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Image: The ADVIA 2120 hematology analyzer (Photo courtesy of Siemens Healthcare).

Diagnostic Performance of Blood Counts Compared

The use of point-of-care testing is increasing, however many hematology analyzers can only determine granulocyte count without further differentiation into neutrophils, eosinophils and basophils. More...
17 Oct 2017
Image: The GEM 4000 whole blood analyzer (Photo courtesy of Werfen UK).

Umbilical Cord Bilirubin Predicts Neonatal Jaundice

Hyperbilirubinemia is one of the commonest causes of admission to hospital in the neonatal period amongst term babies in all settings. Prevention of serious complications depends on effective early treatment, but clinically significant jaundice may not develop until one or more days after delivery. More...
17 Oct 2017
ELITech Group
Image: Clinical uses of Warfarin, a drug that is used for the treatment of existing blood clots and to prevent new blood clots formation inside the body (Photo courtesy of Dr. Manish Goyal).

Genetic Testing Determines Safest Dose of Blood Thinner

Warfarin, commonly known as Coumadin, is frequently used to prevent a life-threatening blood clot. It is often prescribed to people having hip or knee replacement surgery, as well as to individuals with certain heart conditions that leave them vulnerable to a stroke. More...
12 Oct 2017
Image: The KX-21 N automated hematology analyzer (Photo courtesy of Sysmex Corporation).

Biomarkers of Sickle Cell and Hemoglobin SC Compared

Sickle cell disease (SCD) is a group of inherited diseases that includes sickle cell anemia (SCA), which is the homozygous state of the beta S (βS) allele and the most severe SCD genotype. The heterozygous state of the βS allele is characterized by the presence of hemoglobin S (HbS) and is associated with a group of less severe SCD, including hemoglobin SC disease (HbSC). More...
10 Oct 2017
Image: The qualitative point-of-care test CareStart G6PD RDT is a visual screening test that identifies G6PD deficient patients using whole blood sample. Panel A, no color change for sample with deficient G6PD enzymatic activity; Panel B, distinct purple color for sample with normal G6PD enzymatic activity (Photo courtesy of Access Bio).

Field Evaluation of Quantitative G6PD Diagnostics Reviewed

Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is the most common enzymopathy with at least 400 million individuals affected worldwide. More than 185 clinically relevant variants of G6PDd have been reported with a spectrum of associated enzyme deficiencies. More...
27 Sep 2017
Image: The novel automated slide-based approach: a microscope slide is moved under a blunt needle, providing a constant flow of whole blood. Typically, 1 μL of blood is deposited (Photo courtesy of James W. Winkelman, MD, et al).

Automated Slide-Based Approach Introduced for CBCs

The most commonly performed clinical laboratory test is the complete blood count (CBC). Currently, laboratory CBC systems obtain cell counts and morphologic information by maintaining the blood cells in a liquid “flow” and by using the Coulter impedance-based orifice or laser-based cytometry. More...
14 Sep 2017
Image: A photomicrograph of pleocytosis, which is an increased cell count, particularly an increase in white blood cell (WBC) count, in a bodily fluid such as cerebrospinal fluid (CSF) (Photo courtesy of Shutterstock).

CSF Pleocytosis Level Investigated as Diagnostic Predictor

Migration of leukocytes to the cerebrospinal fluid is a cardinal symptom of an infectious condition affecting the meninges or the cerebral parenchyma. Bacterial and viral meningitis cannot reliably be differentiated clinically and requires lumbar puncture to analyze the cerebrospinal fluid. More...
13 Sep 2017
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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