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Trending Articles

Rhinomed Announces European Launch of Revolutionary New Swab for Testing Children for Respiratory Diseases

Independent Subtype of Idiopathic Multicentric Castleman Disease Defined

Leica Biosystems Acquires Cell IDx, Expanding Offerings in Multiplexed Tissue Profiling

New Molecular Microscopy Tool Uncovers Breast Cancer Spread

Self-Supervised AI Improves Diagnostic Accuracy for Melanoma with Low Pathologist Agreement

Mast Group Enters into Multi-Country Distribution Agreement for Nanomix's eLab System

Roche Introduces Digital Health Solutions Under Navify Brand

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Rhinomed Announces European Launch of Revolutionary New Swab for Testing Children for Respiratory Diseases

Fecal Immunochemical Test a Less Expensive Alternative for Colorectal Cancer Screening

Portable, Sample to Answer PCR Device Delivers Accurate Results in 30 Minutes at Point of Need

Bosch Demonstrates Vivalytic All-In-One PCR Analyzer at MEDICA 2022

Biovendor Group Presents CLIA Solution for Complex Diagnostics at MEDICA 2022

Diatron Exhibits Advanced Hematology and Clinical Chemistry Analyzers at MEDICA 2022

Immundiagnostik AG Presents New PCR Test MutaPLEX RespiraScreen4_Diff_seqc at MEDICA 2022

Eurotrol Presents the Future of Blood Gas Controls at MEDICA 2022

Owen Mumford Presents Cutting-Edge Capillary Blood Sampling Devices for POC Testing

Novel Device Detects COVID-19 Antibodies in Five Minutes

CRISPR-Powered COVID-19 Test Detects SARS-CoV-2 in 30 Minutes Using Gene Scissors

Gut Microbiome Dysbiosis Linked to COVID-19

Novel SARS CoV-2 Rapid Antigen Test Validated for Diagnostic Accuracy

New COVID + Flu + R.S.V. Test to Help Prepare for `Tripledemic`

AI Takes Guesswork Out Of Lateral Flow Testing

Events

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

05 Dec 2022 - 08 Dec 2022

BSI Congress 2022 – British Society for Immunology

06 Dec 2022 - 08 Dec 2022

8th Annual Conference of the Saudi Society for Clinical Chemistry

10 Dec 2022 - 13 Dec 2022

64th Annual Meeting & Exposition of the American Society of Hematology (ASH)

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AI Diagnostic Tool Improves Cancer Detection in Cystoscope Images of Bladder

Non-Invasive 3D Imaging System Enables Physicians to Identify Origin of Arrhythmias Pre-Procedure

Low Pressure Insufflation for Surgical Laparoscopic Procedures Improves Patient Outcomes

Next-Gen POC Whole Blood Hemostasis System Recognizes Specific Needs of EDs and ORs

Global Multiparameter Patient Monitoring Systems Market Driven by Rising Chronic Illnesses

ctDNA-Based MRD Test to Detect As Few As One Mutant Molecule in a Million DNA Molecules

Image: Liquid biopsy approach delivers unparalleled sensitivity and specificity for detection of low-frequency mutant molecules (Photo courtesy of Pexels)

A best-in-class personalized cancer diagnostic test that is currently under development and planned for 2023 commercialization can detect as few as one mutant molecule in a million DNA molecules, positioning it as the most sensitive ctDNA-based MRD test for use in solid tumors. Read more
02 Dec 2022

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Study Identifies Optimal Blood Tests for Detection and Treatment of Early Stage Alzheimer’s

02 Dec 2022

Blood Test for Protein Biomarker Could Detect Pancreatic Cancer at Very Early Stage

02 Dec 2022

Novel Digital Morphology Analyzer Performance Evaluated

01 Dec 2022

Laboratory Features of Trichinellosis and Eosinophilia Threshold Determined

01 Dec 2022

First-Ever Urine Biomarker Test Could Reveal Early-Stage Alzheimer’s

01 Dec 2022

Industry Spotlight

Leica Biosystems Acquires Cell IDx, Expanding Offerings in Multiplexed Tissue Profiling

Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging (Nussloch, Germany), has acquired Cell IDx, Inc. Read more
09 Nov 2022

Roche Introduces Digital Health Solutions Under Navify Brand

Roche (Basel, Switzerland) has announced that its digital health portfolio will now be available under the navify brand. Read more
08 Nov 2022

Werfen to Acquire Transfusion and Transplant Diagnostics Innovator for Around USD 2 Billion

Werfen (Barcelona, Spain) has agreed to acquire Immucor, Inc. (Norcross, GA, USA), a privately held corporation with a global presence in transfusion and transplant in vitro diagnostics, at a purchase price of approximately USD 2 billion. Read more
08 Nov 2022

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In Other News

Image: 3E segmentation of ginger-root shaped necrotic lesions (yellow) and surrounding vasculature (red) (Photo courtesy of Africa Health Research Institute)

High-Resolution 3D Imaging Reveals Tuberculosis and COVID-19 Lung Lesions

Gross anatomy reveals three-dimensional shapes of pathology at a large scale. Histology, in contrast, reveals the microscopic anatomy of biological structures. Read more
01 Dec 2022 | Pathology

Image: The 10X Genomics Chromium Single Cell Gene Expression Solution (Photo courtesy of Technion Israel Institute of Technology)

Immune Microenvironment Characterized in Multiple Myeloma Progression

Multiple myeloma (MM) is a malignant disease of plasma cells (PCs) that reside within the bone marrow (BM). Read more
30 Nov 2022 | Hematology

Image: Liquid biopsies could predict survival odds for patients with metastatic cancer (Photo courtesy of Michigan Medicine)

Blood Tests Could Predict Survival Odds for Patients with Metastatic Cancer

As cancers grow and potentially spread to new parts of the body, they often shed cells and DNA into the blood stream. Read more
30 Nov 2022 | Molecular Diagnostics

Image: PepSeq is a fully in vitro platform for highly multiplexed serology using customizable DNA-barcoded peptide libraries (Photo courtesy of Northern Arizona University)

New Serological Test Could Search for Viral Triggers of Diseases

A new serological test can not only help humanity prepare for and respond to the next pandemic, but it also can be pivotal in the search for viral triggers of diseases like diabetes and celiac disease. Read more
30 Nov 2022 | Molecular Diagnostics

Image: Structure of zinc oxide modified with spike protein and its interaction with antibodies in sample (Photo courtesy of Karin Regina Leite de Oliveira/DK design)

Novel Device Detects COVID-19 Antibodies in Five Minutes

Rapid, cheap and accurate tests continue to be essential for epidemiological surveillance and for health services to monitor and contain the spread of SARS-CoV-2. Read more
30 Nov 2022 | COVID-19

Image: Antiphospholipid Antibodies Evaluated in Autoimmune Thyroid Diseases (Photo courtesy of VisitHealth limited)

Antiphospholipid Antibodies Evaluated in Autoimmune Thyroid Diseases

Autoimmune thyroid diseases (AITD) is the most common organ-specific autoimmune disease, mainly caused by genetic predisposition, environmental factors and dysfunction in the microbiome. Read more
29 Nov 2022 | Immunology

Image: ELISA kit for liver-type fatty acid–binding protein (L-FABP). The level of L-FABP present in urine reflects the level of renal tubular dysfunction (Photo courtesy of Sekisui Medical Co)

Urinary Biomarkers Predict Weaning From Acute Dialysis Therapy

Acute kidney injury is associated with a higher risk of chronic kidney disease (CKD), end-stage renal disease, and long-term adverse cardiovascular effects. Read more
29 Nov 2022 | Clinical Chem.

Image: The multiplex chip can measure the viral load in a nasal swab (Photo courtesy of University of Freiburg)

CRISPR-Powered COVID-19 Test Detects SARS-CoV-2 in 30 Minutes Using Gene Scissors

CRISPR-Cas is versatile: Besides the controversial genetically modified organisms (GMOs), created through gene editing, various new scientific studies use different orthologues of the effector protein ‘Cas’ to detect nucleic acids such as DNA or RNA. Read more
29 Nov 2022 | COVID-19

Image: Juno HAZEL is an innovative solution to increase accessibility and affordability of NIPS (Photo courtesy of Juno Diagnostics)

Blood-Based NIPS Test Improves Access to Genetic Testing

Juno Diagnostics (San Diego, CA, USA) has launched Juno Hazel, a non-invasive prenatal screening (NIPS) solution enabled from finger-prick amounts of blood. Read more
29 Nov 2022 | Molecular Diagnostics

Image: The NGAL Test is a tool for risk assessment of kidney damage (Photo courtesy of BioPorto)

AKI Biomarker Test Assesses Risk of Kidney Damage in Critically Ill Patients

Acute kidney injury (AKI) is a rapid loss of kidney function which typically happens as a complication of another serious illness or intervention. Read more
29 Nov 2022 | Clinical Chem.

Image: Corticobasal degeneration (CBD): diagram of the basal ganglia (in red) and related structures (in blue) within the brain. Basal ganglia along with cerebral cortex are involved in this condition (Photo courtesy of Wikimedia Commons)

Two Tau Variants Distinguish Corticobasal Degeneration from Other Tauopathies

Biomarkers have been found that identify, with up to 89% accuracy, individuals with the primary tauopathy, corticobasal degeneration. Read more
28 Nov 2022 | Molecular Diagnostics

Image: A cheap blood test could improve diagnosis of myocarditis (Photo courtesy of Queen Mary University of London)

First-Ever Blood Test Could Detect Deadly Heart Inflammation Within Hours

Myocarditis, or inflammation of the heart muscle, is a difficult condition to diagnose. Symptoms include a temperature, fatigue, chest pain and shortness of breath, which can all be easily mistaken for other conditions. Read more
25 Nov 2022 | Molecular Diagnostics

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Clinical Chem.

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Image: Equivalence of Genetically Elevated LDL and Lipoprotein(a) on Myocardial Infarction (Photo courtesy of Viborg Regional Hospital)

Familial Hypercholesterolemia Patients With ACD Have Elevated Lipoprotein(a)

Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein (LDL cholesterol), in the blood and early cardiovascular... Read more

Image: Thermo Scientific BRAHMS KRYPTOR Compact Plus Automated Immune Analyzer (Photo courtesy of machinio)

Circulating Angiogenic Factor Levels Predict Hypertensive Disorders of Pregnancy

Preeclampsia is the most common hypertensive disorder associated with pregnancy. The severe form of the disease can lead to dangerously high blood pressure, organ failure, vision loss or even stroke.... Read more

Image: A Human Lipocalin-2/ neutrophil gelatinase-associated lipocalin (NGAL) sandwich ELISA kit (Photo courtesy of Epitope Diagnostics Inc.)

Urine Neutrophil Gelatinase-Associated Lipocalin Predicts Acute Kidney Injury

Despite the increasing heterogeneity of etiology, making a definitive and timely diagnosis of acute kidney injury (AKI) remains challenging. Currently, the diagnosis of AKI is still based on elevated serum... Read more

New Blood Cholesterol Testing System Is Cheaper, More Efficient, and Faster

Total cholesterol contained in the body within normal limits is an important substance, without which the proper functioning of the body is impossible. Elevated blood cholesterol is a symptom of a number... Read more

Molecular Diagnostics

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Image: UriFind is a urine-based, non-invasive molecular test for detection of bladder cancer (Photo courtesy of Pexels)

Urine-Based, Non-Invasive Molecular Test Accurately Detects Bladder Cancer

Bladder cancer is a common type of cancer with a high recurrence rate. It has an estimated 84,000 new cases, and 17,300 deaths in the U.S. in 2021. The majority (>90%) of bladder cancer cases are urothelial... Read more

Image: A micrograph showing cells with abnormal p53 expression (brown) in a brain tumor (Photo courtesy of Wikimedia Commons)

Altered Ratios of p53 Isoforms Predict Response of Breast Tumors to Chemotherapy

Alterations in the distribution of p53 isoforms are predictive of the likelihood that a breast tumor will respond to treatment with the chemotherapeutic drug doxorubicin. The regulatory protein p53 is... Read more

Image: A blood test for people with high risk of breast cancer could diagnose the disease at early stage (Photo courtesy of Pexels)

Blood Test Could Screen for Changes in Proteins Prior to Breast Cancer Diagnosis

Researchers have found changes in the levels of particular proteins in people’s blood up to two years before they were diagnosed with breast cancer. The study could form the basis of blood testing for... Read more

Image: TruSight Lymphoma 40 uses expert-defined content and proven next-generation sequencing (NGS) technology to identify somatic variants associated with lymphomas (Photo courtesy of Illumina)

Tumor Biopsies Analysis Performed on Newly-diagnosed B-cell Neoplasms

Comprehensive genomic analyses of tumor biopsies from patients with newly-diagnosed germinal center B cell (GCB) diffuse large B cell/high grade B cell lymphoma (DLBCL/HGBL) have identified molecular subtypes... Read more

Hematology

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Image: The compact xMAP INTELLIFLEX system is a flow-based, multiplex platform that simplifies the workflow by combining the established performance of xMAP technology (Photo courtesy of Thermo Fisher Scientific)

Assay Developed to Measure Anti-Factor VIII Antibodies

Hemophilia is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a longer time after an injury,... Read more

Myelodysplastic Syndrome Diagnosed With Peripheral Blood Samples

Myelodysplastic syndromes (MDS) encompass a heterogeneous group of clonal bone marrow neoplasms, with a median age at diagnosis of 70 years. MDS are characterized by recurrent cytogenetic and molecular... Read more

Image: Histopathology of lymph node tissue from a person with idiopathic multicentric Castleman disease. Increased number of blood vessels and smaller germinal centers where immune cells mature in the lymph node, which are two of the pathology features needed to make the diagnosis (Photo courtesy of David Fajgenbaum, MD)

Independent Subtype of Idiopathic Multicentric Castleman Disease Defined

Multicentric Castleman disease (MCD) comprises a heterogeneous group of rare disorders that exhibit generalized symptoms such as swelling of lymph nodes, anemia, fever, and fatigue. Idiopathic multicentric... Read more

Image: The Applied Biosystems 96 well Veriti Thermal Cycler (Photo courtesy of Fisher Scientific)

Accurate Genetic Assay Identifies Human Neutrophil Antigen 2 Deficiency

Human Neutrophil Antigen 2 (HNA-2) is one of the most important neutrophil antigens implicated in a number of human disorders. HNA-2 deficiency or HNA-2 null is a common phenotype observed in 3%–5% of US citizens.... Read more

Immunology

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Image: Enzyme-linked immunosorbent assay were used to measure serum levels of IL-37, IL-38, and Vitamin D (Photo courtesy of MyBioSource Inc)

Interleukins and Vitamin D Evaluated in Women With Graves' Disease

Graves' disease (GD), an autoimmune disorder specific to the thyroid, is the leading cause of hyperthyroidism due to an enlarged and hyperactive thyroid gland, associated with extra-thyroidal manifestations,... Read more

Image: Infections by Epstein-Barr virus usually cause no symptoms, but a growing body of evidence suggests it plays a role in multiple sclerosis (Photo courtesy of Kateryna Kon, MD, PhD)

More Evidence for Epstein - Barr virus' Role in MS Found

The Epstein-Barr virus (EBV) is a common virus that causes glandular fever (infectious mononucleosis), usually in teenagers and young adults. It has been proposed as a possible trigger for multiple sclerosis,... Read more

Immune Reaction to Gut Bacterium May Trigger Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune condition in which the immune system attacks the tissues of the joints, especially in the knees, hands, and wrists. This causes inflammation and painful swelling.... Read more

Image: Immune dysregulation associated with Lyme disease could enable its accurate and prompt treatment (Photo courtesy of Pexels)

Immunoaffinity Technology Distinguishes Between Lyme Disease Infection States and Tracks Treatment Response

Lyme disease is the most prevalent vector-borne disease in the U.S., with an estimated 476,000 annual cases. Current diagnostics for this disease and complicated and rely on indirect methods that suffer... Read more

Microbiology

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Image: Ring-form trophozoites of Plasmodium vivax in a thin blood smear (Photo courtesy of Centers for Disease Control and Prevention)

Immune Regulators Predict Severity of Plasmodium vivax Malaria

Cytokines and chemokines are immune response molecules that display diverse functions, such as inflammation and immune regulation. In Plasmodium vivax infections, the uncontrolled production of these molecules... Read more

Image: The TaqPath Enteric Bacterial Select Panel is CE marked, For In Vitro Diagnostic Use (Photo courtesy of Pexels)

New Test Leverages PCR Technology to Detect Gastrointestinal Bacteria within Two Hours

A new test leverages polymerase chain reaction (PCR) technology to detect common gastrointestinal (GI) bacteria and returns results in about two hours with more than 98% sensitivity and specificity.... Read more

MRSA/SA PCR Rapid Test Quickly Diagnoses Methicillin Resistance at Point of Care

Methicillin-resistant (MRSA) is a major multi-resistant nosocomial pathogen worldwide with the WHO estimating that the mortality rate of patient infection rates is around 50% higher compared with patients... Read more

$Image: Candida auris is a type of fungus and can cause a severe infection in hospital or nursing home patients (Photo courtesy of UCSF Benioff Children\'s Hospital)$

Surveillance Provides Real-Time Information on Candida auris Outbreak

Candida auris is an emerging fungal pathogen causing outbreaks in healthcare facilities. C. auris can cause invasive candidiasis (fungemia) in which the bloodstream, the central nervous system, and internal... Read more

Pathology

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New Molecular Microscopy Tool Uncovers Breast Cancer Spread

Breast cancer commonly starts when cells start to grow uncontrollably, often due to mutations in the cells. Overtime the tumor becomes a patchwork of cells, called cancer clones, each with different mutations.... Read more

Self-Supervised AI Improves Diagnostic Accuracy for Melanoma with Low Pathologist Agreement

Study results on new artificial intelligence (AI) that predicts diagnostic agreement for melanoma highlight the potential of the technology to improve diagnostic accuracy for this deadliest form of skin... Read more

Image: Researchers are using AI techniques to improve pathology workflow (Photo courtesy of Pexels)

Artificial Intelligence Methods Could Replace Histochemical Staining

In the hospital, there is a group of doctors who use tissue samples as "evidence materials", analyze the evidence using knives, slicers and microscopes to extract clues from the tissue samples, and provide... Read more

Image: Claire Carter, Ph.D., an expert in MALDI, led the new research (Photo courtesy of CDI)

Advanced Mass Spectrometry Could Provide Microscopic Clues to Beating Deadly Brain Tumors

Glioblastoma is one of the most difficult cancers, let alone diseases, to treat. The brain tumor presents a median survival rate of just 12 to 15 months. The cancer is especially hard to beat, since it... Read more

Technology

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Revolutionary, Non-Invasive Technique Measures Glucose Levels Without Drawing Blood

More than 400 million people worldwide are living with diabetes and they still suffer from pricking their fingers multiple times a day to check their blood glucose levels. One of the main aims of diabetes... Read more

Image: The Continuity transportable mass spectrometer brings high-sensitivity and large mass range to chemical analysis in the field (Photo courtesy of BaySpec)

Immunoassay, Mini Mass Spec Combined for Malaria Detection

Currently, several different technologies are available for diagnosing malaria, but each has drawbacks. PCR, for instance, is highly sensitive and specific, but it requires upfront sample processing and... Read more

$Image: Researchers are exploring the use of ML for a minimally invasive system to detect Alzheimer\'s disease (Photo courtesy of NIH)$

Biosensing Platform Combined with Machine Learning to Enable Minimally-Invasive Detection of Alzheimer's

Alzheimer's disease is a severe neurodegenerative disorder characterized by progressive memory, cognitive impairment and personality changes, which can further evolve to dementia and death.... Read more

Image: Schematic of the intelligent impedance system, consisting of a parallel impedance cytometry and a machine learning-based detection system (Photo courtesy of Yaxiaer Yalikun, PhD)

Parallel Impedance Cytometry Screens Bacterial Cells in Real Time

Antibiotic-resistant infections are responsible for killing over a million people worldwide every year. Central to managing resistant infections is quickly identifying an appropriate treatment to which... Read more

BioResearch

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Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

A genomics-based blood test can predict likelihood that a baby suffering hypoxia at birth will suffer serious nervous disorders such as cerebral palsy or epilepsy at a later stage of development.... Read more

Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

Cancer researchers developed a 29 gene–based weighted prognostic score for predicting event-free survival and overall survival of patients suffering from diffuse large B-cell lymphoma (DLBCL).... Read more

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction.... Read more

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. Methods currently used to diagnose... Read more

Industry

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Image: Nanōmix eLab is a mobile, hand-held immunoassay and chemistry diagnostic system (Photo courtesy of Nanomix)

Mast Group Enters into Multi-Country Distribution Agreement for Nanomix's eLab System

Mast Group Limited (Liverpool, UK) and Nanomix (Emeryville, CA, USA) have entered into a multi-region distribution agreement wherein Mast will market and distribute the Nanōmix eLab system in the UK, Germany,... Read more

Image: Numares AXINON System (Photo courtesy of Numares)

AI-Enabled Diagnostic Testing Could Become More Accurate and Reliable than Current Tests

An expanded collaboration between two industry leaders will pave the way for the development of AI-enabled diagnostic testing that is more accurate and reliable than current U.S. tests for patients with... Read more

Image: The global infectious respiratory disease diagnostics market is expected to reach USD 43.6 billion by 2030 (Photo courtesy of Pexels)

Global Infectious Respiratory Disease Diagnostics Market Driven by New Multiplex PCR Tests and POC Products

The global infectious respiratory disease diagnostics market size is expected to reach USD 43.6 billion by 2030, driven by an increase in the prevalence of infectious respiratory diseases and initiatives... Read more

Image: The Binding Site has entered into an agreement to combine with Thermo Fisher Scientific (Photo courtesy of The Binding Site Group)

UK's Binding Site to Be Acquired by Thermo Fisher for USD 2.6 Billion

Thermo Fisher Scientific Inc. (Waltham, MA; USA) has entered into a definitive agreement to acquire The Binding Site Group (Birmingham, UK) in an all-cash transaction valued at USD 2.6 billion.... Read more

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