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Image: A bone marrow smear of a patient with Acute Myeloid Leukemia; dysplastic changes are noted in both the granulocytic and erythroid lineages (Photo courtesy of Peter Maslak).

Acute Myeloid Leukemia Regulatory Networks Identified

Adult acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes abnormal myeloblasts (a type of white blood cell), red blood cells, or platelets. AML is a heterogeneous disease caused by a variety of alterations in transcription factors, epigenetic regulators and signaling molecules. More...
28 Nov 2018
Image: The ABX Pentra 60 C+ automated hematological analyzer (Photo courtesy of Horiba).

Malaria Parasitaemia Correlated with Monocyte to Lymphocyte Ratio

In spite of a declining trend in the number of cases and deaths over the last few years, malaria still causes significant mortality and morbidity and the bulk of the burden is observed in children under five years of age. More...
28 Nov 2018
Image: A photomicrograph of sickle cells in human blood: both normal red blood cells and sickle-shaped cells are present (Photo courtesy of Dr. Graham Beards).

Rapid Test for Sickle-Cell Disease Evaluated

Sickle cell disease (SCD) is a common, life‐threatening genetic disorder that is best managed when diagnosed early by newborn screening. Sickle cell disease (SCD) is highly prevalent in sub-Saharan Africa and central India. Sickle cell anemia is the most common and severe form of SCD. More...
15 Nov 2018
Image: Bone marrow aspirate from a patient with multiple myeloma showing plasmacytosis (Photo courtesy of Feinberg School of Medicine).

RNA Defects Linked to Multiple Myeloma Progression

Multiple myeloma (MM) is the second most common type of blood cancer where cancer cells accumulate in the bone marrow, crowding out healthy blood cells. Studies on MM development have traditionally focused mostly on DNA abnormalities. More...
14 Nov 2018
Image: The ID Core XT blood group genotyping kit (Photo courtesy of Progenika Biopharma).

Blood Compatibility Assay Approved by FDA

Blood can be grouped based on the antigens on the surfaces of red blood cells, and the presence or absence of blood group antigens other than the ABO blood group antigens can be important in matching blood for transfusions. More...
12 Nov 2018
Image: The HiSeq 2500 System is a powerful high-throughput sequencing system (Photo courtesy of Illumina).

Functional Genomic Landscape of AML Analyzed

Acute myeloid leukemia is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells. More...
01 Nov 2018
Image: A blood smear from a 68-year-old woman with a 13-year history of polycythemia vera and there are three red blood cell precursors present and slight to moderate anisopoikilocytosis (Photo courtesy of The Armed Forces Institute of Pathology).

Myeloproliferative Neoplasms Fall into Genetic Subgroups

Myeloproliferative neoplasms are a group of chronic blood cancers associated with a risk of bleeding and blood clots, but they can also progress to more advanced disease, including leukemia. More...
31 Oct 2018

The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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