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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Clinical Chem.

Image: The Sysmex XE-2100D automated hematology analyzer (Photo courtesy of Bimedis)

Complete Blood Count Parameters Associated With Pancreatic Beta-Cell Function

The pathophysiology of type 2 diabetes mellitus (T2DM) involves insulin resistance (IR) and progressive deterioration of beta-cell function (BCF). Estimation of IR and BCF is essential for screening subjects at a high risk of T2DM and making treatment plans in clinical practice. More...
19 May 2022
Image: The analysis pipeline used to investigate associations between blood metabolites, later life brain imaging measures, and genetic risk for Alzheimer’s disease (Photo courtesy of University College London)

Lipid Measurements Show Potential as Alzheimer’s Disease Biomarkers

Brain changes accompanying ageing are varied and can include pathologies that lead to cognitive impairment, the commonest of which is Alzheimer’s disease (AD). Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. More...
17 May 2022
Image: The new BS-600M chemistry analyzer provides a complete package to help labs grow (Photo courtesy of Mindray)

Mindray Launches High Throughput BS-600M Chemistry Analyzer with Industry-Leading Small Footprint

Mindray (Shenzhen, China) has launched the new BS-600M, a powerful yet efficient chemistry analyzer designed to empower medium-volume laboratories with increased productivity, efficiency and reliability. More...
16 May 2022
Image: ROC curve AUC and levels of Proenkephalin A 119–159 (PENK) 48 hours after liver transplantation in the need-renal replacement therapy groups (Photo courtesy of University of Sao Paulo)

Biomarker Proenkephalin Investigated in Diagnosis of Acute Kidney Injury

Liver transplantation (LT) is the only treatment available for patients with end-stage liver disease, such as liver cancer or acute and subacute liver failure. Among the various types of postoperative organ damage, acute kidney injury (AKI) is particularly prevalent, developing in 5% to 20% of patients undergoing major non-cardiac surgery. More...
12 May 2022
Image: a) Schematic of Tear Collection using Schirmer strip before being analyzed by LC-MS/MS and validated by ELISA. b) Functional classification of 301 mapped proteins in tear samples using PANTHER classification system (Photograph courtesy of Namida Lab)

Tear-Based Method Detects Breast Cancer

With advances in screening techniques, and adjustment of recommended screening guidelines, mortality rates due to breast cancer continue to decline. Despite the estimated waning in mortality rates, breast cancer still remains the highest cancer diagnosis of women globally. More...
11 May 2022
Image: TripleTOF 6600+ System optimized for large-scale quantitative mass spectrometry and offers sensitive and robust quantitation using dedicated low flow source technology (Photo courtesy of Sciex)

Proteins Linked to COVID-19-Associated Inflammatory Syndromes

COVID-19 associated acute respiratory distress syndrome (COVID-19 ARDS) is one of the major manifestations of the severe cases, characterized by hypoxemic respiratory failure with bilateral lung infiltrate, as well as multi-organ dysfunction and extensive microthrombus formation. More...
10 May 2022
Image: The Phadia 250 Immunoassay Analyzer, in addition to allergy testing, allows measurement of autoantibodies of more than 20 autoimmune related diseases using the EliA product line (Photo courtesy of Thermo Fisher Scientific)

Biochemical Abnormalities Among Celiac Disease Patients Referred for Antibody Testing

Celiac disease (CD) is a chronic disease occurring in all age groups and affecting approximately 1% of the population, although many cases of CD remain undiagnosed. This condition is caused by an abnormal immune response in genetically susceptible individuals triggered by the ingestion of gluten proteins from wheat, rye and barley. More...
09 May 2022


The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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