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Immunology

Image: A range of Elecsys and cobas Reagents for thyroid function test kits (Photo courtesy of Roche).

High Thyroid Hormone Levels Associated with Arterial Disease

Atherosclerosis is the process of progressive thickening and hardening of the walls of arteries from fat deposits on their inner lining. Atherosclerosis progresses insidiously from a subclinical condition to the clinical onset of vascular events to death. More...
15 Nov 2017
Image: A photomicrograph of a renal biopsy specimen suggesting acute tubular necrosis is the patchy or diffuse denudation of the renal tubular cells with loss of brush border (blue arrow) (Photo courtesy of the University of Alberta).

Autoimmune Disease Discovered Causes Kidney Failure

An insidious new autoimmune disease that causes kidney failure has been discovered. The condition causes a build-up of waste products in the blood and makes it difficult for kidneys to maintain adequate balance of fluid in the body. More...
15 Nov 2017
ELITech Group
Image: An immunohistochemistry of PharmDX 22c3 staining of non-small-cell lung carcinoma (Photo courtesy of Agilent).

Assay Identifies Patients Benefiting from Cancer Immunotherapies

Programmed cell death ligand 1 (PD-L1) has been detected in up to 50% of all human cancers, and has become a major focus of therapeutic and biomarker studies. More...
14 Nov 2017
Image: An immunohistochemistry of the new biomarker DNAJB9 greatly improves diagnostic sensitivity for the rare kidney disease, fibrillary glomerulonephritis (Photo courtesy of Mayo Clinic).

Potential Autoantigen Identified in Aggressive Kidney Disease

Fibrillary glomerulonephritis (FGN) is an aggressive kidney disease, and nearly half of patients become dependent on dialysis within several years of diagnosis. No unique clinical markers of FGN have been identified to help diagnose FGN, and current tests involve time-consuming analyses with light microscopy, immunofluorescence, and electron microscopy. More...
13 Nov 2017
Image: Immunostaining for immunoglobulin G4 (IgG4) in IgG4-related inflammatory aortic aneurysm; abundant IgG4-positive plasma cell infiltration (Photo courtesy of Shiga University of Medical Science).

Disease Associations Discovered with Four IgG Subclasses

Immunoglobulin G4-related disease (IgG4-RD) is a relatively newly defined disease entity that refers to a group of immune-mediated disorders that have certain histopathologic, serologic, and clinical features in common. More...
08 Nov 2017
Image: The Videssa Breast is the first blood test of its kind that detects and analyzes multiple types of tumor protein biomarkers for improved cancer detection (Photo courtesy of Provista Diagnostics).

Blood Test Can Effectively Rule Out Breast Cancer

Breast density is associated with reduced imaging resolution in the detection of breast cancer. Breast density is a radiologic phenomenon that is not discernable by palpation; it is a radiologist’s assessment. Imaging rays permeate dense breast tissue in a more opaque manner, thereby reducing image resolution. More...
07 Nov 2017
Image: The ADXBLADDER MCM5 ELISA kit for the diagnosis of bladder cancer (Photo courtesy of Arquer Diagnostics).

Noninvasive Test Detects Bladder Cancer

In Europe, bladder cancer represents the fourth most common cancer in men and the 15th most common cancer in women, with 151,000 people diagnosed with the condition in 2012. In order to make a bladder cancer diagnosis, experts currently recommend cystoscopy for all patients with hematuria, in conjunction with computed tomography (CT) urography (in selected high-risk patients) or renal and bladder ultrasound. More...
07 Nov 2017


The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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