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Events

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
01 Dec 2020 - 04 Dec 2020
Virtual Venue
6th Annual Conference of the Saudi Society for Clinical Chemistry (SSCC)
05 Dec 2020 - 08 Dec 2020
Virtual Venue
62 Annual Meeting & Exposition of the American Society of Hematology (ASH)
06 Dec 2020 - 08 Dec 2020
Virtual Venue
32nd Congress of the European Society of Pathology (ESP).

In Other News

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FDA Grants EUA to One of the First Tests That Measures Specific Levels of COVID-19 Neutralizing Antibodies

The US Food and Drug Administration (FDA) has granted Emergency Use Authorization (EUA) to one of the first tests that measures specific levels of COVID-19 neutralizing antibodies. Read more
26 Nov 2020 | COVID-19
Image: ESPLINE SARS-CoV-2 lateral flow antigen test (Photo courtesy of Mast Group Ltd.)

Mast Group Launches New ESPLINE SARS-CoV-2 Lateral Flow Antigen Test

Mast Group Ltd. (Liverpool, UK) has launched the new ESPLINE SARS-CoV-2 lateral flow antigen test for the detection of COVID-19. Read more
26 Nov 2020 | COVID-19
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Beckman Coulter Launches Semi-Quantitative Access SARS-CoV-2 IgG II Antibody Test

Beckman Coulter Diagnostics (Brea, CA, USA) has launched its Access SARS-CoV-2 IgG II assay that measures a patient’s relative level of antibodies in response to a previous SARS-CoV-2 infection. Read more
26 Nov 2020 | COVID-19
Image: Xpert Xpress SARS-CoV-2, Flu A, Flu B and RSV Combination Test (Photo courtesy of Cepheid)

Cepheid Receives CE-IVD Registration for SARS-CoV-2, Flu A, Flu B and RSV Combination Test

Cepheid (Sunnyvale, CA, USA) has received the CE-IVD marking for its Xpert Xpress SARS-CoV-2/Flu/RSV, a rapid molecular diagnostic test for qualitative detection of the viruses causing COVID-19, Flu A, Flu B, and RSV infections from a single patient sample. Read more
25 Nov 2020 | COVID-19
Image: Micrograph showing fibrosis of the liver caused by cirrhosis. The tissue in this example is stained with a trichrome stain, in which fibrosis is colored blue. The red areas are the nodular liver tissue (Photo courtesy of Wikimedia Commons)

Panel of Urinary Peptides Used to Diagnose Liver Fibrosis

A panel of 50 urinary peptides was shown to be a useful tool for the early diagnosis of liver fibrosis. Read more
24 Nov 2020 | Molecular Diagnostics
Image: The portable MinION sequencing platform runs one flow cell and desktop GridION can run up to five flow cells at any time (Photo courtesy of Oxford Nanopore).

Metagenomic Sequencing Quickly Identifies Pathogens in Body Fluids

Metagenomic next-generation sequencing (mNGS) is a shotgun sequencing approach in which all of the nucleic acid (DNA and RNA) in a clinical sample is sequenced at a very high depth, 10-20 million sequences per sample. Read more
23 Nov 2020 | Microbiology
Image: A clot in the neck or brain can lead to a stroke (Photo courtesy of Mayo Clinic)

Blood Biomarker Protein Correlates with Severity of Brain Damage in Stroke Patients

Researchers have identified a stroke-related biomarker protein that correlates with the severity of brain tissue damage as well as with functional outcome and mortality. Read more
23 Nov 2020 | Molecular Diagnostics
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Ortho's CE-Marked VITROS SARS-CoV-2 Antigen Test Detects Asymptomatic COVID-19 Individuals

Ortho Clinical Diagnostics (Raritan, NJ, USA) has announced that its CE-marked VITROS SARS-CoV-2 antigen test can now detect SARS-CoV-2 infection in asymptomatic individuals. Read more
23 Nov 2020 | COVID-19
Illustration

First Hybridization Capture-Based NGS Assay for Characterization and Surveillance of SARS-CoV-2 Launched

The launch of the first-ever hybridization capture-based next-generation sequencing (NGS) SARS-CoV-2 assay for characterization and surveillance of the virus could provide an important new research tool for the sequencing and surveillance of COVID-19. Read more
20 Nov 2020 | COVID-19
Image: Histological features of COVID-19 lungs (Photo courtesy of the University of Trieste).

COVID-19 Lung Damage Caused by Persistence of Abnormal Cells

Several uncertainties still relate to the involvement of other organs in COVID-19. Besides indirect multi-organ injury, a few reports have suggested the possibility of direct injury caused by viral replication in brain, heart and kidney. Read more
19 Nov 2020 | Pathology
Image: The QTRAP 6500+ Liquid Chromatography with tandem mass spectrometry system (Photo courtesy of Sciex).

Biomarkers Predict Whether RA Patients Will Respond to DMARDs

Rheumatoid arthritis (RA) is characterized by unremitting joint inflammation that results in bone and cartilage destruction and a decreased quality of life. Read more
19 Nov 2020 | Clinical Chemistry
Image: Lucira COVID-19 All-In-One Test Kit (Photo courtesy of Lucira Health, Inc.)

FDA Authorizes First COVID-19 Test for Self-Testing at Home

The US Food and Drug Administration (FDA) has authorized the first prescription molecular diagnostic test for COVID-19 that can be performed entirely at home. Read more
19 Nov 2020 | COVID-19

Channels

Clinical Chemistry

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Metabolomics Profiles Associated with Diabetic Retinopathy
High-Sensitivity C-Reactive Protein Investigated in Acute Myocardial Infarction ...
Novel Fecal Calprotectin Test Validated in Pediatric Population
Image: The Ammonia Breath test: the sensing system included a desiccation cylinder, an airtight sensing chamber, a rotameter, a pump, and an electrical signal measurement instrument (Photo courtesy of Chang Gung University).

Breath Ammonia Biomarker Predicts Kidney Function in CKD Patients

Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months to years. Initially there are generally no symptoms; later, symptoms may... Read more

Molecular Diagnostics

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Methylated DNA Profiling Explored for Prenatal Testing Applications
CRP Tracking Predicts Potential Outcome for Hospitalized COVID-19 Patients
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
Image: Levels of MicroRNAs in Saliva Are Diagnostic for Mild Traumatic Brain Injury (Photo courtesy of iStock/JuSun)

Levels of MicroRNAs in Saliva Are Diagnostic for Mild Traumatic Brain Injury

Measurement of levels of microRNAs in saliva was used to diagnose the presence of concussion (mild traumatic brain injury or mTBI) in a group of patients suffering from head trauma. Mild traumatic brain... Read more

Hematology

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Paper Diagnostic Directly Measures Fibrinogen in Whole Blood
Newborns Getting Preoperative Blood Transfusions Have More Complications
New Technology Rapidly Diagnoses Sickle Cell Disease
Image: The 5200 Fragment Analyzer system performs DNA QC and RNA QC for a broad range of samples including, gDNA, small RNA, cfDNA, large DNA fragments, and total RNA (Photo courtesy of Agilent Technologies).

CD200 Expression Marks Leukemia Stem Cells in Human AML

Acute myeloid leukemia (AML) is organized as a hierarchy sustained by a minor population of leukemia stem cells (LSCs) with self-renewal capacity that drive disease. The LSC populations of AML exhibit... Read more

Immunology

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Serum-IgG Responses in Patients with Mild and Severe COVID-19
Methods for Automated Anti-Neutrophil Cytoplasmic Antibodies Compared
MAIT Cell Activation Dynamics Associated with COVID-19 Disease Severity
Image: Autoantibody order, timing helps predict genetically susceptible children most likely to get type 1 diabetes (Photo courtesy of the Morsani College of Medicine).

Autoantibody Timing Predicts Genetically At-Risk Children for Diabetes

While antibodies are molecules produced by the body's immune system to detect and destroy specific viruses, bacteria and other harmful substances, autoantibodies are antibodies that target a person's own... Read more

Microbiology

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Antibodies Against Rabies Detected in Human Dried Blood Spots
New Diagnostic Tests for Rotavirus and Norovirus Infections Evaluated
Bacterium and Viral Coinfection Contributes to Postinfectious Hydrocephalus
Image: The STANDARD F Dengue IgM/IgG FIA qualitatively analyzes Dengue virus specific IgM and IgG antibodies in serum, plasma and whole blood using fluorescent immunoassay (Photo courtesy of SD Biosensor).

Rapid Tests Evaluated in the Management of Dengue Fever

Dengue is a mosquito-borne infection caused by four distinct viruses (DENV 1-4) which belong to the flavivirus genus and may lead to diverse outcomes. The disease can be asymptomatic in about 75% of cases,... Read more

Pathology

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Fecal Immunochemical Test Assessed in Suspected Colorectal Cancer
Urine-Based Liquid Biopsy Test Detects Urothelial Carcinoma
Lymphocytic Infiltration Explored as Biomarker for Stable Colorectal Tumors
Image: The CELLSEARCH CTC System is the first and only clinically validated, FDA-cleared system for identification, isolation, and enumeration of circulating tumor cells (CTCs) from a simple blood test (Photo courtesy of Menarini Silicon Biosystems).

Circulating Tumor Cell-Count Drives Therapy Choice for Breast Cancer

The choice between chemotherapy and endocrine therapy as first-line treatment for hormone receptor–positive, ERBB2 (also known as HER2)-negative metastatic breast cancer is usually based on the presence... Read more

Technology

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Saliva Test Fast Tracks Heart Attack Diagnosis
Microfluidic Device Explores Ovarian Cancer Interactions
Nanoparticle System Captures Heart-Disease Biomarker From Blood
Image: Cryptosporidium oocysts and the larger Giardia cysts stained by Crypto/Giardia IFA kit (Photo courtesy of Cellabs).

Smartphone Microscopic Method Detects Cryptosporidium and Giardia

Food and water-borne illness arising from the consumption of contaminated food and water are serious health hazards globally. Cryptosporidium and Giardia are the major food and water‒borne parasites.... Read more

BioResearch

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Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma
New Method Simplifies Preparation of Tumor Genomic DNA Libraries
New Tool Developed for Diagnosis of Chronic HBV Infection
Structure of the RGS1 protein (Photo courtesy of Wikimedia Commons)

Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

A genomics-based blood test can predict likelihood that a baby suffering hypoxia at birth will suffer serious nervous disorders such as cerebral palsy or epilepsy at a later stage of development.... Read more

Industry News

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Randox and Bosch Healthcare Alliance Targets COVID-19 Testing
Mindray Hematology Solution Helps High-Volume Lab Run 2,820,000 CBC Tests Annual...
2020 AACC Annual Scientific Meeting & Clinical Lab Expo to Be an All Virtual Event...
Image: Absorbance 96 Plate Reader (Photo courtesy of Enzo Biochem)

Enzo Biochem Launches Portable Microplate Reader for Use with Its ELISA and Assay Kits

Enzo Biochem (New York, NY, USA) has launched a small portable microplate reader for use with the company’s immunoassays and, ultimately, molecular diagnostics, providing new opportunities in point-of-care medicine.... Read more

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