We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




Groundbreaking POCT Device Detects UTI Causing Bacteria in Five Minutes

By LabMedica International staff writers
Posted on 17 Aug 2023

Urinary tract infection (UTI) is a prevalent health concern globally, particularly affecting women during pregnancy. More...

Various bacteria can cause UTIs, leading to symptoms like a burning sensation during urination and an increased need to urinate. If the infection spreads to the kidneys, it can result in serious complications. Conventionally, urine cultures are used to detect and identify the specific bacteria responsible, a process that takes at least two days. This delay can cause suffering for the patient and even be fatal in some instances. In rural areas, the problem is exacerbated by inadequate infrastructure, high testing costs, and extended testing time, leading to many UTIs going undetected.

Researchers at the Indian Institute of Technology Guwahati (IIT Guwahati, Assam, India) have made a significant breakthrough by creating a 3D printed photodetector device that can identify and quantify a UTI-causing bacteria known as Klebsiella pneumoniae within five minutes from a urine sample. This capability is highly significant, as Klebsiella pneumoniae is not only a common cause of UTI but is also linked to pneumonia and soft tissue infections.

To create the prototype, the researchers utilized gold nanoparticles combined with specially engineered aptamers. An aptamer is similar to a 3D puzzle piece that fits only on the surface of specific bacteria. As a result, the gold nanoparticles get agglomerated on the surface of the target bacteria, generating a unique signature detectable by a UV-visible spectrophotometer. The device’s biosensor identifies changes in light intensity when the aptamer-gold nanoparticles-bacteria come together. The aptamer and bacteria combine instantly to result in rapid detection. Importantly, this innovative prototype is not only specific to Klebsiella pneumoniae but is also adaptable to different types of bacteria, offering great potential for primary healthcare. Furthermore, the cost-effective nature of the device could make it particularly beneficial in rural areas where UTIs frequently remain undiagnosed due to limited access to testing facilities.

Related Links:
IIT Guwahati 


New
Gold Member
Quality Control Material
iPLEX Pro Exome QC Panel
Serological Pipet Controller
PIPETBOY GENIUS
New
Drug Test Kit
DrugCheck 3000
New
PSA Assay
CanAg PSA EIA
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








DIASOURCE (A Biovendor Company)

Channels

Molecular Diagnostics

view channel
Image: The new RABTA sets a high standard in laboratory diagnostics (Photo courtesy of Randox)

Pioneering Analyzer with Advanced Biochip Technology Sets New Standard in Lab Diagnostics

A state-of-the-art analyzer combines advanced technology with exceptional efficiency to meet the demanding needs of modern laboratories. Randox Toxicology (Antrim, Ireland) has launched its pioneering... Read more

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: How the predictive test works (Photo courtesy of QMUL)

World’s First Clinical Test Predicts Best Rheumatoid Arthritis Treatment

Rheumatoid arthritis (RA) is a chronic condition affecting 1 in 100 people in the UK today, causing the immune system to attack its joints. Unlike osteoarthritis, which is caused by wear and tear, RA can... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.