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Image: Photomicrograph of a hematoxylin-eosin-stained human lung tissue specimen, harvested from a pulmonary aspergillosis patient. The histopathologic changes indicate the presence of Aspergillus sp. fungal organisms. Note the branching hyphae amongst the lung tissue (Photo courtesy of the Armed Forces Institute of Pathology).

Routine Blood Parameters Predict Invasive Aspergillosis Prognosis

Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems, e.g. those undergoing bone marrow transplantation. Symptoms include fever, chills, shock, delirium, seizures, and blood clots. More...
19 Nov 2019
Image: A blood film showing neutrophils and lymphocytes and other white and red blood cells, and a platelet (Photo courtesy of University of Minnesota).

Hematological Ratios Associated with Mortality in Pediatric Trauma Patients

Trauma-related injury as a potential cause of death affects millions of people worldwide, especially in less developed countries and furthermore, it is the leading cause of mortality in pediatric trauma patients. More...
14 Nov 2019
Image: The Abbott Architect i2000SR immunoassay analyzer (Photo courtesy of Abbott Diagnostics).

Reference Intervals Established for Serum Ferritin in Chinese Adults

As the foundation for the interpretation of medical laboratory data, reference intervals (RIs) for analytes are one of the most widely used clinical decision‐making tool. Nevertheless, although measurement of serum ferritin (SF) has largely replaced laboratory assays of serum iron and transferrin or total iron‐binding capacity in clinical practice, there is no gold‐standard method for measuring SF. More...
12 Nov 2019

Measurable Residual Disease Assessed Post-Transplantation in Acute Lymphoblastic Leukemia

The detection of residual disease by techniques more sensitive than light microscopy is called measurable residual disease (MRD) and is an important prognostic marker, which dictates outcome of disease. Assessment of measurable residual disease (MRD) is rapidly transforming the therapeutic and prognostic landscape of a wide range of hematological malignancies. More...
07 Nov 2019
Image: Blood drawn from a sickle cell patient (left) and from a patient after stem-cell transplant (right) (Photo courtesy of NIH Molecular and Clinical Hematology Branch).

Allogeneic Transplantation Outcomes Compared in Sickle Cell Disease Patients

Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape. More...
06 Nov 2019
Image: A histopathology of primary central nervous system lymphoma showing small purple cells along the blood vessel in the brain (Photo courtesy of Columbia University Medical Center).

Biomarkers Analyzed for Central Nervous System Lymphoma

Primary central nervous system lymphoma (PCNSL) is a rare type of extranodal non-Hodgkin lymphoma (NHL) accounting for 3% of all newly diagnosed primary intracranial tumors. In patients presenting with focal brain lesions, fast and reliable diagnosis of PCNSL remains a challenge. More...
29 Oct 2019
Image: Myeloperoxidase positive staining from a patient with acute myeloid leukemia (Photo courtesy of Monika Nema, MD).

Specific Cytokines Are Significant Biomarkers for AML

Acute myeloid leukemia is a hematopoietic neoplasm derived from early progenitor myeloid cells; it is characterized by clonal expansion of myeloblasts, which are immature myeloid progenitors that accumulate in the bone marrow (BM). More...
16 Oct 2019
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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