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Molecular Diagnostics

Image: A blood test for Vitamin D, where deficiency may indicate higher plasma lipid levels (Photo courtesy of bluehorizon).

High Vitamin D Levels Linked to Lower Cholesterol

Vitamin D is known to be essential for bone metabolism, and low serum 25(OH)D levels increase the risk of rickets, osteomalacia, and osteopenia. The associations of serum 25-hydroxyvitamin D (25(OH)D) with plasma lipids remain controversial in children. More...
19 Jun 2018
Image: An endometrial carcinoma showing loss of nuclear expression of MSH2. The lymphocytes and stromal cells should stain positive and represent an internal positive control (Photo courtesy of Memorial Sloan Kettering Cancer Center).

MSI Tumor Analysis Implicates Lynch Syndrome in Cancer Types

A new pan-cancer analysis suggests that there may be a benefit to doing germline testing for Lynch syndrome in advanced cancer patients who have high microsatellite instability (MSI) in their tumors. More...
19 Jun 2018
Image: The NextSeq 500 desktop sequencing platform (Photo courtesy of Illumina).

Molecular Test Developed for Nasopharyngeal Carcinoma

The prevalence of nasopharyngeal carcinoma (NPC) is higher in Southeast Asia than other parts of the world, around 35 cases per 100,000. Five-year survival rate of the disease is as high as 95% when it is detected early, but drops to 60% if detected at later stage. Most patients are asymptomatic, and so 80% are diagnosed with advanced disease. More...
12 Jun 2018
Image: The LightCycler 96 real-time PCR system (Photo courtesy of Roche Diagnostics).

RT-PCR Assay Developed to Detect Bloodstream Infections

Rapid detection and identification of a causative pathogen is essential in the treatment of critically ill patients with blood stream infection (BSI), since timely initiation of adequate antibiotic treatment is associated with decreased morbidity, mortality, and possibly reduced healthcare costs. More...
11 Jun 2018
Image: An intubated baby that was born prematurely 26 weeks, six days gestation, weighing 990 grams. Photograph was taken approximately 24 hours after birth (Photo courtesy of Wikimedia Commons).

Assay Detects CP Risk in Premature Babies

MicroRNA sequencing has been used for early diagnosis of premature babies with abnormal muscle tone and/or intraventricular hemorrhage (IVH) - symptoms that are considered to be indicators for risk of cerebral palsy. More...
11 Jun 2018
Image: The ABI 7300 real-time PCR system (Photo courtesy of Applied Biosystems).

Leprosy Neural Impairment Diagnosis Evaluated by Tests

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an obligate intracellular parasite with a predilection for infecting peripheral nerves and skin. Leprosy is a current and challenging disease, because it still represents a problem for public health in developing countries. More...
07 Jun 2018
Image: The TruSight Cardio Sequencing kit uses next-generation sequencing (NGS) to provide comprehensive coverage of 174 genes with known associations to 17 inherited cardiac conditions, including cardiomyopathies, arrhythmias, aortopathies, and more (Photo courtesy of Illumina).

Link Found Between Alcohol, Genes and Heart Failure

Alcoholic cardiomyopathy (ACM) is caused by chronic and excessive alcohol intake. Although moderate levels of alcohol consumption may have some beneficial cardiovascular effects, prolonged and excessive consumption can lead to deleterious consequences including cardiac arrhythmias and a dilated cardiomyopathy (DCM) phenotype. More...
07 Jun 2018

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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.

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