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Clinical Chemistry

Image: Plasma pTau217 testing can predict future amyloid accumulation and cognitive decline in cognitively healthy older adults (photo courtesy of Shutterstock)

Blood Test Predicts Alzheimer Disease Risk Before Imaging Changes and Symptoms

Plasma pTau217 testing predicts future amyloid buildup and cognitive decline before PET, enabling early risk stratification. More...
15 Apr 2026
Image: ApoB is a blood test that counts the total number of harmful particles in circulation, providing a more complete assessment of risk (photo courtesy of Adobe Stock)

Study Finds ApoB Testing More Effective Than LDL for Guiding Lipid Therapy

New findings show apolipoprotein B (ApoB) testing better guides lipid therapy than LDL/non-HDL. More...
14 Apr 2026
Image: Overview of the dual-mode xVFA optical sensor platform for multiplexed cardiac biomarker detection in point-of-care settings (Han, GR., Eryilmaz, M., Goncharov, A. et al. Light Sci Appl 15, 190 (2026). doi.org/10.1038/s41377-026-02275-9)

AI-Enabled POC Test Quantifies Multiple Cardiac Biomarkers

An AI-enabled portable test quantifies cTnI, CK-MB, and NT-proBNP in 23 minutes, improving point-of-care MI and HF triage. More...
10 Apr 2026
Image: The cobas c 703 and cobas ISE neo increase testing capacity and automation to enhance lab workflows and patient care (photo courtesy of Roche)

Next Generation Automated Analyzers Increase Throughput for Clinical Chemistry and Electrolyte Testing

Roche has received FDA 510(k) clearance for cobas c703 and cobas ISE neo, next-generation units that enhance laboratory efficiency and capability. More...
08 Apr 2026
Image: The findings could pave the way for a blood test to detect risk of cognitive decline years before dementia is typically diagnosed (photo courtesy of Adobe Stock)

Blood Metabolite Test Detects Early Cognitive Decline

An AI approach using six blood metabolites detects early cognitive decline with high accuracy, guiding risk stratification. More...
06 Apr 2026
Image: Workflow of ProtAIDe-Dx on GNPC (An, L., Pichet Binette, A., Hristovska, I. et al. Nature Medicine (2026). https://doi.org/10.1038/s41591-026-04303-y)

AI-Based Blood Test Diagnose Multiple Brain Disorders from Blood Sample

An AI approach analyzes proteins in a single blood sample to detect several brain diseases simultaneously.  More...
02 Apr 2026
Image: The new MultiQ-IT prototype can cool, trap, filter, and redirect over a billion ions simultaneously, dramatically improving dynamic range and signal-to-noise (Photo courtesy of Lori Chertoff/The Rockefeller University)

Breakthrough Mass Spectrometry Design Could Enable Ultra-Low Abundance Detection

A new mass spectrometry spectoprototype can cool, trap, filter, and redirect over a billion ions simultaneously. More...
31 Mar 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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