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Image: A histopathology of pancreatic adenocarcinoma, where the adenocarcinoma has wrapped around a nerve (center) (Photo courtesy of Johns Hopkins Medicine).

Pancreatic Cancer Potentially Diagnosed by ctDNA

Pancreatic cancer remains a devastating disease, with the diagnosis typically being made late. Circulating Tumor DNA (ctDNA) has shown promise as a screening test for various tumor types. Read more
21 Jun 2017 | Molecular Diagnostics
Image: A histopathology of lung tissue from a patient with hemosiderosis: in the alveolar spaces and in the septa are hemosiderin-laden macrophages (Photo courtesy of Getty Images).

Hemosiderosis Screening Assessed for Multiple Transfusion Patients

Hemosiderosis is a type of secondary iron overload resulting from multiple blood transfusions and the leading cause of death in transfusion-dependent patients with thalassemia. Read more
20 Jun 2017 | Hematology
Image: The Quo-Test HbA1c fully automated analyzer uses patented boronate fluorescence quenching technology to measure glycated hemoglobin from a 4 μL sample taken from a finger prick or venous whole blood (Photo courtesy of EKF Diagnostics).

POC Analyzer Compared with HPLC Method

The measurement of the glycated fraction of hemoglobin (HbA1c) has been recommended to diagnose diabetes, in addition to monitoring glycemic control. Read more
20 Jun 2017 | Clinical Chemistry
Image: Dr. John Lewis, left, who developed the Extracellular Vesicle Fingerprint Predictive Score (EV-FPS) test, works with a graduate student (Photo courtesy of University of Alberta).

Blood Test Predicts Aggressive Prostate Cancer

Current tests such as the prostate specific antigen (PSA) and digital rectal exam (DRE) often lead to unneeded biopsies and more than 50% of men who undergo biopsy do not have prostate cancer, yet suffer the pain and side effects of the procedure such as infection or sepsis. Read more
20 Jun 2017 | Molecular Diagnostics
Image: A new report suggests utilization of trained personnel and evaluation of tests will help ensure that best-quality tests are ordered and interpreted correctly to benefit patient care (Photo courtesy of the American Society for Microbiology).

Report Discusses POC Testing and Changing Paradigms

The American Academy of Microbiology has released a new report on the role of the role of point-of-care (POC) and near-patient testing in changing diagnostic paradigms in microbiology. Read more
20 Jun 2017 | Microbiology
Image: Research shows Zika fever symptoms are often misdiagnosed due to its nonspecific clinical symptoms, so a highly accurate diagnostic assay for Zika virus is especially important (Photo courtesy of the American Society for Microbiology).

Assay Detects Zika in Semen Samples

Researchers have found that an available clinical assay could reliably detect Zika virus from semen samples spiked with low levels of recombinant Zika virus. Read more
19 Jun 2017 | Microbiology
Image: The new device combines two sensing methods, which had not until this time been able to be used together. It uses a 3D multi-layer nanocavity in a nanocup array, and it uses plasmonic sensing (Photo courtesy of University of Illinois).

Sensor Technology May Improve Cancer Diagnosis

Researchers have developed a plasmonic sensor that could provide reliable early detection of biomarkers for many forms of cancer and eventually for other diseases. Read more
19 Jun 2017 | Lab Tech.
Image: The UrNCollect device is designed for use with the SelectMDx in vitro diagnostic (IVD) PCR test kit for prostate cancer (Photo courtesy of MDxHealth).

New Diagnostic Products Detect Prostate Cancer

A novel sample collection device was designed to support a urine-based non-invasive "liquid biopsy" molecular diagnostic test that determines the risk for developing high-grade prostate cancer. Read more
19 Jun 2017 | Lab Tech.

Channels

Clinical Chemistry

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Cardiac Troponin Test Uses Single Molecule Counting Technology
Thyroid Disorders Affect Circulating TRAIL Levels
Baby Teeth Reveal Association Between Autism and Metals
Image: The Videssa Breast protein biomarker blood test for breast cancer evaluates 11 serum protein biomarkers and 33 tumor-associated autoantibodies (Photo courtesy of Provista Diagnostics).

Blood Test Offers Improved Breast Cancer Detection

Breast cancer is predicted to be the second leading cause of cancer deaths in the USA women. Approximately 232,000 cases of invasive breast cancer and 60,000 cases of ductal carcinoma in situ (DCIS) are... Read more

Molecular Diagnostics

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Genetic Test Identifies Risk of Anal Cancer
Sequencing Approach to Detect Genomic Alterations
Genetic Mutation Identified for Childhood Kidney Cancer
Image: Scientists found that by testing for 19 new genetic factors in addition to the 25 risk genes already known, they could identify the 1% of men at highest risk of testicular cancer (Photo courtesy of Shutterstock).

Biomarkers Show Highest Risk for Testicular Cancer

Results of a large genome-wide association study (GWAS) have enabled the identification of 19 new risk loci and potential regulatory mechanisms influencing the susceptibility to testicular germ cell cancer.... Read more

Hematology

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Apheresis System with Secondary Devices Evaluated
Routine Blood Tests Could Help Predict Fitness Changes
Molecular Test Predicts Blood Cancer Patient Survival
Image: Research shows high blood platelet count is a strong predictor of cancer (Photo courtesy of Getty Images).

Elevated Blood Platelet Count Predicts Cancer

The most common route to cancer diagnosis follows the development of symptoms, and definitive diagnosis by biopsy and access to specialist care often rely on a primary care physician to recognize the possibility... Read more

Immunology

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Multiplex Immunoassay Diagnoses Toxoplasmosis and Rubella
Panel Developed for Immunophenotyping Lymphocytes
Strip Test Enables Home Monitoring of Heart Condition
Image: New research shows changes in immune activity appear to signal a growing brain tumor up to five years before symptoms begin (Photo courtesy of iStock).

Immune System Changes Signal Early Brain Cancer

Glioma is a heterogeneous primary malignant brain tumor with a median survival time, for the most common adult subtype, glioblastoma, of only 14 months. Changes in immune activity appear to signal a growing... Read more

Microbiology

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New Test Accurately Detects Latent HIV
Biosensor Technology Enables Rapid Detection of Flu Virus
Combination of Antibiotics Can Eradicate Super Pathogens
Image: The eazyplex MRSA test system is designed for the detection of S. aureus and MRSA (pictured) in invasive samples such as pleural and synovial fluid (Photo courtesy of MNT).

LAMP Assay Validated for MRSA in Invasive Samples

Staphylococcus aureus is a leading cause of bone and joint infections and one of the most common causative pathogens of bacterial pneumonia in children. An increased risk of mortality from invasive staphylococcal... Read more

Pathology

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Heterogeneity Influences Cancer Immunohistochemistry Results
Biomarkers Revealed for Cognitive Impairment in PD
Pathogens Help Diagnose Fatty Liver Disease
Image: A new study determined intestinal fungi may contribute to the development of alcoholic liver disease (Photo courtesy of Shutterstock).

Intestinal Fungi Contribute to Alcoholic Liver Disease

Chronic liver disease with cirrhosis is the 12th leading cause of death in the USA, and alcoholic liver disease accounts for approximately half of all cirrhosis deaths. Chronic alcohol consumption is associated... Read more

Lab Tech.

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Graphene-Based Sensor Helps Predict Asthma Attacks
Novel Device Reduces Blood Draw Contamination
Smart Pills Offer Diagnostic Tool for Gut Disorders
Image: Determining which stain on these paper filters (top row) is from blood (C) rather than coffee (A) or tea (B) is easier with the new, more selective artemisinin-luminol chemiluminescence test for forensic bloodstain detection (bottom row) (Photo courtesy of ACS).

Antimalarial Compound Improves Forensics of Bloodstains

Forensic investigators often use a luminol chemiluminescence test to detect latent bloodstains at crime scenes. Now, researchers have found that combining luminol with the antimalarial drug artemisinin,... Read more

Industry News

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Global Robotic Lab Systems Market Reaches USD 8.8 Billion
Sysmex Corporation to Acquire Oxford Gene Technology
Stago Group Acquires HemoSonics
Image: Grifols and Beckman Coulter have entered into an exclusive agreement for the worldwide distribution of Grifols’ hemostasis instruments, reagents and consumables (Photo courtesy of iStock).

Grifols and Beckman Coulter Enter Distribution Agreement

Healthcare company Grifols (Barcelona, Spain), which produces plasma-derived medicines and also develops diagnostic solutions, and Beckman Coulter Inc. (Brea, CA, USA), a provider of diagnostics solutions,... Read more

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