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Molecular Diagnostics

Image: The Luminex 200 multiplex analyzer (Photo courtesy of Luminex Corporation).

Cytokine Concentration Linked to Chronic Fatigue Syndrome

More than one million people in the USA suffer from chronic fatigue syndrome, also known as myalgic encephomyelitis and designated by the acronym ME/CFS. It is a disease with no known cure or even reliably effective treatments. More...
16 Aug 2017
Image: A histopathology of adrenal pheochromocytoma from an adrenectomy specimen showing the characteristic stippled (finely granular) chromatin (Photo courtesy of Nephron).

Mutations Related to Hereditary Neuroendocrine Tumors

Pheochromocytomas and paragangliomas are rare neuroendocrine tumors with a strong hereditary component and half the genes whose alterations confer hereditary susceptibility to develop this condition code for enzymes involved in the Krebs cycle. More...
16 Aug 2017
Image: The model illustrates clinical implications of BCBM CTC screening method for brain micro-metastasis before they become detectable by MRI. BCBM-associated CTCs can be used as a tool to evaluate responses to therapy for BCBM patients (Photo courtesy of Houston Methodist).

Blood Test Detects Brain Metastases While Treatable

A blood test is being generated that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time. More...
16 Aug 2017
Image: Brain scans from the study ‘Heterozygous de novo UBTF gain-of-function variant is associated with neurodegeneration in childhood’ (Photo courtesy of American Society of Human Genetics).

Neurological Disease Traced to Gene Error

A severe neurological rare disorder in children is characterized by developmental regression and neurodegeneration and at first the children lead normal lives and seem identical to their age-matched peers. More...
15 Aug 2017
Image: A prototype of the D4 assay (Photo courtesy of Daniel Joh, Duke University).

Smartphone-Based ELISA Developed for Blood Antigens

A novel high speed, lab-on-a-chip ELISA test for antigens in blood samples depends on a unique nonstick polymer coating that eliminates the need for multiple incubation and washing steps. More...
14 Aug 2017
Image: A technician collecting a fingerprick blood sample (Photo courtesy of iStock).

Dried Blood Assessment Equivalent to Drawn Blood Samples

A self-sampling method for therapeutic drug monitoring (TDM) of biologicals was developed that should enhance TDM implementation by patients with various autoimmune conditions. More...
14 Aug 2017
Image: The FilmArray respiratory panel enables rapid and accurate automated detection of pathogens causing respiratory infections (Photo courtesy of Idaho Technologies).

Test Discriminates Between Viral and Bacterial Infections

Lower respiratory tract infection (LRTI) commonly causes hospitalization in adults but because bacterial diagnostic tests are not accurate, antibiotics are frequently prescribed. Antibiotics are lifesaving drugs, but overuse is leading to antibiotic resistance, one of the world's most pressing health threats. More...
10 Aug 2017

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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