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Molecular Diagnostics

The Quant-iT 1X dsDNA HS (High-Sensitivity) Assay Kit is designed to make DNA quantitation easy and accurate. The assay is highly selective for double-stranded DNA (dsDNA) over RNA (Photo courtesy of Thermo Fisher Scientific)

Automated Detection of Arm-Level Alterations for Individual Cancer Patients

Copy number alterations (CNAs) can be gains, losses, or loss of heterozygosity (LOH) of a chromosome segment. Based on the length of the altered segment, they are crudely classified as “focal alterations” and “arm-level alterations”. More...
25 Sep 2021
Structure of the TK1 protein (Photo courtesy of Wikimedia Commons)

Serum Levels of Thymidine Kinase Predict Disease Progression and Overall Survival of Metastatic Breast Cancer Patients

Blood serum levels of the enzyme thymidine kinase 1 (TK1) have been found to predict disease progression and overall survival of patients with metastatic hormone receptor-positive breast cancer (MBC). More...
25 Sep 2021

Certest Offers Real-Time PCR Assays for Fast Detection of MDR Bacterial Infections

CerTest Biotec (Zaragoza, Spain; www.certest.es) has joined the fight against multidrug resistant strains (MDR) bacterial infections by developing real-time PCR assays for the fast detection of genes or punctual mutations that confer resistance to antibiotics from both Gram-positive and Gram-negative pathogens. More...
23 Sep 2021

Thermo Fisher Launches World’s First Fully Integrated Digital PCR (dPCR) System

Thermo Fisher Scientific Inc. (Waltham, MA, USA) has launched the world’s first fully integrated digital PCR (dPCR) system designed to provide highly accurate and consistent results within 90 minutes. More...
22 Sep 2021
A heat-map, where red shows high levels of a compound, and blue shows low levels of a compounds, reveals the link between certain metabolites and dementia. Compounds in sub-group A were typically higher in dementia patients and lower in healthy elderly people. Compounds in sub-group B-E showed the opposite effect (Photo courtesy of Okinawa Institute of Science and Technology)

Metabolic Biomarker Panel Shows Promise for Diagnosis of Dementia

A biomarker panel based on five groups of metabolites was shown to be potentially useful for diagnosis and therapy of various forms of dementia, such as Alzheimer’s disease. More...
22 Sep 2021
Image: Acute lymphoblastic leukemia: bone marrow aspirate smear reveals increased blasts which are small to medium in size with high nuclear-to-cytoplasmic ratios, round to irregular nuclei, smooth chromatin, and scant basophilic agranular cytoplasm. Some background maturing myeloid cells are also present in this case (Photo courtesy of Karen M. Chisholm, MD, PhD)

Acute Lymphoblastic Leukemia Risk Linked to Genetically Mediated Increase in Lymphocytes

Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. As an acute leukemia, ALL progresses rapidly and is typically fatal within weeks or months if left untreated. More...
15 Sep 2021
Image: The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children (Photo courtesy of Cedars-Sinai Medical Center)

Biomarkers Found for COVID-19 MIS-C Condition in Children

Multisystem Inflammatory Syndrome in Children (MIS-C) manifests as a severe and uncontrolled inflammatory response with multiorgan involvement, occurring weeks after SARSCoV-2 infection. More...
13 Sep 2021

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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