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Trending Articles

Portable, Sample to Answer PCR Device Delivers Accurate Results in 30 Minutes at Point of Need

Several Biomarkers Predict Progression of SARS-CoV-2 Infection

Sakura Finetek Launches New Advanced Staining System

AI-Based Pathology Diagnosis Tool Detects Seven Types of Gastric Cancer

Medica Labmed Forum Presents Innovations from the World of Laboratory Medicine

Molecular Endometrial Cancer Test Developed

Breakthrough Method Diagnoses Parkinson’s from Skin Swabs in Three Minutes

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Portable, Sample to Answer PCR Device Delivers Accurate Results in 30 Minutes at Point of Need

Biohit’s Innovative GastroPanel Quick Test Receives CE Mark

New Urinalysis Solution Improves Laboratory Workflow by Reducing Manual Reviews and Sample Processing Time

One-Time Blood Test Predicts Which Hospitalized COVID-19 Patients Will Grow Worse

Health Care Professionals Showed Increased Interest in POC Technologies During Pandemic, Finds Study

Set Up Reserve Lab Capacity Now for Faster Response to Next Pandemic, Say Researchers

Blood Test Performed During Initial Infection Predicts Long COVID Risk

One-Time Blood Test Predicts Which Hospitalized COVID-19 Patients Will Grow Worse

IL-1RA Antibodies in Myocarditis After SARS-CoV-2 Vaccination

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Events

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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

05 Oct 2022 - 07 Oct 2022

JFBM 2022 - Journées Francophones de Biologie Médicale

05 Oct 2022 - 07 Oct 2022

54th National Congress of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC)

05 Oct 2022 - 09 Oct 2022

35th IFBLS World Congress 2022 – International Federation of Biomedical Laboratory Science

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Novel Endoscopic Hemostasis System Improves Visibility and Controls Upper GI Bleeding

Ultraflexible, Gas-Permeable Thermistors to Pave Way for On-Skin Medical Sensors and Implantable Devices

Fecal Transplant by Capsule as Effective as Colonoscopy for CDI

First-Ever Spinal Surgical Hand-Held Robot Makes Worldwide Debut

AI-Guided Screening Uses ECG Data to Detect Hidden Risk Factor for Stroke

Simple Blood Draw Could Revolutionize Early Breast Cancer Detection

Image: Special blood test could determine if patient has early stage breast cancer and if the cancer is unlikely to return (Photo courtesy of USC)

Scientists have found indications that a special blood test called a liquid biopsy could determine whether a patient has breast cancer at its early stage and if that cancer is unlikely to return. Read more
03 Oct 2022

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New Avenues for Use of Single-Molecule Detection Assays in Clinical Diagnosis

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Single Blood Test Enables Early Detection of Multiple Cancer Types

30 Sep 2022

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Industry Spotlight

Global Infectious Disease IVD Market Dominated by Molecular Diagnostics Technology

The global infectious disease in vitro diagnostics (IVD) market stood at USD 113.7 billion in 2021 and is expected to grow at a CAGR of -7. Read more
28 Sep 2022

Mindray Showcases Hematology Innovations at ISLH 2022

Mindray (Shenzhen, China) showcased its hematology innovations and academic achievements to medical experts from Europe and around the world at the International Symposium on Technological Innovations in Laboratory Hematology (ISLH 2022) held between September 8-10 in Bologna, Italy. Read more
27 Sep 2022

Pluslife and FIND Set Collaborate to Empower LMICs with Next-Gen POC Molecular Testing in Women’s Healthcare

Guangzhou Pluslife Biotechnology (Pluslife, Guangzhou, China) and the Foundation for Innovative New Diagnostics (FIND, Geneva, Switzerland) have entered into a strategic collaboration to support low- and middle-income countries (LMICs) in the development of diagnostic tools for women’s healthcare by providing access to next generation point of care (POC) molecular testing technology. Read more
19 Sep 2022

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In Other News

Image: The scanning electron microscope image shows SARS-CoV-2 (yellow) (Photo courtesy of NIAID-RML)

Blood Test Performed During Initial Infection Predicts Long COVID Risk

A blood test taken at the time of COVID-19 infection could predict who is most likely to develop long COVID, suggests a new small-scale study. Read more
30 Sep 2022 | COVID-19

Image: BRAF, a protein involved in sending signals inside cells which are involved in directing cell growth, is mutated in some human cancers (Photo courtesy of www.123rf.com)

Novel Biomarker Predicts Response to Therapy in Patients with a Rare Form of Metastatic Colorectal Cancer

Cancer researchers have identified a biomarker that predicts response of patients with microsatellite stable BRAF V600E metastatic colorectal cancer (MSS mCRC) to treatment with combined anti-BRAF/EGFR therapy. Read more
29 Sep 2022 | Molecular Diagnostics

Image: Colored scanning electron micrograph (SEM) of a bladder cancer cell. Its several long cytoplasmic projections may enable it to be motile (Photo courtesy of Steve Gschmeissner)

CDH1 Overexpression Predicts Early-Stage Bladder Cancer

Bladder cancer (BC) is a serious public health problem, but effective biomarkers for BC diagnosis, particularly in the early stage, are still lacking. Read more
29 Sep 2022 | Molecular Diagnostics

Image: A new biosensor could precisely diagnose brain cancer from minute blood sample (Photo courtesy of Unsplash)

Biosensor Detects Brain Tumors with Less Than a Drop of Blood

Despite significant advances, mortality from brain tumors remains high with five-year survival rates of 36%. Read more
29 Sep 2022 | Molecular Diagnostics

Image: Interest in POC technologies increased among health care professionals during pandemic (Photo courtesy of UMass Chan Medical School)

Health Care Professionals Showed Increased Interest in POC Technologies During Pandemic, Finds Study

Few studies have looked at factors affecting adoption of point-of-care technologies (POCTs) among health care professionals. Read more
29 Sep 2022 | COVID-19

Image: Researchers have suggested effective preparation for the next pandemic (Photo courtesy of Cultura RM Exclusive/Matt Lincoln)

Set Up Reserve Lab Capacity Now for Faster Response to Next Pandemic, Say Researchers

The lack of early COVID-19 PCR testing capacity had a knock-on effect on other health services in 2020. Read more
29 Sep 2022 | COVID-19

Image: Photomicrograph of the bacterium, Bacteroides hypermegas after being cultured in a thioglycollate medium, for a 48 hour time period. Members of the genus Bacteroides are anaerobic, Gram-negative bacteria, which are mainly found in the intestine, as normal flora (Photo courtesy of Dr. V. R. Dowell, Jr.)

Elevated Antibody Levels Identified in Chronic Fatigue Syndrome Patients

Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) experience a lingering fatigue that can drastically impair their social and work life. Read more
28 Sep 2022 | Immunology

Image: Mindray ToRCH reagents deliver excellent seroconversion sensitivity (Photo courtesy of Mindray)

Mindray Launches High-Sensitivity and High-Specificity ToRCH Panel

Mindray (Shenzhen, China) has launched the ToRCH Panel that provides high-quality assays to meet different clinical needs. Read more
28 Sep 2022 | Molecular Diagnostics

$Image: Histopathology of Patient with Crohn\'s disease showing evidence of an epithelioid nonnecrotizing granuloma (Photo courtesy of Catherine E. Hagen, MD and Luisa Ricaurte Archila, MD)$

Longitudinal Laboratory Data Predicts Complication in Crohn’s Disease Patients

Stenosis, fistulization, and perforation of the bowel are severe outcomes which can occur in patients with Crohn’s disease. Read more
27 Sep 2022 | Pathology

Image: The Dako Autostainer Link 48 ensures optimal staining results and offers a high slide and reagent capacity (Photo courtesy of Agilent)

PD-L1 Expression Associated With Poorer Survival in Anal Squamous Cell Carcinoma

Although anal squamous cell carcinoma (ASCC) is a rare malignancy, making up only 0.5% of all cancer cases in the USA, disconcertingly, the annual incidence continues to rise both globally and in the USA. Read more
27 Sep 2022 | Pathology

Image: Tiny nets woven from DNA strands cover SARS-CoV-2 spike proteins and give off glowing signal (Photo courtesy of Xing Wang)

Low-Cost COVID-19 Testing Platform Combines Sensitivity of PCR and Speed of Antigen Tests

DNA is best known for its genetic properties, but it also can be folded into custom nanoscale structures that can perform functions or specifically bind to other structures much like proteins do. Read more
27 Sep 2022 | COVID-19

Image: IL-1RA antibody levels measured as a biomarker in young males with myocarditis after SARS-CoV-2 vaccination (Photo courtesy of Patrice Wendling)

IL-1RA Antibodies in Myocarditis After SARS-CoV-2 Vaccination

Myocarditis associated with messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) predominantly affects male adolescents and young male adults (14 to <30 years of age) and typically occurs after receipt of the second vaccine dose. Read more
26 Sep 2022 | Pathology

Channels

Clinical Chem.

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Image: The Article Transfer Service is designed to help manuscripts find the right journal faster (Photo courtesy of Elsevier)

Article Submission Process Streamlined for Clinica Chimica Acta and Related Journals

Submitting an article for a scientific publication is an essential step in the research process, but finding the right journal can be challenging. Often authors' first choice of journal turns out not to... Read more

Image: High-sensitivity cardiac troponin I: relying on the sex-specific 99th percentile upper reference limit of cardiac troponin may incorrectly suggest myocardial infarction (MI) in older adults with suspected heart attacks (Photo courtesy of Blood Tests in London)

Age Alters Diagnostic Performance of Cardiac Troponin

The guideline-recommended thresholds for increased high-sensitivity cardiac troponin I (hs-cTnI), indicating myocardial injury and potential infarction, performed at a similar sensitivity around 80% in... Read more

Low Testosterone Levels Tied to More Severe COVID in Men

The COVID-19 pandemic has exacted a heavy toll on public health. Male sex is associated with severe COVID-19. It is not known whether the risk of hospitalization differs between men with hypogonadism,... Read more

mage: The AU560 automatic enzymatic analyzer (Photo courtesy of Sysmed Lab Europe)

Osteopontin and Osteoprotegerin Investigated In Peripheral Artery Disease

Peripheral artery disease (PAD) is one of the many complications of systemic atherosclerosis and it is accompanied by high rates of cardiovascular diseases (CVD) morbidity and mortality.... Read more

Molecular Diagnostics

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Image: Metabolomic profiling reveals risk of multiple diseases all at once (Photo courtesy of BIH)

Single Blood Test Predicts Risk of Multiple Diseases Simultaneously Using AI

Prevention is better than cure. To prevent diseases from occurring in the first place, it is important to identify those individuals who are at particularly high risk as early as possible.... Read more

Image: Blood test before CAR T-Cell treatment can identify patients likely to develop neurotoxicity (Photo courtesy of Unsplash)

Simple Blood Test Prior to CAR T-Cell Therapy Could ID Patients at Risk for Neurotoxicity

Neurologic complications are common following treatment with chimeric antigen receptor (CAR) T cells, with an estimated 40-60% of patients developing immune effector cell–associated neurotoxicity syndrome (ICANS).... Read more

Image: Endometriosis: schematic illustration of the uterus and female reproductive system diseases (Photo courtesy of www.123rf.com)

A Single-Cell RNA-Sequencing-Based Non-Invasive Screening Tool for Endometriosis

Results presented in a recent paper lay the ground work for using menstrual effluent (ME) as an effective screening tool for identifying endometriosis in patients with chronic symptoms suggestive of this disorder.... Read more

Bioperfectus Launches New MPXV Detection Kits for Better Control of Monkeypox Virus Outbreak

Since January 2022, cases of monkeypox have been reported across almost 60,000 in 102 countries and regions. According to data presented by WHO, about 99% of cases in 95 locations have not been historically... Read more

Hematology

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Image: Photomicrograph of Hodgkin lymphoma (HL) from a fine needle aspirate of a lymph node. The micrograph shows a mixture of cells common in HL: Eosinophils, Reed-Sternberg cells, Plasma cells, and Histocytes (Photo courtesy of Nephron)

Inherited Genetic Variants Increase Risk of Hodgkin Lymphoma

Hodgkin lymphoma (HL) is a type of lymphoma, in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in... Read more

Image: The STA R MAX is a hemostasis analyzer for high-volume and reference laboratories performing routine and specialty assays (Photo courtesy of Stago)

D-Dimer and Thrombosis Risk in Adult Acute Lymphoblastic Leukemia

D-dimer is a marker of fibrinolysis harkening the presence of or risk for thrombosis, and it has been found to be a powerful predictor of thrombosis in solid cancers and acute myeloid leukemia (AML).... Read more

Image: Preventing and treating thalassemia with genomics (Photo courtesy of BGI Genomics)

NGS Blood Test Qualitatively Detects Thalassemia Mutations

Thalassemia is an inherited blood disorder caused by an abnormal hemoglobin molecule, which inhibits the body’s ability to produce hemoglobin or red blood cells. Thalassemia occurs in approximately 4.... Read more

Image: Bone marrow aspirate from a patient with Classic Hodgkin lymphoma showing large multinucleated Reed-Sternberg cells. “Hodgkin cells” are mononuclear while “Reed-Sternberg” cells are multinucleate forms (Photo courtesy of Nidia P. Zapata, MD and Espinoza-Zamora Ramiro).

Flow Cytometry Of Reactive T-Cells Differentiates Lymphoproliferative Diseases

Classic Hodgkin lymphoma (cHL) is an unusual form of lymphoma characterized by a small number of neoplastic Hodgkin and Reed–Sternberg (HRS) cells in an extensive inflammatory background and about 90%... Read more

Immunology

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Image: ALEX2 is a state-of-the-art multiplex ELISA test based on proven immunoassay chemistry and detection methods (Photo courtesy of Macro Array Diagnostics)

Diagnostic Assay Identifies Which Species Patients with Fish Allergy Can Tolerate

Fish allergy is an immune hypersensitivity to proteins found in fish. Symptoms can be either rapid or gradual in onset. The latter can take hours to days to appear. The former may include anaphylaxis,... Read more

Image: Experimental test promises to predict side-effects and cancer’s return in patients treated with immunotherapy (Photo courtesy of National Cancer Institute)

Single Test Predicts Cancer Recurrence and Side-Effects of Immunotherapy

Patients treated with immunotherapies – which harness the immune system to attack cancer cells – are likely to see their cancer recur or have severe side effects. To spare normal cells from autoimmune... Read more

Image: The AutoDELFIA 1235 is an automatic immunoassay system (Photo courtesy of PerkinElmer Life Sciences)

High-Capacity Serological Assay Developed for Celiac Disease

Celiac disease is a chronic inflammatory disorder of the small intestinal mucosa occurring in genetically predisposed individuals exposed to dietary gluten proteins of wheat (gliadin and glutenin), barley... Read more

Image: The BioIC Allergen Specific-IgE Detection Kit-AD 40 panel (Photo courtesy of Agnitio Science and Technology).

Cord Blood IgE Levels Tied To Allergy, Asthma Rates

The rising prevalence of allergic diseases worldwide represents an important health problem. Early identification of children at high risk of allergic diseases could be helpful for physicians to recommend... Read more

Microbiology

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$Image: Candida auris is a type of fungus and can cause a severe infection in hospital or nursing home patients (Photo courtesy of UCSF Benioff Children\'s Hospital)$

Surveillance Provides Real-Time Information on Candida auris Outbreak

Candida auris is an emerging fungal pathogen causing outbreaks in healthcare facilities. C. auris can cause invasive candidiasis (fungemia) in which the bloodstream, the central nervous system, and internal... Read more

Image: The XN-31 hematology analyzer on which the prototype for malaria detection was based (Photo courtesy of Sysmex Corporation)

Haematology Analyzer Prototype Tested for Field Malaria Surveillance

Simple and accurate diagnosis is a key component of malaria control programmes. Microscopy is the current gold standard, however it requires extensive training and the results largely rely on the skill... Read more

Image: The Promega Maxwell 16 automated purification of genomic DNA, RNA or recombinant Proteins from a wide range of sample types (Photo courtesy of Fischer Scientific).

Test Combination Detects Latent Leishmaniasis Infection

After infection with Leishmania infantum cutaneous or visceral leishmaniasis can develop, but in most cases the host becomes an asymptomatic carrier of the parasite. This key population of individuals... Read more

Mechanism Behind Deadly Fungal Infection with Influenza or Covid-19 Deciphered

Every year, hundreds of thousands of people worldwide end up in intensive care with influenza or Covid-19. About 15% of them develop an additional lung infection with the common fungus Aspergillus (aspergillosis).... Read more

Pathology

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Image: A diagnostic tool under development has succeeded in expanding its AI detection to seven types of gastric cancer (Photo courtesy of Evident)

AI-Based Pathology Diagnosis Tool Detects Seven Types of Gastric Cancer

There is increasing demand for diagnostic tools that can help reduce the workload of pathologists. Now, researchers developing an AI-based pathology diagnostic tool have succeeded in expanding its AI detection... Read more

Image: Parkinson’s breakthrough can diagnose disease from skin swabs in 3 minutes (Photo courtesy of University of Manchester)

Breakthrough Method Diagnoses Parkinson’s from Skin Swabs in Three Minutes

Sebum is an oily secretion from sebaceous glands under the skin which are connected to the endocrine system. Now, scientists have found a new method to detect Parkinson’s disease by analyzing sebum with... Read more

Sakura Finetek Launches New Advanced Staining System

Sakura Finetek Europe (The Netherlands) has launched its newest solution Tissue-Tek Genie, an advanced staining system. The Tissue-Tek Genie Advanced Staining System is the first and only fully automated,... Read more

AI-Powered Pathology Platform Advances Diagnosis of Prostate, Breast and Gastric Cancer

A transformative cancer diagnostics platform now offers new detection capabilities and a broad feature set to support pathologists and providers with AI-insights that help improve the quality and accuracy... Read more

Technology

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Image: OneDraw Blood Collection Device significantly reduces obstacles for drawing blood (Photo courtesy of Drawbridge Health)

Near Pain-Free Blood Collection Technology Enables High-Quality Testing

Blood tests help doctors diagnose diseases and conditions such as cancer, diabetes, anemia, and coronary heart disease, as well as evaluate organ functionality. They can also be used to identify disease... Read more

Image: MIC could change the landscape of the clinical lab testing field (Photo courtesy of OEA)

Microchip Imaging Cytometry Makes Laboratory Testing More Economical, Easy-to-Use and Accessible

The economic globalization and the aging population of many countries in the world generate an enormous need for rapid and cost-effective point-of-need laboratory tests. Over the past two years, the entire... Read more

Image: Associate Professor Yuze “Alice” Sun is creating a wearable device for rapid gas analysis (Photo courtesy of The University of Texas at Arlington)

Wearable Rapid Gas Analyzer Could Detect Illness Immediately

Advancements in micro-gas chromatography in the past 20 years have demonstrated great potential for the development of powerful portable gas analysis devices. But it remains a challenge to achieve efficient... Read more

Ultracompact Microscope Enables High-Performance Imaging for Biomedical Diagnosis

Metalens technology opens a new way to achieve ultracompact and lightweight optical imaging systems. A metalens is a kind of metasurface composed of subwavelength units with powerful capability for manipulating... Read more

BioResearch

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Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

A genomics-based blood test can predict likelihood that a baby suffering hypoxia at birth will suffer serious nervous disorders such as cerebral palsy or epilepsy at a later stage of development.... Read more

Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

Cancer researchers developed a 29 gene–based weighted prognostic score for predicting event-free survival and overall survival of patients suffering from diffuse large B-cell lymphoma (DLBCL).... Read more

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction.... Read more

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. Methods currently used to diagnose... Read more

Industry

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Image: AACC has released a POCT guide for non-laboratorians (Photo courtesy of Pexels)

AACC Releases Guidelines on Point-of-Care Testing for Non-Laboratorians

Point-of-care testing (POCT), or near-patient testing, is diagnostic testing conducted close to the patient, often by clinical personnel outside of the laboratory. POCT is regularly performed by personnel... Read more

Image: The global diagnostic labs market is projected to touch USD 515 billion by 2028 (Photo courtesy of Pexels)

Global Diagnostic Labs Market Driven by Increased POCT Testing and Smart Portable Devices

Clinical diagnostics are beneficial for diagnosing prevalent chronic diseases and are valuable in disease prevention, detection, and treatment. Clinical diagnostics help identify early warning signs and... Read more

Image: The global PCR and real-time PCR testing market is expected to approach USD 25 billion in 2026 (Photo courtesy of Pexels)

Global PCR and Real-Time PCR Testing Market Driven by Need for Early Disease Detection

The polymerase chain reaction (PCR) and real-time polymerase chain reaction testing market consists of sales of PCR and real-time PCR testing services and related products. The real-time RT-PCR technique... Read more

Image: Presenting the newest trends in in-vitro diagnostics (Photo courtesy of MEDICA)

Medica Labmed Forum Presents Innovations from the World of Laboratory Medicine

Since 2017, the field of laboratory medicine has been represented by a scientific event of high-caliber experts at internationally leading trade fair MEDICA (Düsseldorf, Germany). The event takes place... Read more

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