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Image: The UriBLAD gene expression test system is intended for urothelial cancer detection (Photo courtesy of Canhelp Genomics)

Non-Invasive AI-Powered Urine Test Enables Early Bladder Cancer Detection

Urothelial carcinoma, the most common type of bladder cancer, ranks among the top 10 most prevalent cancers globally, with an estimated 573,278 new cases and 212,536 deaths in 2020. Read more
26 Nov 2024 | Molecular Diagnostics
Image: Image: Eight-week-old mouse brain (Photo courtesy of Science)

New Microscopy Method Enables Detailed Whole Brain 3D RNA Analysis

Despite significant advancements in RNA analysis, linking RNA data to its spatial context, particularly in intact, detailed three-dimensional (3D) tissue volumes, has remained a challenging task. Read more
26 Nov 2024 | Pathology
Image: New study findings highlight significant advancements in development of an MCED test (Photo courtesy of Exact Sciences)

New Multi-Biomarker Class Approach Improves Cancer Detection

Cancer is expected to become the leading cause of death in the U.S. by 2030. Only about 14% of all cancers in the U. Read more
25 Nov 2024 | Molecular Diagnostics
Image: The deep learning AI model can sometimes catch signs of disease that human pathologists miss (Photo courtesy of Eric Nilsson, Skinner Laboratory, WSU)

AI Model Identifies Signs of Disease Faster and More Accurately Than Humans

Traditionally, researchers and medical professionals identify pathology, or signs of disease, by meticulously examining and annotating tissue samples under a microscope, a process that can take hours for each slide or image. Read more
25 Nov 2024 | Pathology
Image: Patho-DBiT reveals cellular level tissue architecture of an aggressive gastric lymphoma sample stored for 3 years (Photo courtesy of Yale)

New Barcode Technology to Help Diagnose Cancer More Precisely

A new pathology tool utilizing barcode technology shows promise for use in cancer diagnoses. Developed at Yale School of Medicine (New Haven, CT, USA), this tool, called Patho-DBiT (pathology-compatible deterministic barcoding in tissue), leverages DNA barcoding to map the spatial relationships between RNA and proteins, enabling a comprehensive examination of RNA, some types of which play regulatory roles in cancer. Read more
22 Nov 2024 | Pathology
Image: The Headstart test measures five biomarkers in urine (Photo courtesy of Global Access Diagnostics)

AI Urine Test Predicts COPD Flares Before Symptoms Appear

Chronic obstructive pulmonary disease (COPD) affects over 400 million people worldwide and is expected to become the third leading cause of death by 2030. Read more
22 Nov 2024 | Molecular Diagnostics
Image: The cost-effective, easy-to-use test can categorize a child’s cancer and better guide treatment (Photo courtesy of St. Jude Children’s Research Hospital)

New Liquid Biopsy Panel Targets Pediatric Cancers

Identifying mutations in a child's cancer using advanced sequencing technologies can significantly improve treatment outcomes. Read more
21 Nov 2024 | Molecular Diagnostics
Image: Patients can be divided into three groups with different disease severity based on composition of smooth muscle cells in blood vessels (Photo courtesy of Melody Chemaly)

Mapping of Atherosclerotic Plaque Cells Predicts Future Risk of Stroke or Heart Attack

Atherosclerosis is the leading cause of cardiovascular diseases like heart attacks and strokes. Over many years, atherosclerotic plaques develop from the accumulation of blood lipids such as cholesterol in the innermost layer of blood vessels. Read more
21 Nov 2024 | Pathology
Image: The study findings suggest that tumor-infiltrating lymphocytes are a robust biomarker of breast cancer (Photo courtesy of Shutterstock)

AI Analysis of Immune Cells Predicts Breast Cancer Prognosis

Tumor-infiltrating lymphocytes (TILs) are immune cells crucial in combating cancer. Their presence in a tumor indicates that the immune system is attempting to attack and eliminate cancer cells. Read more
20 Nov 2024 | Pathology
Image: A quick finger prick and few drops of blood on a card could make Alzheimer’s testing more accessible (Photo courtesy of Shutterstock)

Finger Prick Blood Test to Enable Early Alzheimer’s Detection

A new approach using a quick finger prick and a few drops of blood on a card that can be sent in regular mail could make Alzheimer’s testing much more accessible worldwide. Read more
20 Nov 2024 | Molecular Diagnostics
Image: Small molecule modulation of protein corona significantly enhances deep plasma proteome profiling (Photo courtesy of Mahmoudi Group)

Smarter Blood Tests Deliver Faster Diagnoses and Improved Outcomes

It has long been established that the earlier a disease is detected, the better the chances for a positive patient outcome. Read more
19 Nov 2024 | Molecular Diagnostics
Image: Photoacoustic images of a splayed vessel structure underlying very light and dark skin tones (Photo courtesy of asquinha, Gubbi, and Bell, doi 10.1117/1.BIOS.2.1.012502)

New Imaging Technique Reduces Skin Tone Bias in Breast Cancer Detection

Breast cancer remains a significant global health issue, and early detection is key to successful treatment. Read more
19 Nov 2024 | Pathology
Image: The AI program analyzes a microscopy image from a tumor biopsy and determines what genes are likely turned on and off in the cells it contains (Photo courtesy of Olivier Gevaert/Stanford Medicine)

AI Tool ‘Sees’ Cancer Gene Signatures in Biopsy Images

To assess the type and severity of cancer, pathologists typically examine thin slices of a tumor biopsy under a microscope. Read more
18 Nov 2024 | Pathology

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Image: The new saliva-based test for heart failure measures two biomarkers in about 15 minutes (Photo courtesy of Trey Pittman)

POC Saliva Testing Device Predicts Heart Failure in 15 Minutes

Heart failure is a serious condition where the heart muscle is unable to pump sufficient oxygen-rich blood throughout the body. It ranks as a major cause of death globally and is particularly fatal for... Read more

Molecular Diagnostics

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Cutting-Edge Diagnostic Tool Rapidly Identifies Emerging SARS-CoV-2 Variants
Novel Method Analyzes Genetic Variations in Families with High Incidence of Breast...
cfDNA Testing Reduces Pregnancy Risks
Image: The clinical laboratory workflow for mNGS (Photo courtesy of UCSF)

Single Metagenomic Next-Generation Sequencing Test Can Detect All Infectious Pathogens

Metagenomic next-generation sequencing (mNGS) is a comprehensive sequencing method that analyzes all nucleic acids (DNA and RNA) in a clinical sample at high depth, generating 10-20 million sequences per sample.... Read more

Hematology

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Next Gen CBC and Sepsis Diagnostic System Targets Faster, Earlier, Easier Results...
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Image: The smartphone technology measures blood hemoglobin levels from a digital photo of the inner eyelid (Photo courtesy of Purdue University)

First-Of-Its-Kind Smartphone Technology Noninvasively Measures Blood Hemoglobin Levels at POC

Blood hemoglobin tests are among the most frequently conducted blood tests, as hemoglobin levels can provide vital insights into various health conditions. However, traditional tests are often underutilized... Read more

Immunology

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Advanced Imaging Method Maps Immune Cell Connections to Predict Cancer Patients ...
Computational Tool Predicts Immunotherapy Outcomes for Metastatic Breast Cancer ...
Biomarker Could Predict Immunotherapy Response in Liver Cancer
Image: Under a microscope, DNA repair is visible as bright green spots (“foci”) in the blue-stained cell DNA. Orange highlights actively growing cancer cells (Photo courtesy of WEHI)

Simple Blood Test Could Detect Drug Resistance in Ovarian Cancer Patients

Every year, hundreds of thousands of women across the world are diagnosed with ovarian and breast cancer. PARP inhibitors (PARPi) therapy has been a major advancement in treating these cancers, particularly... Read more

Microbiology

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High-Accuracy Bedside Test to Diagnose Periprosthetic Joint Infection in Five Mi...
Innovative Diagnostic Approach for Bacterial Infections to Enable Faster and Eff...
Non-Invasive Stool Test to Diagnose Endometriosis and Help Reduce Disease Progre...
Image: HNL Dimer can be a novel and potentially useful clinical tool in antibiotic stewardship in sepsis (Photo courtesy of Shutterstock)

Unique Blood Biomarker Shown to Effectively Monitor Sepsis Treatment

Sepsis remains a growing problem across the world, linked to high rates of mortality and morbidity. Timely and accurate diagnosis, along with effective supportive therapy, is essential in reducing sepsis-related... Read more

Pathology

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AI Tool Identifies Novel Genetic Signatures to Personalize Cancer Therapies
AI Tool Detects Cancerous Brain Tumor During Surgery in 10 Seconds
AI-Powered Whole-Slide Image Analyzer Predicts Immunotherapy Response for Rare C...
Image: A large field-of-view, single-cell-resolution two- and three-photon microscope for deep and wide imaging (Photo courtesy of Mok, A.T., Wang, T., Zhao, S. et al.; doi.org/10.1186/s43593-024-00076-4)

New Microscope Offers Unprecedented Deep and Wide-Field Visualization of Brain Activity at Single-Cell Resolution

Conventional multiphoton microscopy, which is fundamental for deep-tissue imaging, faces significant challenges related to imaging depth and field of view, particularly in highly scattering biological... Read more

Technology

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Nanomaterial-Based Diagnostic Technology Accurately Monitors Drug Therapy in Epi...
New Noninvasive Methods Detect Lead Exposure Faster, Easier and More Accurately at...
Noninvasive Test Detects Malaria Without Blood Sample
Image: A label-free optical biosensor-based point-of-care test for the rapid detection of Monkeypox virus (Photo courtesy of Biosensors and Bioelectronics)

Optical Biosensor Rapidly Detects Monkeypox Virus at Point of Care

A new variant of human mpox has caused a mortality rate of approximately 5% among those infected in the Democratic Republic of the Congo since 2023, with many of the victims being children.... Read more

Industry

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Roche to Develop New Diagnostic Technologies for Traumatic Brain Injuries
LGC Clinical Diagnostics and AccuGenomics Collaborate on Enhancing Cancer Testing...
Beckman Coulter and SphingoTec Partner to Improve Kidney Health Assessment in Cr...
Image: CACLP 2025 will return on 21-24 March 2025 to attract professionals across the IVD industry (Photo courtesy of CACLP)

CACLP 2025 New Date and Venue Announced

The 22nd China International In Vitro Diagnostic Expo, organized by the China Association of Clinical Laboratory Practice Expo (CACLP, Shanghai, China), is set to take place from March 21 to 24, 2025,... Read more

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