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Molecular Diagnostics

Image: Illustration of a 2019- novel coronavirus (nCoV) virion (Photo courtesy of Alissa Eckert, MS/CDC).

The Randox Laboratories Diagnostic Test Distinguishes Coronavirus from Other Respiratory Infections

 The global health diagnostics company Randox Laboratories (Crumlin, United Kingdom) has announced the release of a rapid diagnostic test for the COVID-19 strain of coronavirus. More...
21 Feb 2020
Image: The VisuLize Factor XI ELISA Kit is an Enzyme Immunoassay for the quantitative determination of Factor XI Antigen in human plasma samples using the double antibody enzyme linked immuno-sorbent assay (ELISA) (Photo courtesy of Affinity Biologicals, Inc).

Factor IX Inhibitor Incidence in Pediatric Hemophilia B Examined

 Hemophilia B is a blood clotting disorder causing easy bruising and bleeding due to an inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (hemophilia A). More...
20 Feb 2020
Image: Normal electrocardiogram (ECG) and an ECG showing QT interval prolongation (long QT syndrome). The P wave represents atrial depolarization; the QRS complex, ventricular depolarization; and the T wave, ventricular repolarization. The QT interval is measured from the beginning of the QRS complex to the return of the T wave to the isoelectric line (Photo courtesy of Mayo Clinic).

Several Genes Linked to Long QT Syndrome Reappraised

 Long QT syndrome (LQTS) is the first described and most common inherited arrhythmia. Over the last 25 years, multiple genes have been reported to cause this condition and are routinely tested in patients. More...
20 Feb 2020
Image: Copy number variants (CNVs) detection directly by UW-OncoPlex sequencing; depicted are examples from a melanoma and colon cancer sample (Photo courtesy of Noah G. Hoffman, MD, PhD).

Modular Targeted Capture Assay Detects Clinically Significant Oncology Alterations

 The rapid discovery of clinically significant genetic variants has translated to next-generation sequencing assays becoming out-of-date by the time they are designed, validated, and implemented. More...
19 Feb 2020
Image: Photomicrograph of a lymph node with almost complete replacement by metastatic melanoma (Photo courtesy of Wikimedia Commons)

Assessment of Circulating Tumor Cells Identifyies Stage III Melanoma Patients at Risk for Relapse

 Circulating tumor cells found in liquid biopsy specimens have been shown to be useful biomarkers for identifying stage III melanoma patients at risk for relapse. More...
19 Feb 2020
Image: Histopathology of Lung adenocarcinoma (Photo courtesy of Nikon).

Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans

 Lung adenocarcinoma is a subtype of non-small cell lung cancer (NSCLC). Lung adenocarcinoma is categorized as such by how the cancer cells look under a microscope. Lung adenocarcinoma starts in glandular cells, which secrete substances such as mucus, and tends to develop in smaller airways, such as alveoli. More...
18 Feb 2020
Image: The photo shows a portable lab that plugs into a smartphone to diagnose diseases like malaria or coronavirus (Photo courtesy of Joseph Fuqua II, University of Cincinnati Creative Services)

Autonomous Microchannel Analyzer Combines with Smartphone for Off-site Disease Diagnostics

 A novel microchannel capillary flow assay platform for detection of pathogenic microorganisms or other antigens combines with a smartphone for display, data transfer, storage, and analysis. More...
18 Feb 2020

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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.

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