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Events

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
24 Apr 2021 - 29 Apr 2021
Virtual Venue
EAHP-SH 2021 – 20th Meeting of the European Association for Haematopathology
26 Apr 2021 - 30 Apr 2021
Virtual Venue
FOCUS 2021 – National Meeting (UK) of the Association for Clinical Biochemistry & Laboratory Medicine (ACB).
04 May 2021 - 07 May 2021
Virtual Venue
ISLH 2021 – International Society of Laboratory Hematology
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Image: Mindray Analyzers Help Detect Hematological Parameters to Support COVID-19 Diagnosis and Prognosis (Photo courtesy of Mindray)

Mindray Analyzers Help Detect Hematological Parameters to Support COVID-19 Diagnosis and Prognosis

Mindray (Shenzhen, China) hematology analyzers are using advanced technologies to detect inflammatory parameters, such as white blood cell count (WBC), neutrophil count, neutrophil-to-lymphocyte ratio (NLR) and red blood cells (RBC) that can support COVID-19 diagnosis and prognosis. Read more
19 Apr 2021 | COVID-19
Image: Qorvo Omnia SARS-CoV-2 Antigen Test (Photo courtesy of Qorvo Biotechnologies, LLC)

Portable COVID-19 Test Instrument Uses Bulk Acoustic Wave Technology to Achieve SARS-CoV-2 Antigen Testing in 20 Minutes

A new COVID-19 test platform represents a paradigm shift in diagnostic testing capability by using high frequency Bulk Acoustic Wave (BAW) sensors to achieve SARS-CoV-2 antigen testing in approximately 20 minutes. Read more
19 Apr 2021 | COVID-19
Image: The Phadia 200 instrument is small enough to fit on a benchtop, and yet capable of running the complete menu of more than 700 different ImmunoCAP and EliA tests to aid in the diagnosis of allergy and autoimmune diseases (Photo courtesy of Thermo Fisher Scientific)

Circulating Calprotectin as Biomarker in Neutrophil-Related Inflammation

Calprotectin (CLP) acts as an endogenous ligand of different cell-surface proteins like Toll-like receptor 4 and receptor of advanced glycation end-products facilitating a local proinflammatory effect. Read more
15 Apr 2021 | Clinical Chem.
Image: The LUCIRA CHECK IT test kit (Photo courtesy of Lucira Health, Inc.)

First-Ever Single-Use, PCR Quality OTC COVID-19 At-Home Test Granted FDA EUA

The US Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) for the first-ever single use, over the counter (OTC) sale of a COVID-19 test kit that delivers PCR quality molecular accuracy in 30 minutes or less at home. Read more
15 Apr 2021 | COVID-19
Image: AnteoTech’s EuGeni Reader and in vitro rapid diagnostic test (Photo courtesy of AnteoTech Ltd.)

Nanoparticle Technology Based Digital Reader Supports High-Sensitivity, High-Specificity Rapid COVID-19 Testing

A new 15-minute COVID-19 antigen rapid test (ART) for a nanoparticle technology-based rapid test platform has received the Conformitè Europëenne (CE) Mark registration. Read more
15 Apr 2021 | COVID-19
Image: Inflammation of the pancreatic islets with mononuclear cells including T-cells is the hallmark of Type 1 diabetes (Photo courtesy A. van Halteren)

Type 1 Diabetes Onset Preceded by Gene Expression Changes

Type 1 diabetes (T1D) results from insufficient insulin production and is thought to result from an immune reaction against the body’s own pancreatic β cells. Read more
14 Apr 2021 | Immunology
Image: Histology comparison of airway features in (A) a healthy individual and (B) in a patient with chronic obstructive pulmonary disease where airways are narrowed by infiltration of inflammatory cells, mucosal hyperplasia, and deposition of connective tissue in the peribronchiolar space (Photo courtesy of University of Leuven)

Coagulation Dysfunction and Infection Evaluated in Patients with AECOPD

Chronic obstructive pulmonary disease (COPD) is one of the common chronic airway obstructive diseases, characterized by persistent respiratory symptoms and airflow limitation. Read more
14 Apr 2021 | Hematology
Illustration

Ortho's VITROS SARS-CoV-2 Antigen Test for High-Volume COVID-19 Testing Receives CE Mark

Ortho Clinical Diagnostics (Raritan, NJ, USA) has received CE Marking for its VITROS SARS-CoV-2 Antigen Test, allowing for more convenient sample collection and expanded viral transport media. Read more
14 Apr 2021 | COVID-19
Image: Diagnostic Microchip Inserted Under Skin Can Detect COVID-19 (Photo courtesy of DARPA)

Diagnostic Microchip Inserted Under Skin Can Detect COVID-19

Researchers have created a microchip that can detect COVID-19 when inserted under the skin.

The implantable microchip developed by medical researchers at the US Pentagon’s Defense Advanced Research Projects Agency (DARPA; Arlington, VA, USA) can monitor the human body for signs of the SARS-CoV-2 virus. Read more
14 Apr 2021 | COVID-19
Image: The Hyperion Imaging System brings proven CyTOF technology together with imaging capability to empower simultaneous interrogation of four to 37 protein markers using Imaging Mass Cytometry (Photo courtesy of Fluidigm)

Spatial Landscape of Lung Pathology Investigated During COVID-19 Progression

Early histopathological changes of viral pneumonias are rarely observed because histopathological examination is not necessary for diagnosis, but late stage changes in viral pneumonias are well defined, most commonly in autopsy series. Read more
13 Apr 2021 | Pathology
Image: Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis (Photo courtesy of Dr. Christopher Wiley)

Novel Lipid Biomarker Detects Senescent Cells

A recent paper identified a lipid biomarker indicative of cellular senescence and described a method to evaluate its effect on the molecular events that lead to senescence. Read more
13 Apr 2021 | Molecular Diagnostics
Image: Philips Digital Pathology (Photo courtesy of Royal Philips)

Philips Collaborates with AI Startup Ibex to Accelerate Adoption of AI-Powered Digital Pathology Solutions

Royal Philips (Amsterdam, The Netherlands) and Ibex Medical Analytics (Tel Aviv, Israel) have entered into a strategic collaboration to jointly promote their digital pathology and AI solutions to hospitals, health networks and pathology labs worldwide. Read more
13 Apr 2021 | Industry
Illustration

Thermo Fisher’s New High-Throughput, Automated System for Leading COVID-19 Test Granted FDA EUA

Thermo Fisher Scientific Inc. (Waltham, MA, USA) has been granted Emergency Use Authorization (EUA) by the U. Read more
13 Apr 2021 | COVID-19

Channels

Clinical Chem.

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Vitamin D Levels Tied to COVID-19 Risk for African-Americans
Calcitonin and Procalcitonin Immunoassays Investigated for Medullary Thyroid Car...
Chemiluminescence Anti‐Müllerian Hormone Assay Performance Characterized
Image: Elevated liver enzymes are associated with incident diabetes in US Hispanic/Latino adults (Photo courtesy of Judy George, BA, MBA)

High Liver Enzymes Increase Diabetes Risk for Hispanic Adults

Non‐alcoholic fatty liver disease (NAFLD) has been associated with increased risk of incident diabetes, but such evidence is lacking in the Hispanic/Latino population, which has high prevalence of obesity and NAFLD.... Read more

Molecular Diagnostics

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A Protein Biomarker Aids Cancer Patients by Controlling the Dosage of Highly Toxic...
Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal ...
Advances in High-Tech Methods for Cervical Cancer Screening
Image: The EZ DNA Methylation-Direct Kit (Photo courtesy of Zymo Research)

Leukocyte Epigenomics and Artificial Intelligence Predict Late-Onset Alzheimer’s Disease

Alzheimer’s Disease (AD) is the most common form of age-related dementia, accounting for 60%–80% of such cases. The disorder causes a wide range of significant mental and physical disabilities, with profound... Read more

Hematology

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Flow-Cytometric Expression of Endoglin Assessed in B-Acute Lymphoblastic Leukemi...
Clonal Hematopoiesis and Recurrent Mutations Identified in Blood Cancers
COVID-19 Induces a Hyperactive Phenotype in Circulating Platelets
Image: The BD FACSAria III sorter is equipped with five lasers, 17 fluorescence channels and two channels for Forward Scatter and Side Scatter (Photo courtesy of BD Biosciences)

Genome Sequencing Identifies Myeloma Precursor Disease with Progression Risk

Multiple myeloma (MM) is the second most common hematological malignancy and is consistently preceded by the asymptomatic expansion of clonal plasma cells, termed either monoclonal gammopathy of undetermined... Read more

Immunology

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Immunoassay Developed for Quantitative Detection of Serum Interleukin‐6
Performance of Five Lipoprotein(a) Immunoassays Evaluated
Toxoplasmosis Immune Status in Pregnancy Determined by Immunochromatography Assa...
Image: Besides the typical periglomerular localization, a diffuse interstitial leukocyte infiltration is very common in ANCA-associated vasculitis (Photo courtesy of Dr. Franco Ferrario and Dr. Maria Pia Rastaldi)

Serious Infections Prevalent in ANCA-Associated Vasculitis

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are among the rheumatic diseases with the highest mortality and morbidity, due to their major multi-organ involvement (lungs, kidneys)... Read more

Microbiology

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Toxoplasmic Encephalitis in HIV Patients Detected in Urine
Whipple’s Disease Pathogen Found in International Diarrhea Patients
Magneto-Optical Diagnosis Evaluated for Symptomatic Malaria
Image: White blood cells in the urine of a patient with bacteriuria pyuria, a urinary tract infection. The cells have lobed nuclei and refractile cytoplasmic granules (Photo courtesy of University of Utah Medical School).

White Blood Cell Help Define Pediatric Urinary Tract Infections

Urinary tract infections account for up to 7% of fevers in children up to 24 months old and are a common driver of hospital emergency room visits. These bacterial infections in infants and toddlers can... Read more

Pathology

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Blood Biomarker Predicts Dementia in Cerebral Small Vessel Disease
Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Blood Test Detects Early Colorectal Adenomas
Image: High-power photomicrograph of ductal adenocarcinoma (Prostate cancer) illustrating tall columnar cells with pale to clear cytoplasm and large ovoid nuclei (Photo courtesy of David J. Grignon, MD).

22-Gene Genomic Classifier Validated in Recurrent Prostate Cancer Patients

When prostate cancer has been detected or has returned following initial treatment with surgery, radiation therapy and/or hormone therapy, it is said to be recurrent or relapsed. Treatment of recurrent... Read more

Technology

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Epidermal Patch Simultaneously Monitors Hemodynamic and Metabolic Biomarkers
Biosensing Microneedle Patch Quantifies Biomarkers in Interstitial Fluid
Lab-on-a-Chip Infection Test Provides Cheaper, Faster Portable Diagnostics
Image: The Vantera Clinical Analyzer based on nuclear magnetic resonance (Photo courtesy of Liposcience)

NMR-Based Method Measures Circulating Blood Citrate Levels

Recent studies show that citrate is involved in several biological processes such as inflammation, cancer, insulin secretion, acetylation of histones, neurological development and hydroxylglutaric aciduria,... Read more

BioResearch

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Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma
New Method Simplifies Preparation of Tumor Genomic DNA Libraries
New Tool Developed for Diagnosis of Chronic HBV Infection
Structure of the RGS1 protein (Photo courtesy of Wikimedia Commons)

Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

A genomics-based blood test can predict likelihood that a baby suffering hypoxia at birth will suffer serious nervous disorders such as cerebral palsy or epilepsy at a later stage of development.... Read more

Industry

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PerkinElmer’s EUROIMMUN Launches Novel Ultrafast Automated Microscope and Intell...
Roche to Acquire Genmark Diagnostics to Access Novel Technology to Test for Path...
EKF Globally Launches STAT-Site WB β-Ketone and Glucose Handheld Analyzer
Image: The Novodiag platform combines real-time PCR and microarray capabilities to provide high-level multiplexing (Photo courtesy of Mobidiag Ltd.)

Hologic to Acquire Mobidiag to Strengthen Diagnostic Testing Business

Hologic, Inc. (Marlborough, MA, USA) has signed a definitive agreement to acquire Mobidiag Ltd. (Espoo, Finland) in a USD 795 million transaction that will accelerate the global growth of Mobidiag’s differentiated... Read more

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