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Microbiology

Image: Blue-stained dots are Chikungunya virus particles peppering the surface of an infected cell (Photo courtesy of Institute Pasteur/Thérèse Couderc).

RT-LAMP Used to Genotype and Diagnose Chikungunya

Chikungunya virus has re-emerged as an important pathogen causing several outbreaks in the world. As the clinical symptoms of chikungunya are similar to other mosquito-borne febrile diseases, the definitive diagnosis of the disease is based on the detection of viral genome from the patient blood. More...
27 Jun 2019
Image: A scanning electron photomicrograph of Candida albicans yeast cells (Photo courtesy of Science Photo Library).

Immune-Related Gene Implicated in Chronic Candida Infection Risk

Candida vaginitis is a frequent clinical diagnosis with up to 8% of women experiencing recurrent vulvovaginal candidiasis (RVVC) globally. RVVC is characterized by at least three episodes per year. More...
26 Jun 2019
Image: The HiSeq 2500 high-throughput sequencing system (Photo courtesy of Illumina).

Clinical Metagenomic Sequencing Improves Diagnosis of Neurological Infections

Metagenomic next-generation sequencing (NGS) is a promising approach for the diagnosis of infectious disease because a comprehensive spectrum of potential causes, viral, bacterial, fungal, and parasitic, can be identified by a single assay. More...
26 Jun 2019
Protocol summary of Vibrio cholerae DNA harvest from specimens preserved on filter paper cards (Photo courtesy of Wellcome Trust Sanger Institute).

Cholera Diagnosed from Dried Spotted Filter Paper

 Cholera outbreaks can rapidly induce high death tolls by overwhelming the capacity of health facilities, especially in remote areas or areas of civil unrest. Global estimates for cholera annually approximate four million cases worldwide with 95,000 deaths. More...
20 Jun 2019
The Prolisa C. difficile GDH EIA is a microwell assay for the qualitative detection of Clostridium difficile glutamate dehydrogenase (GDH) in fecal specimens. The test is intended for use as an aid in the diagnosis of C. difficile infections (Photo courtesy of Pro-Lab Diagnostics).

NA Amplification Tests for Clostridium Diagnosis Reviewed

 Clostridioides (Clostridium) difficile infection (CDI) is the leading cause of health care-associated infections in the USA. It accounts for 15% to 25% of health care-associated diarrhea cases in all health care settings, with 453,000 documented cases of CDI and 29,000 deaths in the USA in 2015. More...
19 Jun 2019
Chagas STAT-PAK assay is a rapid diagnostic test, easy to perform, requires no cold chain storage, uses a minimal sample size, and provides visual detection of antibodies to Trypanosoma cruzi (Photo courtesy of Chembio Diagnostic Systems).

Rapid Tests Assessed for Chronic Chagas Disease

 Chagas disease (CD) is a parasitic disease that can affect seriously the health status of affected individuals. People with CD, mainly living in remote areas of Latin America, often face major barriers to the disease recognition, diagnosis and treatment. In the U.S., there are estimated to be at least 300,000 cases of chronic Chagas disease among people originally from countries of Latin America where Chagas disease is endemic. More...
18 Jun 2019
Breast cancer cells invading through a layer of fibroblasts. Hormone receptor-positive breast cancer has been found to spread faster when the microbiome is disrupted (Photo courtesy of Institute of Cancer Research).

Unhealthy Gut Promotes Spread of Breast Cancer

 Most breast cancers, 65% or more, are hormone receptor positive. That means their growth is fueled by a hormone, either estrogen or progesterone. The good news is that these types of cancers are likely to respond well to hormone therapy. More...
18 Jun 2019


The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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