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Image: The test monitors blood levels of DNA fragments released by dying tumor cells (Photo courtesy of 123RF)

Gene-Based Blood Test Accurately Predicts Tumor Recurrence of Advanced Skin Cancer

Melanoma, an aggressive form of skin cancer, becomes extremely difficult to treat once it spreads to other parts of the body. Read more
16 Apr 2025 | Molecular Diagnostics
Image: A group of proteins involved in cell signaling can be used as a blood biomarker for patients with diffuse cutaneous systemic sclerosis (Photo courtesy of Shutterstock)

Blood Test Could Identify Patients at Risk for Severe Scleroderma

Systemic sclerosis, also known as scleroderma, causes the hardening of the skin and connective tissues. Read more
16 Apr 2025 | Molecular Diagnostics
Image: The UG 100 sequencing platform features unique single base flow chemistry for speed, efficiency, and accuracy (Photo courtesy of Ultima Genomics)

New Error-Corrected Method to Help Detect Cancer from Blood Samples Alone

"Liquid biopsy" technology, which relies on blood tests for early cancer detection and monitoring cancer burden in patients, has the potential to transform cancer care. Read more
16 Apr 2025 | Pathology
Image: The purple lung cancer cells in this image all have a specific genetic mutation (Photo courtesy of National Cancer Institute, National Institutes of Health)

"Metal Detector" Algorithm Hunts Down Vulnerable Tumors

Scientists have developed an algorithm capable of functioning as a "metal detector" to identify vulnerable tumors, marking a significant advancement in personalized cancer treatment. Read more
15 Apr 2025 | Pathology
Image: The test can find tRNA fragments unique to Parkinson’s disease before patients even have symptoms (Photo courtesy of Shutterstock)

Rapid Blood Test Identifies Pre-Symptomatic Patients with Parkinson’s Disease

Currently, no reliable blood test exists for diagnosing Parkinson’s disease. Instead, physicians rely on observing a patient's movements, but this qualitative method has an error rate of 20%-25% and can only be used after the disease has advanced and significant symptoms are present. Read more
15 Apr 2025 | Molecular Diagnostics
Image: The study demonstrated that electric-field molecular fingerprinting can probe cancer (Photo courtesy of ACS Central Science, 2025, 10.1021/acscentsci.4c02164)

New Method Uses Pulsed Infrared Light to Find Cancer's 'Fingerprints' In Blood Plasma

Cancer diagnoses have traditionally relied on invasive or time-consuming procedures like tissue biopsies. Read more
14 Apr 2025 | Clinical Chem.
Image: Multiplexed IF glycan imaging enables identification and quantification of cellular glycan signatures (Photo courtesy of Science Advances, DOI: 10.1126/sciadv.adt0029)

Novel Technique Uses ‘Sugar’ Signatures to Identify and Classify Pancreatic Cancer Cell Subtypes

Pancreatic cancer is often asymptomatic in its early stages, making it difficult to detect until it has progressed. Read more
14 Apr 2025 | Pathology
Image: The study validated the Lumipulse p-tau21 automated and scalable blood test system (Photo courtesy of Fujirebio)

Blood Test for Early Alzheimer's Detection Achieves Over 90% Accuracy

Alzheimer's disease (AD) is a debilitating condition and a leading cause of disability and death worldwide. Read more
14 Apr 2025 | Molecular Diagnostics
Image: The lab-in-tube assay could improve TB diagnoses in rural or resource-limited areas (Photo courtesy of Kenny Lass/Tulane University)

Handheld Device Delivers Low-Cost TB Results in Less Than One Hour

Tuberculosis (TB) remains the deadliest infectious disease globally, affecting an estimated 10 million people annually. Read more
11 Apr 2025 | Microbiology
Image: The Mirvie RNA platform predicts pregnancy complications months before they occur using a simple blood test (Photo courtesy of Mirvie)

RNA-Based Blood Test Detects Preeclampsia Risk Months Before Symptoms

Preeclampsia remains a major cause of maternal morbidity and mortality, as well as preterm births. Despite current guidelines that aim to identify pregnant women at increased risk of preeclampsia using general maternal characteristics, the incidence of the disease has nearly doubled over the last decade, now affecting 1 in 12 pregnancies. Read more
11 Apr 2025 | Molecular Diagnostics
Image: Research has revealed how pathogenic antibodies from six different patients bind to the AChR to cause myasthenia gravis (Photo courtesy of Huanhuan Li/Hibbs Lab, UC San Diego)

Advanced Imaging Reveals Mechanisms Causing Autoimmune Disease

Myasthenia gravis, an autoimmune disease, leads to muscle weakness that can affect a range of muscles, including those needed for basic actions like blinking, smiling, or moving. Read more
11 Apr 2025 | Pathology
Image: The test is the first of its kind to use microRNAs to predict toxicity from cancer therapy (Photo courtesy of 123RF)

First Of Its Kind Test Uses microRNAs to Predict Toxicity from Cancer Therapy

Many men with early-stage prostate cancer receive stereotactic body radiotherapy (SBRT), a highly precise form of radiation treatment that is completed in just five sessions. Read more
11 Apr 2025 | Molecular Diagnostics
Image: Schematic illustration of the chip (Photo courtesy of Biosensors and Bioelectronics, DOI: https://doi.org/10.1016/j.bios.2025.117401)

Pain-On-A-Chip Microfluidic Device Determines Types of Chronic Pain from Blood Samples

Chronic pain is a widespread condition that remains difficult to manage, and existing clinical methods for its treatment rely largely on self-reporting, which can be subjective and especially problematic for patients who cannot communicate verbally. Read more
10 Apr 2025 | Technology
Image: The anti-MAG CBA expands EUROIMMUN’s portfolio of assays for detection of neural autoantibodies (Photo courtesy of Frontiers in Neurology)

Novel Cell-Based Assay Provides Sensitive and Specific Autoantibody Detection in Demyelination

Anti-myelin-associated glycoprotein (MAG) antibodies serve as markers for an autoimmune demyelinating disorder that affects the peripheral nervous system, leading to sensory impairment. Read more
10 Apr 2025 | Molecular Diagnostics

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Clinical Chemistry

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Paper-Based Device Boosts HIV Test Accuracy from Dried Blood Samples
AI-Powered Raman Spectroscopy Method Enables Rapid Drug Detection in Blood
Novel LC-MS/MS Assay Detects Low Creatinine in Sweat and Saliva
Image: Carbon nanotubes with different chirality or “twist” have different optical properties (Photo courtesy of Mikael Nyberg/University of Turku)

Carbon Nanotubes Help Build Highly Accurate Sensors for Continuous Health Monitoring

Current sensors can measure various health indicators, such as blood glucose levels, in the body. However, there is a need to develop more accurate and sensitive sensor materials that can detect lower... Read more

Molecular Diagnostics

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Blood Test Rules Out Future Dementia Risk
D-Dimer Testing Can Identify Patients at Higher Risk of Pulmonary Embolism
New Biomarkers to Improve Early Detection and Monitoring of Kidney Injury
Image: The low-cost test builds on existing platform that assesses COVID-19 and water quality (Photo courtesy of 123RF)

Novel Point-of-Care Technology Delivers Accurate HIV Results in Minutes

HIV diagnostic methods have traditionally relied on detecting HIV-specific antibodies, which typically appear weeks after infection. This delayed detection has hindered early diagnosis, complicating patient... Read more

Hematology

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Non-Invasive Prenatal Test for Fetal RhD Status Demonstrates 100% Accuracy
WBC Count Could Predict Severity of COVID-19 Symptoms
New Platelet Counting Technology to Help Labs Prevent Diagnosis Errors
Image: The 3-parameter CCRS model was devised specifically for patients diagnosed with clonal cytopenia (Photo courtesy of 123RF)

New Scoring System Predicts Risk of Developing Cancer from Common Blood Disorder

Clonal cytopenia of undetermined significance (CCUS) is a blood disorder commonly found in older adults, characterized by mutations in blood cells and a low blood count, but without any obvious cause or... Read more

Immunology

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Machine Learning-Enabled Blood Test Predicts Immunotherapy Response in Lymphoma ...
Post-Treatment Blood Test Could Inform Future Cancer Therapy Decisions
Cerebrospinal Fluid Test Predicts Dangerous Side Effect of Cancer Treatment
Image: The cancer stem cell test can accurately choose more effective treatments (Photo courtesy of University of Cincinnati)

Stem Cell Test Predicts Treatment Outcome for Patients with Platinum-Resistant Ovarian Cancer

Epithelial ovarian cancer frequently responds to chemotherapy initially, but eventually, the tumor develops resistance to the therapy, leading to regrowth. This resistance is partially due to the activation... Read more

Microbiology

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Breakthrough Diagnostic Technology Identifies Bacterial Infections with Almost 100%...
Innovative ID/AST System to Help Diagnose Infectious Diseases and Combat AMR
Gastrointestinal Panel Delivers Rapid Detection of Five Common Bacterial Pathogens...
Image: The AI-based method can more accurately detect antibiotic resistance in deadly bacteria such as tuberculosis and staph (Photo courtesy of Adobe Stock)

New AI-Based Method Improves Diagnosis of Drug-Resistant Infections

Drug-resistant infections, particularly those caused by deadly bacteria like tuberculosis and staphylococcus, are rapidly emerging as a global health emergency. These infections are more difficult to treat,... Read more

Pathology

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AI Model Predicts Patient Response to Bladder Cancer Treatment
New Laser-Based Method to Accelerate Cancer Diagnosis
New AI Model Predicts Gene Variants’ Effects on Specific Diseases
Image: The AI-based model can help pathologists grade certain lung cancer tumors and predict patients’ outcomes (Photo courtesy of Anne Weston, Francis Crick Institute)

AI Model Effectively Predicts Patient Outcomes in Common Lung Cancer Type

Lung adenocarcinoma, the most common form of non-small cell lung cancer (NSCLC), typically adopts one of six distinct growth patterns, often combining multiple patterns within a single tumor.... Read more

Technology

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Smartphones Could Diagnose Diseases Using Infrared Scans
Novel Sensor Technology to Enable Early Diagnoses of Metabolic and Cardiovascular...
3D Printing Breakthrough Enables Large Scale Development of Tiny Microfluidic De...
Image: Pictorial representation of the working principle of a functionalized Carbon Dots CDs and EB based Func sensor (Photo courtesy of Toppari/University of Jyväskylä)

Innovative, Label-Free Ratiometric Fluorosensor Enables More Sensitive Viral RNA Detection

Viruses present a major global health risk, as demonstrated by recent pandemics, making early detection and identification essential for preventing new outbreaks. While traditional detection methods are... Read more

Industry

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Leica Biosystems and Bio-Techne Expand Spatial Multiomic Collaboration
Philips and Ibex Expand Partnership to Enhance AI-Enabled Pathology Workflows
Grifols and Inpeco Partner to Deliver Transfusion Medicine ‘Lab of The Future’
Image: The Procollagen-III-peptide (PIIINP) ELISA kit (Photo courtesy of Cisbio Bioassays)

Tecan Acquires ELISA Immunoassay Assets from Revvity's Cisbio Bioassays

Tecan Group (Männedorf, Switzerland) has entered into an agreement to acquire certain assets relating to key ELISA immunoassay products from Cisbio Bioassays SAS (Codolet, France), a subsidiary of the... Read more

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