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In Other News

Image: The Pathfinder fully automated cell reader-analyzer system allows for optimized multimodal scanning, cell detection and analysis (Photo courtesy of IMSTAR).

Generic Test Developed for Early Detection of Cancer

Cancer is one of the leading causes of death worldwide. Early detection of cancer significantly raises the chances for an effective treatment. Read more
07 Nov 2018 | Pathology
Image: Next-generation Influenza A & B 2 and Strep 2 molecular assays for point-of-care cleared by FDA for use on the Abbott ID Now platform (Photo courtesy of Abbott Diagnostics).

Molecular Influenza and Streptococcus Tests Get FDA Clearance

Each year, a combination of influenza A and B virus strains circulate within the USA. The burden of influenza in the USA is currently estimated to be 9 to 36 million cases per year. Read more
07 Nov 2018 | Microbiology
Image: The QX200 Droplet Digital PCR System provides absolute quantification of target DNA or RNA molecules (Photo courtesy of Bio-Rad Laboratories).

HPV DNA Test Monitors Remission in Oral Cancer

A blood-based method has been developed to test patients with human papillomavirus-associated oral cancers for signs of remission or recurrence. Read more
06 Nov 2018 | Pathology
Image: The WITec alpha 300AR confocal Raman microscope (Photo courtesy of WITec).

Resistance of Tumor Cells to Cancer Drugs Detected

Acquired resistance is developing during treatment of cancer patients who were initially responding to the therapy. Read more
06 Nov 2018 | Pathology
Image: The Cap‐Score detects and analyzes localization patterns using fluorescent microscopy to distinguish fertile from infertile sperm cells (Photo courtesy of Androvia LifeSciences).

New Test Measures Men's Fertility

Male fertility is a serious and growing concern globally. Yet, the field of andrology faces critical gaps in diagnostic technologies and knowledge, affecting scientific advancement as well as clinical management by both reproductive endocrinologists and urologists. Read more
06 Nov 2018 | Lab Tech.
Image: The Cobas 6000 analyzer series for clinical chemistry and immunochemistry assays (Photo courtesy of Roche Diagnostics).

Plasma Lactate Measurement Used to Test Variability

Clinical laboratories are required to adhere to manufacturers’ recommended sample handling instructions as part of their compliance with accreditation certification. Read more
05 Nov 2018 | Clinical Chemistry
Image: The i-STAT cardiac troponin I assay; healthcare professionals can obtain quantitative measurement of cardiac troponin I (cTnI) in ten minutes without leaving the patient\'s side (Photo courtesy of Abbott Point of Care).

Novel POC Troponin Assay Rules Out Acute MI

More than seven billion diagnostic tests are run in the USA each year to help physicians make accurate, timely decisions about a person's medical treatment. Read more
05 Nov 2018 | Clinical Chemistry
Image: Researchers have developed the first diagnostic platform that can simultaneously screen for all known human pathogenic bacteria, as well as markers for virulence and antibiotic resistance (Photo courtesy of Columbia University).

Ultrasensitive Screening Platform Detects Pathogenic Bacteria

A diagnostic platform has been developed that significantly increases the sensitivity of high-throughput sequencing for detection and characterization of bacteria, virulence determinants, and antimicrobial resistance (AMR) genes. Read more
05 Nov 2018 | Molecular Diagnostics
Image: The T-SPOT.TB test is a unique, single-visit blood test for tuberculosis (TB) screening, also known as an interferon gamma release assay (IGRA) (Photo courtesy of Oxford Immunotec).

LTB Infection Estimated with Interferon-γ Release Assay

Latent tuberculosis (LTB), also called latent tuberculosis infection (LTBI) is when a person is infected with Mycobacterium tuberculosis, but do not have active tuberculosis. Read more
01 Nov 2018 | Microbiology
Image: The HiSeq 2500 System is a powerful high-throughput sequencing system (Photo courtesy of Illumina).

Functional Genomic Landscape of AML Analyzed

Acute myeloid leukemia is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells. Read more
01 Nov 2018 | Hematology
Image: The FECPAKG2 modernizes the traditional microscope-based parasite testing method by replacing it with an Internet connected, image based kit (Photo courtesy of Techion).

Detection Method for Soil-Transmitted Helminth Eggs Optimized

Soil-transmitted helminths are a group of intestinal parasitic worms that infect humans through contact with infectious stages present in the soil. Read more
31 Oct 2018 | Microbiology

Channels

Clinical Chemistry

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Noninvasive Blood Glucose Test Evaluated for Accuracy
Kidney Function Decline Linked with Inflammatory Marker Levels
Kidney Disease Biomarker May Indicate Lung Problems
Image: The Dade Behring BN100 nephelometer (Photo courtesy of Siemens Healthineers).

Chronic Inflammation Linked to Risk for Alzheimer's Disease

While it has been widely shown that possessing the apolipoprotein E4 (ApoE4) gene is the major genetic risk factor of Alzheimer's disease (AD), not all ApoE4 carriers develop AD. It is likely that a complex... Read more

Molecular Diagnostics

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CD MicroRNA Marks Subtypes with Differing Outcomes
Novel Technology Enables Detection of Early-Stage Cancer
Epigenomic Method Developed to Detect Pancreatic Cancer
Image: A photomicrograph from a prostate biopsy of prostatic adenocarcinoma, conventional (acinar) type, the most common form of prostate cancer (Photo courtesy of Nephron).

Fatal Prostate Cancer Differentiated from Manageable Cancer

Human prostate cancers display numerous DNA methylation changes compared to normal tissue samples. However, definitive identification of features related to the cells’ malignant status has been compromised... Read more

Hematology

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Prognostic Value of Blood Cell Counts Investigated
Multiple Myeloma Subtypes Linked to Patient Ancestry
Molecular Diagnostics Prevents Malaria in Blood Banks
Image: A blood smear from a 68-year-old woman with a 13-year history of polycythemia vera and there are three red blood cell precursors present and slight to moderate anisopoikilocytosis (Photo courtesy of The Armed Forces Institute of Pathology).

Myeloproliferative Neoplasms Fall into Genetic Subgroups

Myeloproliferative neoplasms are a group of chronic blood cancers associated with a risk of bleeding and blood clots, but they can also progress to more advanced disease, including leukemia.... Read more

Immunology

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Link Between Gut Flora and MS Discovered
Biomarkers Correlated with Idiopathic Inflammatory Myopathy
Tumor Markers Associated with H. Pylori Infection
Image: Immunohistochemistry staining of Helicobacter pylori on Formalin-Fixed Paraffin-Embedded (FFPE) Infected Stomach Tissue (Photo courtesy of Bio SB).

Stomach Cancer Bacterium Increases Colorectal Cancer Risk

A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans. An association of the bacteria Helicobacter pylori, the primary... Read more

Microbiology

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New Techniques Can Detect Lyme Disease Earlier
Study Shows Zika Virus Persists in Body Fluids
Human Pegivirus Identified in Encephalitis Patients
Image: Deeplex-MycTB deep sequencing test analyses a wide panel of target genes in the bacteria and can identify resistance to over a dozen antibiotics simultaneously (Photo courtesy of Genoscreen).

Multidrug-Resistant TB Outbreak Undetected by Standard Tests

Rapid diagnosis of Mycobacterium tuberculosis resistant to anti-tuberculosis drugs is essential to prevent further acquisition of drug resistance, high morbidity and mortality, and unabated transmission... Read more

Pathology

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High-Risk HPV Evaluated for Invasive Cervical Cancer
Disease-Associated Variants in Genes Allow Early Diagnosis
Urine Biopsies Help Monitor Bladder Cancer Treatment
Image: Disseminated tumor cells (DTCs) stained by double immunofluorescence (AE1AE3/NR2F1 and AE1AE3/Ki67) and correlation between Ki67 and NR2F1 expression (Photo courtesy of the Icahn School of Medicine at Mount Sinai).

Dormant Disseminated Tumor Cells Stratified in Breast Cancer Patients

Breast cancer patients may experience relapse and subsequent death from the disease many years after primary treatment. This indicates an ability of occult cancer cells to survive in a non- or slow-proliferating... Read more

Lab Tech.

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Residual Tissue Repositories Suitable for MS-Based Proteomics
Magnetic Nanoparticle Tool Developed to Detect MicroRNA
Simple Paper Test Detects False or Substandard Antibiotics
Image: enVision: Test results are denoted by a color change and could be further analyzed by a smartphone app, making it attractive as a point-of-care diagnostic device (Photo courtesy of National University of Singapore).

Low-Cost Diagnostic Developed Using Nanostructures

The detection of pathogen nucleic acids has broad applications in infection diagnostics and management. Nucleic acid-based human papillomavirus (HPV) testing is essential to contemporary cervical cancer testing.... Read more

Industry News

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Increasing Conditions and Diseases Drive Global POC Hematology Diagnostics Marke...
Western Blotting Processors Market to Reach USD 329 Million by 2028
Global IVD Market to Reach USD 77 Billion by 2023
Image: The global hemostasis/coagulation analyzers market is expected to grow to USD 9.55 billion by 2026, driven mainly by the growing incidence of blood disorders (Photo courtesy of Analyticon Biotechnologies.

Global Hemostasis/Coagulation Analyzers Market to Reach USD 9.5 Billion by 2026

The global hemostasis/coagulation analyzers market was valued at USD 3.65 billion in 2017 and is expected to grow at a CAGR of 9.9% over the period 2018 to 2026 to reach USD 9.55 billion by 2026, driven... Read more

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