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Trending Articles

Rhinomed Announces European Launch of Revolutionary New Swab for Testing Children for Respiratory Diseases

Immune Reaction to Gut Bacterium May Trigger Rheumatoid Arthritis

Artificial Intelligence Methods Could Replace Histochemical Staining

Advanced Mass Spectrometry Could Provide Microscopic Clues to Beating Deadly Brain Tumors

Independent Subtype of Idiopathic Multicentric Castleman Disease Defined

AI-Based Staining Technique as Accurate as Traditional Histopathology in Assessing Breast Cancer Biomarker

Leica Biosystems Acquires Cell IDx, Expanding Offerings in Multiplexed Tissue Profiling

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Rhinomed Announces European Launch of Revolutionary New Swab for Testing Children for Respiratory Diseases

Fecal Immunochemical Test a Less Expensive Alternative for Colorectal Cancer Screening

Portable, Sample to Answer PCR Device Delivers Accurate Results in 30 Minutes at Point of Need

Bosch Demonstrates Vivalytic All-In-One PCR Analyzer at MEDICA 2022

Biovendor Group Presents CLIA Solution for Complex Diagnostics at MEDICA 2022

Diatron Exhibits Advanced Hematology and Clinical Chemistry Analyzers at MEDICA 2022

Immundiagnostik AG Presents New PCR Test MutaPLEX RespiraScreen4_Diff_seqc at MEDICA 2022

Eurotrol Presents the Future of Blood Gas Controls at MEDICA 2022

Owen Mumford Presents Cutting-Edge Capillary Blood Sampling Devices for POC Testing

Gut Microbiome Dysbiosis Linked to COVID-19

Novel SARS CoV-2 Rapid Antigen Test Validated for Diagnostic Accuracy

New COVID + Flu + R.S.V. Test to Help Prepare for `Tripledemic`

AI Takes Guesswork Out Of Lateral Flow Testing

Fastest Ever SARS-CoV-2 Antigen Test Designed for Non-Invasive COVID-19 Testing in Any Setting

Rapid Antigen Tests Detect Omicron, Delta SARS-CoV-2 Variants

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

29 Nov 2022 - 02 Dec 2022

ASI 2022 – 50th Annual Scientific Meeting of the Australian and New Zealand Society for Immunology

01 Dec 2022 - 02 Dec 2022

JIB 2022 - Journees de l`Innovation en Biologie

05 Dec 2022 - 08 Dec 2022

BSI Congress 2022 – British Society for Immunology

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Wearable Neurostimulation Solution Could Stem Excessive Blood Loss in the OR

Benchtop Immunoanalyzer Delivers Lab Quality Results for Cardiology, Intensive Care and Emergency Wards at POC

Global Visualization Instruments for MIS Market Driven by Increasing Demand for Endoscopy Procedures

Miniaturized Biosensors Open New Possibilities for Minimally Invasive Implants

Warmer Brain-Irrigation Fluid Can Halve Number of Repeat Operations for Subdural Hemorrhage

First-Ever Blood Test Could Detect Deadly Heart Inflammation Within Hours

Image: A cheap blood test could improve diagnosis of myocarditis (Photo courtesy of Queen Mary University of London)

Myocarditis, or inflammation of the heart muscle, is a difficult condition to diagnose. Now, the discovery of a molecular signal in the blood could pave the way for the first blood test to be used for diagnosing myocarditis within as little as a year. Read more
25 Nov 2022

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Urine-Based, Non-Invasive Molecular Test Accurately Detects Bladder Cancer

25 Nov 2022

Altered Ratios of p53 Isoforms Predict Response of Breast Tumors to Chemotherapy

24 Nov 2022

Revolutionary, Non-Invasive Technique Measures Glucose Levels Without Drawing Blood

24 Nov 2022

Interleukins and Vitamin D Evaluated in Women With Graves' Disease

23 Nov 2022

Blood Test Could Screen for Changes in Proteins Prior to Breast Cancer Diagnosis

23 Nov 2022

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Industry Spotlight

Leica Biosystems Acquires Cell IDx, Expanding Offerings in Multiplexed Tissue Profiling

Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging (Nussloch, Germany), has acquired Cell IDx, Inc. Read more
09 Nov 2022

Roche Introduces Digital Health Solutions Under Navify Brand

Roche (Basel, Switzerland) has announced that its digital health portfolio will now be available under the navify brand. Read more
08 Nov 2022

Werfen to Acquire Transfusion and Transplant Diagnostics Innovator for Around USD 2 Billion

Werfen (Barcelona, Spain) has agreed to acquire Immucor, Inc. (Norcross, GA, USA), a privately held corporation with a global presence in transfusion and transplant in vitro diagnostics, at a purchase price of approximately USD 2 billion. Read more
08 Nov 2022

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In Other News

Image: TruSight Lymphoma 40 uses expert-defined content and proven next-generation sequencing (NGS) technology to identify somatic variants associated with lymphomas (Photo courtesy of Illumina)

Tumor Biopsies Analysis Performed on Newly-diagnosed B-cell Neoplasms

Comprehensive genomic analyses of tumor biopsies from patients with newly-diagnosed germinal center B cell (GCB) diffuse large B cell/high grade B cell lymphoma (DLBCL/HGBL) have identified molecular subtypes predictive of inferior survival, which are characterized by somatic mutations that can be detected through clinical laboratory mutation analysis (CLMA). Read more
22 Nov 2022 | Molecular Diagnostics

Image: Equivalence of Genetically Elevated LDL and Lipoprotein(a) on Myocardial Infarction (Photo courtesy of Viborg Regional Hospital)

Familial Hypercholesterolemia Patients With ACD Have Elevated Lipoprotein(a)

Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein (LDL cholesterol), in the blood and early cardiovascular disease. Read more
22 Nov 2022 | Clinical Chem.

Image: Mild versus severe immune response during COVID-19 infection (Photo courtesy of Wikimedia Commons)

Acute COVID-19 Infections Are Characterized by Elevated Blood Levels of IL-26

The most severe form of COVID-19 infection is characterized by elevated levels of the cytokine interleukin-26 (IL-26) in the blood. Read more
22 Nov 2022 | Molecular Diagnostics

Image: The developed micro-costing framework. cfDNA, cell-free DNA; ctDNA, circulating tumor DNA (Photo courtesy of the Amsterdam University Medical Centers)

New Tool Assesses Cost of ctDNA Testing

Circulating tumor DNA (ctDNA) is a promising new biomarker with multiple potential applications in cancer care. Read more
22 Nov 2022 | Molecular Diagnostics

Image: The Xpert Xpress MVP PCR test aids in faster identification of three distinct conditions within an hour (Photo courtesy of Cepheid)

Multiplex Vaginal Panel Identifies Three Distinct Conditions in One Hour

Each year, about 10 million healthcare visits by women in the U.S. are related to vaginitis symptoms. Read more
22 Nov 2022 | Molecular Diagnostics

Image: EONIS SCID-SMA kit is the first U.S. FDA authorized assay for SMA screening in newborns (Photo courtesy of PerkinElmer)

Novel Assay Enables Simultaneous Detection of SMA and SCID in Newborns

Spinal muscular atrophy (SMA) is a leading genetic cause of infant death and is characterized by muscle weakness and atrophy resulting from progressive degeneration and loss of the lower motor neurons in the spinal cord and the brain stem nuclei. Read more
22 Nov 2022 | Molecular Diagnostics

Image: Liver cancer is the third-leading cause of cancer-related deaths worldwide (Photo courtesy of Delfi Diagnostics)

Simple Blood Test Could More Than Double Liver Cancer Detection Rate in High-Risk Population

The ravages of liver cancer are underappreciated in terms of their public health impact. The mortality rate from the disease has risen steadily over decades, making it the sixth leading cancer killer in the United States and the third-leading cause of cancer-related deaths worldwide. Read more
22 Nov 2022 | Molecular Diagnostics

Image: The compact xMAP INTELLIFLEX system is a flow-based, multiplex platform that simplifies the workflow by combining the established performance of xMAP technology (Photo courtesy of Thermo Fisher Scientific)

Assay Developed to Measure Anti-Factor VIII Antibodies

Hemophilia is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. Read more
21 Nov 2022 | Hematology

Image: The Clarifi mTBI saliva test collection device (Photo courtesy of Quadrant Biosciences)

First-Ever Saliva-Based Concussion Test to Be Available in 2023

According to the (CDC), 1.6 to 3.8 million athletes will experience a sports-related mild traumatic brain injury (mTBI) or concussion each year. Read more
21 Nov 2022 | Molecular Diagnostics

Image: Liver cancer is the third leading cause of cancer deaths worldwide (Photo courtesy of Pexels)

AI Blood Test Detects Liver Cancer

More than 800,000 people are diagnosed with liver cancer worldwide each year, and it is a leading cause of cancer deaths worldwide, according to the American Cancer Society. Read more
21 Nov 2022 | Molecular Diagnostics

Image: genoSCORE-LAB is a genetic test for risk assessment in Alzheimer`s disease (Photo courtesy of Cytox)

Non-Invasive Saliva Test Predicts Future Risk for Alzheimer's

The risk of developing Alzheimer’s disease has several components; depending on an individual’s genes, he or she may have been born with a higher or lower risk of developing the disease. Read more
21 Nov 2022 | Molecular Diagnostics

Image: The CFTR protein is a channel protein that controls the flow of H2O and Cl- ions into and out of cells inside the lungs. When the CFTR protein is working correctly, as shown in Panel 1, ions freely flow in and out of the cells. However, when the CFTR protein is malfunctioning as in Panel 2, these ions cannot flow out of the cell due to a blocked channel. This causes cystic fibrosis, characterized by the buildup of thick mucus in the lungs (Photo courtesy of Wikimedia Commons)

A Urine Test for Detection and Management of Cystic Fibrosis

A simple urine test was developed that both identifies individuals with cystic fibrosis and determines the effectiveness of the drug treatment being used to control the disease. Read more
16 Nov 2022 | Molecular Diagnostics

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Clinical Chem.

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Image: Thermo Scientific BRAHMS KRYPTOR Compact Plus Automated Immune Analyzer (Photo courtesy of machinio)

Circulating Angiogenic Factor Levels Predict Hypertensive Disorders of Pregnancy

Preeclampsia is the most common hypertensive disorder associated with pregnancy. The severe form of the disease can lead to dangerously high blood pressure, organ failure, vision loss or even stroke.... Read more

Image: A Human Lipocalin-2/ neutrophil gelatinase-associated lipocalin (NGAL) sandwich ELISA kit (Photo courtesy of Epitope Diagnostics Inc.)

Urine Neutrophil Gelatinase-Associated Lipocalin Predicts Acute Kidney Injury

Despite the increasing heterogeneity of etiology, making a definitive and timely diagnosis of acute kidney injury (AKI) remains challenging. Currently, the diagnosis of AKI is still based on elevated serum... Read more

New Blood Cholesterol Testing System Is Cheaper, More Efficient, and Faster

Total cholesterol contained in the body within normal limits is an important substance, without which the proper functioning of the body is impossible. Elevated blood cholesterol is a symptom of a number... Read more

New Analyzer Monitors Blood Ammonium Levels at POC to Facilitate Quick Medical Decisions

Ammonium is a biomarker used to diagnose a series of rare hereditary metabolic disorders, such as the primary disorders of the urea cycle and different organic acidemias, as well as other metabolic and... Read more

Molecular Diagnostics

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Image: Dark field photomicrograph (magnified 400X) showing the spirochetes, or corkscrew-shaped bacteria, known as Borrelia burgdorferi, which is the pathogen responsible for causing Lyme disease (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)

Gene Signature Identifies Patients with Long-term Lyme Disease

A transcriptomics approach was used to establish a 35-gene signature that could be used to identify individuals with long-term Lyme disease and distinguish them from those with the acute form of Lyme disease... Read more

Image: The Applied Biosystems Quant Studio 6 Pro Real-Time PCR System adds innovative smart features to the real-time PCR (qPCR) workflow, all in a compact footprint (Photo courtesy of Thermo Fisher Scientific)

Direct Real-Time PCR Protocol Detects Monkeypox Virus

Monkeypox virus, an encapsulated double-stranded DNA virus and member of the Poxviridae family, is responsible for the recent monkeypox outbreak that has been declared a public health emergency of international... Read more

Handheld Diagnostic Lab Offers POC Solution for Future Pandemics

Using swarms of pinhead-sized magnets inside a handheld, all-in-one lab kit, researchers have developed a technology that could significantly increase the speed and volume of disease testing, while reducing... Read more

Image: Measuring levels of three proteins in the blood can aid detection of undiagnosed prediabetes (Photo courtesy of Francis Crick Institute)

Three-Protein Signature Blood Test Can Detect Undiagnosed Prediabetes

Medical and behavioral interventions in individuals with prediabetes are effective in delaying or preventing the onset of type 2 diabetes, but a substantial proportion of people with prediabetes are missed... Read more

Hematology

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Myelodysplastic Syndrome Diagnosed With Peripheral Blood Samples

Myelodysplastic syndromes (MDS) encompass a heterogeneous group of clonal bone marrow neoplasms, with a median age at diagnosis of 70 years. MDS are characterized by recurrent cytogenetic and molecular... Read more

Image: Histopathology of lymph node tissue from a person with idiopathic multicentric Castleman disease. Increased number of blood vessels and smaller germinal centers where immune cells mature in the lymph node, which are two of the pathology features needed to make the diagnosis (Photo courtesy of David Fajgenbaum, MD)

Independent Subtype of Idiopathic Multicentric Castleman Disease Defined

Multicentric Castleman disease (MCD) comprises a heterogeneous group of rare disorders that exhibit generalized symptoms such as swelling of lymph nodes, anemia, fever, and fatigue. Idiopathic multicentric... Read more

Image: The Applied Biosystems 96 well Veriti Thermal Cycler (Photo courtesy of Fisher Scientific)

Accurate Genetic Assay Identifies Human Neutrophil Antigen 2 Deficiency

Human Neutrophil Antigen 2 (HNA-2) is one of the most important neutrophil antigens implicated in a number of human disorders. HNA-2 deficiency or HNA-2 null is a common phenotype observed in 3%–5% of US citizens.... Read more

Image: EnzyPad handheld micro-laboratory will allow blood coagulation monitoring of any patient anywhere in the world (Photo courtesy of Enzyre)

Handheld Micro-Laboratory to Enable Ambulant Multi-Parameter Blood Coagulation Analysis

Hemophilia is a rare genetic disorder that is estimated to affect over 800,000 people worldwide. Those with hemophilia A lack sufficient blood- clotting factor VIII (FVIII) activity, causing them to bleed... Read more

Immunology

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Image: Infections by Epstein-Barr virus usually cause no symptoms, but a growing body of evidence suggests it plays a role in multiple sclerosis (Photo courtesy of Kateryna Kon, MD, PhD)

More Evidence for Epstein - Barr virus' Role in MS Found

The Epstein-Barr virus (EBV) is a common virus that causes glandular fever (infectious mononucleosis), usually in teenagers and young adults. It has been proposed as a possible trigger for multiple sclerosis,... Read more

Immune Reaction to Gut Bacterium May Trigger Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune condition in which the immune system attacks the tissues of the joints, especially in the knees, hands, and wrists. This causes inflammation and painful swelling.... Read more

Image: Immune dysregulation associated with Lyme disease could enable its accurate and prompt treatment (Photo courtesy of Pexels)

Immunoaffinity Technology Distinguishes Between Lyme Disease Infection States and Tracks Treatment Response

Lyme disease is the most prevalent vector-borne disease in the U.S., with an estimated 476,000 annual cases. Current diagnostics for this disease and complicated and rely on indirect methods that suffer... Read more

Macadamia Nut-Specific IgE Levels Predict Anaphylaxis

Proteins residing in tree nuts are mistakenly treated as harmful by the immune system, which then releases antibodies to combat them. Chemical reaction triggers within protein substances, mast cells and... Read more

Microbiology

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Image: Ring-form trophozoites of Plasmodium vivax in a thin blood smear (Photo courtesy of Centers for Disease Control and Prevention)

Immune Regulators Predict Severity of Plasmodium vivax Malaria

Cytokines and chemokines are immune response molecules that display diverse functions, such as inflammation and immune regulation. In Plasmodium vivax infections, the uncontrolled production of these molecules... Read more

Image: The TaqPath Enteric Bacterial Select Panel is CE marked, For In Vitro Diagnostic Use (Photo courtesy of Pexels)

New Test Leverages PCR Technology to Detect Gastrointestinal Bacteria within Two Hours

A new test leverages polymerase chain reaction (PCR) technology to detect common gastrointestinal (GI) bacteria and returns results in about two hours with more than 98% sensitivity and specificity.... Read more

MRSA/SA PCR Rapid Test Quickly Diagnoses Methicillin Resistance at Point of Care

Methicillin-resistant (MRSA) is a major multi-resistant nosocomial pathogen worldwide with the WHO estimating that the mortality rate of patient infection rates is around 50% higher compared with patients... Read more

$Image: Candida auris is a type of fungus and can cause a severe infection in hospital or nursing home patients (Photo courtesy of UCSF Benioff Children\'s Hospital)$

Surveillance Provides Real-Time Information on Candida auris Outbreak

Candida auris is an emerging fungal pathogen causing outbreaks in healthcare facilities. C. auris can cause invasive candidiasis (fungemia) in which the bloodstream, the central nervous system, and internal... Read more

Pathology

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New Molecular Microscopy Tool Uncovers Breast Cancer Spread

Breast cancer commonly starts when cells start to grow uncontrollably, often due to mutations in the cells. Overtime the tumor becomes a patchwork of cells, called cancer clones, each with different mutations.... Read more

Self-Supervised AI Improves Diagnostic Accuracy for Melanoma with Low Pathologist Agreement

Study results on new artificial intelligence (AI) that predicts diagnostic agreement for melanoma highlight the potential of the technology to improve diagnostic accuracy for this deadliest form of skin... Read more

Image: Researchers are using AI techniques to improve pathology workflow (Photo courtesy of Pexels)

Artificial Intelligence Methods Could Replace Histochemical Staining

In the hospital, there is a group of doctors who use tissue samples as "evidence materials", analyze the evidence using knives, slicers and microscopes to extract clues from the tissue samples, and provide... Read more

Image: Claire Carter, Ph.D., an expert in MALDI, led the new research (Photo courtesy of CDI)

Advanced Mass Spectrometry Could Provide Microscopic Clues to Beating Deadly Brain Tumors

Glioblastoma is one of the most difficult cancers, let alone diseases, to treat. The brain tumor presents a median survival rate of just 12 to 15 months. The cancer is especially hard to beat, since it... Read more

Technology

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Image: The Continuity transportable mass spectrometer brings high-sensitivity and large mass range to chemical analysis in the field (Photo courtesy of BaySpec)

Immunoassay, Mini Mass Spec Combined for Malaria Detection

Currently, several different technologies are available for diagnosing malaria, but each has drawbacks. PCR, for instance, is highly sensitive and specific, but it requires upfront sample processing and... Read more

$Image: Researchers are exploring the use of ML for a minimally invasive system to detect Alzheimer\'s disease (Photo courtesy of NIH)$

Biosensing Platform Combined with Machine Learning to Enable Minimally-Invasive Detection of Alzheimer's

Alzheimer's disease is a severe neurodegenerative disorder characterized by progressive memory, cognitive impairment and personality changes, which can further evolve to dementia and death.... Read more

Image: Schematic of the intelligent impedance system, consisting of a parallel impedance cytometry and a machine learning-based detection system (Photo courtesy of Yaxiaer Yalikun, PhD)

Parallel Impedance Cytometry Screens Bacterial Cells in Real Time

Antibiotic-resistant infections are responsible for killing over a million people worldwide every year. Central to managing resistant infections is quickly identifying an appropriate treatment to which... Read more

Image: Light-analyzing ‘lab on a chip’ opens door to widespread use of portable spectrometers (Photo courtesy of Oregon State University)

‘Lab on a Chip’ Paves Way for Use of Portable Spectrometer in Biomedical Analysis

Scientists have developed a better tool to measure light, contributing to a field known as optical spectrometry and resulting in a powerful, ultra-tiny spectrometer that fits on a microchip and is operated... Read more

BioResearch

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Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

A genomics-based blood test can predict likelihood that a baby suffering hypoxia at birth will suffer serious nervous disorders such as cerebral palsy or epilepsy at a later stage of development.... Read more

Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

Cancer researchers developed a 29 gene–based weighted prognostic score for predicting event-free survival and overall survival of patients suffering from diffuse large B-cell lymphoma (DLBCL).... Read more

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction.... Read more

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. Methods currently used to diagnose... Read more

Industry

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Image: Nanōmix eLab is a mobile, hand-held immunoassay and chemistry diagnostic system (Photo courtesy of Nanomix)

Mast Group Enters into Multi-Country Distribution Agreement for Nanomix's eLab System

Mast Group Limited (Liverpool, UK) and Nanomix (Emeryville, CA, USA) have entered into a multi-region distribution agreement wherein Mast will market and distribute the Nanōmix eLab system in the UK, Germany,... Read more

Image: Numares AXINON System (Photo courtesy of Numares)

AI-Enabled Diagnostic Testing Could Become More Accurate and Reliable than Current Tests

An expanded collaboration between two industry leaders will pave the way for the development of AI-enabled diagnostic testing that is more accurate and reliable than current U.S. tests for patients with... Read more

Image: The global infectious respiratory disease diagnostics market is expected to reach USD 43.6 billion by 2030 (Photo courtesy of Pexels)

Global Infectious Respiratory Disease Diagnostics Market Driven by New Multiplex PCR Tests and POC Products

The global infectious respiratory disease diagnostics market size is expected to reach USD 43.6 billion by 2030, driven by an increase in the prevalence of infectious respiratory diseases and initiatives... Read more

Image: The Binding Site has entered into an agreement to combine with Thermo Fisher Scientific (Photo courtesy of The Binding Site Group)

UK's Binding Site to Be Acquired by Thermo Fisher for USD 2.6 Billion

Thermo Fisher Scientific Inc. (Waltham, MA; USA) has entered into a definitive agreement to acquire The Binding Site Group (Birmingham, UK) in an all-cash transaction valued at USD 2.6 billion.... Read more

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