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Wearable Tool Created for Monitoring Diabetes

Thermo Clinical Analyzer Provides Range of Laboratory Tests

Next-Generation Hematology Analyzer Introduced

PCR Test for Vaginal Pathogens Approved for Use

Combined Molecular Test Distinguishes Benign Pancreatic Lesions

Assays Evaluated for Early Diagnosis of Leptospirosis

Simple Test Improves Treatment for Colon Cancer Patients

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30 Jul 2017 - 01 Aug 2017

AACC 2017 – 68th Annual Meeting of American Association for Clinical Chemistry

02 Sep 2017 - 06 Sep 2017

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10 Sep 2017 - 13 Sep 2017

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Elastomeric Biomaterial Guards against Incisional Hernia

Coffee Consumption Associated with Reduced Mortality

Male Partner Age Affects IVF Delivery Rates

Hospital Discharge Program Improves Patient Experience

New Technique Monitors Nerves During Surgery

BiotechDaily

Nanoparticle Treatment Cures Bacterial Infection in Model

Stem Cells Used to Generate Functional Arterial Endothelial Cells

RSV Non-Structural Protein Interferes with Host Immune Response

Structural Analysis Explains Action of New Gene Editing Tool

3D-Printed Heart Valve Models Mimic Physiology

$Image: Researchers found that patients with Parkinson\'s were roughly four times more likely to have had a history of melanoma than those without Parkinson\'s (Photo courtesy of iStock).$

Parkinson’s Disease Patients at Higher Risk for Melanoma

Study finds that people with Parkinson’s disease have a much higher risk of the skin cancer melanoma, and vice versa. Physicians treating patients with one disease should be vigilant for signs of the other in order to achieve early diagnosis and treatment, and patients should be educated about the risk of developing the other illness.
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24 Jul 2017

Nanolock Sensor Detects Cancer Driver Mutation

24 Jul 2017

Blood Protein Test May Provide Early Cancer Detection

24 Jul 2017

Alzheimer's Disease Biomarker Assay Heading for IVD Status

24 Jul 2017

Rapid Diagnostic Test for RSV Evaluated

20 Jul 2017

Portable Device Finds Sepsis Infection Markers

20 Jul 2017

Industry Spotlight

Siemens to Acquire Blood Gas Subsidiary of Alere

Siemens Healthineers (Erlangen, Germany), the separately managed healthcare business of Siemens AG, has entered into a definitive agreement to acquire Epocal Inc. Read more
24 Jul 2017

Quidel to Acquire Alere Triage Assets

Quidel Corporation (San Diego, CA, USA), a provider of rapid diagnostic testing solutions, cellular-based virology assays and molecular diagnostic systems, has entered into definitive agreements to acquire the Triage MeterPro cardiovascular (CV) and toxicology assets (“Triage business”) and the B-type Naturietic Peptide (BNP) assay business run on Beckman Coulter analyzers (“BNP business”) from Alere Inc. Read more
24 Jul 2017

Global Clinical Lab Services Market to Reach USD 327 Billion by 2025

The global clinical laboratory services market is expected to reach USD 327 billion by 2025, driven by the improvement and implementation of informatics and automated data management solutions to perform seamless operations. Read more
17 Jul 2017

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In Other News

Image: A 3D model of a chromosome, using the Hi-C visualization technique (Photo courtesy of Babraham Institute).

Mapping Genes Could Improve Cancer Diagnosis

Large-scale changes to the structure of the genome are often seen in cancer cells and scientists have found a way to detect these changes, which could enhance cancer diagnosis and aid the use of targeted treatments. Read more
20 Jul 2017 | Molecular Diagnostics

Image: A new diagnostic blood test has been developed for detection of De Vivo disease (Photo courtesy of Fotalia).

Blood Test Developed to Detect Rare Neurological Disease

A diagnostic blood test has been developed for a rare but treatable condition called De Vivo disease. Read more
19 Jul 2017 | Molecular Diagnostics

Image: Recent studies suggest S-adenosylhomocysteine (SAH), and not Hcy, plays a role in cardiovascular disease (Photo courtesy of Shutterstock).

Novel Biomarker Identifies Early Clinical CV Disease

Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide, and the economic, social, and costs associated with treating CAD are very high. Read more
19 Jul 2017 | Clinical Chemistry

Image: The Advia Centaur XP immunoassay analyzer (Photo courtesy of Siemens Healthcare).

Relationship of Serum Cortisol and Serum Sodium Analyzed

Hyponatremia is the most common electrolyte disorder encountered by the clinical biochemist, and is associated with a significant mortality and hypernatremia is also a risk factor for mortality in critically ill patients. Read more
19 Jul 2017 | Clinical Chemistry

Image: A histopathology of a skin biopsy from a patient with amyloidosis. Protein clumps are in red (Photo courtesy of Professor Michael Polydefkis).

Nerve Biomarkers Found for Amyloid Polyneuropathy

A modified skin biopsy that hastens the earlier diagnosis of an inherited and progressively fatal nerve disease has been described that seems to offer a clearer view of the disorder's severity and progression. Read more
19 Jul 2017 | Pathology

Image: A new study shows important groups of bacteria are found less frequently in the gut of patients with heart failure, and the gut flora is not as diverse as in healthy individuals (Photo courtesy of Medical Xpress).

Heart Failure Associated with Depleted Intestinal Microbiota

It has long been known that heart failure and gut health are linked. The gut has a worse blood supply in instances of heart failure; the intestinal wall is thicker and more permeable, whereby bacteria and bacterial components may find their way into the blood. Read more
18 Jul 2017 | Molecular Diagnostics

Image: The 96.96 Dynamic Array IFC for Gene Expression, which enables 9,216 reactions using 96 samples and assay (Photo courtesy of Fluidigm).

Ultra-Early Inflammatory Biomarker Identified for TBI

Traumatic brain injury (TBI) is set to become the leading cause of neurological disability across all age groups. Read more
18 Jul 2017 | Molecular Diagnostics

Image: A scanning electron micrograph (SEM) of ovarian cancer cells (Photo courtesy of SPL).

MALDI-TOF-MS Analysis Identifies Ovarian Cancer Patterns

Ovarian cancer (OC) is one of the leading causes of death among all gynecological malignancies and as there are no early specific symptoms, OC is diagnosed in advanced clinical stages in more than 70% cases when, despite appropriate treatment, five-year survival rate drops to 30%. Read more
18 Jul 2017 | Clinical Chemistry

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Clinical Chemistry

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Image: In a review of studies on opioid genetics, researchers pinpointed 10 genes that show the highest potential of refining the way opioids are prescribed and that healthcare providers should focus on implementing clinically (Photo courtesy of Getty Images).

Opioid-Related Deaths Possibly Prevented By Gene Testing

More than 17,500 Americans died in 2015 from prescription opioid overdoses, which are more than quadruple the amount of people who died from this cause in 1999, but it is not just abuse of these medications... Read more

Image: The wearable diagnostic biosensor that can detect three interconnected, diabetes-related compounds, cortisol, glucose and interleukin-6, in perspired sweat for up to a week without loss of signal integrity (Photo courtesy of the University of Texas at Dallas).

Wearable Tool Created for Monitoring Diabetes

A wearable diagnostic biosensor has been developed that can detect three interconnected compounds, cortisol, glucose and interleukin-6, in perspired sweat for up to a week without loss of signal integrity.... Read more

Image: An operator stands at the control screen of the Cascadion clinical analyzer (Photo courtesy of Thermo Fisher Scientific).

Thermo Clinical Analyzer Provides Range of Laboratory Tests

A new mass spectrometry-based clinical analyzer has been introduced marking a potentially significant development in mass spectrometry evolution as a clinical technology. The analyzer brings together the... Read more

Amine Biomarkers Identify Risk of Alzheimer's Disease

The identification of novel biomarkers associated with Alzheimer's disease (AD) could provide key biological insights and permit targeted preclinical prevention. Circulating metabolites associated with... Read more

Molecular Diagnostics

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Image: Myoblast fusion. This graphic depicts normal myoblast (early muscle cells with a single nucleus) fusing together to form myocytes (multinucleated muscle cells) during myogenesis. In Carey-Fineman-Ziter syndrome this cascade is disrupted because of a defect in the membrane protein myomaker (MYMK) required for cell-cell fusion (Photo courtesy of Darryl Leja, NHGRI).

Genetic Mutations Causing CFZ Syndrome Identified

Researchers have identified gene mutations that cause, via a defect in myoblasts fusion, the rare inherited muscle disorder Carey-Fineman-Ziter Syndrome (CFZS), and have thereby also uncovered a mechanism... Read more

Image: A space-filling model of substance P (Photo courtesy of Wikimedia Commons).

Tear Substance Indicates Possible Nerve Damage in Diabetes Patients

Measurement of levels of substance P peptide in tears has been proposed as a method for determining possible nerve damage in individuals suffering from diabetes. Substance P is a neuropeptide composed... Read more

Image: A histopathology of urothelial carcinoma of the urinary bladder (Photo courtesy of Wikimedia Commons).

Urine Test Predicts Bladder Cancer Recurrence

A test that detects a specific enzyme in the urine is able to predict the likelihood of recurrence of disease in patients that have been treated for bladder cancer. Urothelial bladder cancer (UBC) is... Read more

Image: A light microscopy of an egg of Amphimerus sp. observed in a fecal specimen from Ecuador, almost indistinguishable from some other liver fluke eggs (Photo courtesy of Universidad Central del Ecuador).

Assay Detects Fish Trematode DNA in Human Stools

Amphimeriasis is a fish-borne disease caused by the liver fluke Amphimerus spp. that has recently been reported as endemic in the tropical Pacific side of Ecuador with a high prevalence in humans and domestic... Read more

Hematology

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Image: Clinical scientists analyzed the platelet counts of 249 patients with thalassemia, which were compared with the international reference method (IRM) for platelet counting in patients with thalassemia (Photo courtesy of Mahidol University).

Platelet Counts Compared for Thalassemia Patients

Platelet count is the component of complete blood count that is used to diagnose quantitative defect in platelets. Accuracy of platelet count is essential for determining bleeding risk in patients and... Read more

Image: A new test to aid in the detection of several leukemias and lymphomas has been approved by the FDA (Photio courtesy of Shutterstock).

FDA Approves New Diagnostic Tool for Leukemias and Lymphomas

A test for use with flow cytometry to aid in the detection of several leukemias and lymphomas, including chronic leukemia, acute leukemia, non-Hodgkin lymphoma, myeloma, myelodysplastic syndrome (MDS)... Read more

Image: The Sekisui CP3000 automated coagulation system seamlessly integrates with Abbott’s suite of informatics solutions (Photo courtesy of Abbott).

Fully Automated Coagulation System Launched

Coagulation tests measure the blood’s ability to clot and clotting disorders may be a sign of liver disease, thrombophilia (excessive clotting), or hemophilia (inability to clot normally).... Read more

Next-Generation Hematology Analyzer Introduced

Hematology is a medical specialty dedicated to studying the physiology of blood, and the cause, diagnosis, treatment, and prevention of diseases related to blood. In diagnostics testing, hematology tests... Read more

Immunology

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CE-Marked Immunoassay Rapidly Detects Infection Biomarkers

CE mark approval has been given for a point-of-care (POC) test for rapid detection of infection in patients on peritoneal dialysis (PD), enabling early diagnosis and treatment critical for preventing ... Read more

Image: The ImmunoDOT is a proprietary dotblot method reporting a semi-quantitative IgM titer for leptospirosis (Photo courtesy of GenBio).

Assays Evaluated for Early Diagnosis of Leptospirosis

Leptospirosis is a potentially life-threatening but curable zoonosis whose prognosis depends on accurate and timely diagnosis and because of its non-specific clinical presentation, laboratory testing is... Read more

Image: Toxoplasma gondii, the protozoan responsible for toxoplasmosis in humans (Photo courtesy of Science Life).

Toxoplasmosis POC Test Compared to Conventional Testing

Toxoplasmosis, a disease caused by the parasite Toxoplasma gondii, presents a major health burden in both the developed and developing world. Untreated congenital toxoplasmosis causes damage to the eyes... Read more

Image: Benign pancreatic mucinous cystic neoplasm (Photo courtesy of Wikipedia).

Combined Molecular Test Distinguishes Benign Pancreatic Lesions

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. Serous cystic neoplasms... Read more

Microbiology

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FDA Approves Fourth-Generation Blood Test

The US Food and Drug Administration (FDA) has approved a next-gen assay for latent tuberculosis (TB) infection that combines breakthrough CD4/CD8 design for comprehensive immune response detection with... Read more

Image: Cytomegalovirus. According to a new study, HIV-positive women with cytomegalovirus (CMV) in their urine at the time of labor and delivery are over five times likelier to transmit HIV than HIV-positive women without CMV (Photo courtesy of the CDC).

Women with HIV Frequently Pass CMV to Infant

Cytomegalovirus (CMV) can impair fetal growth, and babies born with the virus can have damage to the brain, liver, lung and spleen, as well as hearing loss. People who are otherwise healthy usually... Read more

Image: Salmonella typhi, the bacteria responsible for typhoid fever in humans (Photo courtesy of Getty Images).

Immunoassay Developed for Acute Typhoid Fever

Salmonelloses are a group of potentially fatal bacteremias caused by different serovars of Salmonella enterica. Typhoid fever (TF) caused by the human-specific serovar S. typhi, is a global health problem,... Read more

$Image: A new study found Charlie Sheen\'s HIV disclosure corresponded with millions of online search queries for HIV prevention and testing (Photo courtesy of OraSure Technologies).$

HIV Testing Peaks with Charlie Sheen Disclosure

A new study has found that record levels of HIV testing corresponded with celebrity actor Charlie Sheen's public disclosure of his being HIV-positive on a popular television program. On November 17,... Read more

Pathology

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Image: A scientist adjusting the versatile light-sheet microscope that can provide surgeons with real-time pathology data to guide cancer-removal surgeries and can also non-destructively examine tumor biopsies in 3D (Photo courtesy of Mark Stone/University of Washington).

Novel Microscope Scans Tumors and Examines Biopsies

Current pathology techniques involve processing and staining tissue samples, embedding them in wax blocks, slicing them thinly, mounting them on slides, staining them, and then viewing these two-dimensional... Read more

Image: A new study shows that so-called “liquid biopsies” - blood tests that detect circulating tumor DNA (ctDNA) - may not only sound an early alert that a treatment’s effect is diminishing, but may also help explain why and sometimes offer clues about what to do next (Photo courtesy of Massachusetts General Hospital).

Liquid Biopsy Blood Tests Detect CtDNA

The so-called “liquid biopsies” blood tests that detect circulating tumor DNA (ctDNA), may not only sound an early alert that a treatment’s effect is diminishing, but may also help explain why, and sometimes... Read more

Image: A health professional takes blood from a patient for the carcinoembryonic antigen (CEA) test (Photo courtesy of Mayo Clinic).

Simple Test Improves Treatment for Colon Cancer Patients

Colorectal cancer is the fourth most common cancer in the USA and the second deadliest. There are four primary stages of colon cancer. Generally, with stage 2, the cancer has not spread to nearby lymph... Read more

HPV Testing Leads to Earlier Detection of Pre-Cancer

Human papilloma virus (HPV) is a virus that can cause cervical, vaginal, penile and anal cancers. More than 520,000 cases of cervical cancer are diagnosed worldwide each year, causing around 266,000 deaths.... Read more

Lab Tech.

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Mass Spectrometry Detection for the Masses

Researchers are developing a plasma-based technology to enable generalized use of mass spectrometry (MS) with new instruments that can analyze a much broader range of molecular species than current technology... Read more

Miniature Technology May Improve Disease Detection

Researchers have developed an improved microcontact printing technology to create an optimal disease diagnostic device of bioreceptor arrays for multiplexed microfluidic assays. Since efficiency of... Read more

Image: An artist’s rendition of microparticles flowing through a channel and passing through electric fields, where they are detected electronically and barcode-scanned (Photo courtesy of Ella Marushchenko and Alexander Tokarev, Ella Maru Studios).

Lab-on-a-Chip Nanotechnology Tracks Multiple Markers

Research engineers have invented a technology for nanoelectronic barcoding of microparticles that could be used in wearable or hand-held devices to analyze body fluids, such as sweat or blood, for various... Read more

Image: The web-based Xplore system will allow for enhanced sharing of pathology and tissue images (Photo courtesy of Philips Healthcare).

Data Management System Integrates Complex Image Data

A web-based data management system that enables researchers to integrate data from multiple sources including digital pathology and tissue imaging and share information over the Internet is now available.... Read more

Industry News

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Image: The global hematology analyzer market is expected to surpass USD 2 billion by 2024 (Photo courtesy of Shutterstock).

Global Hematology Analyzer Market to Surpass USD 2 Billion by 2024

The global hematology analyzer market is expected to surpass USD 2 billion, driven by the introduction of new and innovative products & methods, with sales of 6-part differential analyzers to register... Read more

$Image: Brazil\'s IVD market is one of the largest, driven by increasing interest in molecular testing technologies, prenatal screening, and POC glucose testing (Photo courtesy of iStock).$

Brazilian IVD Market Fueled by Growing Demand

Brazil's in vitro diagnostic (IVD) market is one of the largest, driven by increasing interest in molecular testing technologies, prenatal screening, and point-of-care (POC) glucose testing.... Read more

Alliance Formed to Digitalize Medicine and Healthcare

The Universitätsklinikum Erlangen, Siemens Healthineers (Erlangen, Germany), the Friedrich-Alexander-Universität-Erlangen-Nürnberg (FAU), the Fraunhofer Institute for Integrated Circuits (IIS), and Medical... Read more

Image: PerkinElmer has entered into a definitive agreement to acquire EUROIMMUN Medical Laboratory Diagnostics (Photo courtesy of iStock).

PerkinElmer to Acquire EUROIMMUN

PerkinElmer, Inc. (Waltham, MA, USA), a provider of products, services and solutions for the diagnostics, research, environmental, industrial and laboratory services markets, has entered into a definitive... Read more

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