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Molecular Diagnostics

Image: The LSM 700 laser scanning microscope (Photo courtesy of Zeiss).

Biomarker Identified for Aggressive Early Stage Cancer

Breast cancer begins as anomalous cells that divide out of control, usually in the milk ducts and in almost all cases, a patient does not succumb to the initial cancer but to the secondary tumors after the cancer has spread. More...
27 Apr 2017
Image: The Ziplex System, a medium-density microarray platform (Photo courtesy of Axela).

Blood Test Could Detect Abusive Head Trauma in Infants

A blood test has been developed and refined that could help clinicians identify infants who may have had bleeding of the brain as a result of abusive head trauma, sometimes referred to as shaken baby syndrome. More...
26 Apr 2017
Image: The fluorescent signal demonstrated by the Specific High Sensitivity Enzymatic Reporter UnLOCKing (SHERLOCK) system using CRISPR-Cas (Photo courtesy of the Broad Institute).

Sensitive NA Detection Aids Pathogen Diagnoses

Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring, and can be used to diagnose infections, such as Zika and dengue, with a high level of sensitivity. More...
26 Apr 2017
Image: A diagram of the method developed to detect and map DNA methylation, which can be a sign of cancer, by threading the DNA through a tiny hole in a thin sheet of conductive material with a current running through it (Photo courtesy of Aditya Sarathy, University of Illinois).

Detecting Cancer as DNA Changes Could Enhance Diagnosis

DNA methylation is an epigenetic modification involving the addition of a methyl group to DNA, which is heavily involved in gene expression and regulation, thereby critical to the progression of diseases such as cancer. More...
26 Apr 2017
Image: A photomicrograph of abnormal cervical cells staining positive for CINtec PLUS test (Photo courtesy of Ventana Medical Systems).

Cytology Test for Pre-Cancer Diagnosis Receives FDA Approval

A cytology test, which is the only clinically validated cyclin-dependent kinase inhibitor 2A (p16) biomarker test that, when used in conjunction with hematoxylin & eosin (H&E) staining, helps pathologists determine which women should receive treatment for cervical pre-cancer. More...
25 Apr 2017
Image: A Polymerase Chain Reaction (PCR) processing card for the BD Max molecular diagnostics platform (Photo courtesy of BD Diagnostic Systems).

Bacterial Panel Detects Stool Pathogens from Swabs

Repeated bouts of diarrhea and persistent diarrheal disease disrupt intestinal function and absorption, making diarrheal disease a leading cause of malnutrition in children less than 5 years of age. Importantly, diarrheal disease is both treatable when correctly diagnosed and preventable via proper infection control measures. More...
25 Apr 2017
Image: A comparison of analytical PCR procedures (Photo courtesy of Scientific Reports).

New sPCR Technology Runs on Standard Devices

Synergistic PCR (sPCR), a new method of DNA analysis developed for use on a new high-speed assay device, can also be carried out on widely available laboratory real-time PCR (qPCR) instruments and does not require calibration. More...
24 Apr 2017

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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