept Inc).

Full Analytical Data Validated for Target Selector ctDNA Assays

Tumor tissue has traditionally been required for both cancer diagnosis and molecular biomarker testing. All too often, acquired tissue is exhausted during the initial diagnosis, leaving insufficient tissue for subsequent biomarker testing. More...
05 Nov 2019
Image: Blood tests can sample circulating DNA cast off by solid tumors, providing information about the tumor and its likely response to treatment without the need for an invasive tumor biopsy (Photo courtesy of Rachel June Wong).

Post-Treatment Colon Cancer Recurrence Identified by ctDNA Detection

By analyzing circulating tumor DNA (ctDNA) samples after treatment, it may be possible to identify stage III colon cancer patients who are at increased risk of relapse and disease progression. More...
30 Oct 2019
Image: A microscope image of thyroid cancer cells, specifically papillary thyroid carcinoma, or PTC (Photo courtesy of Wendong Yu/Baylor College of Medicine).

Metabolic Classification of Thyroid Nodules Uses MS Imaging

Fine-needle aspiration (FNA) biopsy is a well-established technique for diagnosis of suspicious thyroid lesions. However, histologic discrimination between malignant and benign thyroid nodules from FNA can be challenging. More...
26 Oct 2019


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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