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A Shared Passion for Positive Patient Outcomes: 2020 AACC Annual Scientific Meeting & Clin Lab Expo

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

21 Sep 2020 - 25 Sep 2020
Virtual Venue

EASD 2020 – 56th Annual Meeting of the European Association for the Study of Diabetes

30 Sep 2020 - 03 Oct 2020

BCLF 2020 - 28th Balkan Clinical Laboratory Federation Meeting

01 Oct 2020 - 02 Oct 2020
Virtual Venue

BSACI 2020 – Annual Conference of the British Society for Allergy and Clinical Immunology

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Key Biomarkers Could Identify Patients at Risk for Severe Reaction to COVID-19 Infection

Stroke Scans Could Reveal COVID-19 Infection

Study Finds T Cells Lead in Controlling SARS-CoV-2, Suggesting COVID-19 Vaccines Must Elicit Broad Immune Response

New Insight into Structural Mechanism of Coronavirus Receptor Binding to Aid Development of COVID-19 Treatments and Vaccines

New Generation of Long-Acting Immunotherapeutic Antivirals Aim to Prevent COVID-19/Flu ‘Twindemics’

New Portable PCR COVID-19 Test Kit from Visby Medical Secures FDA Emergency Use Authorization

FDA Publishes Comparative Performance Data for COVID-19 Molecular Diagnostic Tests

First-in-Class Rapid Diagnostic Test Measures COVID-19 Neutralizing Antibodies in Plasma and Serum

World's First Commercially Available Saliva-Based COVID-19 Test Detects Coronavirus in 3-10 Minutes

New CRISPR-Based Rapid Test Detects as Many Cases as Standard COVID-19 Diagnostic

Self-Swab COVID-19 Collection Kit Receives FDA EUA for Use by CLIA-Certified Laboratories

Roche Granted FDA Emergency Use Authorization for Cobas SARS-CoV-2 & Influenza A/B Test

Siemens Collaborates with CDC to Develop Process for Standardizing SARS-CoV-2 Assays

More COVID-19 News

Unique Antibody Profile Differentiates Gluten Sensitivity from Celiac Disease

Image: Histology of normal small intestinal mucosa in adequately treated celiac disease (A). Untreated coeliac disease shows the classic triad of infiltration of the epithelium with lymphocytes, crypt hyperplasia and villous atrophy (B) (Photo courtesy of Professor Jason Tye-Din, MBBS PhD).

Until recently, many doctors often dismissed the complaints of people who claimed to be sensitive to foods containing gluten but did not have celiac disease, a well-documented autoimmune disease triggered by exposure to the dietary protein found in wheat, rye, and barley. Read more
17 Sep 2020

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LINEAR CHEMICALS S.L.U

Unconventional T Cells in COVID-19 Patients Predicts Disease Outcome

17 Sep 2020

Quantitative Agglutination Determined on Automatic Hematology Analyzer

16 Sep 2020

Complex ABO Glycan Phenotypes Predicted by Lectin Microarrays

16 Sep 2020

Novel Blood Test Predicts Psychotic Disorders Before They Emerge

15 Sep 2020

Biosensing Platform Diagnoses Diseases Through Single Molecule Detection

15 Sep 2020

Industry Spotlight

2020 AACC Annual Scientific Meeting & Clinical Lab Expo to Be an All Virtual Event Due to Coronavirus Pandemic

The American Association for Clinical Chemistry (AACC Washington, DC, USA) has decided to hold the 2020 AACC Annual Scientific Meeting & Clinical Lab Expo as a virtual event, rather than as a live meeting, due to the ongoing coronavirus pandemic. Read more
25 Aug 2020

QIAGEN to Focus on Molecular Testing amidst Coronavirus Pandemic after Voluntary Public Takeover Offer by Thermo Fisher Falls Short

QIAGEN N.V. (Venlo, Netherlands) plans to continue executing its growth strategy aimed at creating significant value for shareholders and other stakeholders after the voluntary public takeover offer by Thermo Fisher Scientific Inc. Read more
14 Aug 2020

Awareness Technology Announces ChemWell RPR Analyzer - The Most Significant Innovation in Syphilis Testing in Last 30 Years

Awareness Technology, Inc. (Palm City, FL, USA) has announced the most significant innovation in syphilis testing in the last 30 years with the launch of the ChemWell RPR automated nontreponemal analyzer for the detection of syphilis. Read more
17 Jul 2020

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In Other News

New Portable PCR COVID-19 Test Kit from Visby Medical Secures FDA Emergency Use Authorization

A new portable PCR COVID-19 test kit has been granted Emergency Use Authorization (EUA) by the US Food and Drug Administration (FDA) for use in lab environments. Read more
18 Sep 2020 | COVID-19

Image: SARS-CoV-2 emerging from the surface of cells (Photo courtesy of NIAID)

New CRISPR-Based Rapid Test Detects as Many Cases as Standard COVID-19 Diagnostic

A newly-developed CRISPR-based test has shown improved sensitivity and can detect nearly as many cases as the standard COVID-19 diagnostic. Read more
18 Sep 2020 | COVID-19

FDA Publishes Comparative Performance Data for COVID-19 Molecular Diagnostic Tests

The US Food and Drug Administration (FDA Silver Spring, MD, USA) has published comparative performance data for some authorized COVID-19 molecular diagnostic tests. Read more
18 Sep 2020 | COVID-19

Self-Swab COVID-19 Collection Kit Receives FDA EUA for Use by CLIA-Certified Laboratories

The Food and Drug Administration (FDA) has granted Emergency Use Authorization (EUA) to a new COVID-19 self-collection kit, enabling public health and large private labs to increase access to testing. Read more
17 Sep 2020 | COVID-19

First-in-Class Rapid Diagnostic Test Measures COVID-19 Neutralizing Antibodies in Plasma and Serum

A new rapid diagnostic test is expected to be the market’s first COVID-19 rapid diagnostic test for measuring the levels of functional SARS-CoV-2 neutralizing antibodies in a lateral flow assay format. Read more
17 Sep 2020 | COVID-19

Image: The cobas SARS-CoV-2 & Influenza A/B Test (Photo courtesy of Roche)

Roche Granted FDA Emergency Use Authorization for Cobas SARS-CoV-2 & Influenza A/B Test

Roche (Basel, Switzerland) has received Emergency Use Authorization (EUA) from the US Food and Drug Administration (FDA) for a rapid version of its Cobas SARS-CoV-2 & Influenza A/B test. Read more
17 Sep 2020 | COVID-19

Image: ZandCell COVID-19 Rapid Antigen Test kit (Photo courtesy of ZandCell LLC)

World's First Commercially Available Saliva-Based COVID-19 Test Detects Coronavirus in 3-10 Minutes

ZandCell LLC (Jackson, WY., USA) has launched a fast, reliable, and affordable COVID-19 saliva based rapid antigen test kit to be used in and by airports, governments, states, hospitals, healthcare workers and, sports events, to administer testing for the virus. Read more
16 Sep 2020 | COVID-19

Image: Siemens’ collaboration with the CDC and the JRC will develop a novel process for standardizing SARS-CoV-2 assays by anchoring each protein to a neutralization antibody titer - a level of antibody present to block virus from entering cells in laboratory experiments (Photo courtesy of Siemens Healthineers)

Siemens Collaborates with CDC to Develop Process for Standardizing SARS-CoV-2 Assays

Siemens Healthineers (Erlangen, Germany) has entered into a collaboration with the US Centers for Disease Control and Prevention (CDC Atlanta, GA, USA) and the JRC (Joint Research Centre) of the European Commission on a research project to develop a novel process for standardizing SARS-CoV-2 assays. Read more
16 Sep 2020 | COVID-19

Global Swab and Viral Transport Medium Market Growing Rapidly Due to Rising Demand from COVID-19 Pandemic

The global swab and viral transport medium market (VTM) was valued at USD 0.9 billion in 2019 and is projected to expand at a CAGR of ~3% from 2020 to 2030 to reach USD 2. Read more
14 Sep 2020 | COVID-19

Image: Histopathology of the coronary artery demonstrating an intramural hematoma compressing the vessel lumen from outside from a patient with spontaneous coronary artery dissection (Photo courtesy of Professor Mary N Sheppard, MBBCh FRCPath).

Genetics Influence Risk for Spontaneous Coronary Artery Dissection

Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of myocardial infarction (MI) in young and otherwise healthy women, for which the etiology is incompletely understood. Read more
14 Sep 2020 | Molecular Diagnostics

Image: Using advanced biochemical analysis of patient serum, researchers found signatures that help predict which patients are at highest risk of dying from S. aureus bacteremia, a blood infection (Photo courtesy of University of California, San Diego)

Proteomics-Based Diagnostic Test Predicts Risk of Dying from Staphylococcus aureus Bacteremia

A diagnostic approach that integrates proteomic and metabolomic techniques enabled the identification of biomarkers that could predict which patients had the highest risk of dying from Staphylococcus aureus bacteremia. Read more
14 Sep 2020 | Molecular Diagnostics

Image: Newborn Exome Sequencing Could Augment Other Newborn Screening Approaches (Photo courtesy of Sushytska).

Sequencing Could Augment Other Newborn Screening Methods

Newborn screening (NBS) was established as a public health program in the 1960s and is crucial for facilitating detection of certain medical conditions in which early intervention can prevent serious, life-threatening health problems. Read more
14 Sep 2020 | Molecular Diagnostics

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Clinical Chemistry

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Image: Impact of maternal HbA1c levels ≤ 6% and race in non-diabetic pregnancies on birth weight and early neonatal hypoglycemia (Photo courtesy of Diabetes Self-Management).

Molecular Diagnostics

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Image: Schematic diagram of fetal and maternal DNA as studied in the detection and characterization of jagged ends of double-stranded DNA in plasma (Photo courtesy of Ariosa Diagnostics).

Jagged Ends of Double-Stranded DNA Characterized

Cell-free DNA in plasma has been used for noninvasive prenatal testing and cancer liquid biopsy. The physical properties of cell-free DNA fragments in plasma, such as fragment sizes and ends, have attracted... Read more

MicroRNA-Based Liquid Biopsy Assay for Early Diagnosis of Head and Neck Cancer

A microRNA-based liquid biopsy assay has been developed that enables early diagnosis of oropharyngeal squamous cell carcinoma, a disease causing hundreds of thousands of fatalities each year.... Read more

New Diagnostic Test Assesses Suitability for Immune Checkpoint Inhibitor Immunotherapy

A newly developed diagnostic procedure enables doctors to predict whether a cancer patient will benefit from immune checkpoint inhibitor immunotherapy. Checkpoint inhibitor therapy is a form of cancer... Read more

Rapid CRISPR/Cas Assay for Diagnosis of Viral Fevers in Low-Tech Environments

Rapid diagnostic tests for Ebola and Lassa fever viruses based on the RNA-targeting CRISPR/Cas13a complex have been tested successfully under field conditions in several African countries.... Read more

Hematology

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Positive Lymphocyte Gene Rearrangement Evaluated for Hematologic Malignancies

The diagnosis of a lymphoid malignancy requires the establishment of monoclonality of a lymphocyte population through morphologic assessment and laboratory testing, such as flow cytometry, immunohistochemistry,... Read more

Image: A blood film with a normal mature lymphocyte with a single large nucleus is seen on the left, compared to two segmented neutrophils on the right with multiple nuclear lobes. The lymphocytes are decreased in comorbid diabetes and COVID-19 patients (Photo courtesy of Ed Reschke).

Lymphocyte Count Correlated to Comorbid Diabetes and COVID-19

The coronavirus disease (COVID-19) that erupted in China since December 2019 and has gradually spread throughout the world. At present, it has caused tens of thousands of deaths, and the efficacy of certain... Read more

Clonal Hematopoiesis Prevalence Determined in Healthy Donors

Clonal hematopoiesis of indeterminate potential (CHIP) is defined as the presence of a clone at more than 2% of variant allele frequency (VAF) in peripheral blood (PB) of individuals with no evidence of... Read more

Image: Photomicrograph of Hodgkin lymphoma (HL), from a fine needle aspiration of a lymph node, which shows a mixture of cells common in HL: Eosinophils, Reed-Sternberg cells, Plasma cells, and Histocytes (Photo courtesy of Nephron).

Hodgkin Lymphoma Therapy Response Linked to T-Cell Receptor Repertoire

Hodgkin lymphoma (HL) is a type of lymphoma in which cancer originates from a specific type of white blood cells called lymphocytes. Symptoms may include fever, night sweats, and weight loss.... Read more

Immunology

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New Gold and Copper Nanoshell-Enhanced Immunoblotting Technique Makes POC Diagnosis of Tuberculosis Easier

A team of researchers have developed a straightforward and naked-eye-sensitive nanoshell-enhanced immunoblotting technique to detect Mycobacterium tuberculosis (MTB) antigen 85B (Ag85B).... Read more

Image: Schematic diagram of the immunoassay based on proximity extension assay (PEA) technology (Photo courtesy of Olink Proteomics).

Six Biomarkers Predict Severity of COVID-19

Coronavirus disease 2019 patients admitted to the ICU have high mortality. The host response to coronavirus disease 2019 has only been partially elucidated, and prognostic biomarkers have not been identified.... Read more

Image: The RF direct latex tests for the detection of rheumatoid factor (RF) in serum (Photo courtesy of VedaLab).

Specificity of Rheumatoid Factor Detected by Latex Fixation Compared

Rheumatoid arthritis is a chronic inflammatory and autoimmune disorder that can affect more than just the joints. In some people, the condition can damage a wide variety of body systems, including the... Read more

Image: Mass cytometry by time of flight uses CyTOF technology to enable deep profiling of translational and clinical samples across a range of cell surface and intracellular markers (Photo courtesy of University of Virginia).

Adaptive Immune Cells in Ulcerative Colitis Revealed by Single-Cell Analyses

Inflammatory bowel disease encompasses a spectrum of complex intestinal disorders characterized by dysregulated innate and adaptive immune responses to gut microbiota in genetically susceptible hosts.... Read more

Microbiology

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Loop-Mediated Isothermal Amplification Kit Detects Chagas Disease

Chagas disease (CD), also known as American trypanosomiasis, is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that affects about six to seven million people worldwide,... Read more

Traveler's Diarrhea Among Soldiers Linked to Gut Microbiome Changes

Travelers’ diarrhea (TD) is the most prevalent illness encountered by deployed military personnel and has a major impact on military operations, from reduced job performance to lost duty days.... Read more

Image: The Genie III instrument was used for the reverse transcriptase loop-mediated isothermal amplification-assay called N1 gene Single Tube Optigene LAMP (N1-STOP-LAMP) for COVID-19 (Photo courtesy of OptiGene Ltd).

Loop-Mediated Isothermal Amplification-Assay Rapidly Diagnoses COVID-19

The SARS-CoV-2 (COVID-19) pandemic of 2020 has resulted in unparalleled requirements for RNA extraction kits and enzymes required for virus detection, leading to global shortages. This has necessitated... Read more

$This photomicrograph of a Gram-stained urethral smear specimen, reveals some of the histopathology in an acute case of gonococcal urethritis, caused by the Gram-negative bacterium, Neisseria gonorrhoeae. (Image courtesy of [U.S.] Centers for Disease Control and Prevention\'s Public Health Image Library)$

Diagnostic Test Identifies Resistance Mutation that Enables Use of Inexpensive, Single Dose Gonorrhea Drug

By detecting the mutated gene responsible for resistance to the drug ciprofloxacin, it is possible to identify gonorrhea patients who can be cured by a single oral dose of this drug. Gonorrhea, a sexually... Read more

Pathology

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Image: De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection (Photo courtesy of UT Southwestern Medical Center).

Cancer-Associated T Cell Receptors Evaluated for Malignancy Detection

A key goal in oncology is diagnosing cancer early, when it is more treatable. Despite decades of progress, early diagnosis of asymptomatic patients remains a major challenge. Most methods for this involve... Read more

Signatera assays are the first circulating tumor DNA (ctDNA) tests custom-built for each patient based on the unique mutations in an individual patient’s tumor (Photo courtesy of Natera Inc).

Circulating tumor DNA Test Predicts Immunotherapy Response

Immunotherapy is a type of cancer treatment that helps the immune system fight cancer. Although some cancer patients derive dramatic and sustained benefit from immunotherapy, most cancer patients do not.... Read more

Image: The Aperio AT2 is the ideal digital pathology slide scanner for high-throughput clinical laboratories, delivering precise eSlides with low rescan rate (Photo courtesy of Leica Biosystems).

Digital Pathology Solution Resolves the Tissue Floater Conundrum

In routine clinical practice, pathologists may encounter extraneous pieces of tissue on glass slides that could be because of contamination from other specimens. These are typically called tissue floaters.... Read more

Image: The benchtop SH800S cell sorter permits sorting of a wide range of cell sizes for many applications using the 70-μm, 100-μm, and 130-μm microfluidic sorting chips (Photo courtesy of Sony Biotechnology).

Pediatric Ependymoma Single-Cell Analysis Signatures Linked to Outcomes

An ependymoma is a tumor that arises from the ependyma, a tissue of the central nervous system. Usually, in pediatric cases the location is intracranial, while in adults it is spinal. The common location... Read more

Technology

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Image: A test tube contains saliva that can be tested for the heart attack biomarker cardiac troponin (Photo courtesy of karenfoleyphoto).

Saliva Test Fast Tracks Heart Attack Diagnosis

Heart attacks need urgent diagnosis, followed by treatment to restore blood flow to blocked arteries. Diagnosis is based on symptoms (such as chest pain), an electrocardiogram (ECG) and a blood test for... Read more

Image: Schematic diagram of the OvCa-Chip microsystem that recreates vascular endothelium–mediated platelet extravasation in ovarian cancer (Photo courtesy of Texas A&M College of Engineering).

Microfluidic Device Explores Ovarian Cancer Interactions

In many cancers, platelet interactions with circulating tumor cells and their role in metastasis have been studied extensively. In ovarian cancer, platelet extravasation into the tumor and resulting metastasis... Read more

$The TriVersa NanoMate LESA uses chip-based electrospray ionization technology that combines the benefits of liquid chromatography, mass spectrometry, chip-based infusion, fraction collection, and direct surface analysis into one integrated ion source platform (Photo courtesy of Advion BioSciences).$

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