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Clinical Chemistry

Image: The QSight Triple Quad 400 Series Liquid Chromatography Mass Spectrometry (Photo courtesy of PerkinElmer).

Endogenous Testosterone Levels Associated with Risk of Diabetes

High plasma levels of endogenous total and circulating free testosterone are associated with a two- to sevenfold increased risk for developing type 2 diabetes among young, healthy women without comorbidities. More...
02 Jun 2020
Image: The C-reactive protein (CRP) test was one of the biomarkers evaluated in children with community-acquired pneumonia (Photo courtesy of Healsens Digital Preventive Care).

Biomarkers Evaluated in Children with Community-Acquired Pneumonia

Community acquired pneumonia (CAP) is one of the most common conditions treated by pediatricians, yet predicting disease severity and prognosis is often difficult at the initial presentation. More...
01 Jun 2020
Image: The Element 2 High Resolution, Sector-Field, Inductively Coupled Plasma Mass Spectrophotometer (HR-ICP-MS) (Photo courtesy of Thermo Fisher Scientific).

Elevated Metal Ion Level Detects Defective Hip Arthroplasty Implants

Total hip replacement (THR) has proven to be a highly effective treatment of degenerative joint disease. Hip replacement implants can be made of different metallic alloys according to their specific properties and the related clinical need. More...
26 May 2020
Image: The UniCel DxI 800 Access Immunoassay System (Photo courtesy of Beckman Coulter).

Soluble Transferrin Receptor Investigated in Iron Deficiency Anemia

Anemia is a global public health problem and approximately 30% of the world's population suffered from anemia, with children and pregnant women being the most affected. Microcytic hypochromic anemia is a common type of anemia, and iron deficiency anemia (IDA) is the most common manifestation of this anemia. More...
25 May 2020
Image: Histopathological micrograph of pancreatic adenocarcinoma arising in the pancreas head region (Photo courtesy of KGH).

Biomarker Data Improves Risk Prediction for Pancreatic Cancer

Pancreatic cancer risk prediction models based on clinical factors may be refined and improved by bringing in other types of data, including germline genetic risk variant and blood-based biomarker data. More...
07 May 2020
Image: The Clusterin Human ELISA kit (Photo courtesy of Invitrogen).

Blood Biomarkers Help Diagnose Parkinson's Disease

The identification of circulating biomarkers that closely correlate with Parkinson’s disease (PD) has failed several times in the past. A conventional pipeline for biomarker discovery usually contemplates the collection of clinical samples, such as blood, and their analysis by mass spectrometry. More...
05 May 2020
Image: The Vertex 70 Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectrophotometer (Photo courtesy of the University of Guelph).

Salivary Molecular Spectroscopy Used to Monitor Diabetes

Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia which results from insufficient secretion and/or reduced insulin action in peripheral tissues. Frequent monitoring of diabetes is essential for improved glucose control and to delay clinical complications related with diabetes. More...
28 Apr 2020


The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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