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New COVID-19 Antibody Test Platform Combines Antibody Testing and Blockchain Technology

New Mount Sinai Venture to Manufacture and Distribute COVID Antibody Test Kits Globally

Antibody Detection Is Critical for COVID-19 Diagnosis

World’s First SARS-CoV-2 Serology Test Detects Neutralizing Antibodies Without Containment Facility or Specimen

DxGen Launches '2 Minutes' COVID-19 Antibody Testing System

Giemsa Stain Outperforms Urease Test for Helicobacter Pylori Diagnosis

Thermo Fisher to Distribute Chembio’s DPP COVID-19 System in US

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

06 Jun 2020 - 10 Jun 2020
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EAACI Congress 2020 – European Academy of Allergy & Clinical Immunology

06 Jun 2020 - 09 Jun 2020
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ESGH 2020 – European Human Genetics Conference

08 Jun 2020 - 11 Jun 2020
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BIO International Convention 2020

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MEDICAL FAIR ASIA 2020 Set to Take Place in Singapore from 9-11 December 2020

Yale Researchers Use Single-Cell Analysis and Machine Learning to Identify Major COVID-19 Target

Monkeys Demonstrate Immunity Against Novel Coronavirus in New Study

Biogen and Vir Biotechnology Partner to Manufacture SARS-CoV-2 Antibodies for Potential COVID-19 Treatment

Study Finds Immunity to Coronavirus May Last Only Six Months with Reinfection Possible

Need for Rapid Containment Measures to Drive Growth of Global COVID-19 Detection Kits Market

New One-Minute COVID-19 Test Detects Antibodies from Single Drop of Blood

Air Science’s Purair BIO Biological Safety Cabinet Provides Safe Laboratory Workspace

NIH Launches Global COVID-19 Digital Pathology Repository

Supply Chain Issues Continue to Impact Labs Providing SARS-CoV-2 Testing, Finds AMP Survey

HEMCO Corporation’s MicroFlow I Ductless Workstation Ensures Safety Comes First

Swift Biosciences Launches Normalase Amplicon Panel (SNAP) SARS-CoV-2 Kit

Bio-Rad Collaborates with Biodesix to Launch Blood-Based Immunoassay-Based Test to Detect Coronavirus Antibodies

More COVID-19 News

Global Spread of the Multi-Resistant Pathogen Stenotrophomonas Maltophilia Revealed

Image: Stenotrophomonas maltophilia colonies on sheep blood agar. Cultivation 48 hours in an aerobic atmosphere, 37 °C (Photo courtesy of microbiologyinpictures).

Stenotrophomonas maltophilia strains occur in several natural and human associated ecosystems. The bacterium was long regarded as relatively unproblematic, but is now considered to be one of the most feared hospital pathogens, as it frequently causes infections and is resistant to a number of antibiotics. Read more
28 May 2020

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LINEAR CHEMICALS, S.L.

Cytokine Signatures of Tertian Malaria Infection Profiled During Pregnancy

27 May 2020

Silver Nanocubes Make Point-of-Care Diagnostics Easier to Read

27 May 2020

Elevated Metal Ion Level Detects Defective Hip Arthroplasty Implants

26 May 2020

MicroRNA Biomarker Panel Identifies Patients at Risk for Pancreatic Cancer Metastasis to the Lymph Nodes

26 May 2020

Representative Tumor Sampling Method Lessens Molecular Analyses Bias

25 May 2020

Industry Spotlight

Nova Biomedical Adds PT/INR Test to Allegro Analyzer for POC Testing

Nova Biomedical (Waltham, MA, USA) has added PT/INR testing for its Allegro capillary blood analyzer for point-of-care (POC) testing in primary care settings. Read more
08 Apr 2020

Global Blood Glucose Monitoring Devices Market to Reach USD 13 Billion by 2023

The global blood glucose monitoring devices (BGMDs) market was valued at nearly USD 8 billion in 2018 and is projected to grow at a fast-paced CAGR of approximately 11% to reach USD 13 billion by 2023, driven by the phenomenal sales growth of new revolutionary continuous glucose monitoring systems (CGMs). Read more
16 Mar 2020

Global ELISA Kits Market to Surpass USD 418.5 Billion by 2025

The global ELISA (Enzyme-Linked Immunosorbent Assay) Kits market is projected to grow at a CAGR of 3. Read more
09 Mar 2020

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In Other News

Image: 3d Illustration of Glucose Molecule (Photo courtesy of Shutterstock)

Need for Rapid Containment Measures to Drive Growth of Global COVID-19 Detection Kits Market

The growth of the global COVID-19 detection kits market will be driven by the responsiveness of countries to contain the spread of the coronavirus and advancements in healthcare facilities. Read more
30 May 2020 | COVID-19

Supply Chain Issues Continue to Impact Labs Providing SARS-CoV-2 Testing, Finds AMP Survey

Preliminary results of a SARS-CoV-2 testing survey for clinical laboratories have revealed that more than 70% have experienced supply chain interruptions that have resulted in significant delays. Read more
30 May 2020 | COVID-19

Image: An INSTI test for SARS-CoV-2 (Photo courtesy of bioLytical Laboratories Inc.)

New One-Minute COVID-19 Test Detects Antibodies from Single Drop of Blood

A one-minute test for antibodies to SARS-CoV-2 is currently being developed based on an innovative testing technology that detects antibodies within one minute from a single drop of blood. Read more
30 May 2020 | COVID-19

Image: MicroFlow I Ductless Workstation (Photo courtesy of HEMCO Corporation)

HEMCO Corporation’s MicroFlow I Ductless Workstation Ensures Safety Comes First

Amidst the current pandemic, laboratory biosafety related to the coronavirus has assumed significant importance for laboratories and stakeholders involved in COVID-19 laboratory work. Read more
29 May 2020 | COVID-19

Image: The Purair® BIO biological safety cabinet (Photo courtesy of Air Science)

Air Science’s Purair BIO Biological Safety Cabinet Provides Safe Laboratory Workspace

Biosafety in the laboratory is critical when work involves infectious diseases and toxins, as well as in cell and tissue culturing, where product contamination must be avoided, particularly amidst the current COVID-19 pandemic. Read more
29 May 2020 | COVID-19

Image: Swift Normalase Amplicon Panel (SNAP) SARS-CoV-2 kit (Photo courtesy of Swift Biosciences, Inc.)

Swift Biosciences Launches Normalase Amplicon Panel (SNAP) SARS-CoV-2 Kit

Swift Biosciences, Inc. (Ann Arbor, MI, USA), which focuses on commercialization of DNA and RNA library preparation kits for Next-Generation Sequencing (NGS), has released its Swift Normalase Amplicon Panel (SNAP) SARS-CoV-2 kit. Read more
29 May 2020 | COVID-19

NIH Launches Global COVID-19 Digital Pathology Repository

The National Institutes of Health {(NIH) Bethesda, MD, USA} has launched the online COVID Digital Pathology Repository (COVID-DPR), a virtual collection of high resolution microscopic COVID-related human tissue images. Read more
28 May 2020 | COVID-19

Image: BioRad QX200 Digital Droplet PCR System (Photo courtesy of Bio-Rad Laboratories, Inc.)

Bio-Rad Collaborates with Biodesix to Launch Blood-Based Immunoassay-Based Test to Detect Coronavirus Antibodies

Bio-Rad Laboratories, Inc. (Hercules, CA, USA) has entered into a collaboration with Biodesix, Inc. (Boulder, CO, USA) to launch a blood-based immunoassay-based test that identifies antibodies to SARS-CoV-2. Read more
28 May 2020 | COVID-19

Roche Elecsys Anti-SARS-CoV-2 Antibody Test Goes Live at More than 20 Initial Lab Sites in US

Roche’s (Basel, Switzerland) Elecsys Anti-SARS-CoV-2 antibody test is currently live at more than 20 commercial and hospital lab sites throughout the US, with plans in the next several weeks to increase to more than 200 commercial and hospital lab sites with the ability to perform millions of tests per week. Read more
28 May 2020 | COVID-19

Image: COVID-19 Total Antibody Test and Molecular Test Kit (Photo courtesy of Siemens Healthineers)

Siemens Begins Shipping COVID-19 Total Antibody Test and Molecular Test Kit Globally

Siemens Healthineers (Erlangen, Germany) has begun worldwide shipping of its laboratory-based total antibody test to detect the presence of SARS-CoV-2 IgM and IgG antibodies in blood. Read more
27 May 2020 | COVID-19

Aalto Bio Launches New Recombinant Eukaryotic SARS-CoV-2, S1-S2 Spike Proteins for COVID-19 Testing

Aalto Bio Reagents Ltd. (Dublin, Ireland) has launched its new range of recombinant SARS-CoV-2 spike (S) proteins for diagnostic test manufacturers, vaccine developers and researchers globally. Read more
26 May 2020 | COVID-19

Image: Fulgent`s Specimen Collection Kit (Photo courtesy of Fulgent Genetics, Inc.)

Fulgent Receives FDA Emergency Use Authorization for SARS-CoV-2 RT-PCR Test

Fulgent Genetics, Inc. (Temple City, CA, USA) has received Emergency Use Authorization (EUA) from the US Food and Drug Administration (FDA) for its RT-PCR test for the detection of SARS-CoV-2 using upper respiratory specimens (nasal, nasopharyngeal, and oropharyngeal swabs). Read more
26 May 2020 | COVID-19

Channels

Clinical Chemistry

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Image: The Vertex 70 Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectrophotometer (Photo courtesy of the University of Guelph).

Salivary Molecular Spectroscopy Used to Monitor Diabetes

Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia which results from insufficient secretion and/or reduced insulin action in peripheral tissues. Frequent monitoring of diabetes... Read more

Image: Histology of multinucleated giant cells engulfing calcium oxalate crystals from a patient with type 1 primary hyperoxaluria (Photo courtesy of Jonathan E. Zuckerman, MD, PhD).

Biomarker Panel Evaluated for Primary Hyperoxaluria Patients

Primary hyperoxaluria (PH) is a group of autosomal recessive disorders characterized by recurrent urinary stones and nephrocalcinosis. Roughly half of PH patients present with advanced chronic kidney disease... Read more

Image: The Vanquish Flex Ultra High Performance Liquid Chromatography (UHPLC) Systems (Photo courtesy of Thermo Fisher Scientific).

HPLC Method Developed for Vitamin B6 Quantitation

Symptoms of vitamin B6 deficiency can include dermatitis, glossitis, depression, confusion, convulsions, and anemia. Inborn errors affecting vitamin B6 metabolism have been associated with vitamin B6-dependent... Read more

Elevated Vitamin-B12 Level Lowers Risk of Parkinson’s Disease Dementia

Previous studies found that, among people with Parkinson’s, those with cognitive impairment, such as dementia, had significantly lower levels of vitamin B12 in their blood. This suggests the possibility... Read more

Molecular Diagnostics

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Image: A multisegment injection-non-aqueous-capillary electrophoresis–mass spectrometer (MSI-NACE-MS) (Photo courtesy of McMaster University)

An Analytical Method to Monitor Dietary Fat Intake

An advanced analytical technique was used to determine unequivocally the composition of fats in the diets of pregnant women and female patients suspected of being deficient in certain dietary fats.... Read more

Image: Germline Risk Variants Found in Prostate Cancer Patients Using the Heredity Testing Kit (Photo courtesy of Invitae).

Germline Risk Variants Found in Prostate Cancer Patients

Studies done over the past five years or so have unearthed pathogenic germline variants in some 12% to 17% of men with prostate cancer, and such alterations can impact everything from the treatment options... Read more

Non-Invasive Blood Assay Can Detect Early Colorectal Cancer

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). In general, colon cancer begins... Read more

New Blood Test Can Determine When an Individual Was Exposed to a Pathogenic Microorganism

An international research team has developed a diagnostic blood test – initially for the recurring form of vivax malaria – that can determine when an individual was exposed to a pathogenic microorganism,... Read more

Hematology

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Image: The UniCel DxI 800 Access Immunoassay System (Photo courtesy of Beckman Coulter).

Soluble Transferrin Receptor Investigated in Iron Deficiency Anemia

Anemia is a global public health problem and approximately 30% of the world's population suffered from anemia, with children and pregnant women being the most affected. Microcytic hypochromic anemia is... Read more

Image: A blood smear from a patient with microcytosis which may predict underlying cancer even in the presence of normal hemoglobin. Microcytic red blood cells measure 6 μm or less in diameter. The mean corpuscular volume is generally less than 80 fL (Photo courtesy of Sara Beth Fazio, MD).

Microcytosis Is a Risk Marker of Cancer in Primary Care

Microcytosis is a term used to describe red blood cells that are smaller than normal. Anemia is when there are low numbers of properly functioning red blood cells in the body. In microcytic anemia, the... Read more

Image: The CS-2400 is a high performance coagulation station that allows laboratories to perform routine and specialized testing including platelet function tests (Photo courtesy of Sysmex).

Lupus Anticoagulant Prolongs Activated Partial-Thromboplastin Time in COVID-19

Patients with coronavirus disease 2019 (COVID-19) have a profound hypercoagulable state, and complicating venous thrombotic events are common. Abnormalities in coagulation screening measures, including... Read more

Image: The ACL Top 550 hemostasis analyzer (Photo courtesy of Werfen).

Blood Clotting Causes Significant Mortality in COVID-19 Patients

Although the underlying pulmonary pathophysiology remains incompletely understood, severe COVID-19 infection is associated with a marked alveolar inflammatory cell infiltrate, together with a systemic... Read more

Immunology

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Image: CTL- Immunospot Analyzers come in a wide range of models, each of which is designed to make assay analysis faster, easier, and more accurate than ever before (Photo courtesy of Cellular Technology Limited).

Initial Immune Response After Dengue Virus Infection Identified

Dengue virus (DENV) is a member of the clinically-relevant Flavivirus genus together with Zika virus, yellow fever virus and others. With four distinct serotypes, DENV is thought to infect between 280... Read more

Immune Microenvironment Changes Contribute to Early-Stage Multiple Myeloma

Multiple myeloma is a cancer that forms in a type of white blood cell called a plasma cell. Plasma cells help you fight infections by making antibodies that recognize and attack germs. Multiple myeloma... Read more

Image: The Simultest IMK-Lymphocyte is a two-color direct immunoﬂuorescence reagent kit for enumerating percentages of the following mature human leucocyte subsets in erythrocyte-lysed whole blood (Photo courtesy of BDBiosciences).

Immune Responses Evaluated for Tick-Borne Encephalitis

Tick-borne encephalitis (TBE) is an important vector-borne infection of the central nervous system (CNS). The majority of all reported cases of TBE occur in adults. However, TBE should also be included... Read more

Image: Linking peptide specificities with T cell transcriptomes (Photo courtesy of University of California, Santa Cruz).

High-Throughput T Cell Profiling Technique Developed

T cells recognize foreign or aberrant antigens presented by major histocompatibility complex (MHC-I) expressing cells through the T cell receptor (TCR) and is the first critical step towards establishment... Read more

Microbiology

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Different Methods Compared for Species Identification of Enterococcus

Biochemical test‐based methodologies are still used in some laboratories for the identification of bacterial isolates, mainly because of the need for the performance of drug susceptibility tests.... Read more

Image: Salmonella are gram-negative, rod-shaped, facultative anaerobic bacteria. Newly developed sensitive and specific assays are able to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens (Photo courtesy of Public Health Image Library, [U.S.] Centers for Disease Control and Prevention)

A Series of Sensitive and Specific DNA-Based Assays Detects and Differentiates Salmonella Serotypes

A team of Australian researchers developed a series of sensitive and specific assays to detect and identify different serotypes (serovars) of Salmonella, a common cause of bacterial foodborne disease worldwide.... Read more

Giemsa Stain Outperforms Urease Test for Helicobacter Pylori Diagnosis

More than 50% of the worldwide population is infected by Helicobacter pylori which is harbored in their upper gastrointestinal tract. Despite having chronic gastritis, most people infected by H.... Read more

Image: The Oxford Nanopore MinION device (Photo courtesy of Oxford Nanopore Technologies).

Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples

Posterior oropharyngeal saliva samples are a non-invasive specimen more acceptable to patients and health-care workers. Unlike severe acute respiratory syndrome, patients with COVID-19 had the highest... Read more

Pathology

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$Image: Schematic diagram of circulating tumor DNA (ctDNA) which is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized. Once ctDNA is isolated, it can be sequenced for mutational analysis (Photo courtesy of Rachel June Wong).$

Blood Test Shows Promise for Predicting Cancer

Early detection of most cancers is an elusive and daunting task; nevertheless, it has remained a top priority for the cancer research community. Detecting cancer early has manifold advantages: it can increase... Read more

Bacterial Blood Infections Tied to Heightened Colon Cancer Risk

Colorectal cancer occurs in the colon or the rectum and it is the third most common type of cancer in the USA. Around 90% of cases occur in people aged 50 years or older. As well as age, risk factors include... Read more

Image: Multicancer Blood Test Aids Screen for Cancer Guide Intervention (Photo courtesy of fotoquique/Depositphotos).

Multicancer Blood Test Aids Screen for Cancer Guide Intervention

As minimally invasive screening tests, liquid biopsies could help reduce cancer-specific morbidity and mortality through earlier detection. However, there is debate on how to effectively screen large populations... Read more

Image: Histopathological micrograph of pancreatic adenocarcinoma arising in the pancreas head region (Photo courtesy of KGH).

Biomarker Data Improves Risk Prediction for Pancreatic Cancer

Pancreatic cancer risk prediction models based on clinical factors may be refined and improved by bringing in other types of data, including germline genetic risk variant and blood-based biomarker data.... Read more

Lab Tech.

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Image: Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging (Photo courtesy of Massachusetts General Hospital Research Institute).

Ultra-Fast Cycling for Multiplexed Cellular Fluorescence Imaging

In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. Until now, analyses of these dynamic changes with... Read more

Image: Electronic Nose Device Can Detect Esophageal Cancer Precursor (Photo courtesy of Radboud University Medical Center).

Esophageal Cancer Precursor Detected by Electronic Nose Device

Barrett's esophagus is a condition in which the lining of the esophagus changes, becoming more like the lining of the small intestine rather than the esophagus. This occurs in the area where the esophagus... Read more

Image: the Vivalytic multiplex PCR platform (Photo courtesy of Randox Laboratories)

Analyzer Platform for Simultaneous Detection of Multiple Sexually Transmitted Infections Is Now CE-marked

The British health diagnostic company Randox Laboratories (Crumlin, United Kingdom) announced receipt of CE-marking for its Biochip-based assay, which tests for 10 sexually transmitted infections (STIs)... Read more

Image: The VITROS XT 3400 Chemistry System (Photo courtesy of Ortho Clinical Diagnostics)

New Chemistry Analyzer Completes Ortho Clinical Diagnostics’ Catalogue of VITROS XT Solutions

Ortho Clinical Diagnostics (Raritan, NJ, USA) has announced the launch and availability of the VITROS XT 3400 Chemistry System, which completes the company’s catalogue of VITROS XT Solutions.... Read more

BioResearch

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Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

Cancer researchers developed a 29 gene–based weighted prognostic score for predicting event-free survival and overall survival of patients suffering from diffuse large B-cell lymphoma (DLBCL).... Read more

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction.... Read more

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. Methods currently used to diagnose... Read more

Image: Spiked rods of monosodium urate crystals photographed under polarized light from a synovial fluid sample. Formation of monosodium urate crystals in the joints is associated with gout (Photo courtesy of Wikimedia Commons).

Panel of Genetic Loci Accurately Predicts Risk of Developing Gout

A large GWAS (genome-wide association study) highlighted genetic loci associated with the metabolic regulation of serum levels of uric acid (urate) and identified a panel of 183 loci linked to the risk... Read more

Industry News

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Thermo Fisher Scientific to Acquire QIAGEN N.V.

Thermo Fisher Scientific Inc. (Waltham, MA, USA) has announced that it plans to acquire QIAGEN N.V. (Venlo, Netherlands), a provider of molecular diagnostics and sample preparation technologies.... Read more

New AI System Performs as Well as Expert Pathologists in Identifying Prostate Cancer

Researchers at the Karolinska Institutet (Stockholm, Sweden) and Tampere University (Tampere, Finland) have developed a method based on artificial intelligence (AI) for histopathological diagnosis and... Read more

Quest Diagnostics Acquires Blueprint Genetics

Quest Diagnostics (Secaucus, NJ, USA), a provider of diagnostic information services, has acquired Blueprint Genetics (Helsinki, Finland), a specialty genetic testing company with expertise in gene variant... Read more

Nova Biomedical Launches New BioProfile FLEX2 On-Line Autosampler

Nova Biomedical (Waltham, MA, USA) has launched the BioProfile FLEX2 On-Line Autosampler (OLS), a modular system that connects as many as 10 bioreactors to one FLEX2 analyzer for up to three weeks of walkaway,... Read more

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