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Clinical Chemistry

Image: The Brahms Kryptor automated immunoassay platform (Photo courtesy of Thermo Fisher Scientific).

Immunoassay Biomarkers Evaluated for Preeclampsia Diagnosis

Preeclampsia is one of the leading hypertensive disorders in pregnant women worldwide and it is estimated to cause more than 60,000 deaths per year. Preeclampsia is induced by placental and maternal vascular dysfunction, which affects both maternal and neonatal health. More...
17 Aug 2017
Image: Various blood collection tubes for use in the clinical laboratory (Photo courtesy of Labs USA).

Trends in Metabolites Predict Mortality for Hospitalized Patients

Patients who are hospitalized for an extensive period are at risk for adverse outcomes and are likely to have a high mortality rate than those who have shorter stays. More...
17 Aug 2017
Image: The compact PATHFAST Immunoanalyzer used for the presepsin point-of-care assay (Photo courtesy of LSI Medience Corporation).

Increased Probability of Sepsis Mortality Associated with SOFA Score

Sepsis-related organ failure assessment score, also known as sequential organ failure assessment score (SOFA score), is used to track a person's status during the stay in an intensive care unit (ICU) to determine the extent of a person's organ function or rate of failure. More...
17 Aug 2017
Image: The Wescor Sweat Check Analyzer Model 3120 for total electrolyte analysis of sweat samples (Photo courtesy of ELITech Group).

Biomarkers Lead to Better Prognosis for CF Patients

Cystic fibrosis is a life-shortening and multi-organ autosomal recessive disease characterized by pancreatic insufficiency and recurrent lung infections that contribute to growth failure and progressive respiratory dysfunction. More...
16 Aug 2017
Image: Researchers have discovered a new biomarker that is associated with a rare metabolic disorder may facilitate better diagnosis and identification of new drugs for clinical trials (Photo courtesy of iStock).

Biomarker May Help Monitor MPS Disease Progression

Researchers have identified spermine as a potential biomarker associated with neuropathic forms of mucopolysaccharidoses (MPS), a family of rare metabolic disorders. Assaying for abnormally high levels of spermine may facilitate better diagnosis, monitoring, and identification of more effective drugs. More...
15 Aug 2017
Image: The cobas e 411immunoassay analyzer (Photo courtesy of Roche Diagnostics).

Performance of Immunosuppressant Drug Assay Kits Analyzed

Cyclosporine (CsA) and tacrolimus (TAC) are immunosuppressant drugs that are often used to treat autoimmune diseases and as transplantation therapy and therefore, their concentrations need to be monitored carefully. More...
08 Aug 2017
Image: Sensing device:  Simple characterizing target gas concentrations of human exhaled breath will lead to diagnose of the disease as well as physical condition (Photo courtesy of The Korea Advanced Institute of Science and Technology).

Innovative Nanosensor Developed for Disease Diagnosis

In human breath, diverse components are found including water vapor, hydrogen, acetone, toluene, ammonia, hydrogen sulfide, and carbon monoxide, which are more excessively exhaled from patients. Some of these components are closely related to diseases such as asthma, lung cancer, type 1 diabetes mellitus, and halitosis. More...
03 Aug 2017


The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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