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Immunology

Image: An MIT-invented microfluidics device could help doctors diagnose sepsis, a leading cause of death in US hospitals, by automatically detecting elevated levels of a sepsis biomarker in about 25 minutes, using less than a fingerprick of blood (Photo courtesy of Felice Frankel).

Microfluidic Device Rapidly Diagnoses Sepsis

Sepsis is a life-threatening condition and early diagnosis is crucial to ensure that treatment is not delayed. However, as current diagnostic methods are imprecise, the condition is misdiagnosed in 30% of patients. More...
15 Aug 2019
Image: The GeneXpert MTB/RIF assay is designed as a rapid diagnosis test of Tuberculosis (TB) and drug resistance (Photo courtesy of Cepheid).

Serum Siderocalin Measured in Patients with TB and HIV

Tuberculosis (TB) continues to be a significant cause of morbidity and mortality worldwide. The progression from uninfected or latently infected to active TB is often insidious and has minimal symptoms in the initial months, resulting in delayed diagnosis and poor outcomes. More...
14 Aug 2019
BIOHIT  Healthcare OY
Image: A colored scanning electron micrograph (SEM) of Enterococcus faecalis. These bacteria generate 12,13-diHOME and the concentration of the lipid itself in the babies’ stool samples predicted which infants went on to develop allergies (Photo courtesy of Pete Wardell/CDC).

Allergy Risk Increased by Compound Found in Infant Gut

Gut microbiota (formerly called gut flora) is the name given today to the microbe population living in our intestine. A recent study of newborn infants has identified a compound produced by gut bacteria that appears to predispose certain infants to allergies and asthma later in life. More...
14 Aug 2019
Image: The FACSymphony A5 system is a novel cell analyzer that leverages the inherent benefits of flow cytometry and enables the simultaneous measurement of up to 50 different characteristics of a single cell (Photo courtesy of BD Biosciences).

T Follicular Helper Cells Retain Lymphoid Characteristics

T follicular helper cells (Tfh) are a subset of CD4+ T cells that provide B cell help within the follicles of secondary lymphoid tissues. Tfh promote B cell class switching and affinity maturation, and without Tfh help, germinal centers (GC) fail to form. More...
13 Aug 2019
Image: A histopathology of chronic interstitial nephritis in end-stage kidney disease. There is diffuse interstitial scarring with a nonspecific mononuclear infiltrate (Photo courtesy of Agnes B. Fogo MD, Michael Kashgarian MD).

Abnormal Metabolite Observed in Early CKD Patients

Chronic kidney disease (CKD) has been a growing health burden worldwide, and the patients with CKD continue to suffer from a wide range of complication including electrolyte imbalance, fluid overload, bone and mineral metabolism disorder to anemia. More...
06 Aug 2019
Image: The Triple TOF 5600+ mass spectrometer (Photo courtesy of SCIEX).

Proteomics Approach Used for Analyses of Breast Cancer

Accurate classification of breast tumors is vital for patient management decisions and enables more precise cancer treatment. Despite the progress achieved in early cancer diagnosis and therapy, many patients develop the deadly disease. More...
31 Jul 2019
Image: The LSRFortessa flow cytometer instrument (Photo courtesy of BD Biosciences).

Rare Inherited Enzyme Disorder Yields Insight into Fibrosis

Mammalian tissues and organs preserve their structural and functional homeostasis by means of their supportive connective tissue, a three-dimensional network of cells and extracellular matrix (ECM) with different topological characteristics depending on the organ/tissue in which it is embedded. More...
31 Jul 2019


The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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