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Immunology

Image: The UNI-CAP immunoanalyzer is intended for allergy testing using ImmunoCAP (Photo courtesy of Thermo Fisher Scientific)

Immunobiomarkers in Chronic Rhinosinusitis Correlate with Clinical Severity

Chronic rhinosinusitis comprises a heterogeneous group of inflammatory disorders. It is assumed that the disease process lasts over 12 weeks and is accompanied by two or more symptoms, such as nasal discharge/postnatal drip, nasal congestion, sinus pain/pressure, and anosmia/hyposmia. More...
06 Jul 2022
Image: The Bio-Rad iMark Microplate Absorbance Reader (Photo courtesy of Electronics Depot USA)

Maternal Autoantibody Profiles Are Biomarkers for Autism

Autism is a neurodevelopment condition affecting 1 in 44 children in the U.S. It has a wide range of characteristics with different intensities and causes. One type of autism is maternal autoantibody–related autism spectrum disorder (MAR ASD). More...
28 Jun 2022
Image: Neuronal marker positivity in the middle frontal and inferior temporal gyrus of human post-mortem brains with common tauopathies (Photo courtesy of University of California San Francisco)

Caspase-6-Cleaved Tau Is Relevant in Alzheimer's Disease

Alzheimer’s disease (AD) is characterized by the formation of aggregates of the tau protein in brain cells called neurofibrillary tangles. Although deposits of the amyloid β-protein are also found in AD brains, some scientists think that the tau protein aggregates are primarily responsible for the development of AD. More...
27 Jun 2022
Image: Histological features of collagenous colitis (Photo courtesy of Michael Bonert, MD, FRCPC)

Lack of Autoantibodies Against Related Proteins in Collagenous Colitis

Collagenous colitis (CC) is an inflammatory disorder in the colonic mucosa that predominantly affects elderly women and causes chronic, non-bloody diarrhea with normal or close to normal endoscopic findings. More...
21 Jun 2022
Image: The gold standard for the determination of antinuclear antibodies (ANA) is the indirect immunofluorescence test (IIFT) with human epithelial cells (HEp-2), which is known for its high sensitivity and specificity (Photo courtesy of Euroimmun)

Serological Markers of RA Determined in Patients with aβ2GPI-IgA

Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease. It is characterized by synovial inflammation that can lead to irreversible joint damage and disability when not managed. Biomarkers of RA available for routine clinical use are rheumatoid factors (RF) and anti-cyclic citrullinated peptides (CCP-Ab). More...
14 Jun 2022
Image: The Human P-Selectin ELISA Kit – serum vimentin levels were positively correlated with P-selectin in pediatric severe sepsis (Photo courtesy of MULTI SCIENCES(LIANKE) BIOTECH, CO.,LTD).

Serum Vimentin Predicts Mortality in Pediatric Severe Sepsis

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is a leading cause of death worldwide in the pediatric population. Vascular hyperpermeability by loss of endothelial barrier integrity is a hallmark of sepsis. More...
14 Jun 2022
Image: With the autoMACS Pro Separator, cells from whole blood or bone marrow can be isolated with minimal hands-on time (Photo courtesy of Miltenyi Biotec)

MRD in AML Detected by Deep Sequencing CD34+ Cells

Monitoring of measurable residual disease (MRD) in patients with acute myeloid leukemia (AML) is predictive of disease recurrence and may identify patients who benefit from treatment intensification. More...
09 Jun 2022


The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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