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In Other News

Image: A diagram of side effects of immunotherapy (Photo courtesy of Kim Caesar).

Cytokine Levels Could Predict Immunotherapy Problems

The development of immunotherapy, which mobilizes the body's own immune system to destroy cancer cells, is one of the greatest advances in cancer treatment, but immunotherapy can cause harm to healthy tissue in some patients. Read more
13 Nov 2018 | Immunology
Image: The Bio-Plex Pro Human Inflammation Assays enable the detection and quantification of 37 key biomarkers of inflammation in a single assay (Photo courtesy of Bio-Rad Laboratories).

Biomarkers May Predict Zika-Related Birth Defects

To date, approximately 800,000 cases of suspected and confirmed autochthonous Zika virus (ZIKV) infections have been reported in the Americas. Read more
13 Nov 2018 | Immunology
Image: The automated blood culture system, the Bactec 9240 (Photo courtesy of Becton, Dickinson and Company).

Positive Blood Cultures Obtained Two Hours after Chills

Chills are feelings of coldness accompanied by shivering and they may arise with or without fever. The shaking chills are sometimes referred to as rigors. Read more
13 Nov 2018 | Microbiology
Image: The ID Core XT blood group genotyping kit (Photo courtesy of Progenika Biopharma).

Blood Compatibility Assay Approved by FDA

Blood can be grouped based on the antigens on the surfaces of red blood cells, and the presence or absence of blood group antigens other than the ABO blood group antigens can be important in matching blood for transfusions. Read more
12 Nov 2018 | Hematology
Image: A photomicrograph of heart cells (Photo courtesy of Cedars-Sinai Medical Center).

Blood Test Identifies Heart Failure with Preserved Ejection Fraction

A test based on a protein biomarker found in the blood is the basis of a scoring system that distinguishes patients with clinical heart failure with preserved ejection fraction (HFpEF) from healthy individuals and patients with risk factors but no heart failure. Read more
12 Nov 2018 | Molecular Diagnostics
Image: Four vials of human cerebral spinal fluid of normal appearance, collected via lumbar puncture (Photo courtesy of Wikimedia Commons).

Spinal Fluid Fingerprint Distinguishes Brain Infections from Diseases

Cytokine profiling has been shown to distinguish patients with infections of the brain from other diseases and may become a valuable diagnostic tool, particularly in infants and young children. Read more
12 Nov 2018 | Molecular Diagnostics
Image: The Loopamp Malaria Pan Detection Kit is a qualitative test for detection of Malaria Pan species (Plasmodium ovale, P. vivax, P. malariae and P. falciparum) in human blood samples (Photo courtesy of Human Diagnostics Worldwide).

Combined DNA Technologies Analyzed for Malaria Diagnosis

Malaria is one of the most important parasitic infectious diseases for which almost half of the world’s population is at risk. Read more
08 Nov 2018 | Microbiology
Image: The Human610-Quad BeadChip Kit uses the Infinium HD Super Assay and is compatible with the iScan, HiScan, and Bead Array Reader systems (Photo courtesy of Illumina).

Warfarin Bleeding Risk SNPs Identified in African Americans

Major Warfarin-related bleeding occurs more frequently in African Americans than in other populations. Read more
08 Nov 2018 | Molecular Diagnostics
Image: The Allplex Respiratory panel assays for the detection and identification of 26 pathogens using One-step real-time RT-PCR (Photo courtesy of Seegene).

Respiratory Panel Evaluated for Acute Respiratory Tract Infections

Upper respiratory tract infections (URTI) are illnesses caused by an acute infection that involves the upper respiratory tract including the nose, sinuses, pharynx or larynx. Read more
07 Nov 2018 | Microbiology
Image: The Pathfinder fully automated cell reader-analyzer system allows for optimized multimodal scanning, cell detection and analysis (Photo courtesy of IMSTAR).

Generic Test Developed for Early Detection of Cancer

Cancer is one of the leading causes of death worldwide. Early detection of cancer significantly raises the chances for an effective treatment. Read more
07 Nov 2018 | Pathology
Image: Next-generation Influenza A & B 2 and Strep 2 molecular assays for point-of-care cleared by FDA for use on the Abbott ID Now platform (Photo courtesy of Abbott Diagnostics).

Molecular Influenza and Streptococcus Tests Get FDA Clearance

Each year, a combination of influenza A and B virus strains circulate within the USA. The burden of influenza in the USA is currently estimated to be 9 to 36 million cases per year. Read more
07 Nov 2018 | Microbiology

Channels

Clinical Chemistry

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Novel POC Troponin Assay Rules Out Acute MI
Chronic Inflammation Linked to Risk for Alzheimer's Disease
Noninvasive Blood Glucose Test Evaluated for Accuracy
Image: The Cobas 6000 analyzer series for clinical chemistry and immunochemistry assays (Photo courtesy of Roche Diagnostics).

Plasma Lactate Measurement Used to Test Variability

Clinical laboratories are required to adhere to manufacturers’ recommended sample handling instructions as part of their compliance with accreditation certification. However, manufacturer's recommendations... Read more

Molecular Diagnostics

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Fatal Prostate Cancer Differentiated from Manageable Cancer
CD MicroRNA Marks Subtypes with Differing Outcomes
Novel Technology Enables Detection of Early-Stage Cancer
Image: Researchers have developed the first diagnostic platform that can simultaneously screen for all known human pathogenic bacteria, as well as markers for virulence and antibiotic resistance (Photo courtesy of Columbia University).

Ultrasensitive Screening Platform Detects Pathogenic Bacteria

A diagnostic platform has been developed that significantly increases the sensitivity of high-throughput sequencing for detection and characterization of bacteria, virulence determinants, and antimicrobial... Read more

Hematology

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Myeloproliferative Neoplasms Fall into Genetic Subgroups
Prognostic Value of Blood Cell Counts Investigated
Multiple Myeloma Subtypes Linked to Patient Ancestry
Image: The HiSeq 2500 System is a powerful high-throughput sequencing system (Photo courtesy of Illumina).

Functional Genomic Landscape of AML Analyzed

Acute myeloid leukemia is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.... Read more

Immunology

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Link Between Gut Flora and MS Discovered
Biomarkers Correlated with Idiopathic Inflammatory Myopathy
Tumor Markers Associated with H. Pylori Infection
Image: Immunohistochemistry staining of Helicobacter pylori on Formalin-Fixed Paraffin-Embedded (FFPE) Infected Stomach Tissue (Photo courtesy of Bio SB).

Stomach Cancer Bacterium Increases Colorectal Cancer Risk

A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans. An association of the bacteria Helicobacter pylori, the primary... Read more

Microbiology

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Detection Method for Soil-Transmitted Helminth Eggs Optimized
Multidrug-Resistant TB Outbreak Undetected by Standard Tests
New Techniques Can Detect Lyme Disease Earlier
Image: The T-SPOT.TB test is a unique, single-visit blood test for tuberculosis (TB) screening, also known as an interferon gamma release assay (IGRA) (Photo courtesy of Oxford Immunotec).

LTB Infection Estimated with Interferon-γ Release Assay

Latent tuberculosis (LTB), also called latent tuberculosis infection (LTBI) is when a person is infected with Mycobacterium tuberculosis, but do not have active tuberculosis. Active tuberculosis can be... Read more

Pathology

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Resistance of Tumor Cells to Cancer Drugs Detected
Dormant Disseminated Tumor Cells Stratified in Breast Cancer Patients
High-Risk HPV Evaluated for Invasive Cervical Cancer
Image: The QX200 Droplet Digital PCR System provides absolute quantification of target DNA or RNA molecules (Photo courtesy of Bio-Rad Laboratories).

HPV DNA Test Monitors Remission in Oral Cancer

A blood-based method has been developed to test patients with human papillomavirus-associated oral cancers for signs of remission or recurrence. This approach would potentially allow doctors to more accurately... Read more

Lab Tech.

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Low-Cost Diagnostic Developed Using Nanostructures
Residual Tissue Repositories Suitable for MS-Based Proteomics
Magnetic Nanoparticle Tool Developed to Detect MicroRNA
Image: The Cap‐Score detects and analyzes localization patterns using fluorescent microscopy to distinguish fertile from infertile sperm cells (Photo courtesy of Androvia LifeSciences).

New Test Measures Men's Fertility

Male fertility is a serious and growing concern globally. Yet, the field of andrology faces critical gaps in diagnostic technologies and knowledge, affecting scientific advancement as well as clinical... Read more

Industry News

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Increasing Conditions and Diseases Drive Global POC Hematology Diagnostics Marke...
Western Blotting Processors Market to Reach USD 329 Million by 2028
Global IVD Market to Reach USD 77 Billion by 2023
Image: The global hemostasis/coagulation analyzers market is expected to grow to USD 9.55 billion by 2026, driven mainly by the growing incidence of blood disorders (Photo courtesy of Analyticon Biotechnologies.

Global Hemostasis/Coagulation Analyzers Market to Reach USD 9.5 Billion by 2026

The global hemostasis/coagulation analyzers market was valued at USD 3.65 billion in 2017 and is expected to grow at a CAGR of 9.9% over the period 2018 to 2026 to reach USD 9.55 billion by 2026, driven... Read more

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