Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Techlab

TECHLAB, Inc. develops, manufactures, and distributes rapid non-invasive intestinal diagnostics in the areas of intes... read more Featured Products: More products

Download Mobile App




Innovative C. Difficile Diagnostic Test Provides Both GDH and Toxin Results within 30 Minutes

By LabMedica International staff writers
Posted on 16 Jul 2024

Clostridium difficile is a leading cause of hospital-acquired diarrhea and pseudomembranous colitis. More...

Infections typically occur when antibiotics disrupt the normal gut flora. Toxigenic strains of C. difficile produce toxins A and B, which are responsible for the symptoms of the infection. Diagnosing C. difficile can be complex because it is possible to carry the bacteria without it producing disease-causing toxins. All strains of C. difficile produce glutamate dehydrogenase (GDH), making GDH testing a useful initial screen for the infection. However, additional tests are necessary since a GDH-positive result does not confirm if the strain is toxin-producing, which is necessary to determine if the patient has an active infection or is just a carrier. Now, a new test that provides results for both GDH and the toxins within approximately 30 minutes can help healthcare professionals accurately distinguish between active infection and colonization in a cost-effective and clinically relevant way.

The C. DIFF QUIK CHEK COMPLETE test from TECHLAB, Inc. (Blacksburg, VA, USA), a part of the SSI Diagnostica Group (Hillerød, Denmark), is a rapid membrane enzyme immunoassay that detects both the C. difficile GDH antigen and toxins A and B in a single reaction well. This test combines the screening and toxin detection steps of the traditional two-step algorithm into one, enhancing workflow efficiency, reducing turnaround time, and offering cost savings compared to the PCR-first algorithm.

The ability to make rapid clinical decisions is crucial for the effective treatment of patients with C. difficile infections, making it essential to obtain both screening and toxin results quickly. The C. DIFF QUIK CHEK COMPLETE test delivers both GDH and toxin results in about 30 minutes, effectively distinguishing between active infections and colonization with a single test that is both cost-effective and clinically relevant. Furthermore, the C. DIFF QUIK CHEK COMPLETE test is the first combined GDH and toxin A/B test to receive certification under the European In Vitro Diagnostic Medical Device Regulation (IVDR), affirming its compliance with stringent quality and safety standards. This certification ensures the test’s reliability and effectiveness for clinical use across Europe and represents a significant step forward in SSI Diagnostica’s efforts to improve diagnostic tools for C. difficile infections.

“We are proud to achieve IVDR certification for our C. DIFF QUIK CHEK COMPLETE test,” said Christina Lindved, CEO of SSI Diagnostica Group, “This achievement underscores SSI Diagnostica’s commitment to delivering high-quality diagnostic tools that meet the stringent regulatory requirements and fulfill the needs of healthcare providers and patients worldwide.”

Related Links:
TECHLAB, Inc. 
SSI Diagnostica Group


Gold Member
Flocked Fiber Swabs
Puritan® Patented HydraFlock®
3-Part Differential Hematology Analyzer
Swelab Alfa Plus Sampler
New
ESR Analyzer
TEST1 2.0
New
Human Estradiol Assay
Human Estradiol CLIA Kit
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Molecular Diagnostics

view channel
Image: The ONC IN-CYT platform leverages cross indication biomarker cyto-signatures (Photo courtesy of OraLiva)

AI-Powered Cytology Tool Detects Early Signs of Oral Cancer

Each year, 54,000 Americans are diagnosed with oral cancer, yet only 28% of cases are identified at an early stage, when the five-year survival rate exceeds 85%. Most diagnoses occur in later stages, when... Read more

Hematology

view channel
Image: The microfluidic device for passive separation of platelet-rich plasma from whole blood (Photo courtesy of University of the Basque Country)

Portable and Disposable Device Obtains Platelet-Rich Plasma Without Complex Equipment

Platelet-rich plasma (PRP) plays a crucial role in regenerative medicine due to its ability to accelerate healing and repair tissue. However, obtaining PRP traditionally requires expensive centrifugation... Read more

Immunology

view channel
Image: PD-1 protein blockade is the standard treatment for advanced melanoma among the different types of immunotherapy (Photo courtesy of 123RF)

Precision Tool Predicts Immunotherapy Treatment Failure in Melanoma Patients

Melanoma, though accounting for only about 4% of skin tumors, is the deadliest form of skin cancer due to its high potential to metastasize. While immunotherapy, especially PD-1 protein blockade, has revolutionized... Read more

Pathology

view channel
Image: Researchers have developed a novel method to analyze tumor growth rates (Photo courtesy of Adobe Stock)

Novel Method To Analyze Tumor Growth Rates Helps Tracks Progression Between Diagnosis and Surgery

Patients diagnosed with breast cancer often worry about how quickly their tumors grow while they wait for surgery, and whether delays in treatment might allow the disease to spread beyond the point of cure.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.