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Clinical Chemistry

Image: Schematic diagram of the microfluidic chip platform (D.Adnan, N. R.deBarros, L. S.Santovito, et al., Advanced Science (2026). DOI: 10.1002/advs.202508934)

Patient-Derived Tumor-on-a-Chip Recapitulates Pancreatic Microenvironment for Drug Testing

A new tumor-on-a-chip system recreates pancreatic tumors and shows stromal targeting improves chemotherapy response. More...
06 May 2026
Image: The dSAA method partitions a patient’s cerebrospinal fluid into nanoliter-scale compartments and digitally counts the number of TDP-43 protein “seeds” present under a microscope (image credit: Shutterstock)

Ultrasensitive Test Detects Key Biomarker of Frontotemporal Dementia Subtype

An ultrasensitive CSF assay enables noninvasive FTLD-TDP identification and severity monitoring More...
06 May 2026
Image: New findings show that routine blood tests performed several years before pregnancy are associated with later risk of hypertension and pre-eclampsia (photo credit: Adobe Stock)

Routine Blood Tests Years Before Pregnancy Could Identify Preeclampsia Risk

New findings show routine blood tests years before pregnancy flag later risk of gestational hypertension and pre‑eclampsia. More...
04 May 2026
Image: The blood test uses an immune-profiling method to detect germ cell tumors, the most common form of testicular cancer (photo credit: Adobe Stock)

Blood Test Detects Testicular Cancer Missed by Standard Markers

A new immune-profiling blood test detects germ cell tumors, even when standard markers are negative, improving diagnosis. More...
29 Apr 2026
Image: Researchers identified a set of scalable, blood-based biomarkers associated with PTSD using common clinical laboratory tests (photo courtesy of Adobe Stock)

Routine Blood Tests Identify Biomarkers Linked to PTSD

Researchers identify 16 PTSD-linked biomarkers in common blood tests, enabling systemic monitoring during routine care. More...
28 Apr 2026
Image: Study results show blood protein levels change markedly in childhood and adolescence, with sex differences increasing with age (photo credit: Adobe Stock)

Proteomic Data Underscore Need for Age-Specific Pediatric Reference Ranges

New data show pediatric serum proteins shift with age and sex, supporting more specific reference intervals. More...
25 Apr 2026
Image: An elevated neutrophil-to-lymphocyte ratio (NLR), a rato easily obtained from a routine blood count, was associated with both short- and long-term Alzheimer’s risk (photo credit: 123RF)

Routine Blood Count Ratio Linked to Future Alzheimer’s and Dementia Risk

New data link elevated neutrophil-to-lymphocyte ratio on CBC to higher future Alzheimer’s and dementia risk. More...
24 Apr 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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