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Molecular Diagnostics

Image: A malignant melanoma of the skin (Photo courtesy of Juan Gaertner).

Circulating Tumor DNA Detects Early Melanoma Growth

According to the National Cancer Institute, there were 91,270 new cases of melanoma in 2018, making up more than 5% of all new cancer cases. There were 9,320 estimated deaths in 2018, and 91.8% of patients survive five years or longer. More...
11 Dec 2018
Image: A diagram of the basis of the IvyGene Methylation-Based Liquid Biopsy Test to detect cancer (Photo courtesy of Dr. Kevin Conners).

Methylation-Based Liquid Biopsy Test Detects Liver Cancer

Hepatocellular carcinoma (HCC) represents about 75% of liver cancers in the USA and already has well-established screening criteria focused largely on individuals with cirrhosis, who are screened every six months using ultrasound with or without blood testing for alpha- fetoprotein, according to guidelines. More...
06 Dec 2018
Image: The CellSearch Platform for identification, isolation, and enumeration of circulating tumor cells (Photo courtesy of Menarini Silicon Biosystems).

Liquid Biopsy Detects Cancer across Multiple Biomarkers

Although biomarker-directed therapy is in its infancy in prostate cancer compared to some other tumor types, there is a great need for predictive biomarker testing, and great interest in noninvasive methods. However, comprehensive analysis of patients' cell-free DNA has been limited to date. More...
06 Dec 2018
Image: Gene recombination in neurons that produces thousands of new gene variants within Alzheimer’s disease brains have been identified (Photo courtesy of Sanford Burnham Prebys Medical Discovery Institute).

DNA Recombination in Brain Linked to Alzheimer's Disease

Alzheimer's disease is a public health crisis. The cause of the disease remains unknown and no meaningful treatment exists. Nearly six million people in the USA are living with Alzheimer's disease, a number projected to reach 14 million by 2060 as the population ages. More...
05 Dec 2018
Image: The NextSeq 550 System delivers the power of high-throughput sequencing with the speed, simplicity, and affordability of a benchtop next-generation sequencing (NGS) system (Photo courtesy of Illumina).

Genes Identified That Predispose People to Chronic Kidney Disease

Chronic kidney disease (CKD) affects 10% to 15% of the population worldwide and is now recognized as the most rapidly increasing contributor to global burden of disease. The costs related to CKD and end-stage renal disease (the terminal manifestation of CKD) are an enormous burden for all healthcare systems around the world. More...
05 Dec 2018
Image: The Kalazar Detect Rapid Test for Visceral Leishmaniasis (VL) is a rapid immunochromatographic strip assay for the qualitative detection of antibodies to L. donovani complex in human serum to aid in the presumptive diagnosis of VL (Photo courtesy of InBios).

LAMP Assay Validated for Visceral Leishmaniasis

Visceral leishmaniasis (VL) is one of the most neglected infectious diseases with an annual incidence of 50,000 to 90,000 new cases worldwide. Cases of VL are characterized by irregular bouts of fever, weight loss, hepatosplenomegaly, hypergammaglobulinemia, pancytopenia and anaemia. More...
03 Dec 2018
Image: An illustration showing detection of a single influenza virion using a solid-state nanopore (Photo courtesy of Osaka University).

Nanopore Method Detects Single Influenza Virus at Single Particle Level

A team of Japanese researchers has introduced a novel sensor concept capable of discriminating various types of influenza virus in a label-free fashion by their distinct particle properties. More...
03 Dec 2018

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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