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Portable Diagnostic Tool Uses Bioluminescence to Detect Viruses at POC

AI Method Predicts Overall Survival Rate of Prostate Cancer Patients

Paper-Based Diagnostic Device Detects Infectious Diseases In 10 Minutes

Real-Time Genome Sequencing Detects Dangerous Superbug Causing Hospital Infections

Simple Paper Test Offers Early Cancer Diagnosis

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POC Diagnostic Platform Performs Immune Analysis Using One Drop of Fingertip Blood

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Cutting‑Edge Non‑Invasive System Revolutionizes Point-of-Care Hospital Diagnostics

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New AI Tool Accurately Predicts Spread of Infectious Disease

AI Oncology Tool Uses Medical Imaging and Genetic Information to Support Clinical Decisions

AI-Assisted Non-DNA Based Test Identifies Viral Infections in Minutes

Image: Structure of the herpes virus, nanopore module, and its waveform (Hashida et al., PNAS Nexus (2025), doi.org/10.1093/pnasnexus/pgaf161)

A non-DNA based test can identify viral infections in patients in minutes.
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11 Jun 2025

AI Tool Identifies Gene Combinations Causing Complex Illnesses

11 Jun 2025

Genomic Test Guides Chemotherapy Decisions in Older Breast Cancer Population

11 Jun 2025

Portable Device Detects Rare Genetic Mutations from Single Drop of Blood

11 Jun 2025

ctDNA Blood Tests Improve Lung Cancer Diagnosis

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Image: The AI model compares the epigenetic data of unknown tumors to the fingerprints of over 8,000 reference tumors (Photo courtesy of Philipp Euskirchen/Charité)

AI Model Detects More Than 170 Cancer Types

Diagnosing brain tumors can be especially difficult when the tumor is located in a region where biopsies pose high risks. Read more
10 Jun 2025 | Pathology

Image: New research has linked skin barrier dysfunction to pediatric eosinophilic esophagitis (Photo courtesy of 123RF)

Simple Skin Test Could Revolutionize Diagnosis of Pediatric Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a chronic, food allergen-driven condition marked by inflammation and damage to the esophageal lining. Read more
10 Jun 2025 | Clinical Chem.

Image: The LIAISON PLEX® Gram-Positive Blood Culture Assay runs on the on the LIAISON PLEX instrument (Photo courtesy of Diasorin)

Blood Culture Assay Enhances Diagnostic Stewardship Through Targeted Panel Selection

Each year, around 250,000 individuals in the US are diagnosed with bloodstream infections (BSIs). Sepsis caused by these infections carries a mortality rate ranging from 16% to 40%, and any delay in administering appropriate treatment further heightens patient risk. Read more
10 Jun 2025 | Microbiology

Image: The platform can detect bacterial STIs, urinary tract infections and viral infections in just five minutes (Photo courtesy of Linear Diagnostics)

Low-Cost Near-Patient Diagnostic Platform Rapidly Diagnoses STIs

Every day, over one million sexually transmitted infections (STIs) are acquired worldwide. Rapid diagnosis and appropriate antibiotic treatment are crucial to control their spread. Read more
10 Jun 2025 | Molecular Diagnostics

Image: The new technology combines a rapid hemoglobin test with a smartphone app (Photo courtesy of 123RF)

Smartphone-Based Rapid Hemoglobin Test Accurately Detects Colorectal Cancer

Despite the availability of colorectal cancer screening programs, participation remains low, especially for fecal immunochemical tests (FIT), a non-invasive method to detect hidden blood in the stool. Read more
09 Jun 2025 | Pathology

Image: Non-coding RNAs CBR3-AS1 and PCA3 can be utilized as therapeutic targets and prognostic biomarkers in gastric cancer (Photo courtesy of Adobe Stock)

Promising Molecular Markers Support Earlier Diagnosis of Gastric Cancer

Late detection continues to make gastric cancer one of the leading causes of cancer-related deaths globally. Read more
09 Jun 2025 | Molecular Diagnostics

Image: A microRNA-based risk score for Type 1 Diabetes (Photo courtesy of Western Sydney University)

World’s First AI-Powered Tool to Transform Type 1 Diabetes Diagnosis and Treatment

For years, testing for Type 1 Diabetes (T1D) has relied on symptoms and biomarkers that typically become evident only at the disease’s onset, making early detection difficult. Read more
09 Jun 2025 | Molecular Diagnostics

Image: A blood-based test aims to address gaps in population-level early cancer detection (Photo courtesy of Harbinger Health)

Blood-Based MCED Test Enables Early-Stage Detection for Multiple Cancer Types

Around 84,000 new cancer cases in the United States each year are thought to arise from obesity, and over the past two decades, the rate of obesity-related cancers has climbed markedly. Read more
09 Jun 2025 | Molecular Diagnostics

Image: The LEX VELO system aims to redefine point-of-care testing (Photo courtesy of LEX Diagnostics)

POC System Delivers Lab-Quality PCR Results Directly from Swab Sample in Minutes

Medical and laboratory staff in primary care settings are multi-skilled and routinely multitask to deliver care with the speed and convenience expected of modern medicine. Read more
09 Jun 2025 | Molecular Diagnostics

Image: A ctDNA blood test detected 79% of colorectal cancers in a screening study (Photo courtesy of Shutterstock)

Blood-Based ctDNA Test Demonstrates Acceptable Accuracy for Colorectal Cancer Detection

Colorectal cancer (CRC) remains the second leading cause of cancer-related deaths globally, with over 1. Read more
09 Jun 2025 | Molecular Diagnostics

Image: The tip optofluidic immunoassay platform enables rapid, multiplexed antibody profiling using only 1 μL of fingertip blood (Photo courtesy of hLife, DOI:10.1016/j.hlife.2025.04.005)

POC Diagnostic Platform Performs Immune Analysis Using One Drop of Fingertip Blood

As new COVID-19 variants continue to emerge and individuals accumulate complex histories of vaccination and infection, there is an urgent need for diagnostic tools that can quickly and accurately assess immune protection. Read more
06 Jun 2025 | Immunology

Image: The collaboration aims to speed up the adoption of ultrasensitive immunoassays incorporating single-molecule counting technology (Photo courtesy of Fujirebio)

Fujirebio Collaborates with Stanford Medicine to Advance Infectious Disease Research

Fujirebio (Tokyo, Japan) has entered into a collaboration with Stanford Medicine (Palo Alto, CA, USA) to accelerate the adoption of ultrasensitive immunoassays that incorporate single-molecule counting technology developed by Fujirebio’s wholly-owned subsidiary, Fluxus, Inc. Read more
06 Jun 2025 | Industry

Image: Cutting-edge hospital genomics initiative takes on dangerous superbug (Photo courtesy of 123RF)

Real-Time Genome Sequencing Detects Dangerous Superbug Causing Hospital Infections

Superbug infections caused by Staphylococcus aureus, or ‘golden staph’, are notoriously difficult to treat and claim over one million lives globally each year. Read more
06 Jun 2025 | Microbiology

Image: Cancers can be detected in the bloodstream prior to clinical signs or symptoms (Photo courtesy of 123RF)

MCED Tests Detect Cancers in Bloodstream Three Years Prior To Diagnosis

Detecting cancer before symptoms emerge remains a major challenge in oncology. Now, a new study reveals that tumor-derived genetic material can be found in the bloodstream as early as three years before clinical diagnosis. Read more
06 Jun 2025 | Molecular Diagnostics

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Clinical Chemistry

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Image: A new diagnostic tool shines a powerful new light into the viral darkness (Photo courtesy of Adobe Stock)

Portable Diagnostic Tool Uses Bioluminescence to Detect Viruses at POC

Point-of-care diagnostics have become crucial tools in many households, enabling individuals to measure blood sugar, conduct pregnancy tests, and even perform their own COVID-19 assays. These diagnostics... Read more

Image: The POC device rapidly predicts neonatal respiratory disease at birth in the NICU (Photo courtesy of SIME Diagnostics)

AI-Powered Lung Maturity Test Identifies Newborns at Higher Risk of Respiratory Distress

Each year, approximately 300,000 babies in the United States are born between 32 and 36 weeks' gestation, according to national health data. This group is at an elevated risk for respiratory distress,... Read more

Image: The GlycoLocate platform uses multi-omics and advanced computational biology algorithms to diagnose early-stage cancers (Photo courtesy of AOA Dx)

AI-Powered Blood Test Accurately Detects Ovarian Cancer

Ovarian cancer ranks as the fifth leading cause of cancer-related deaths in women, largely due to late-stage diagnoses. Although over 90% of women exhibit symptoms in Stage I, only 20% are diagnosed in... Read more

Image: The researchers detected genomic alterations from plasma cfDNA (Photo courtesy of 123RF)

Automated Decentralized cfDNA NGS Assay Identifies Alterations in Advanced Solid Tumors

Current circulating cell-free DNA (cfDNA) assays are typically centralized, requiring specialized handling and transportation of samples. Introducing a flexible, decentralized sequencing system at the... Read more

Molecular Diagnostics

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Image: NHS is the first in the world to roll out a revolutionary blood test for cancer patients (Photo courtesy of Adobe Stock)

Revolutionary Blood Test Aims to Fast-Track Lung Cancer Patients for Targeted Therapy

Delays in diagnosing and treating lung and breast cancer can significantly affect patient survival, especially when access to targeted therapies hinges on time-consuming tissue biopsies.... Read more

Image: The new diagnostic based on analysis of urine samples could also be designed to reveal whether a tumor has metastasized (Photo courtesy of MIT)

Simple Paper Test Offers Early Cancer Diagnosis

Diagnosing cancer at an early stage remains a significant clinical challenge, particularly in resource-limited settings where access to advanced testing equipment is scarce. Conventional detection methods... Read more

Image: The precision oncology test identifies patients most at risk of undergoing severe toxicity from treatment with 5FU/capecitabine (Photo courtesy of 123RF)

Precision Oncology Test Predicts Patient Toxicity Before Beginning Chemotherapy

5-fluorouracil (5FU) and capecitabine have been cornerstone chemotherapeutic agents for over four decades, effectively treating a variety of cancers. However, 5FU/capecitabine can cause varying degrees... Read more

Image: Pathlight is a tumor-informed, multi-cancer MRD platform with its first indication in breast cancer (Photo courtesy of SAGA Diagnostics)

Blood-Based Multi-Cancer Test Sets New Standard for Ultra-Sensitive and Early MRD Detection

Detecting minimal residual disease (MRD) and early recurrence in cancer patients remains a major clinical challenge, particularly for those with early-stage breast cancer. Despite curative-intent treatment,... Read more

Hematology

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Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Image: The FINDER multifunctional testing platform can run multiple types of tests and deliver rapid results for near-patient use (Photo courtesy of Baebies)

First Point-of-Care Heparin Monitoring Test Provides Results in Under 15 Minutes

Heparin dosing requires careful management to avoid both bleeding and clotting complications. In high-risk situations like extracorporeal membrane oxygenation (ECMO), mortality rates can reach about 50%,... Read more

Image: The 3-parameter CCRS model was devised specifically for patients diagnosed with clonal cytopenia (Photo courtesy of 123RF)

New Scoring System Predicts Risk of Developing Cancer from Common Blood Disorder

Clonal cytopenia of undetermined significance (CCUS) is a blood disorder commonly found in older adults, characterized by mutations in blood cells and a low blood count, but without any obvious cause or... Read more

Image: The technology has the unique ability to detect challenging RhD variants that are typically excluded by other commercial tests (Photo courtesy of BillionToOne)

Non-Invasive Prenatal Test for Fetal RhD Status Demonstrates 100% Accuracy

In the United States, approximately 15% of pregnant individuals are RhD-negative. However, in about 40% of these cases, the fetus is also RhD-negative, making the administration of RhoGAM unnecessary.... Read more

Immunology

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Image: Switching to an experimental drug after liquid biopsy detection of breast cancer recurrence can improve outcomes (Photo courtesy of Shutterstock)

Treatment Switching Guided by Liquid Biopsy Blood Tests Improves Outcomes for Breast Cancer Patients

Standard treatment for patients with advanced estrogen receptor (ER)-positive, HER2-negative breast cancer, a subtype driven by estrogen receptors that fuel tumor growth, often involves aromatase inhibitors,... Read more

Image: Custom hardware and software for the real-time detection of immune cell biophysical signatures in NICU (Photo courtesy of Pediatric Research, DOI:10.1038/s41390-025-03952-y)

First-Of-Its-Kind Device Profiles Newborns' Immune Function Using Single Blood Drop

Premature infants are highly susceptible to severe and life-threatening conditions, such as sepsis and necrotizing enterocolitis (NEC). Newborn sepsis, which is a bloodstream infection occurring in the... Read more

Image: The cancer stem cell test can accurately choose more effective treatments (Photo courtesy of University of Cincinnati)

Stem Cell Test Predicts Treatment Outcome for Patients with Platinum-Resistant Ovarian Cancer

Epithelial ovarian cancer frequently responds to chemotherapy initially, but eventually, the tumor develops resistance to the therapy, leading to regrowth. This resistance is partially due to the activation... Read more

Machine Learning-Enabled Blood Test Predicts Immunotherapy Response in Lymphoma Patients

Chimeric antigen receptor (CAR) T-cell therapy has emerged as one of the most promising recent developments in the treatment of blood cancers. However, over half of non-Hodgkin lymphoma (NHL) patients... Read more

Microbiology

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Diagnostic Test Accurately Detects Colorectal Cancer by Identifying Microbial Signature in Gut Bacteria

Colorectal cancer remains one of the deadliest and most common forms of cancer worldwide, with only 40% of cases diagnosed before metastasis. Current screening methods, like colonoscopy, are invasive and... Read more

Image: PowerBlade is a portable device that uses a drop of blood and an automated sequence of steps to efficiently detect sepsis (Photo courtesy of NRC)

Rapid Bedside Test Predicts Sepsis with Over 90% Accuracy

Sepsis is a severe response to an infection that causes the immune system to attack the body's own organs and tissues, potentially leading to organ failure and death if not addressed promptly.... Read more

Image: The new prototype blood test for infectious diseases is designed to be delivered and analyzed at the POC (Photo courtesy of Abertay University)

New Blood Test Detects Up to Five Infectious Diseases at POC

Researchers have developed a prototype flow-through assay capable of detecting up to five different infections, with results that can be quickly analyzed and transmitted via a specialized smartphone app.... Read more

Image: The molecular stool test could improve detection of tuberculosis in adults with HIV (Photo courtesy of ISGlobal/George William Kasule et al, 2025)

Molecular Stool Test Shows Potential for Diagnosing TB in Adults with HIV

Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, led to 1.25 million deaths in 2023, with 13% of those occurring in people living with HIV. The current primary diagnostic method for... Read more

Pathology

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Image: Microscopy image of invasive breast cancer cells degrading their underlying extracellular matrix (Photo courtesy of University of Turku)

Visualization Tool Illuminates Breast Cancer Cell Migration to Suggest New Treatment Avenues

Patients with breast cancer who progress from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) face a significantly worse prognosis, as metastatic disease remains incurable.... Read more

Image: A new at-home self-collection device aims to reduce the screening gap for cervical cancer (Photo courtesy of CU School of Medicine)

New At-Home Cervical Cancer Screening Device to Increase Accessibility for Patients

Cervical cancer is typically linked to certain types of human papillomavirus (HPV), which is passed through sexual contact. While many people are infected with HPV, only a small percentage will develop... Read more

Image: Mimix Reference Standards are cell-line derived to maintain genomic complexity and mimic patient material across molecular diagnostics workflows (Photo courtesy of Revvity)

New Cancer Testing Standards to Improve Diagnostic Accuracy for Oncology Labs

Accurate diagnosis, including the identification of genomic markers, is essential for determining the most effective cancer treatments for patients. To ensure this, laboratories require reliable reference... Read more

Image: An algorithm within the Check4 platform interprets data from the cartridge and sends test results to users by text or email (Photo courtesy of IdentifySensors)

Digital Diagnostic Platform Uses Electronic Technology for Rapid Disease Detection

Traditional diagnostic methods often fall short in providing rapid, accurate detection of infectious diseases, leading to delays in treatment and increased transmission. Now, a groundbreaking digital diagnostics... Read more

Technology

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Image: The machine learning-based method delivers near-perfect survival estimates for PAC patients (Photo courtesy of Shutterstock)

AI Method Predicts Overall Survival Rate of Prostate Cancer Patients

Prostate adenocarcinoma (PAC) accounts for 99% of prostate cancer diagnoses and is the second most common cancer in men globally after skin cancer. With more than 3.3 million men in the United States diagnosed... Read more

Image: The second-generation sampler currently under development (Photo courtesy of Breathe BioMedical)

Breath Test to Enable Early Detection of Breast Cancer

Mammograms often fail to detect breast cancer in women with dense breast tissue, missing up to 60% of cases due to reduced image clarity. Breath analytics has the potential to allow for timely detection... Read more

Image: Concept of biosensor integrated into hygiene pads enabling direct semi-quantitative analysis of biomarkers in unprocessed menstruation blood (Photo courtesy of Dosnon, L et al. DOI: 10.1002/advs.202505170)

First Ever Technology Recognizes Disease Biomarkers Directly in Menstrual Blood in Sanitary Towels

Over 1.8 billion people menstruate worldwide, yet menstrual blood has been largely overlooked in medical practice. This blood contains hundreds of proteins, many of which correlate with their concentration... Read more

Image: Scanning electron microscopy images showing 3D micro-printed Limacon-shaped whispering-gallery-mode microcavities with different amounts of deformation (Photo courtesy of A. Ping Zhang/PolyU)

Tiny Microlaser Sensors with Supercharged Biosensing Ability to Enable Early Disease Diagnosis

Optical whispering-gallery-mode microlaser sensors function by trapping light within tiny microcavities. When target molecules bind to the cavity, they induce subtle changes in the laser’s frequency, allowing... Read more

Industry

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Image: The LEX system brings together high speed and high sensitivity in a PCR molecular system to redefine POC diagnostics (Photo courtesy of LEX Diagnostics)

QuidelOrtho to Acquire MDx Company LEX Diagnostics

QuidelOrtho Corporation (San Diego, CA, USA) has announced a refocusing of its molecular diagnostics strategy which now includes acquiring LEX Diagnostics (Cambridgeshire, UK) and discontinuing development... Read more

Image: The new partnerships enhance QIAGEN’s capabilities to support pharma partner clinical trials using QIAcuity digital PCR (Photo courtesy of QIAGEN)

QIAGEN Enters into New Strategic Partnerships for Expanding MRD Testing Portfolio in Oncology

Minimal residual disease (MRD) testing offers a highly sensitive way to monitor treatment response, identify patients at risk of relapse before symptoms appear and inform decisions on therapy usage.... Read more

Danaher and AstraZeneca Partner on Next Generation AI-Powered Diagnostics

Danaher Corporation (Washington, D.C., USA) has entered into a partnership with AstraZeneca (Cambridge, UK to develop and commercialize novel diagnostic tools and tests intended to help clinicians... Read more

Image: EUROMEDLAB is the largest international gathering of laboratory professionals and scientists in Europe (Photo courtesy of IFCC)

EuroMedLab 2025 Showcases Latest Technologies and Innovations in Laboratory Medicine

The 26th IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine (EuroMedLab 2025), hosted by the Royal Belgian Society of Laboratory Medicine (RBSLM, Verviers, Belgium), in collaboration... Read more

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