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Technology

Image: Illustration demonstrating painless and biodegradable microneedles on a paper patch (Photo courtesy of University of Tokyo)

Paper-Based Microneedle Skin Patch for Continuous Glucose Monitoring

A microneedle skin patch for the continuous monitoring of an individual’s glucose level was designed to be a painless and disposable screening and diagnostic test for diabetes patients, as well as those with pre-diabetes. More...
23 Sep 2020
Image: The Aedes aegypti mosquito can spread various tropical diseases including dengue, zika, and chikungunya, which have similar symptoms (Photo courtesy of Gwangju Institute of Science and Technology)

A Paper-Based Nucleic Acid Testing Device for Rapid Diagnosis of Mosquito-Borne Viral Diseases

An all-in-one nucleic acid testing device loaded into a paper chip forms the basis for a simple, rapid diagnostic test for a range of mosquito-borne viral diseases. More...
22 Sep 2020
Image: The QX200 droplet digital polymerase chain reaction (ddPCR) instrument (Photo courtesy of Bio-Rad).

Click Chip’ Detects Early-Stage Liver Cancer Biomarkers in Extracellular Vesicles

 Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related deaths worldwide. The poor prognosis of HCC can be attributed to the fact that diagnosis is often made at a late stage in disease development. More...
21 Sep 2020
Image: Upconverting nanoparticles: With the combination of NIR-excitation (980 nanometers) and detection at a lower wavelength, the autofluorescence from biological samples is totally eliminated, and the particles are detectable through tissue sections and even in whole blood (Photo courtesy of Kaivogen Oy)

Novel Rapid Lateral Flow Assay Measures Ovarian Cancer Biomarker CA125

A radically modified lateral flow immunoassay was able to detect the ovarian cancer biomarker glycosylated CA125 in serum samples and rapidly differentiate epithelial ovarian cancer from benign endometriosis and healthy controls. More...
21 Sep 2020
Image: The Mindray BC-2800 Fully Automatic Hematology Analyzer with 19 Parameters for CBC /Blood Cell Test for Hospital Use (Photo courtesy of Mindray).

Quantitative Agglutination Determined on Automatic Hematology Analyzer

The currently available agglutination identification methods are slide methods and test tube methods. Based on the distribution, uniformity and comprehensive changes of non-aggregated cells and agglutinating cells in the liquid, the agglutination degree and strength can be determined by the naked eye. More...
16 Sep 2020
Image: Illustration depicting the marriage of DNA nanotechnology and bioelectronics (Photo courtesy of EatFishDesign)

Biosensing Platform Diagnoses Diseases Through Single Molecule Detection

A new diagnostic approach employs a DNA origami biosensor platform coupled with a nanopore read-out that enables individual biomarker detection. More...
15 Sep 2020
Image: A test tube contains saliva that can be tested for the heart attack biomarker cardiac troponin (Photo courtesy of karenfoleyphoto).

Saliva Test Fast Tracks Heart Attack Diagnosis

 Heart attacks need urgent diagnosis, followed by treatment to restore blood flow to blocked arteries. Diagnosis is based on symptoms (such as chest pain), an electrocardiogram (ECG) and a blood test for cardiac troponin, a protein released into the blood when the heart muscle is injured. More...
07 Sep 2020


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