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Technology

Image: The Celltac G fully-automatic hematology analyzer with 33 parameters (Photo courtesy of Nihon Kohden)

Leukocyte Differential on Hematology Analyzer Compared and Evaluated

A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells). More...
21 Jun 2021
Image: Examples of negative and positive Chagas Stat-Pak RDT results. From left to right, negative, weakly positive, and strongly positive Stat-Pak results are shown (Photo courtesy of Yves Jackson)

Rapid Diagnostic Tests Evaluated for Chronic Chagas Disease Patients

Chagas is a disease caused by the parasite Trypanosoma cruzi, and is one of the most important public health concerns affecting the population of Latin America. This disease presents an acute phase that generally goes undiagnosed and a chronic phase with cardiac manifests principally, is diagnosed through serological tests that are generally not available. More...
15 Jun 2021
BIOHIT  Healthcare OY
Image: The CoaguChek Pro II Coagulation Meter and CoaguChek PT Test Strips (Photo courtesy of Roche Diagnostics)

Point-of-Care Testing Evaluated for Early Coagulopathy Diagnosis

Hemorrhage and coagulopathy are particularly relevant complications and are often connected to injuries, surgical interventions, serious diseases, anticoagulant medication or pregnancy/delivery. Acute bleeding requires fast and targeted therapy and therefore, knowledge of the patient's potential to form a clot is crucial. More...
09 Jun 2021
Image: Computer-generated Mycobacterium tuberculosis bacteria, Ziehl-Neelsen stain. The reagents used are carbol fuchsin, acid alcohol, and methylene blue counterstain Acid-fast bacilli stain red and the background is blue (Photo courtesy of  microbiologyinpictures)

Serum Based Antigen Test Detects Childhood Tuberculosis

Approximately one million children develop tuberculosis (TB) and 205,000 die of TB-related causes each year. Eighty percent of these deaths occur in children < 5 years old, with the majority (96%) of deaths occurring among children who did not receive treatment, where missed diagnoses are likely responsible for undertreatment. More...
01 Jun 2021
Image: Results of the Recombinase Polymerase Amplification-Lateral Flow (RPA-LF) assay for cutaneous leishmaniasis (Photo courtesy of University of Texas Medical Branch)

RPA-LF Assay Evaluated for Cutaneous Leishmaniasis in Colombia

Cutaneous leishmaniasis (CL) is a recognized public health challenge in the Americas, with an average of 55,000 cases per year between 2001 and 2018 in 17 countries of the region. Most cases (79.4%) have been acquired in and continue to occur in rural areas. More...
17 May 2021
Image: Standard hematoxylin-eosin sections are unaffected by processing and imaging by clearing histology with multiphoton microscopy (CHiMP). Portions of the same core biopsy were submitted directly to standard processing (A) or processed by CHiMP and subsequently embedded in paraffin, sectioned, and stained (B), showing equivalent coloration and morphology (Photo courtesy of Yale School of Medicine)

Rapid, Direct-to-Digital Prostate Biopsy Pathology Evaluated

Increasing adoption of digital pathology promises marked improvements in reproducibility, efficiency, and accuracy of tissue-based diagnostics by facilitating routine remote expert consultation and enabling computerized image analysis for clinical use. More...
13 May 2021
Image: The Capillarys 3 TERA is an automated analyzer based on capillary zone electrophoresis and UV detection for the quantitative analysis of Hba1c, proteins (serum and urine), immunotyping (serum and urine), and carbohydrate deficient transferrin (Photo courtesy of Sebia)

Gel and Capillary Electrophoresis Compared for Human Proteins

The electrophoresis of serum proteins remains a laboratory cornerstone for the diagnosis and monitoring of patients with plasma cell disorders, such as monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, and AL amyloidosis. More...
12 May 2021


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