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Trending Articles

Allogeneic Stem Cell Transplants Improve Microbiome, Immune Cells

MRD in AML Detected by Deep Sequencing CD34+ Cells

Serum Vimentin Predicts Mortality in Pediatric Severe Sepsis

QuidelOrtho Formed by Combining Quidel and Ortho

Presepsin Proposed as 'Robust' Biomarker of Early-Onset Sepsis

Novel Microfilarial Antigen Diagnoses Lymphatic Filariasis Infections

Serological Markers of RA Determined in Patients with aβ2GPI-IgA

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Events

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

01 Jul 2022 - 03 Jul 2022

EAACI Hybrid Congress 2022 - European Academy of Allergy & Clinical Immunology

03 Jul 2022 - 06 Jul 2022

ESHRE 2022 – 38th Annual Meeting of the European Society of Human Reproduction and Embryology

24 Jul 2022 - 28 Jul 2022

2022 AACC Annual Scientific Meeting & Clinical Lab Expo

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Chest CT Scans of COVID-19 Patients Could Help Distinguish Between SARS-CoV-2 Variants

Imaging Technology Illuminates Lung Cancer Tumors to Make Surgical Removal Easier

Breakthrough Technology Kills Bacteria Formed on Surface of Medical Implants After Surgery

4D Flow MRI Scans Could Revolutionize Diagnosis of Patients with Heart Failure

Robot-Assisted Surgical Devices Market Driven by Increased Demand for Patient-Specific Surgeries

Maternal Autoantibody Profiles Are Biomarkers for Autism

Image: The Bio-Rad iMark Microplate Absorbance Reader (Photo courtesy of Electronics Depot USA)

Autism is a neurodevelopment condition affecting 1 in 44 children in the U.S. It has a wide range of characteristics with different intensities and causes. One type of autism is maternal autoantibody–related autism spectrum disorder (MAR ASD). Read more
28 Jun 2022

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Microbes Identified In Leukemic Febrile Neutropenia

28 Jun 2022

Electrochemical Sensor Platform to Enable New Diagnostic Tests in Near-Patient Settings

28 Jun 2022

Blood Test to Assess Nerve Damage Could Also Detect Alzheimer’s Years Before Onset

28 Jun 2022

Caspase-6-Cleaved Tau Is Relevant in Alzheimer's Disease

27 Jun 2022

Molecular Tumor Profiling Benefits Pediatric Cancer Patients

27 Jun 2022

Industry Spotlight

Fujirebio Acquires ADx NeuroSciences to Speed Development of Neurodegenerative Diseases Diagnostic Tests

Fujirebio Holdings, Inc. (Tokyo, Japan) has announced the acquisition of ADx NeuroSciences (Gent, Belgium) for EUR 40 million in a deal that is expected to close in July 2022, pending the satisfaction of customary closing conditions. Read more
24 Jun 2022

Medix Biochemica Acquires IVD Raw Materials Producer Bioresource Technology

Medix Biochemica (Espoo, Finland) has acquired 100% of the shares of Bioresource Technology (BRT, Weston, FL, USA) to broaden its base matrix capabilities and further strengthen its local presence in the US market. Read more
21 Jun 2022

BD Partners with Mayo Clinic Platform for Access to World's Largest Collection of Clinical Data

Becton, Dickinson and Company (BD, Franklin Lakes, NJ, USA) has entered into a collaboration with Mayo Clinic Platform (Rochester, MN, USA) to access de-identified patient data from Mayo Clinic Platform_Discover to perform detailed post-market surveillance on its products to fuel innovation and unlock a faster, more efficient path to market, with the ultimate goal of improving patient care. Read more
14 Jun 2022

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In Other News

Image: Cusabio Human Irisin ELISA Kit Predicts Development of Gestational Diabetes (Photo courtesy of American Research Products, Inc.)

Serum Irisin Predicts Development of Gestational Diabetes

Gestational diabetes mellitus (GDM) is a condition in which a hormone made by the placenta prevents the body from using insulin effectively. Read more
27 Jun 2022 | Clinical Chem.

Image: SERS detects presence of chemical indirectly by using laser light and a specialized sensor (Photo courtesy of The University of Tokyo)

Wearable Sensor Detects Viruses Through On-Body Chemical Analysis

Wearable technology is not new. For instance, most smartwatches can monitor certain health parameters such as heart rate, but cannot measure chemical signatures which could be useful for medical diagnosis. Read more
27 Jun 2022 | Technology

Image: The VersaMax ELISA Microplate Reader for visible absorbance measurements between 340 nm and 850 nm (Photo courtesy of Molecular Devices).

Biomarkers of Collagen Turnover Investigated in Crohn’s Disease

Crohn's disease (CD) is a chronic ulcerative inflammatory disease mainly affecting the gastrointestinal (GI) tract and is characterized by an inappropriate and uncontrolled immune response that is putatively triggered by the gut microbiome in genetically susceptible individuals. Read more
24 Jun 2022 | Clinical Chem.

Image: A new method reliably detects protein changes in blood that are typical of Parkinson`s disease (Photo courtesy of Pexels)

First-Ever Blood Test Detects Parkinson’s Disease

Until now, the diagnosis of Parkinson's disease has been based primarily on typical movement disorders such as muscle stiffness, slower movements and shaking. Read more
24 Jun 2022 | Molecular Diagnostics

Image: Automated liquid biopsy test quickly IDs cancer DNA in patients with metastatic breast cancer (Photo courtesy of Johns Hopkins)

Automated Liquid Biopsy Test Detects Advanced Breast Cancer in Five Hours

Many patients with breast cancer do not respond to chemotherapy but go through multiple cycles of treatment before oncology teams can perform imaging studies to determine if a treatment is effective. Read more
24 Jun 2022 | Molecular Diagnostics

Image: The Unyvero LRT Panel for Use with Bronchoalveolar Lavage Specimens (Photo courtesy of Rick Betts)

Pneumonia Panel Helps Curb Inappropriate Antibiotic Usage

Pneumonia is swelling (inflammation) of the tissue in one or both lungs. It's usually caused by a bacterial infection or a virus. Read more
23 Jun 2022 | Microbiology

Image: Colonic biopsy with features of collagenous colitis. Trichrome stain highlights irregular subepithelial collagen with entrapment of capillaries and inflammatory cells (Photo courtesy of Catherine E. Hagen, MD)

Appendectomy Linked to Higher Risk of Microscopic Colitis

The most common symptom of microscopic colitis is chronic, watery, non-bloody diarrhea. Episodes of diarrhea can last for weeks, months, or even years. Read more
23 Jun 2022 | Pathology

Image: Stages of progression of non-alcoholic fatty liver disease (Photo courtesy of Wikimedia Commons)

Blood Test Predicts Likelihood that Nonalcoholic Fatty Liver Disease Will Progress to Liver Cancer

A bioinformatics approach was used to transform a 133-gene panel, which could predict the likelihood of a patient with nonalcoholic fatty liver disease (NAFLD) progressing to hepatocellular carcinoma (HCC), into an easily performed four-protein blood test. Read more
23 Jun 2022 | Molecular Diagnostics

Image: Professor Colin Raston and Dr Xuan Luo with a VFD (Photo courtesy of Flinders University)

High-Tech Method for Protein Biomarker Assay Testing to Revolutionize POC Diagnosis

An accessible universal solution to offer rapid personalized mobile testing for infectious diseases – or diagnosis and delivery of targeted treatments for other diseases even in remote areas – has so far been out of reach. Read more
23 Jun 2022 | Molecular Diagnostics

Image: PictArray SARS-CoV-2 Antibody Test has received CE Mark (Photo courtesy of Pictor)

First-Ever SARS-CoV-2 Antibody Test Indicates Whether Patients Require COVID-19 Booster

The COVID-19 pandemic remains a healthcare concern as new strains of the virus have emerged. Now, a first-of-its-kind test enables personalized COVID-19 assessments by detecting if a patient has antibodies from a previous infection of SARS-CoV-2 or from vaccination alone. Read more
23 Jun 2022 | COVID-19

Image: PromarkerD blood test assesses risk of diabetic kidney disease in patients with type 2 diabetes (Photo courtesy of Proteomics)

Blood Test Detects Unique ‘Fingerprint’ of Early Onset of Diabetic Kidney Disease

Diabetic kidney disease (DKD) is a serious complication arising from diabetes which if unchecked can lead to dialysis or kidney transplant. Read more
23 Jun 2022 | Molecular Diagnostics

Image: Scientists blend AI and 3D tissue imaging to identify aggressive prostate cancer (Photo courtesy of Pexels)

AI-3D Collaboration to Provide Never-Before-Seen View and Understanding of Prostate Cancer Cells

Prostate cancer is the most common non-skin cancer in the US. Doctors will diagnose one in eight men nationally with prostate cancer, and one in 40 will die from the disease, according to the latest data. Read more
23 Jun 2022 | Pathology

Image: SARS-CoV-2 ddPCR Kit is a partition-based endpoint RT-PCR test for the qualitative detection of nucleic acids from SARS-CoV-2 (Photo courtesy of Thermo Fisher Scientific)

SARS-Cov-2 RNA Detected in FFPE Tissue by Droplet Digital PCR

SARS-CoV-2 infection can result in diverse, multiorgan pathology, the most significant being in the lungs, heart, kidney, central nervous system, liver, lymph nodes, bone marrow, vasculature, intestine, and placenta. Read more
22 Jun 2022 | COVID-19

Channels

Clinical Chem.

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Image: Simoa HD-X Analyzer was used to quantify plasma neurofilament light chain (Photo courtesy of Quanterix)

Plasma Neurofilament Light Predicts All-Cause Mortality Risk

Neurofilament light chain (NfL) is a cytoskeletal protein component exclusively expressed in neurons that is released into the extracellular fluids, including blood, during neuroaxonal damage.... Read more

Fully Automated FIT Analyzer Designed for Labs with High Fecal Testing Volumes

Colorectal Cancer (CRC) is one of the most dangerous and lethal cancers. It represents the second leading cause of cancer related death in the western world with almost two million of new cases/year and 0.... Read more

Image: The Human P-Selectin ELISA Kit – serum vimentin levels were positively correlated with P-selectin in pediatric severe sepsis (Photo courtesy of MULTI SCIENCES(LIANKE) BIOTECH, CO.,LTD).

Serum Vimentin Predicts Mortality in Pediatric Severe Sepsis

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is a leading cause of death worldwide in the pediatric population. Vascular hyperpermeability... Read more

Image: URO17 is the most sensitive and specific urine test for bladder cancer (Photo courtesy of KDx Diagnostics)

Bladder Cancer Urine Test Eliminates Invasive Cystoscopy and Unnecessary Imaging

The most common symptom of bladder cancer is hematuria, or blood in the urine, and patients with hematuria need to be subjected to invasive cystoscopic procedures even though a large majority of patients... Read more

Molecular Diagnostics

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Blood Test Can Determine Liver Disease Progression

Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide and is estimated to affect about 30% of the European population. Chronic non-alcoholic fatty liver disease... Read more

Image: The first metabolism-based multi-cancer early detection test is expected to become commercially available (Photo courtesy of Pexels)

Metabolism-Based Blood Test to Detect Multiple Cancer Types Prior to Symptoms

A pioneering metabolism-based liquid biopsy could detect any-type cancer in adults who show no symptoms or have any recent history of cancer, thereby preventing cancer mortality through early detection.... Read more

Image: New test could detect protein ‘fingerprints’ in the blood (Photo courtesy of Pexels)

Simple Blood Test for Esophageal Cancer Could Reduce Invasive Endoscopy Procedures

Barrett’s esophagus is a pre-malignant condition that occurs when the esophagus is damaged by acid reflux. Barrett’s esophagus is asymptomatic and associated with an increased risk of esophageal cancer.... Read more

Multiviral Pathogen Detection System to Revolutionize Rapid Infectious Disease Diagnosis and Tracking

An innovative molecular testing technology platform designed to rapidly and simultaneously detect and differentiate multiple pathogens with high sensitivity and specificity is poised to help revolutionize... Read more

Hematology

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Image: Peripheral blood smear from a patient with thrombotic thrombocytopenic purpura showing microangiopathic hemolytic anemia with numerous schistocytes and thrombocytopenia (Photo courtesy of Cleveland Clinic)

Cardiac Biomarkers Investigated in Acquired Refractory Thrombocytopenic Purpura Patients

Thrombotic thrombocytopenic purpura (TTP) is a rare disorder that causes blood clots (thrombi) to form in small blood vessels throughout the body. These clots can cause serious medical problems if they... Read more

Image: Bone marrow aspirate from a patient with multiple myeloma: Myeloma plasma cells with prominent anisocytosis and relatively small nuclei. Note the marginal carminophilia of cytoplasm, which is rather marked in this case (Photo courtesy of Masaryk University)

Prognostic Role for Circulating Tumor Cells Reinforced in Myeloma

Bone marrow plasma cells (BMPCs) are a marker of disease burden in monoclonal gammopathies and help discriminate among monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and... Read more

Image: XN-10 automated hematology analyzer with blood bank mode (Photo courtesy of Sysmex)

First and Only Automated Hematology Analyzer FDA-Cleared for Residual WBC Counting

Blood component quality is key in transfusion medicine and blood product manufacturing. Now, the first and only automated hematology analyzer to be FDA-cleared for residual white blood cell counting (WBC)... Read more

Donor Platelet Activation Varies by Time of Day

Platelets, are anucleate cells produced by megakaryocytes in the bone marrow that circulate in the bloodstream for about 10 days. Circulating platelets play a central role in the hemostatic response to... Read more

Immunology

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Image: Histological features of collagenous colitis (Photo courtesy of Michael Bonert, MD, FRCPC)

Lack of Autoantibodies Against Related Proteins in Collagenous Colitis

Collagenous colitis (CC) is an inflammatory disorder in the colonic mucosa that predominantly affects elderly women and causes chronic, non-bloody diarrhea with normal or close to normal endoscopic findings.... Read more

Image: The gold standard for the determination of antinuclear antibodies (ANA) is the indirect immunofluorescence test (IIFT) with human epithelial cells (HEp-2), which is known for its high sensitivity and specificity (Photo courtesy of Euroimmun)

Serological Markers of RA Determined in Patients with aβ2GPI-IgA

Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease. It is characterized by synovial inflammation that can lead to irreversible joint damage and disability when not managed.... Read more

Presepsin Proposed as 'Robust' Biomarker of Early-Onset Sepsis

Neonatal early-onset sepsis (EOS) is a severe disease, particularly in preterm infants. Timely diagnosis can be challenging owing to unspecific presentation and questionable performance of the common markers... Read more

Allogeneic Stem Cell Transplants Improve Microbiome, Immune Cells

Past studies have suggested ties between microbial diversity and favorable allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes, or transplants involving stem cells from healthy donors.... Read more

Microbiology

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Multiplex Immunoassays Enable Quantification of Malaria Antigens

The standard of care for malaria diagnosis is blood smear microscopy and antigen detection through rapid diagnostic test (RDT). Microscopy has limitations in terms of difficulty in identifying mixed infections... Read more

Image: Immunolocalization of BmR1 homologues showing immunohistochemical results from worm sections that were processed (Photo courtesy of Washington University School of Medicine)

Novel Microfilarial Antigen Diagnoses Lymphatic Filariasis Infections

Lymphatic filariasis is a neglected tropical disease caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis (LF) is a deforming and disabling disease... Read more

Image: The Weezion dx solution is designed for medical analysis hospital platforms that diagnose bacteremia (Photo courtesy of Weezion)

Diagnostic Solution Identifies Sepsis Causing Microorganisms and Predicts Antibiotic Resistance in 90 Minutes

Sepsis is a life-threatening organ dysfunction caused by the body’s toxic response to infection and can progress to septic shock, which has a mortality rate of 40%. A blood culture is the main way to check... Read more

Image: New staining method for electron microscope specimens is safe, cost-effective, and easy-to-use (Photo courtesy of Unsplash)

New Staining Method for Electron Microscope Specimens Safer and Cost-Effective

The electron microscopic staining technique for biological specimens using uranyl acetate (UA) was first reported in 1958 and has been used in electron microscopy facilities worldwide because of its simplicity... Read more

Pathology

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World's First AI-Powered Solution for Gastric Cancer Detection

Gastric cancer is a prominent malignant disease in both men and women worldwide, with over a million new cases every year and a relatively poor prognosis. Pathologists play a crucial role in the detection... Read more

Image: Histopathology of hormone receptor–positive (HR+) breast cancer (Photo courtesy of Emily S. Reisenbichler, MD)

Liquid Biopsy Identifies Breast Cancer Patients Destined to Recur

Breast cancer is the most commonly diagnosed cancer worldwide. Most breast cancers, nearly 80%, are hormone receptor–positive (HR+). Unlike other subtypes of breast cancers in which risk of recurrence... Read more

Pathology Workflow Uses AI for Analyzing Patient Samples

Rising healthcare costs, a reduction in the number of medical professionals specializing in pathology while cancer rates continue to increase inevitably drive a demand for more sophisticated and efficient... Read more

Digital Cell Morphology Platform May Replace Microscopes

With the increasing worldwide prevalence of hematological disorders and malignancies, the accuracy and timeliness of Peripheral Blood Smear (PBS) results are critically important for early diagnosis and... Read more

Technology

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Image: XT 7600 systems integrate dry chemistry (MicroSlide), wet chemistry and immunoturbidimetry with photometric detection immunoassays with enhanced chemiluminescence, and photometric measurement of sample quality indices into a single analyzer (Photo courtesy of Ortho Clinical Diagnostics)

XT MicroSlide Assays Evaluated for Performance

One of the challenges clinical laboratories face when servicing pediatric centers is adequate specimen collection from infants and children in addition to performing multiple tests on the limited sample volume.... Read more

Image: Researchers have developed a hybrid sensor that can help diagnose cancer (Photo courtesy of Pexels)

Hybrid Sensor Paves Way for Lab-on-a-Chip for Blood Testing and Cancer Detection

According to the World Health Organization, the global cancer burden was estimated at 19.3 million new cases and 10 million deaths in 2020. WHO experts believe that an estimated 30% of new cases could... Read more

Image: The integrated LIMS platform will aid more efficient lab operations with reduced errors (Photo courtesy of Holo4Labs)

LIMS Platform with Mixed Reality Tech for Hands-Free Execution of Lab Procedures

A modern laboratory information management system (LIMS) integrated with a mixed reality software solution allows laboratories to digitize their lab processes via mixed reality, freeing lab technicians... Read more

Image: World’s most advanced autonomous blood drawing device (Photo courtesy of Vitestro)

Autonomous Blood Drawing Device Combines AI, Ultrasound Imaging and Robotics

Within healthcare, the clinical laboratory is the driving force. Accuracy and timeliness of laboratory tests are critically important, as they shape approximately 70% of all medical decisions made by physicians.... Read more

BioResearch

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Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

A genomics-based blood test can predict likelihood that a baby suffering hypoxia at birth will suffer serious nervous disorders such as cerebral palsy or epilepsy at a later stage of development.... Read more

Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

Cancer researchers developed a 29 gene–based weighted prognostic score for predicting event-free survival and overall survival of patients suffering from diffuse large B-cell lymphoma (DLBCL).... Read more

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction.... Read more

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. Methods currently used to diagnose... Read more

Industry

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Quidel Partners with Global Lyme Alliance, Leads in Lyme Disease Testing

Lyme disease is a growing epidemic and more than 14% of the world’s population probably has, or has had, the tick-borne disease, as indicated by the presence of antibodies in the blood. Borrelia burgdorferi... Read more

Image: BD MAX System enables labs to fully automate and streamline their LDTs (Photo courtesy of BD)

BD and Certest Collaborate on Monkeypox Molecular Diagnostic Test

Becton, Dickinson and Company (BD Franklin Lakes, NJ, USA) and CerTest Biotec (Zaragoza, Spain) have entered into a collaboration to develop a molecular diagnostic test for the Monkeypox virus.... Read more

Image: The POC diagnostics devices and equipment market is estimated to be worth almost USD 29 billion in 2022 (Photo courtesy of Unsplash)

Global POC Diagnostics Devices and Equipment Market to Surpass USD 50 Billion in 2026

Point-of-care (POC) diagnostics devices and equipment are designed to aid physicians in performing medical diagnostic testing at or near the point of care, for immediate knowledge on diseases or conditions.... Read more

QuidelOrtho Formed by Combining Quidel and Ortho

QuidelOrtho Corporation (San Diego, CA, USA) has announced the completion of the transaction combining Quidel Corporation (San Diego, CA, USA) and Ortho Clinical Diagnostics (Raritan, NJ, USA), creating... Read more

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