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Certest Offers Real-Time PCR Assays for Fast Detection of MDR Bacterial Infections

Bioperfectus Demonstrates Nucleic Acid Extraction Solutions at AACC 2021

Thermo Fisher Launches World’s First Fully Integrated Digital PCR (dPCR) System

Global Digital Polymerase Chain Reaction (dPCR) Market Projected to Reach Close to USD 1.15 Billion by 2028

Machine Learning Tools for COVID-19 Patient Screening Discussed at AACC 2021

Meridian Launches New Air-Dryable qPCR Mix Enabling Direct Detection of RNA from Whole Blood Samples

Siemens Wireless, Handheld Patient-Side Immunoassay Analyzer Enables Industry First Fingerstick High-Sensitivity hs-cTnI Testing at POC

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

20 Oct 2021 - 22 Oct 2021

MEDLAB Asia Pacific 2021

21 Oct 2021 - 24 Oct 2021
Virtual Venue

SIOP 2021 – Annual Congress of the International Society of Paediatric Oncology (SIOP).

21 Oct 2021 - 24 Oct 2021
Virtual Venue

EndoBridge 2021

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Vascular Closure System Permits Same-Day Discharge

Portable Extracorporeal System Preserves Organs for Transplantation

Assessing Stiffness of Arteries Could Help Identify Patients Most at Risk of Dying From COVID-19

Newly Identified Highly Potent Monoclonal Antibody Against SARS-CoV-2 Neutralizes All COVID-19 Variants of Concern

Microneedle Array Patch Pierces Bacterial Biofilms

Newly-Launched Portable Molecular Diagnostic Platform Detects COVID-19 at Point-of-Care within 30 Minutes

Lateral Flow Tests for COVID-19 More Accurate than Previously Reported, Cannot Be Compared to PCR Tests

New Nanomechanical Technique for Fast, One-Step, Immune-Affinity Tests Rapidly Quantifies Transmissibility of COVID-19 Variants

Pooled Saliva Testing for COVID-19 Can Be Cheaper and as Accurate as Individual Nasopharyngeal Diagnostic Tests

Next Generation SARS-CoV-2 Test Measures Response to COVID-19 Vaccine and Neutralizing Antibody Levels in 10 Minutes

Study Examines Proteins in Saliva to Predict COVID-19 Severity Risk in Children with Help of AI Model

CT Values Should Not Be Used to Assess Performance of SARS-CoV-2 PCR Tests or Triage COVID-19 Patients, Finds Study

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Fecal Immunochemical Tubes Sourced to Analyze Gut Microbiome for CRC

Image: The QuikRead go iFOBT is an immunochemical fecal immunochemical test for detection and quantification of human hemoglobin in feces in case of suspected bleeding from the lower gastrointestinal tract (Photo courtesy of Aidian)

Colorectal cancer (CRC) is a challenging public health problem which successful treatment depends on the stage at diagnosis. Recently, CRC-specific microbiome signatures have been proposed as a marker for CRC detection. Read more
14 Oct 2021

Plasma Amyloid-β 42/40 Assays Compared in Alzheimer Disease

14 Oct 2021

First-of-Its-Kind Testing Device Allows For Rapid Detection of Bacteria That Identify Risk for Preterm Birth

14 Oct 2021

Mutation Analysis Links Angioimmunoblastic T-Cell Lymphoma to Clonal Hematopoiesis

13 Oct 2021

Unique Gene Detects Mycobacterium Tuberculosis in Clinical Sputum

13 Oct 2021

Folate, Vitamin B12 Tied to GDM Risk in Early Pregnancy

12 Oct 2021

Industry Spotlight

Biohit’s Innovative GastroPanel Quick Test Receives CE Mark

Biohit Healthcare’s (Helsinki, Finland) GastroPanel Quick Test, the latest innovation in its unique GastroPanel product family, is now CE marked. Read more
15 Oct 2021

Global Point-of-Care (POC) Testing Market to Reach Nearly USD 80 Billion by 2028 due to Increasing Dominance of Infectious Diseases

The global Point-Of-Care (POC) testing market is projected to grow at a CAGR of 12.3% from USD 31.17 billion in 2020 to USD 78. Read more
15 Oct 2021

Thermo Fisher Launches World’s First Fully Integrated Digital PCR (dPCR) System

Thermo Fisher Scientific Inc. (Waltham, MA, USA) has launched the world’s first fully integrated digital PCR (dPCR) system designed to provide highly accurate and consistent results within 90 minutes. Read more
22 Sep 2021

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Image: The PEBBLE qcLAMP Platform (Photo courtesy of BIOPIX-T)

Newly-Launched Portable Molecular Diagnostic Platform Detects COVID-19 at Point-of-Care within 30 Minutes

A new portable molecular diagnostic platform and its compatible diagnostic test for the detection of SARS-CoV-2 delivers results within 30 minutes at the Point-of-Care (POC). Read more
15 Oct 2021 | COVID-19

Image: Lateral Flow Tests for COVID-19 More Accurate than Previously Reported, Cannot Be Compared to PCR Tests (Photo courtesy of Bastion Riccardi (CC 2.0))

Lateral Flow Tests for COVID-19 More Accurate than Previously Reported, Cannot Be Compared to PCR Tests

Lateral flow tests (LFTs) for COVID-19 are more accurate than previously reported and cannot be compared directly to how polymerase chain reaction (PCR) tests work, according to new research. Read more
15 Oct 2021 | COVID-19

Image: New Nanomechanical Technique for Fast, One-Step, Immune-Affinity Tests Rapidly Quantifies Transmissibility of COVID-19 Variants (Photo courtesy of Trinity College Dublin)

New Nanomechanical Technique for Fast, One-Step, Immune-Affinity Tests Rapidly Quantifies Transmissibility of COVID-19 Variants

A team of researchers has developed a new nanomechanical technique for fast, one-step, immune-affinity tests, which can quantify the immune response induced by different COVID-19 variants in serum. Read more
14 Oct 2021 | COVID-19

Pooled Saliva Testing for COVID-19 Can Be Cheaper and as Accurate as Individual Nasopharyngeal Diagnostic Tests

Testing pooled saliva samples twice weekly for SARS-CoV-2 on a residential college campus yielded a greater than 95% agreement with the gold standard for accuracy—nasopharyngeal diagnostic samples tested singly. Read more
14 Oct 2021 | COVID-19

Next Generation SARS-CoV-2 Test Measures Response to COVID-19 Vaccine and Neutralizing Antibody Levels in 10 Minutes

The second generation version of a rapid neutralizing antibody test for COVID-19 will not only show if the users have responded to their COVID-19 vaccine but also perform a semi-quantitative analysis of their neutralizing antibody levels in a single test. Read more
13 Oct 2021 | COVID-19

Study Examines Proteins in Saliva to Predict COVID-19 Severity Risk in Children with Help of AI Model

A team of researchers is conducting a study to look at the relationship between proteins called cytokines in saliva and COVID-19 infection to help predict the severity of infection with the help of an artificial intelligence (AI) model. Read more
13 Oct 2021 | COVID-19

CT Values Should Not Be Used to Assess Performance of SARS-CoV-2 PCR Tests or Triage COVID-19 Patients, Finds Study

A novel study has shown that coronavirus test cycle threshold (Ct) values should not be used to assess the performance of coronavirus tests or to triage COVID-19 patients. Read more
13 Oct 2021 | COVID-19

Image: Effect of whole-genome sequencing on the clinical management of acutely ill infants with suspected genetic disease investigated (Photo courtesy of Illumina)

Whole-Genome Sequencing Applied to Acutely Ill Infants

Critically ill infants admitted to an intensive care unit are at risk for high levels of morbidity and mortality. Read more
12 Oct 2021 | Molecular Diagnostics

Image: Micrograph showing a lymph node invaded by ductal breast carcinoma, with an extension of the tumor beyond the lymph node (Photo courtesy of Wikimedia Commons)

High Cell-Free DNA Integrity Is a Biomarker for Poor Breast Cancer Survival

A team of Finnish researchers has refined a liquid biopsy analysis technique to act as a more specific biomarker in order to more accurately predict poor prognosis for patients with aggressive breast cancer. Read more
12 Oct 2021 | Molecular Diagnostics

Image: KANEKA RT-PCR Kit SARS-CoV-2 (Photo courtesy of Kaneka Corporation)

New SARS-CoV-2 Kit Simultaneously Detects Four COVID-19 Variants with Single RT PCR Test

A new real-time PCR test kit is capable of simultaneously detecting four variants of COVID-19. Kaneka Corporation (Tokyo, Japan) has launched its new KANEKA RT-PCR Kit SARS-CoV-2 (L452R/E484Q/E484K/N501Y), a real-time PCR test kit that is capable of simultaneously detecting four variants of COVID-19. Read more
12 Oct 2021 | COVID-19

Image: Characteristic bronchoalveolar lavage findings of diffuse alveolar hemorrhage (Photo courtesy of Peter C. Bauer, MD)

Bronchoalveolar Lavage Cell Pattern Determined for Diffuse Alveolar Hemorrhage

Diffuse alveolar hemorrhage (DAH) is a clinicopathological syndrome that describes the accumulation of intra-alveolar red blood cells originating from the alveolar capillaries. Read more
11 Oct 2021 | Pathology

Image: Pictured is a cross section of a peripheral artery from the leg of a patient with chronic limb-threatening ischemia (CLTI), a condition in which heavy plaque formation causes a severe narrowing of the arteries (Photo courtesy of Zayed Research Laboratory, Washington University School of Medicine)

Elevated Circulating Fatty Acid Synthase Is a Diagnostic Biomarker for Peripheral Artery Disease

Elevated levels of a soluble form of the enzyme fatty acid synthase (sFSA) in the blood have been linked to development of the severe vascular disorder peripheral artery disease (PAD). Read more
11 Oct 2021 | Molecular Diagnostics

Meridian Launches New Air-Dryable qPCR Mix Enabling Direct Detection of RNA from Whole Blood Samples

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has launched its new Air-Dryable Direct RNA/DNA qPCR Blood Mix, an innovative master mix designed to develop room-temperature stable molecular diagnostic assays that directly amplify RNA from crude whole blood, serum, or plasma. Read more
08 Oct 2021 | Hematology

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Clinical Chem.

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Carolina Liquid Chemistries Corp. Introduces Line of Water Systems for Clinical Chemistry Analyzers

Carolina Liquid Chemistries, Corp. (CLC, Greensboro, NC, USA) has introduced a new line of laboratory water systems to the US market. The water system is offered in two models for compatibility with a... Read more

Image: DxU Iris Workcell Urinalysis Solution (Photo courtesy of Beckman Coulter, Inc.)

Beckman Coulter New Urinalysis Solution Improves Laboratory Workflow by Reducing Manual Reviews and Sample Processing Time

Beckman Coulter, Inc. (Brea, CA, USA) has launched the DxU Iris Workcell, its new fully automated system that streamlines urinalysis workflow and reduces manual reviews to 4%. A routine urinalysis is... Read more

Image: Higher blood high density lipoprotein and apolipoprotein A1 levels are associated with reduced risk of developing amyotrophic lateral sclerosis (Photo courtesy of Forth)

Blood Lipid Biomarkers Associated with Lower Risk of ALS

Amyotrophic lateral sclerosis (ALS) ALS belongs to a wider group of disorders known as motor neuron diseases, which are caused by gradual deterioration (degeneration) and death of motor neurons.... Read more

Image: The Ketonix Breath Ketone Analyzer may be considered as a non-invasive screening tool to rule out ketosis in adults with type 1 diabetes (Photo courtesy of Ketonix)

Breath Ketone Analyzer Accurately Detects Ketosis in Type 1 Diabetes

The presence of high levels of ketones in the bloodstream is a common complication of diabetes, which if left untreated can lead to ketoacidosis. Ketones build up when there is insufficient insulin to... Read more

Molecular Diagnostics

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ALPK3 Truncating Variants Cause Autosomal Dominant Hypertrophic Cardiomyopathy

In hypertrophic cardiomyopathy, heart muscles are thicker, which can make it harder for the heart to receive and pump blood. While in most cases the condition will not affect daily life, it can cause heart... Read more

Next-Generation Multiomics Blood-Based Test for Pancreatic Cancer Could Become Powerful Tool for Early Diagnosis and Treatment

Freenome Holdings, Inc. (South San Francisco, CA, USA) has demonstrated the potential of extending its multiomics approach into other cancers, such as pancreatic cancer, with biomarkers already embedded... Read more

New State-of-the-Art, Ultrasensitive Blood Test to Transform Detection of Brain Damage and Poor Prognosis After Head Injury

A new study has used a state-of-the-art blood test to track damage to the brain in people who have sustained traumatic brain injury (TBI). The study by researchers from the UK DRI Care Research and Technology... Read more

Image: Blood smear from a P. falciparum culture. Several red blood cells have ring stages inside them. Close to the center is a schizont and on the left a trophozoite (Photo courtesy of Wikimedia Commons)

WHO Warning: Rapid Tests Misdiagnose Many Cases of P. falciparum Malaria in Africa

A pair of mutations, which result in deletion of the Plasmodium falciparum histidine-rich protein 2 (HRP2), render the malaria parasite invisible to the most commonly used rapid diagnostic tests.... Read more

Hematology

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Image: QScout RLD (Photo courtesy of Advanced Animal Diagnostics)

Rapid Hematology Analyzer for Early Detection of Severe Infection to Deliver Laboratory Grade Results in Two Minutes

An innovative, easy-to-use system for the earlier detection of severe infection, including sepsis, is being designed for use at point of care in urgent care clinics, doctors' offices and other pre-hospital... Read more

IFN-γ Signature Distinguishes Pediatric Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS

Hemophagocytic lymphohistiocytosis (HLH), severe sepsis, and persistent systemic inflammatory response syndrome are all conditions defined by excessive immune activation that may progress rapidly and are... Read more

Image: The Navios EX flow cytometer offers a solution for advanced cytometry applications with workflows for high throughput laboratories (Photo courtesy of Beckman Coulter)

Artificial Intelligence Helps Diagnose Leukemia

Multi-parameter flow cytometry (MFC) is a cornerstone in clinical decision making for leukemia and lymphoma. MFC data analysis requires manual gating of cell populations, which is time-consuming, subjective,... Read more

Mindray Launches New MC-80 Automated Digital Cell Morphology Analyzer

Mindray (Shenzhen, China), a leading global medical solutions provider, has launched the new MC-80 Automated Digital Cell Morphology Analyzer, a revolutionary cell morphology system that provides more... Read more

Immunology

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Image: The BD LSRFortessa X-20 Cell Analyzer can be configured with up to five lasers to detect up to 20 parameters simultaneously to support ever increasing demands in multicolor flow cytometry (Photo courtesy of BD Biosciences)

Highly Multiplexed Cell Surface Protein Analyzed Via Flow Cytometry

Modern immunologic studies increasingly requires high-dimensional analyses to understand the complex milieu of cell types that comprise the tissue microenvironments of disease. One of the cornerstones... Read more

Image: The Pylon 3D Fully Automated Immunoassay System (Photo courtesy of ET Healthcare)

Novel Assay Measures Interleukin-6 in Whole Blood Samples

Interleukin 6 (IL-6) is a pleiotropic cytokine produced by various stromal cells and immune system cells, involved in inflammation and infection responses, regeneration process, metabolism regulation,... Read more

Image: Siemens Healthineers’ new Atellica VTLi patient-side immunoassay analyzer (Photo courtesy of Siemens Healthineers)

Siemens Wireless, Handheld Patient-Side Immunoassay Analyzer Enables Industry First Fingerstick High-Sensitivity hs-cTnI Testing at POC

Siemens Healthineers’ (Erlangen, Germany) new Atellica VTLi patient-side immunoassay analyzer marks a vital leap forward in cardiac testing by offering clinicians the first high-sensitivity troponin I... Read more

Image: BD LSRFortessa is a high-end cell analyzer. It is equipped with four lasers allowing for up to 16 colors (18 parameters) analysis (Photo courtesy of ETH Zurich)

Environmental Allergens Trigger Type 2 Inflammation Through Ripoptosome Activation

Environmental allergens, including fungi, insects and mites, trigger type 2 immunity; however, the innate sensing mechanisms and initial signaling events remain unclear. The allergens trigger activity... Read more

Microbiology

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Image: The QIAcube is an automated system which can extract DNA or RNA from up to 12 samples simultaneously (Photo courtesy of Qiagen)

PCR Assay Detects and Differentiates Coccidioides Species

Coccidioidomycosis (Valley Fever) is a pulmonary and systemic fungal disease with increasing incidence and expanding endemic areas. The differentiation of etiologic agents Coccidioides immitis and C.... Read more

Image: Next Generation Phenotyping Platform from Selux (Photo courtesy of Selux Diagnostics, Inc.)

Next Generation Rapid Antibiotic Susceptibility Testing (AST) Platform Granted FDA Breakthrough Device Designation

Selux Diagnostics, Inc.’s (Boston, MA, USA) Next Generation Phenotyping (NGP) platform has received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA) for positive blood culture... Read more

Image: Graphic representation of genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer (Photo courtesy of University of Washington School of Medicine)

Gut Bacteria Are Possible Indicators of Colon Cancer Risk

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum. Signs and symptoms may include blood in the stool, a change in... Read more

Image: The Invitrogen Qubit 4 Fluorometer is designed to accurately measure DNA, RNA, and protein quantity (Photo courtesy of Thermo Fisher Scientific)

Blood Testing Distinguishes Benign Tumors from Precancerous Condition

The leading cause of mortality for patients with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the development of malignant peripheral nerve sheath tumor (MPNST), an aggressive soft... Read more

Pathology

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Image: Circulating tumor DNA (ctDNA) is found in the bloodstream and refers to DNA that comes from cancerous cells and tumors. The LiquidHALLMARK assay, a liquid biopsy test, tracks treatment-based ctDNA changes (Photo courtesy of Jonathan Bailey, National Human Genome Research Institute)

Liquid Biopsy Test Tracks Treatment-Based ctDNA Changes

Metastatic or unresectable disease is identified in approximately 20% of patients presenting with invasive urothelial cancer. In addition, up to 50% of patients will develop metastases following radical... Read more

Image: Histopathology photomicrograph of lymphocytic esophagitis: Esophageal mucosa showing peripapillary intraepithelial lymphocytosis with basal zone hyperplasia and intercellular edema. No significant population of eosinophils or neutrophils is identified (Photo courtesy of Yusuf Kasirye, MD, et al)

CD8 T-Cell–Predominant Lymphocytic Esophagitis Associated with GERD

In patients with reflux esophagitis (RE), increased lymphocytes are often part of a mixed inflammatory infiltrate that also includes eosinophils and/or neutrophils. Less frequently, lymphocytes are the... Read more

Certest Offers Real-Time PCR Assays for Fast Detection of MDR Bacterial Infections

CerTest Biotec (Zaragoza, Spain) has joined the fight against multidrug resistant strains (MDR) bacterial infections by developing real-time PCR assays for the fast detection of genes or punctual mutations that confer resistance to antibiotics from both Gram-positive and Gram-negative pathogens. Resistance to antibiotics... Read more

PD-L1 Expression in Circulating Tumor Cells Investigated for NSCLC

In non-small cell lung cancer (NSCLC), analysis of programmed cell death ligand 1 (PD-L1) expression in circulating tumor cells (CTCs) is a potential alternative to overcome the problems linked to the... Read more

Technology

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Manual Aspiration by Monovette Reduces Hemolytic Sampling

Hemolytic blood samples are the number one cause for specimen rejection at emergency departments (ED). Triggered by unsuitable blood sampling material or incorrect handling and a related strong vacuum... Read more

Image: Nanoanalysis of plasma volatile organic compounds used novel DNA-decorated carbon nanotube vapor sensors to noninvasively distinguish ovarian and pancreatic cancer from benign and control samples (Photo courtesy of the University of Pennsylvania)

Electronic Nose Sensor Accurately Detects Ovarian, Pancreatic Cancers

Ovarian cancer is a cancer that forms in or on an ovary. It results in abnormal cells that have the ability to invade or spread to other parts of the body. When this process begins, there may be no or... Read more

Image: (c) Illustration of workflow for human buccal swab sample testing on the toroidal PCR. Total turnaround time is under one hour. (d) Genotyping 15 SNP loci from buccal swab samples from a family trio (Photo courtesy of Rice University)

Portable, PCR-Based Assay Developed for Rapid, Multiplexed DNA Detection

The detection of specific DNA sequences is central to precision medicine, from pathogen identification to the risk assessment of human genetic diseases to disease prognosis. While technologies exist for... Read more

New Technology Can Diagnose Infections in Minutes

The detection and identification of bacteria currently rely on enrichment steps such as bacterial culture and nucleic acid amplification to increase the concentration of target analytes.... Read more

BioResearch

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Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

A genomics-based blood test can predict likelihood that a baby suffering hypoxia at birth will suffer serious nervous disorders such as cerebral palsy or epilepsy at a later stage of development.... Read more

Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

Cancer researchers developed a 29 gene–based weighted prognostic score for predicting event-free survival and overall survival of patients suffering from diffuse large B-cell lymphoma (DLBCL).... Read more

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction.... Read more

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. Methods currently used to diagnose... Read more

Industry

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Global Digital Polymerase Chain Reaction (dPCR) Market Projected to Reach Close to USD 1.15 Billion by 2028

The global digital polymerase chain reaction (dPCR) market is projected to grow at a CAGR of more than 9% from over USD 0.50 billion in 2020 to nearly USD 1.15 billion by 2028, driven primarily by rising... Read more

Mesa Laboratories to Acquire Molecular Diagnostics Tools Company Agena Bioscience

Mesa Laboratories, Inc. (Lakewood, CO, USA) has entered into a definitive agreement to acquire Agena Bioscience, Inc. (San Diego, CA, USA). Mesa is a global leader in the design and manufacturing of... Read more

Global Blood, Gas and Electrolyte Analyzers Market Projected to Reach Nearly USD 3.5 Billion by 2023

The global blood, gas and electrolyte analyzers market is projected to grow at a CAGR of 8.6% from more than USD 2.1 billion in 2016 to nearly USD 3.5 billion by the end of 2023, driven by rapid developments... Read more

Global In Vitro Diagnostics (IVD) Quality Control Market Projected to Reach USD 1.4 Billion by 2026

The global in vitro diagnostics (IVD) quality control market is projected to grow at a CAGR of 5.3% from USD 1.1 billion in 2021 to USD 1.4 billion by 2026, thanks to the significant role played by IVD... Read more

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