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Immunology

Image: Strongyloides stercoralis adult. The parasitic female lives threaded into the mucosal epithelium of the human small intestine (Photo courtesy of UVM Ecological Parasitology).

Systematic Serological Screening Programme Used for Strongyloidiasis

 Strongyloidiasis is a soil-transmitted helminth infection caused by the nematode Strongyloides stercoralis and is endemic mainly in tropical and subtropical regions, but also in temperate regions. More...
13 Nov 2019
Image: The Abbott Architect i2000SR immunoassay analyzer (Photo courtesy of Abbott Diagnostics).

Reference Intervals Established For Serum Ferritin In Chinese Adults

As the foundation for the interpretation of medical laboratory data, reference intervals (RIs) for analytes are one of the most widely used clinical decision‐making tool. Nevertheless, although measurement of serum ferritin (SF) has largely replaced laboratory assays of serum iron and transferrin or total iron‐binding capacity in clinical practice, there is no gold‐standard method for measuring SF. More...
12 Nov 2019
Image: Preeclampsia is a pregnancy complication marked primarily by high blood pressure and organ damage. The diagnostic values of STAT4 and sEng in preeclampsia have been analyzed (Photo courtesy of Johns Hopkins University).

Diagnostic Values of Serum STAT4 and sEng Analyzed in Preeclampsia

Preeclampsia is a pregnancy complication characterized by high blood pressure and signs of damage to another organ system, most often the liver and kidneys. Preeclampsia usually begins after 20 weeks of pregnancy in women whose blood pressure had been normal. More...
06 Nov 2019
Image: The MenoCheck picoAMH ELISA is FDA cleared for in vitro diagnostic use as an aid in the determination of menopausal status in women between 42 and 62 years of age (Photo courtesy of Ansh Laboratories).

Anti-Müllerian Hormone Immunoassay Validated

Anti-Müllerian hormone (AMH) is a homodimeric glycoprotein with roles in regulation of fetal sexual differentiation and folliculogenesis in the adult ovary. AMH is increasingly used as a biomarker of ovarian reserve in clinical practice, and is used both for management of fertility treatments and prediction of menopause. More...
04 Nov 2019
Image: The DuoSet ELISA kit for determining levels of MMP-3 and TIMP-1 (Photo courtesy of R&D Systems).

Vaginal Biomarkers Predict Preterm Birth Risks

Premature birth and its complications are the largest contributors to infant death in the USA and globally. Complications of preterm birth are the single largest cause of neonatal deaths and account for 35% of the world’s 3.1 million neonatal deaths each year. More...
04 Nov 2019
Image: The Holomics Reader HRDR-300 mobile device was used to measure fluorescent intensity of the quantum dots complex after lateral migration of patient serum (Photo courtesy of Medical College of Georgia).

POC Test Based on Quantum Dots Detects Antibody Responses

Point-of-care (POC) assays, which can be performed at or near the site of care with a rapid turnaround time, are pivotal to transforming global disease control efforts, particularly in resource-constrained settings where access to laboratory facilities is limited. More...
31 Oct 2019
Image: The Synergy HTX multi-mode microplate reader is a compact, affordable system for 6- to 384-well microplates and Take3 Micro-Volume Plates (Photo courtesy of BioTek).

Fluorimetric Assay Quantifies Galactocerebrosidase Activity in Dried Blood Spots

The lysosomal enzyme galactocerebrosidase hydrolyzes glycosidic bonds of several glycosphingolipids, including galactose from galactosylsphingosine (psychosine), and is essential to prevent the toxic accumulation of psychosine in the body. More...
29 Oct 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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