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Image: The OnSite Dengue Ag Rapid Test is a lateral flow chromatographic immunoassay for the qualitative detection of dengue NS1 antigen (DEN1, 2, 3, 4) in human serum, plasma or whole blood (Photo courtesy of CTK BioTech)

Novel Dengue Virus IgG Rapid Diagnostic Test Evaluated

Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. More...
16 Jun 2021
Image: Examples of negative and positive Chagas Stat-Pak RDT results. From left to right, negative, weakly positive, and strongly positive Stat-Pak results are shown (Photo courtesy of Yves Jackson)

Rapid Diagnostic Tests Evaluated for Chronic Chagas Disease Patients

Chagas is a disease caused by the parasite Trypanosoma cruzi, and is one of the most important public health concerns affecting the population of Latin America. This disease presents an acute phase that generally goes undiagnosed and a chronic phase with cardiac manifests principally, is diagnosed through serological tests that are generally not available. More...
15 Jun 2021
BIOHIT  Healthcare OY
Image: Quantikine ELISA kits are available in a range of formats for measuring intracellular and extracellular proteins (Photo courtesy of R&D Systems)

Serum Biomarkers Differentiates COVID-19 From Classic Cytokine Storm Syndromes

A cytokine storm, also called hypercytokinemia, is a physiological reaction in humans and other animals in which the innate immune system causes an uncontrolled and excessive release of pro-inflammatory signaling molecules called cytokines. More...
10 Jun 2021
Image: The Mindray BC-6800 hematology analyzer (Photo courtesy of Shenzhen Mindray Bio-Medical Electronics)

Platelet Indices Analyzed for Tuberculosis and Diabetes Mellitus Co-Morbidity

Studies have demonstrated that some diseases accelerate Tuberculosis (TB) occurrence and development. Type 2 diabetes mellitus (DM) has been verified as one of the threatening risk factors for TB, and patients have three times the risk of developing TB compared to non-diabetic patients due to pathogenic mechanisms and metabolic factors. More...
03 Jun 2021
Image: The CrAg LFA (lateral flow assay) can detect cryptococcal antigens in the blood of asymptomatic patients prior to development of cryptococcal meningitis enabling pre-emptive treatment of CrAg positive patients (Photo courtesy of Immy Diagnostics)

Cryptococcal Antigen Screening Evaluated Among People Living with HIV

 Cryptococcosis is a potentially fatal fungal disease caused by a few species of Cryptococcus (most often Cryptococcus neoformans or Cryptococcus gattii). Cryptococcosis is believed to be acquired by inhalation of the infectious propagule from the environment. More...
03 Jun 2021
Image: Computer-generated Mycobacterium tuberculosis bacteria, Ziehl-Neelsen stain. The reagents used are carbol fuchsin, acid alcohol, and methylene blue counterstain Acid-fast bacilli stain red and the background is blue (Photo courtesy of  microbiologyinpictures)

Serum Based Antigen Test Detects Childhood Tuberculosis

Approximately one million children develop tuberculosis (TB) and 205,000 die of TB-related causes each year. Eighty percent of these deaths occur in children < 5 years old, with the majority (96%) of deaths occurring among children who did not receive treatment, where missed diagnoses are likely responsible for undertreatment. More...
01 Jun 2021
Image: The Leptospira ELISA IgM assay (Photo courtesy of Panbio)

Leptospira IgM ELISA Evaluated Among Outpatients in Southern Asia

Leptospirosis is a widespread but neglected zoonotic disease caused by a bacterium of the genus Leptospira. Leptospirosis contributes to approximately 48,000 annual deaths globally, with 500,000 cases estimated worldwide, and remains a major public health concern in tropical and subtropical regions. Weil’s disease is a severe form of leptospirosis. More...
26 May 2021

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