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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
05 Nov 2020 - 07 Nov 2020

Molecular Diagnostics

Image: Mutations in cell free DNA (cfDNA) or cells in the peripheral blood along with anemia or thrombocytopenia are the hallmark of myelodysplastic syndrome (MDS). The diagnosis of MDS is confirmed when mutations in hematopoietic cells are detected at relatively high levels (Photo courtesy of Genomic Testing Cooperative).

Inherited Causes of Clonal Hematopoiesis in Multiplicity of Whole Genomes

The age-related acquisition of somatic mutations that lead to clonal expansion in regenerating hematopoietic stem cell populations has recently been associated with both hematological cancer and coronary heart disease, and this phenomenon is termed clonal hematopoiesis of indeterminate potential (CHIP). More...
29 Oct 2020
Image: The signal of SMOLT is generated by the displacement of micron-size beads tethered by DNA long-probes that are between 1 and 7 microns long. The molecular extension of thousands of DNA probes is determined with sub-micron precision using a robust, rapid and low-cost optical approach (Photo courtesy of Scanogen).

Single-Molecule Tethering Detects Nucleic Acids and Microorganisms

Detection of microbial nucleic acids in body fluids has become the preferred method for rapid diagnosis of many infectious diseases. However, culture-based diagnostics that are time-consuming remain the gold standard approach in certain cases, such as sepsis. More...
29 Oct 2020
BIOHIT  Healthcare OY
Image: Scientists have greatly boosted the amount of information that can be obtained using Seq-Well S3, a technique for rapidly sequencing RNA from single cells (Photo courtesy of MIT).

Novel Method Reclaims Resolution of Single-Cell RNA-Seq

Single-cell RNA sequencing (scRNA-seq) is a powerful tool to characterize cells. Current scRNA-seq platforms, despite offering high throughput, are inefficient and provide low resolution among distinct cell states and molecular features. More...
28 Oct 2020
Image: A recently developed electrochemical bio‐barcode device paired with a smartphone enables cancer patients to read critical biomarker levels at home in samples of self-drawn blood (Photo courtesy of Georgia Kirkos, McMaster University)

An Electrochemical Bio-barcode Device for Home Disease Monitoring and Diagnosis

A point-of-care (POC) electrochemical bio‐barcode device and assay system have been developed to enable analysis of protein biomarkers in undiluted and unprocessed human plasma samples. More...
28 Oct 2020
Image: A sample collection kit for the expanded Multi-Cancer 83-gene comprehensive panel that increases diagnostic yield. Germline testing after tumor sequencing uncovers clinically actionable variants (Photo courtesy of Invitae).

Germline Testing After Tumor Sequencing Uncovers Clinically Actionable Variants

Genetic counseling and germline testing are recommended for patients with cancer who have suspected hereditary disease based on each patient’s presentation and family history. Separately, tumor DNA sequencing is increasingly used, most often in patients with advanced disease. More...
27 Oct 2020
Image: Digital droplet PCR (ddPCR): schematic showing oil droplets containing fluorescent PCR target molecules (Photo courtesy of Wikimedia Commons)

A Novel Liquid Biopsy Technique for Brain Tumor Diagnosis

A minimally invasive liquid biopsy technique enables diagnosis of glioma, the most common type of brain tumor, by PCR analysis of an easily obtained blood plasma sample. More...
27 Oct 2020
Image: Circulating tumor cells (CTCs) are cancer cells that are released and disseminated into the bloodstream and lymphatic system. CTC cultures were successfully propagated from breast epithelial cells (Photo courtesy of Menarini Silicon Biosystems).

Novel CTC Culture Method Developed to Study Metastatic Cancer

Cancer metastasis is responsible for most cancer-associated death. During metastasis, cells that escape the primary tumor into the circulatory system are known as circulating tumor cells (CTCs). More...
26 Oct 2020

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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