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Image: The ABI 7500 Real-Time PCR system (Photo courtesy of Applied Biosystems).

Molecular Diagnostics Prevents Malaria in Blood Banks

Haemovigilance is required to identify and prevent the occurrence or recurrence of unwanted transfusion-related transmissions and to increase the safety, efficacy and efficiency of blood transfusions. More...
18 Oct 2018
Image: Bone marrow aspirate of a patient with acute lymphoblastic leukemia revealing increased blasts which are small to medium in size with high nuclear-to-cytoplasmic ratios, round to irregular nuclei, smooth chromatin, and scant basophilic agranular cytoplasm. Some background maturing myeloid cells are also present in this case (Photo courtesy of Dr. Karen M. Chisholm).

Next-Gen Test Authorized for Minimal Residual Disease

An estimated 6,000 people in the USA will be diagnosed with acute lymphoblastic leukemia (ALL) and 31,000 people will be diagnosed with multiple myeloma this year. More...
17 Oct 2018
Image: The Autoscope uses deep-learning software to quantify the malaria parasites in a sample (Photo courtesy of Intellectual Ventures).

Automated Microscopy Compared for Routine Malaria Diagnosis

Microscopic examination of Giemsa-stained blood films remains a major form of diagnosis in malaria case management. However, as with other visualization-based diagnoses, accuracy depends on individual technician performance, making standardization difficult and reliability poor. More...
10 Oct 2018
Image: Bone marrow aspirate smear from a patient with myelodysplastic syndromes, unclassifiable (MDS-U) (pancytopenia and -7 cytogenetic abnormality). Occasional late mitotic figures in erythroid elements are present, but no significant erythroid or myeloid dysplasia exists (Photo courtesy of Dr. Robert P. Hasserjian, MD).

Disease Progression Apprised by Post-Treatment Mutation Sequencing

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for patients with myelodysplastic syndrome (MDS). The molecular predictors of disease progression after transplantation are unclear. More...
26 Sep 2018
Image: A blood film from a patient with acute myeloid leukemia (Photo courtesy of the University of Toronto).

DNA Test Predicts Risk of Leukemia Relapse

Acute myeloid leukemia (AML) is the most common type of leukemia in adults, comprising about one quarter of all cases. The disease stems from an overproduction of immature blood cells in the bone marrow, which over time outgrow normal blood cells. It's a type of cancer, which starts suddenly and progresses quickly, requiring urgent treatment. More...
25 Sep 2018
Image: The LSM 780 inverted laser scanning confocal microscope (Photo courtesy of Zeiss).

Biomarker Identified for Novel Asthma Treatment

Asthma is a widespread chronic airway disease characterized by airway obstruction, inflammation, and hyperresponsiveness. Symptoms such as bronchoconstriction and cough range from mild intermittent to severe persistent. More...
17 Sep 2018
Image: A blood film from a patient with Chronic Lymphocytic Leukemia (CLL); a large lymphocyte (arrow) has a notched nucleus and demonstrates the variable appearance of some of the lymphocytes in CLL (Photo courtesy of Peter Maslak).

New mRNA Cancer Drivers Revealed in Chronic Lymphocytic Leukemia

New evidence has emerged showing that the inactivation or alteration of cancer suppressor genes can take place even if DNA itself remains unaltered. A known molecular mechanism for cancer development and spread is the inactivation of tumor suppressor genes, which encode various tools the body uses to keep its cells from turning cancerous. More...
11 Sep 2018

The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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