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Molecular Diagnostics

Image: A new study suggests that mutations in the gene CABLES1 may lead to Cushing syndrome (Photo courtesy of iStock).

Potential Genetic Cause of Cushing Syndrome Found

A recent study suggests that mutations in the gene Cdk5 And Abl Enzyme Substrate 1 (CABLES1) may lead to Cushing syndrome, a rare disorder in which the body overproduces the stress hormone cortisol. More...
22 Jun 2017
Image: Scientists used a blood test to measure NfL as a potential marker of neurodegeneration in patients with Huntington’s disease (Photo courtesy of Shutterstock).

Blood Test Predicts Onset of Huntington's Disease

Huntington's disease (HD) is a fatal genetic neurological disease. It usually develops in adulthood and causes abnormal involuntary movements, psychiatric symptoms and dementia and approximately 10,000 people in the UK have HD with around 25,000 at risk. More...
21 Jun 2017
Image: A histopathology of pancreatic adenocarcinoma, where the adenocarcinoma has wrapped around a nerve (center) (Photo courtesy of Johns Hopkins Medicine).

Pancreatic Cancer Potentially Diagnosed by ctDNA

Pancreatic cancer remains a devastating disease, with the diagnosis typically being made late. Circulating Tumor DNA (ctDNA) has shown promise as a screening test for various tumor types. More...
21 Jun 2017
Image: Dr. John Lewis, left, who developed the Extracellular Vesicle Fingerprint Predictive Score (EV-FPS) test, works with a graduate student (Photo courtesy of University of Alberta).

Blood Test Predicts Aggressive Prostate Cancer

Current tests such as the prostate specific antigen (PSA) and digital rectal exam (DRE) often lead to unneeded biopsies and more than 50% of men who undergo biopsy do not have prostate cancer, yet suffer the pain and side effects of the procedure such as infection or sepsis. More...
20 Jun 2017
Image: The UrNCollect device is designed for use with the SelectMDx in vitro diagnostic (IVD) PCR test kit for prostate cancer (Photo courtesy of MDxHealth).

New Diagnostic Products Detect Prostate Cancer

A novel sample collection device was designed to support a urine-based non-invasive "liquid biopsy" molecular diagnostic test that determines the risk for developing high-grade prostate cancer. More...
19 Jun 2017
Image: Scientists found that by testing for 19 new genetic factors in addition to the 25 risk genes already known, they could identify the 1% of men at highest risk of testicular cancer (Photo courtesy of Shutterstock).

Biomarkers Show Highest Risk for Testicular Cancer

Results of a large genome-wide association study (GWAS) have enabled the identification of 19 new risk loci and potential regulatory mechanisms influencing the susceptibility to testicular germ cell cancer. More...
19 Jun 2017
Image: The eazyplex MRSA test system is designed for the detection of S. aureus and MRSA (pictured) in invasive samples such as pleural and synovial fluid (Photo courtesy of MNT).

LAMP Assay Validated for MRSA in Invasive Samples

Staphylococcus aureus is a leading cause of bone and joint infections and one of the most common causative pathogens of bacterial pneumonia in children. An increased risk of mortality from invasive staphylococcal infections has been attributed to methicillin-resistant S. aureus (MRSA). More...
16 Jun 2017

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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.

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