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Microbiology

Image: MinION sequencing device was used on three novel species for hybrid assembly (Photo courtesy of Oxford Nanopore Technologies)

Urinary Microbiome Linked to Prostate Cancer Risk

Prostate cancer is the most common non-skin malignancy in men in developed countries, with over 250,000 deaths annually worldwide. The clinical course of prostate cancer is highly heterogeneous, and critical decisions are made about the likelihood of aggressive disease based on information obtained at presentation. More...
02 May 2022
Image: The Bio-Rad QX200 Droplet Digital PCR (ddPCR) System provides absolute quantification of target DNA or RNA molecules for EvaGreen or probe-based digital PCR applications (Photo courtesy of Bio-Rad)

Duplex ddPCR Assay Evaluated for Salmonella and Shigella

Bacteria of the genus Salmonella and Shigella are important pathogens of infectious diarrhea. Salmonellosis was the second most commonly reported gastrointestinal infection in humans in the European Union in 2018. Shigella spp was the second leading cause of mortality caused by diarrhea among all ages in 2016 globally, accounting for 212,438 deaths. More...
28 Apr 2022
IIR Middle East
Image: Xpert MTB/RIF Ultra has the potential to reduce the number of missed smear-negative TB patients and may lead to a decrease in total costs of patient care due to the detection of MTB in patient specimens and RIF-resistance in a single test (Photo courtesy of Cepheid)

Xpert Ultra Nasopharyngeal Swab Assessed for Identification of Tuberculosis Deaths

Post-mortem studies have confirmed a high prevalence of tuberculosis (TB) at autopsy in sub-Saharan Africa (sSA), in up to 43% in HIV-positive adults, and more than 30% of adults dying at home with unknown cause of death. More...
21 Apr 2022
Image: Photo micrograph of Yersinia pestis bacteria stained with direct, fluorescent, antibody (Photo courtesy of Pixnio)

Lateral Flow Immunoassay Developed for Detecting Yersinia Pestis

Yersinia pestis is the causative agent of plague, a zoonosis associated with small mammals. Plague is a severe disease, especially in the pneumonic and septicemic forms, where fatality rates approach 100% if left untreated. More...
07 Apr 2022
Image: CloneJET PCR Cloning Kit is an advanced positive selection system for high-efficiency cloning of PCR products generated with any thermostable DNA polymerase (Photo courtesy of ThermoFisher Scientific)

Blood Test Identifies Stillbirth, Placentitis in Women with COVID-19

Recent reports have identified an increased risk of stillbirth in pregnant people infected with SARS-CoV-2. Perinatal pathologists have identified specific placental pathology, termed COVID placentitis, associated with a high risk of stillbirth and poor neonatal outcome. More...
06 Apr 2022
Image: The VITEK 2 system has everything healthcare laboratories need for fast, accurate microbial identification, and antibiotic susceptibility testing (Photo courtesy of bioMérieux)

Automated Systems Compared for Vancomycin MIC Values for MRSA Bacteremia

Staphylococcus aureus bacteremia is associated with significant morbidity and mortality. Compared with methicillin-susceptible isolates, methicillin-resistant Staphylococcus aureus (MRSA) increases hospital length of stay (LOS), hospital costs, duration of bacteremia, and mortality. More...
29 Mar 2022
Image: Photomicrograph of a blood sample specimen, revealed the presence of two flagellated, Trypanosoma cruzi parasites (Photo courtesy of Dr. Mae Melvin/CDC)

Double-antigen Sandwich ELISA Detects Antibodies to Trypanosoma cruzi

Chagas disease (CD), also known as American trypanosomiasis, is a potentially life-threatening vector-borne tropical zoonosis caused by the protozoan parasite Trypanosoma cruzi. The estimated prevalence of CD in 21 Latin American countries where it is considered endemic exceeds five million individuals; CD accounts for approximately 7,500 deaths annually. More...
29 Mar 2022


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