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Image: Diminishing myelin sheaths: The damaged areas (at the bottom of the image) of the brains of MS patients lack myelin (at the top, in blue) (Photo courtesy of Dr. med. Imke Metz, University of Göttingen).

Link Between Gut Flora and MS Discovered

Multiple sclerosis (MS) is an immune-mediated autoimmune disease of the central nervous system that develops in genetically susceptible individuals and likely requires environmental triggers. In MS the body's own immune system attacks and damages the protective coating around nerve cells. More...
22 Oct 2018
Image: The MiSeq Sequencing platform (Photo courtesy of Illumina).

Human Pegivirus Identified in Encephalitis Patients

Human pegivirus (HPgV), was previously called hepatitis G virus or GB virus C, and is a lymphotropic virus with undefined pathology and many viruses from the family Flaviviridae, to which HPgV belongs, are neurotropic. More...
17 Oct 2018
Image: Higher levels of the inflammatory biomarker soluble tumor necrosis factor receptor-1 (sTNFR-1) are tied to kidney decline in healthy adults (Photo courtesy of Enbrel).

Kidney Function Decline Linked with Inflammatory Marker Levels

Tumor necrosis factor receptor-1 (TNFR-1), which plays a causative role in endothelial cell dysfunction and inflammation, is expressed on the cell surface in glomerular and peritubular capillary endothelium of the kidneys. More...
15 Oct 2018
Image: A diagram of urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment (Photo courtesy of University College London).

Urine Biopsies Help Monitor Bladder Cancer Treatment

Despite the advances in cancer immunotherapy, only a fraction of patients with bladder cancer exhibit responses to checkpoint blockade, highlighting a need to better understand drug resistance and identify rational immunotherapy combinations. More...
10 Oct 2018
Image: CT45, a biomarker marker found in some ovarian cancer cells, is associated with extended disease-free survival for women with advanced ovarian cancer (Photo courtesy of University of Chicago Medical Center).

Ovarian Cancer Biomarker Predicts Therapy Response

Despite months of aggressive treatment involving surgery and chemotherapy, about 85% of women with high-grade widespread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but never to a cure. About 15% of patients, however, do not have a recurrence and most of those women remain disease free for years. More...
01 Oct 2018
Image: An ELISA Kit for Kidney Injury Molecule 1 (Kim1) (Photo courtesy of Enzo Life Sciences).

Blood Test May Help Detect Kidney Cancer Earlier

Renal cell carcinoma (RCC) has the potential for cure with surgery when diagnosed at an early stage. Kidney injury molecule-1 (KIM-1) has been shown to be elevated in the plasma of RCC patients. More...
26 Sep 2018
Image: The Immage 800 immunochemistry system (Photo courtesy of Beckman Coulter).

Biomarkers Correlated with Idiopathic Inflammatory Myopathy

Patients with idiopathic inflammatory myositis (IIM) typically present with muscle weakness, myalgia and in case of dermatomyositis (DM) also skin involvement. Arthralgia is often present, but the articular manifestations are usually mild and non-destructive. More...
25 Sep 2018

The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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