Daily clinical lab news - Labmedica.com

Featured Whitepaper

more whitepapers

RANDOX LABORATORIES:
TOTAL BILE ACIDS Download Whitepaper

Download Mobile App

Featured Video

SIGMA ALDRICH CORP.:
Milli Q Connect – Millipore Sigma

View Video

Events

more events

24 Sep 2019 - 26 Sep 2019

Analitica Latin America 2019

24 Sep 2019 - 26 Sep 2019

MEDLAB East Africa.

25 Sep 2019 - 27 Sep 2019

ExpoMedical 2019

Recommended on TradeMed

visit trademed.com

Chemistry Analyzer
respons 910

Immunochromatographic Reader
EASY READER+

Blood Gas Analyzer
Stat Profile Prime

Partner Sites

HospiMedica

Early Surgical Intervention Suggested for Epilepsy Sufferers

Electrical-First Strategy for AF Results in Shorter Hospitalization

Video-Assisted Lung Surgery Reduces Complications

Novel Breathalyzer Can Detect Marijuana Use

Surgical Procedures Best Sclerotherapy for Varicose Veins

New QC Reagents Compatible with Multiple Immunoassay Platforms

Image: The new Acusera quality control reagents are designed for cost-effectiveness, as well as accurate and reproducible results (Photo courtesy of Randox).

A new set of infectious disease (serology) quality control reagents is designed to deliver a cost-effective, high-quality solution for the analysis of infectious diseases, while producing repeatable trustworthy results on various immunoassay platforms.
Read more
22 Sep 2019

Advertisement
Your Lab’s Automated Library Preparation Solution for Next Generation Sequencing eSeminar. Register for Webinar.

AGILENT

Mutation Found Determines Nature of Host Response to MRSA Infection

22 Sep 2019

Breath Analysis Identifies Cancer Patients Likely to Benefit from Immunotherapy

22 Sep 2019

Unusual Sugar Facilitates Long-Term Survival of Leishmania Parasites

22 Sep 2019

Advertisement Beckman Coulter Early Sepsis Indicator
With the potential to revolutionize emergency department sepsis identification, the Early Sepsis Indicator is a new hematological biomarker helping physicians more confidently assess sepsis or the risk of sepsis in adult patients.

BECKMAN COULTER, INC.

Distinctive mRNA Signatures May Prove Diagnostic for Cancer-Related AIS

22 Sep 2019

Differences in Gut Bacteria May Predispose to Heart Attacks

19 Sep 2019

Industry Spotlight

In Other News

$Image: A melanoma on a patient\'s skin. Most melanomas are black or brown, but they may also be skin-colored, pink, red or purple. People with chronic lymphocytic leukemia are at a higher risk for melanomas (Photo courtesy of the National Cancer Institute).$

Chronic Lymphocytic Leukemia Linked with Higher Melanoma Risk

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Read more
19 Sep 2019 | Hematology

Image: The MagPlex Multiplexing Microspheres (Photo courtesy of Luminex).

Multiplex Microsphere Immunoassay Identifies Three Flavivirus Infections

The explosive spread of Zika virus (ZIKV) and associated complications in flavivirus-endemic regions underscore the need for sensitive and specific serodiagnostic tests to distinguish ZIKV, dengue virus (DENV) and other flavivirus infections. Read more
19 Sep 2019 | Microbiology

Image: Nuclear magnetic resonance (NMR) spectroscopy estimated higher HDL-CEC is associated with a lower risk of coronary heart disease (CHD) (Photo courtesy of the University of Oulu).

New Method May Lower Costs Associated with HDL-CEC Measurements

Circulating high-density lipoprotein (HDL) particles mediate reverse cholesterol transport by carrying excess cholesterol from the periphery, such as the arterial wall, to the liver for excretion into the bile. Read more
18 Sep 2019 | Clinical Chemistry

Image: The TripleTOF 6600 Quadrupole Time-Of-Flight (QTOF) mass analyzer (Photo courtesy of Sciex).

Protein Panel Developed for Early Detection of Lung Cancer

Lung cancer is the most common cause of cancer-related mortality worldwide, characterized by late clinical presentation as 49%–53% of patients are diagnosed at stage IV, and consequently have poor outcomes. Read more
18 Sep 2019 | Pathology

Image: The multigene germline panel test prospectively searches for pathogenic or likely pathogenic variants in 30 genes (Photo courtesy of Color Genomics).

Pathogenic Germline Variants Found in Breast Cancer Patients

There is still considerable debate on the value of multigene panel testing for inherited cancer in patients with breast cancer, based on both the prevalence of pathogenic/likely pathogenic (P/LP) variants and any therapeutic implications from genetic test results. Read more
18 Sep 2019 | Molecular Diagnostics

Image: Islet of Langerhans from the pancreas of a patient with chronic Type 1 diabetes of 19 years duration. A single lobe of the pancreas was found to contain islets rich in residual beta cells (alpha cells in red; beta cells in green) (Photo courtesy of Diapedia).

Biomarker Identified for Early Beta-Cell Death in Type 1 Diabetes

Beta cells in the pancreas produce insulin and their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. Read more
18 Sep 2019 | Clinical Chemistry

$Image: This infographic illustrates the connection between the brain, central nervous system and other organs and how they interact with a person\'s gut microbes to show different patterns from people with high blood pressure plus depression; high blood pressure without depression; depression with healthy blood pressure; or healthy subjects without depression or high blood pressure (Photo courtesy of Professor Bruce R. Stevens, PhD).$

Gut Bacteria Linked to High Blood Pressure and Depression

The microbiome is the genetic material of all the microbes, bacteria, fungi, protozoa and viruses that live on and inside the human body. Read more
17 Sep 2019 | Microbiology

Image: Lipid-laden macrophages found in patients with vaping-related respiratory illness. Oily lipids are stained red (Photo courtesy of Andrew Hansen, MD, Jordan Valley Medical Center).

Vaping Illness Characterized by Lipid-Laden Cells in Lungs

Lung scans from patients with vaping illness look like a serious viral or bacterial pneumonia, but those tests come back negative. Read more
17 Sep 2019 | Pathology

Image: The High Mobility Group Box protein 1 (HMGB1) quantitative enzyme-linked immunosorbent assay kit (Photo courtesy of Shino-Test Corporation).

Serum HMGB1 Levels Reflect Clinical Features of HLH

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome. Hypercytokinemia secreted from dysregulated hyperactivated monocytes, macrophages, T cells and NK cells has been reported to play a major role in HLH. Read more
17 Sep 2019 | Hematology

Image: The Parsortix system for collection of circulating tumor cells (Photo courtesy of ANGLE plc).

Automated Collection of CTCs Improves Prostate Cancer Diagnosis

A recent paper described the benefits of circulating tumor cell (CTC) analysis for improving the diagnosis of aggressive prostate cancer beyond currently used PSA (prostate specific antigen) measurement, biopsy and/or MRI imagery. Read more
16 Sep 2019 | Molecular Diagnostics

Image: Zika virus particles (red) shown in African green monkey kidney cells (Photo courtesy of the [U.S.] National Institute of Allergy and Infectious Diseases).

Zika Virus Test Kit Receives American Marketing Approval

A blood test designed to confirm diagnosis of Zika virus infection has been granted 510(k) marketing approval that allows it to be sold in the United States. Read more
16 Sep 2019 | Molecular Diagnostics

Image: G-protein-coupled receptor mechanism (Photo courtesy of Wikimedia Commons).

Autoimmune Antibody Identified as Biomarker for Tachycardia Syndrome

Results published in a recent paper suggested that postural orthostatic tachycardia syndrome (POTS) was probably an autoimmune disorder and may boost the development of a simple blood test to diagnose the condition. Read more
16 Sep 2019 | Molecular Diagnostics

Channels

Clinical Chemistry

view channel

Increased Risk of Hypoandrogenemia Found in Obese Young Men

Hyperandrogenism is a medical condition characterized by high levels of androgens in females, but men with obesity may be at increased risk for developing hypoandrogenemia or low free testosterone, especially... Read more

Image: The i-STAT Alinity system integrates with-patient testing directly into the patient-care pathway, accelerating time to treatment, improving quality and increasing access to care (Photo courtesy of Abbott).

New Blood Test Helps Detect Brain Injury in Minutes

After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic protein (GFAP) correlates with intracranial injury visible on computerized axial tomography (CT) scan.... Read more

Image: A new study suggests patients with gout are at elevated risk for chronic kidney disease (Photo courtesy of Shutterstock).

Gout Increases Risk of Advanced Chronic Kidney Disease

Chronic kidney disease (CKD) is a major public health epidemic, with at least 1 in 10 individuals having some degree of kidney impairment, contributing substantially to adverse clinical and economic outcomes.... Read more

Image: A major new study on the association between blood glucose levels, including HbA1c, and risks of organ impairment in people with type 1 diabetes can make a vital contribution to diabetes care (Photo courtesy of HealthEngine).

Blood Sugar Levels Affect Risks in Type 1 Diabetes

Type 1 diabetes is the predominant form of diabetes diagnosed in childhood and is characterized by increased blood glucose levels resulting from insulin deficiency. Intensive treatment with better glycemic... Read more

Molecular Diagnostics

view channel

Image: The Vanadis Core Cell-Free DNA analysis unit (Photo courtesy of PerkinElmer).

Novel Cell‐Free DNA Screening Assay Validated for Trisomies

Prenatal screening for trisomies 21, 18, and 13 is currently performed using multiple maternal serum and ultrasound markers. Clinical implementation studies of maternal plasma cell‐free (cf)-DNA testing... Read more

Image: By measuring the methylation rate of microRNA, various cancer states can be detected (Photo courtesy of Osaka University).

Methylated MicroRNAs Prove Biomarkers for Early Detection of Cancer

A team of Japanese cancer researchers has shown that microRNA methylation was a more powerful indicator of early-stage pancreatic cancer than were established biomarkers, such as unmodified microRNAs.... Read more

Image: A micrograph showing a mycosis (aspergillosis). The Aspergillus (which is spaghetti-like) is seen in the center and surrounded by inflammatory cells and necrotic debris (Photo courtesy of Wikimedia Commons).

New Official Guideline Summarizes Advances in Fungal Infections Diagnosis

An official clinical guideline on laboratory diagnosis of fungal infections in pulmonary and critical care medicine was released in a recent publication. Timely diagnosis of fungal infections, which... Read more

Image: The top and front view of the three-dimensional structure of the pentameric nicotinic acetylcholine receptor, which is damaged or destroyed in myasthenia gravis (Photo courtesy of Wikimedia Commons).

Metabolites Pattern Distinguishes Myasthenia Gravis from RA Patients

A team of Canadian researchers used a pattern of 12 metabolites to distinguish myasthenia gravis patients from healthy individuals or from those with rheumatoid arthritis. Myasthenia gravis (MG) is... Read more

Hematology

view channel

Image: Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia (Photo courtesy of Paris-Saclay University).

Genetics Affect Risk of Developing Factor VIII Inhibitors

For severe hemophilia A (HA) patients, the current standard of care includes regular prophylactic infusions of factor VIII (FVIII) products in order to prevent spontaneous bleeds or on demand infusions... Read more

Image: The Ortho ProVue automated blood bank analyzer (Photo courtesy of Ortho Clinical Diagnostics).

Clinical Specificity of RBC Alloantibodies Studied in Pregnant Women

Maternal red cell immunoglobulin G (IgG) antibodies can cross the placenta and cause hemolysis of fetal red cells in case of antigenic differences between maternal and fetal red blood cells (RBCs), leading... Read more

Image: A peripheral blood smear from a patient with iron deficiency anemia: significant hypochromia and microcytosis is seen, as well as moderate variation in size and shape of the red cells (Photo courtesy of American Society of Hematology).

Toolkit Developed for Iron Deficiency in Pregnancy

The risk of iron deficiency (ID) increases during pregnancy due to an increase in maternal iron requirements to accommodate the expansion of maternal red blood cell (RBC) mass, development of the placenta... Read more

Image: The BC-5800 hematology autoanalyzer (Photo courtesy of Mindray).

Platelet Volume Related to Geriatric Patient In-Hospital Mortality

Treatment of acute coronary syndrome involves inhibition of platelet activity and thrombus formation. Platelets play a significant part during myocardial infarction by enhancing microvascular obstruction... Read more

Immunology

view channel

Image: A photomicrograph of an immunofluorescence assay (IFA) for Rickettsia (Photo courtesy of Fuller Laboratories).

Immunoassays Compared for Diagnosis of Acute Murine Typhus Infections

Murine typhus is a disease transmitted by fleas and is caused by intracellular gram-negative bacteria called Rickettsia typhi, and manifested clinically with acute fever, chills, muscle pain, nausea, vomiting,... Read more

Image: NETosis Assay Kit: PMA induces neutrophil extracellular trap (NET) formation in human neutrophils (Photo courtesy of Cayman Chemical).

Differential Immune Responses Triggered against Salmonella enterica

Enteric fevers, caused by the Salmonella enterica serovars Typhi (ST), Paratyphi A (PA) and Paratyphi B (PB), are life-threatening illnesses exhibiting very similar clinical symptoms but with distinct... Read more

Image: Aspergillus (Photo courtesy of Kateryna Kon / Fotolia.com).

Novel ELISA Detects Invasive Aspergillosis

Aspergillus spp. is a ubiquitous sac fungus, which is found in soil or compost or on damp walls. Inhalation of spores can lead to severe infections in individuals with a weakened immune system.... Read more

Image: The CFX96 Touch RT-PCR detection system (Photo courtesy of Bio-Rad Laboratories).

Enterovirus Antibodies Detected in Acute Flaccid Myelitis Patients

Neurotropic enteroviruses (EVs), such as poliovirus, have long been associated with paralytic disease. Acute flaccid myelitis (AFM) has caused motor paralysis in more than 560 children in the United States... Read more

Microbiology

view channel

Human Intestinal Enteroids Used to Detect Norovirus Infectivity

Human norovirus accounts for 18% of acute gastroenteritis cases worldwide. Molecular nucleic acid tests, such as real-time reverse transcription polymerase chain reaction (rRT-PCR), are widely used for... Read more

Image: A photomicrograph showing Trypanosoma brucei gambiense in a blood film. This parasitic protozoan species causes African trypanosomiasis (or sleeping sickness) in humans via the tsetse fly (Photo courtesy Alain G.C. Buguet).

Detergent-Enhanced LAMP Detects African Trypanosome in CSF

Human African trypanosomiasis is a fatal disease, if untreated, spread by bloodsucking tsetse flies. These protozoan parasites first enter the lymph and blood to invade many organ systems, the early stage... Read more

Image: Drumstick-shaped Clostridioides difficile bacilli as they appear in scanning electron microscopy (Photo courtesy of Kateryna Kon, PhD).

Fungus-Associated Bacteriome Associated with C. difficile Infection

Clostridioides difficile infection (CDI), the most common etiology of nosocomial infectious diarrhea, is caused by an intestinal dysbiosis that is virtually always attributable to antibiotics.... Read more

Image: A collection of whole saliva by the Salivette (absorbent) method. (a) Saliva is collected by chewing a cotton wool swab. (b) The swab containing saliva is placed in the tube of Salivette. (c) Centrifugation of the assemblage. (d) Saliva is separated from the swab and is ready for analysis (Photo courtesy of Sarstedt).

Optimized Immunoassays Detect HBV in Oral Fluid Samples

It is estimated that there are 257 million chronic hepatitis B (HBV) carriers worldwide, which highlights the substantial health, social, and economic burden of HBV. Screening of infected, cured and vaccinated... Read more

Pathology

view channel

CTC Purification Enables Identification of Cancer-Linked Genetic Arrangements

The use of circulating tumor cells (CTCs) as a surrogate tumor source for molecular profiling of disease offers a potential noninvasive diagnostic solution for understanding underlying tumor biology, guiding... Read more

Image: A new study showed men with diabetes had a higher blood testosterone level than non-diabetic men (Photo courtesy of Diamed Diagnostical Center).

Hormone Levels of Diabetic Men Not Related to Prostate Cancer Risk

Diabetes mellitus (DM) is a group of metabolic disorders characterized by high blood sugar levels over a prolonged period and is conventionally associated with an increased risk of cancer; however, inverse... Read more

Image: A circulating tumor cell (arrow) diagnosed by the isolation by size of epithelial tumor cells (ISET) test (The pores of the filter are also visible) (Photo courtesy of Chichiselector).

Circulating Tumor Cells Directly Detected in Blood Samples

Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity. Scientists have now introduced... Read more

Image: The NextSeq 500 next-generation sequencer (Photo courtesy of Illumina).

Combination of Gene Mutations Linked to Endometrial Cancer

The endometrium is the dynamic inner layer of the uterus, composed of stroma and epithelial cells that undergo monthly proliferation, differentiation, and shedding throughout the menstrual cycle in reproductive... Read more

Lab Tech.

view channel

Image: An MIT-invented microfluidics device could help doctors diagnose sepsis, a leading cause of death in US hospitals, by automatically detecting elevated levels of a sepsis biomarker in about 25 minutes, using less than a fingerprick of blood (Photo courtesy of Felice Frankel).

Microfluidic Device Rapidly Diagnoses Sepsis

Sepsis is a life-threatening condition and early diagnosis is crucial to ensure that treatment is not delayed. However, as current diagnostic methods are imprecise, the condition is misdiagnosed in 30% of patients.... Read more

Image: A new study suggests that cutting-edge electronic devices can help doctors diagnose early stage bladder cancer (Photo courtesy of Ana Sandoiu).

Electronic Device May Help Diagnose Early Bladder Cancer

It is estimated that bladder cancer will affect 80,470 people in the USA this year, and about 17,670 deaths are likely to result from these cases. Doctors diagnose approximately half of all bladder cancers... Read more

New Systems Offer Cost-Effective Urinalysis at Any Lab Scale

With the growing prevalence of kidney-related diseases, proper screening and detection have become an increasing priority for clinicians. Two newly introduced systems, LAURA and LAURA XL, now aim to fill... Read more

Image: (A and B) Photomicrographs of the layers of the device; (C) the mold ready for casting and (D) the chip mounted on a slide (Photo courtesy of San Diego State University).

Microfluidic Device Isolates Circulating Tumor Cell Clusters

The three main challenges of cancer treatment are metastases, recurrence, and acquired therapy resistance. These challenges have been closely linked to circulating cancer cell clusters. About 90% of... Read more

BioResearch

view channel

$Image: Circulating tumor cell-free DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized (Photo courtesy of Wikimedia Commons).$

Click for LinkXpress Reader Inquiry Service
Enter code to receive information:

Where I can find code?

LinkXpress

Featured Products

Featured Whitepaper

Download Mobile App

Trending Articles

Featured Video

Events

Recommended on TradeMed

Partner Sites

HospiMedica

Industry Spotlight

In Other News

Channels

LabMedica

Channels

Features

Partner Sites