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BioMedomics Launches COVID-19 IgM-IgG Rapid Test for Novel Coronavirus

Israeli Scientists to Announce Development of Coronavirus Vaccine

Seegene Launches KFDA-Approved COVID-19 Assay

Israeli Researchers Introduce Pooling Method for COVID-19 Testing of Over 60 Patients Simultaneously

Abbott Launches Molecular Test for Novel Coronavirus (COVID-19)

Promega Custom Manufacturing Capabilities Aid Rapid Development of New Coronavirus Test from Co-Diagnostics

Bio-Rad Launches SARS CoV-2 Standard for Coronavirus (COVID-19) Testing

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Events

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ATTENTION: Due to the CORONAVIRUS EPIDEMIC, certain events are being rescheduled for a later date or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

13 May 2020 - 15 May 2020

FOCUS 2020– National Meeting (UK) of the Association for Clinical Biochemistry & Laboratory Medicine (ACB).

17 May 2020 - 21 May 2020

ASRI 2020 – 40th Annual Meeting of the American Society for Reproductive Immunology.

19 May 2020 - 22 May 2020

Hospitalar 2020.

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Total Wrist Replacement Device Treats Painful Arthritis

Agfa Offers Chest+ Software for Gridless Bedside Imaging Free to Support Healthcare’s COVID-19 Battle

GSK Collaborates with Vir Biotechnology to Find Coronavirus Solutions

XBiotech and BioBridge Jointly Developing COVID-19 Treatment Based on Natural Antibodies from Recovered Patients

AI Algorithms for Analyzing Chest X-ray/CT Scan Aid in Treatment of COVID-19 Infected Patients

Rapid, Portable, Point-of-Care COVID-19 Test Receives USD 13 Million Funding from BARDA

New Coronavirus (COVID-19) Antibody Test Can Help Determine Past COVID Infection

NEXTGENPCR Endpoint Thermocycler Decreases PCR Amplification Time for SARS-CoV-2 to Eight Minutes

BIOTECON Expedites Launch of Viral RNA Extraction Kit for Detecting COVID-19

Thermo Fisher Launches New AcroMetrix Coronavirus 2019 (COVID-19) RNA Control

Fluxergy Submits FDA EUA Request for One-Hour COVID-19 POC Test

ThermoGenesis Develops Blood Test to Detect COVID-19 in Minutes

Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples

More COVID-19 News

Potential Microbial Markers Identified for Cervical Pre-Cancer Progression

Image: Photomicrograph of a vaginal epithelial clue cell coated with Gardnerella vaginalis (Photo courtesy of Universidad Autónoma de Zacatecas).

Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections. However, only a small percentage of high-risk (HR) HPV infections progress to cervical pre-cancer and cancer. The role of the cervicovaginal microbiome (CVM) in the natural history of HR-HPV has been investigated. Read more
08 Apr 2020

Complete Blood Count Predicts Asymptomatic Preterm Birth

08 Apr 2020

Early Tumor Detection by Analysis of Circulating Free DNA Methylation Patterns

08 Apr 2020

C-Reactive Protein Predicts Neurological Outcomes of Subarachnoid Hemorrhage Patients

07 Apr 2020

sTNFR2 Revealed as a Novel Diagnostic Biomarker for Acute ATL

07 Apr 2020

Ultra-Fast Cycling for Multiplexed Cellular Fluorescence Imaging

07 Apr 2020

Industry Spotlight

Global Blood Glucose Monitoring Devices Market to Reach USD 13 Billion by 2023

The global blood glucose monitoring devices (BGMDs) market was valued at nearly USD 8 billion in 2018 and is projected to grow at a fast-paced CAGR of approximately 11% to reach USD 13 billion by 2023, driven by the phenomenal sales growth of new revolutionary continuous glucose monitoring systems (CGMs). Read more
16 Mar 2020

Global ELISA Kits Market to Surpass USD 418.5 Billion by 2025

The global ELISA (Enzyme-Linked Immunosorbent Assay) Kits market is projected to grow at a CAGR of 3. Read more
09 Mar 2020

Thermo Fisher Scientific to Acquire QIAGEN N.V.

Thermo Fisher Scientific Inc. (Waltham, MA, USA) has announced that it plans to acquire QIAGEN N.V. (Venlo, Netherlands), a provider of molecular diagnostics and sample preparation technologies. Read more
05 Mar 2020

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In Other News

Image: The Cue Health Monitoring System (Photo courtesy of Cue Health Inc.)

Rapid, Portable, Point-of-Care COVID-19 Test Receives USD 13 Million Funding from BARDA

Cue Health Inc. (San Diego, CA, USA), a healthcare technology company, has been awarded a USD 13 million contract to accelerate the development, validation and FDA clearance of a portable, molecular diagnostic test capable of detecting SARS-CoV-2, the virus that causes COVID-19, in less than 25 minutes using a simple nasal swab. Read more
07 Apr 2020 | COVID-19

Image: The AcroMetrix Coronavirus 2019 (COVID-19) RNA Control (Photo courtesy of Thermo Fisher Scientific Inc.)

Thermo Fisher Launches New AcroMetrix Coronavirus 2019 (COVID-19) RNA Control

Thermo Fisher Scientific Inc. (Waltham, MA, USA) has launched the AcroMetrix Coronavirus 2019 (COVID-19) RNA Control, its latest quality control product to monitor and validate COVID-19 molecular diagnostic tests. Read more
07 Apr 2020 | COVID-19

New Coronavirus (COVID-19) Antibody Test Can Help Determine Past COVID Infection

Eurofins Scientific’s (Luxembourg) US clinical diagnostics network is offering blood-based antibody testing for Coronavirus SARS-CoV-2 that can identify people who were exposed, may have developed some level of immunity to COVID-19 but potentially had mild to no symptoms. Read more
07 Apr 2020 | COVID-19

Image: The Fluxergy Analyzer (Photo courtesy of Fluxergy LLC)

Fluxergy Submits FDA EUA Request for One-Hour COVID-19 POC Test

Fluxergy LLC (Irvine, CA, USA), a research and medical diagnostic test company, has submitted an Emergency Use Authorization (EUA) request to the U. Read more
06 Apr 2020 | COVID-19

Image: The NEXTGENPCR thermocycler (Photo courtesy of Molecular Biology Systems, B.V.)

NEXTGENPCR Endpoint Thermocycler Decreases PCR Amplification Time for SARS-CoV-2 to Eight Minutes

Molecular Biology Systems, B.V. (Goes, The Netherlands), a biotechnology company, has developed a method using its NEXTGENPCR endpoint thermocycler and consumables that decreases PCR amplification time for SARS-CoV-2 to eight minutes. Read more
06 Apr 2020 | COVID-19

Image: SARS-CoV-2 (COVID-19) IgM/IgG Antibody Fast Detection Kit (Photo courtesy of ThermoGenesis Holdings, Inc.)

ThermoGenesis Develops Blood Test to Detect COVID-19 in Minutes

ThermoGenesis Holdings, Inc. (Rancho Cordova, CA, USA), which provides automated cell processing tools and services in the cell and gene therapy field, has developed an advanced point-of-care test that will allow rapid diagnosis of the COVID-19 virus, including asymptomatic cases, using just a single drop of blood without the need for special lab equipment and deliver results in less than 10 minutes. Read more
06 Apr 2020 | COVID-19

Image: Biotecon Diagnostics Acu-Corona COVID-19 Detection Kits (Photo courtesy of BIOTECON Diagnostics GmbH)

BIOTECON Expedites Launch of Viral RNA Extraction Kit for Detecting COVID-19

BIOTECON Diagnostics GmbH (Potsdam, Germany) has launched its newly-developed foodproof Magnetic Preparation Kit VI, which enables lab specialists to perform rapid, sensitive, and reliable RNA and DNA extraction from an array of different viruses. Read more
06 Apr 2020 | COVID-19

Image: The Oxford Nanopore MinION device (Photo courtesy of Oxford Nanopore Technologies).

Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples

Posterior oropharyngeal saliva samples are a non-invasive specimen more acceptable to patients and health-care workers. Read more
06 Apr 2020 | Microbiology

Image: The paper device for COVID-19 detection presents results that are visible to the naked eye: a green circle indicating positive and a blue circle negative (Photo courtesy of Cranfield University)

Rapid, Paper-Based Test Detects Coronavirus in Sewage and Wastewater

A team of British researchers has developed a rapid test to detect the COVID-19 virus, SARS-CoV-2, in sewage and wastewater as a means for gauging the level of infection within the community. Read more
06 Apr 2020 | Molecular Diagnostics

Mount Sinai Developing `End-to-End` Diagnostics Solution for COVID-19

Researchers and clinicians in microbiology, virology, pathology, molecular science, and immunology at the Icahn School of Medicine at Mount Sinai {(ISMMS) New York, NY, USA) and The Mount Sinai Hospital {(MSH) New York, NY, USA) are working on designing, validating, and implementing an “end-to-end” clinical pathology laboratory solution that will allow for the COVID-19 testing of approximately several hundred people per day in order to rapidly diagnose and help guide the selection of treatment and monitor disease course. Read more
04 Apr 2020 | COVID-19

Image: Applied Biosystems 7500 Fast Dx Real-Time PCR Instrument (Photo courtesy of Applied Biosystems)

Vela Diagnostics to Offer Manual ViroKey SARS-CoV-2 RT-PCR Test

Vela Diagnostics (Singapore) plans to offer its manual ViroKey SARS-CoV-2 RT-PCR Test after its validation is completed and is currently working with the US Food and Drug Administration (FDA) for securing Emergency Use Authorization (EUA) for the test. Read more
04 Apr 2020 | COVID-19

Cellink Relaunches Real-Time qPCR Instrument for COVID-19

CELLINK (Boston, MA, USA) has begun reselling its qPCR instrument which can be used for the quantification and genotyping of human viral pathogens, such as SARS-CoV-2. Read more
04 Apr 2020 | COVID-19

Channels

Clinical Chemistry

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Image: The high throughput immunochemistry cobas e 801 module (Photo courtesy of Roche Diagnostics).

Novel Method Developed to Estimate LDL Particle Size

Premature atherosclerotic disease commonly occurs in individuals with atherogenic dyslipidemia who share a phenotype characterized by centripetal obesity, insulin resistance, and physical inactivity.... Read more

Image: Factors associated with acute respiratory distress syndrome (ARDS) In COVID-19 identified (Photo courtesy of the Brian Orelli, PhD).

Factors Associated with ARDS in COVID-19 Identified

Patients with COVID-19 present primarily with fever, myalgia or fatigue, and dry cough. Although most patients are thought to have a favorable prognosis, older patients and those with chronic underlying... Read more

Image: A solid phase sandwich ELISA for the determination of Tenascin-C; higher levels are Associated with Cardiovascular Disease (Immuno-Biological Laboratories, Inc).

Higher Tenascin-C Levels Associated with Cardiovascular Disease

Although there are several known biomarkers for cardiovascular (CV) risk that have been proposed to improve risk stratification in diabetes, they have not been incorporated into international guidelines.... Read more

Image: Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy (Photo courtesy of Duke University).

Kidney Disease Reveals DNA Variants Associated with Diabetic Nephropathy

Diabetic kidney disease is a serious complication that develops in some people with both Type 1 and Type 2 diabetes. It affects the kidneys' ability to filter extra water and waste products from the body... Read more

Molecular Diagnostics

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Image: A new fluid analyzing platform allows for the isolation of circulating tumor cells (CTCs), which are formed during metastasis (Photo courtesy of NYU Abu Dhabi)

Hybrid Liquid Biopsy Platform Enables Tracking and Monitoring of Circulating Tumor Cells

By creating a hybrid microfluidic liquid biopsy platform that incorporates atomic force microscopy (AFM), cancer researchers have captured and characterized circulating tumor cells (CTCs), a technique... Read more

Image: The cobas Epidermal Growth Factor Receptor (EGFR) gene Mutation Test v2 (Photo courtesy of Roche).

Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported

Epidermal growth factor receptor (EGFR) gene mutations that confer sensitivity to tyrosine kinase inhibitors (TKI) in non-small cell lung carcinomas paved the way for a precision medicine approach in this... Read more

Genetic Testing Benefits Postmenopausal Women with Breast Cancer

Germline genetic testing for pathogenic variants (PVs) in cancer susceptibility genes after breast cancer diagnosis may inform cancer treatment, prevention, and testing of relatives. Postmenopausal women... Read more

Image: High magnification micrograph of hypertrophic decidual vasculopathy, as seen in pregnancy-induced hypertension (Photo courtesy of Wikimedia Commons)

Combined Maternal and Fetal Gene Variants Predict Pre-Eclampsia Risk

A genetic signature that combines certain maternal and fetal gene variants shows promise as a means for assessing risk of pregnant women to develop pre-eclampsia. Pre-eclampsia (PE) is a disorder of... Read more

Hematology

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Image: The XE-5000 Hematology Analyzer is a high volume analyzer that offers unique clinical parameters to aid in better patient care (Photo courtesy of Sysmex Corporation).

Prognostic Values of Platelet Parameters in Gynecological Tumors Patients

Gynecologic cancers often involve the uterus, ovaries, cervix, vulva, vagina, fallopian tubes, or the peritoneum. The most common gynecologic cancer in the USA is endometrial cancer, followed by ovarian cancer.... Read more

Image: Sacroiliac joint biopsy specimen of a 29 year old male patient with ankylosing spondylitis. The biopsy specimen shows a subchondral cellular infiltrate partly invading the cartilage. Fibroblasts and activated lymphocytes are seen in the infiltrate. In between are areas of calcification and bone formation (Photo courtesy of Professor J. Braun).

Fibrinogen-Albumin Ratio Correlated to Ankylosing Spondylitis Disease Activity

Ankylosing spondylitis (AS) is a systematic inflammatory autoimmune disease that primarily involves the spine and sacroiliac joints. Typically the joints where the spine joins the pelvis are also affected... Read more

Image: The Agilent 4200 TapeStation system is an established automated electrophoresis tool for DNA and RNA sample quality control (Photo courtesy of Agilent Technologies).

NGS Identifies Genomic Characteristics of Pediatric Leukemia

Pediatric leukemias have a diverse genomic landscape associated with complex structural variants, including gene fusions, insertions and deletions, and single nucleotide variants. Routine karyotype and... Read more

Image: The Gallios flow cytometer provides efficient acquisition of superior quality data from up to 10 colors with advanced optical design for enhanced sensitivity for multicolor assays (Photo courtesy of Beckman Coulter).

Minimal Residual Disease Assessed in AL Amyloidosis Patients

Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis in the USA. Despite achieving a hematologic complete response after treatment, many... Read more

Immunology

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Image: Photomicrograph of normal plasma cells from a bone marrow aspirate (Photo courtesy of Peter Anderson).

Molecule in Lymphatic System Implicated in Autoimmune Diseases

A healthy immune system defends the body against diseases and infection. When someone has an autoimmune disease, the immune system malfunctions and the body mistakenly attacks healthy cells, tissues and organs.... Read more

Image: Transmission electron micrograph of an isolate from a case of COVID-19, caused by the coronavirus SARS-CoV-2. The spherical viral particles, colorized blue, contain cross-sections through the viral genome, seen as black dots (Photo courtesy of Hannah A Bullock and Azaibi Tamin).

SARS-Cov-2 Specific Antibody Responses in COVID-19 Patients

The rapid identification of the etiology and the sharing of the genetic sequence of the virus, followed by international collaborative efforts initiated due to the emergence of SARS-CoV-2 have led to the... Read more

Image: MACS Technology is a fast and gentle method for the isolation of viable and functionally active cells by magnetic labeling (Photo courtesy of University of Konstanz).

Fetal Cell-Based NIPT Demonstrated by Droplet Digital PCR

Noninvasive testing techniques are often used for fetal diagnosis of genetic abnormalities, but are limited by certain characteristics, including non-informative results. Thus, novel methods of noninvasive... Read more

Image: This photomicrograph depicts T cells interacting with each other. Cell surfaces are labeled in red, cell nuclei in blue, and receptors mediating communication in green (Photograph courtesy of Immunity).

T Cells Function as A Team to Fight Infection

When faced with an infection, T cells normally follow a remarkably reproducible response pattern of expansion, contraction, and memory formation. Population-intrinsic and -extrinsic regulation of T cells... Read more

Microbiology

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Novel Rapid Test Developed for Detecting Carbapenemase

As a potent β-lactamase, carbapenemase can degrade almost all β-lactam antimicrobial drugs, including the carbapenems, regarded as the last line of therapy for many life-threatening infections.... Read more

Image: The image shows bacterial cells trapped in a three-dimensional microbead matrix (Photo courtesy of Wenrong He, Rochester Institute of Technology)

Novel Nanofluidic Device Traps and Concentrates Pathogenic Bacteria

A nanofluidic device containing stacked magnetic beads of different sizes has been developed to efficiently trap, concentrate, and retrieve Escherichia coli (E. coli) bacteria from liquid suspensions.... Read more

Image: This transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient in the United States (Photo courtesy of [U.S.] National Institute of Allergy and Infectious Diseases)

The COVID-19 Coronavirus Remains Viable for Hours or Days on Solid Surfaces

A recently published paper sheds light on how coronavirus spreads through the air and how long it remains viable on various solid surfaces. A novel coronavirus of zoonotic origin, SARS-CoV-2 (2019-nCoV)... Read more

Serial Procalcitonin Measurements Utilized in Hospitalized Community-Acquired Pneumonia

Community-acquired pneumonia (CAP) refers to pneumonia (any of several lung diseases) contracted by a person with little contact with the healthcare system. CAP, the most common type of pneumonia, is a... Read more

Pathology

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Image: Schematic diagram of a urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection study (Photo courtesy of the University of California, San Francisco).

Urine-Based Kidney Transplantation Rejection Risk Assay Launched

For kidney transplant recipients, prompt and accurate detection of transplant rejection is vital for timely intervention. Unfortunately, the gold standard for diagnosis of rejection is kidney biopsy, an... Read more

Image: Multitarget Stool DNA Screening has a high positive predictive value for colorectal neoplasia regardless of exposure to previous colonoscopy (Photo courtesy of Madeline Morr).

Multitarget Stool DNA Predicts Colorectal Neoplasia

Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases due to underlying genetic disorders. Screening is effective for preventing and decreasing deaths from... Read more

EGFR Mutation Assay Cartridges Evaluated

Lung cancer remains the leading cause of cancer deaths. The management of lung cancer has been aided by the better understanding of molecular mechanisms involved in its initiation and progression and increased... Read more

Combining Biomarkers Predicts Metastasis in Medullary Thyroid Carcinoma

Medullary thyroid carcinoma (MTC) is a neuroendocrine neoplasm originating from thyroid parafollicular C cells and accounts for only 5% of all thyroid cancers, but its malignancy is relatively high, causing... Read more

Lab Tech.

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Image: Electronic Nose Device Can Detect Esophageal Cancer Precursor (Photo courtesy of Radboud University Medical Center).

Esophageal Cancer Precursor Detected by Electronic Nose Device

Barrett's esophagus is a condition in which the lining of the esophagus changes, becoming more like the lining of the small intestine rather than the esophagus. This occurs in the area where the esophagus... Read more

Image: the Vivalytic multiplex PCR platform (Photo courtesy of Randox Laboratories)

Analyzer Platform for Simultaneous Detection of Multiple Sexually Transmitted Infections Is Now CE-marked

The British health diagnostic company Randox Laboratories (Crumlin, United Kingdom) announced receipt of CE-marking for its Biochip-based assay, which tests for 10 sexually transmitted infections (STIs)... Read more

Image: The VITROS XT 3400 Chemistry System (Photo courtesy of Ortho Clinical Diagnostics)

New Chemistry Analyzer Completes Ortho Clinical Diagnostics’ Catalogue of VITROS XT Solutions

Ortho Clinical Diagnostics (Raritan, NJ, USA) has announced the launch and availability of the VITROS XT 3400 Chemistry System, which completes the company’s catalogue of VITROS XT Solutions.... Read more

Image: Detection and quantification of procalcitonin and C‐reactive protein using detection of inflammatory biomarkers imager (DENIS) (Photo courtesy of Ecole Polytechnique Fédérale de Lausanne).

Optical Biosensor Reduces Time for Sepsis Diagnosis

New point‐of‐care diagnostic devices are urgently needed for rapid and accurate diagnosis, particularly in the management of life‐threatening infections and sepsis, where immediate treatment is key.... Read more

BioResearch

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Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

Cancer researchers developed a 29 gene–based weighted prognostic score for predicting event-free survival and overall survival of patients suffering from diffuse large B-cell lymphoma (DLBCL).... Read more

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction.... Read more

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. Methods currently used to diagnose... Read more

Image: Spiked rods of monosodium urate crystals photographed under polarized light from a synovial fluid sample. Formation of monosodium urate crystals in the joints is associated with gout (Photo courtesy of Wikimedia Commons).

Panel of Genetic Loci Accurately Predicts Risk of Developing Gout

A large GWAS (genome-wide association study) highlighted genetic loci associated with the metabolic regulation of serum levels of uric acid (urate) and identified a panel of 183 loci linked to the risk... Read more

Industry News

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New AI System Performs as Well as Expert Pathologists in Identifying Prostate Cancer

Researchers at the Karolinska Institutet (Stockholm, Sweden) and Tampere University (Tampere, Finland) have developed a method based on artificial intelligence (AI) for histopathological diagnosis and... Read more

Quest Diagnostics Acquires Blueprint Genetics

Quest Diagnostics (Secaucus, NJ, USA), a provider of diagnostic information services, has acquired Blueprint Genetics (Helsinki, Finland), a specialty genetic testing company with expertise in gene variant... Read more

Nova Biomedical Launches New BioProfile FLEX2 On-Line Autosampler

Nova Biomedical (Waltham, MA, USA) has launched the BioProfile FLEX2 On-Line Autosampler (OLS), a modular system that connects as many as 10 bioreactors to one FLEX2 analyzer for up to three weeks of walkaway,... Read more

Image: Analyticon Coagulyzer 100 (Photo courtesy of Analyticon)

Global Hematology Diagnostic Devices and Equipment Market to Reach USD 2.35 Billion by 2022

The global hematology diagnostic devices and equipment market was valued at about USD 1.9 billion in 2018 and is projected to grow to at a CAGR of 5.5% to USD 2.35 billion in 2022. The market growth is... Read more

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