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Immunology

The enzyme-linked immunosorbent assay for estradiol (E2) (Photo courtesy of Calbiotech).

Higher Estrogen Levels Linked to Severe Disease in Scleroderma

 Systemic sclerosis (SSc) is an autoimmune, connective tissue disease of unknown etiology characterized by immune system dysregulation and excessive extracellular matrix (ECM) synthesis. As in most autoimmune diseases, there is a female predominance in SSc with a female to male ratio of 3:1, which increases to 9:1 during childbearing years. More...
19 Jun 2019
The Prolisa C. difficile GDH EIA is a microwell assay for the qualitative detection of Clostridium difficile glutamate dehydrogenase (GDH) in fecal specimens. The test is intended for use as an aid in the diagnosis of C. difficile infections (Photo courtesy of Pro-Lab Diagnostics).

NA Amplification Tests for Clostridium Diagnosis Reviewed

 Clostridioides (Clostridium) difficile infection (CDI) is the leading cause of health care-associated infections in the USA. It accounts for 15% to 25% of health care-associated diarrhea cases in all health care settings, with 453,000 documented cases of CDI and 29,000 deaths in the USA in 2015. More...
19 Jun 2019
Image: The NimbleGen MS 200 CGH LOH microarray detection scanner (Photo courtesy of Roche).

Kidney Transplant Rejection Linked to New Mismatch Locus

Approximately 20% of the kidney waiting list in the USA consists of candidates whose allografts have failed. Acute rejection is one of the strongest predictors of decreased allograft survival. More...
13 Jun 2019
Image: The LSRFortessa cell analyzer offers the ultimate in choice for flow cytometry, providing power, performance, and consistency (Photo courtesy of BD Biosciences).

Flow Cytometry Standardized for Predicting Transplant Rejection

Understanding the immunological phenotype of transplant recipients on standard immunosuppression, immune-cell therapies and new drug treatments is essential for improving transplantation outcome. More...
12 Jun 2019
Image: The PLATELIA ASPERGILLUS Ag Test (Photo courtesy of Bio-Rad Laboratories).

Invasive Pulmonary Aspergillosis Diagnosed by Molecular Test

Invasive aspergillosis (IA) is a common opportunistic fungal infection, mainly affecting patients with severe and prolonged neutropenia. Early diagnosis of invasive pulmonary aspergillosis (IPA) is notoriously difficult, but crucial for prompt treatment initiation required to improve patient outcome. More...
12 Jun 2019
Image: A typical human serum mannose-binding lectin enzyme-linked immunoassay kit (Photo courtesy of Hycult Biotech).

Mannose-Binding Lectin Associated with IgG Subclass Deficiency

Mannose-binding lectin (MBL; mannan-binding protein or lectin) is involved in innate immune defense, is produced largely by hepatocytes and is encoded by MBL2 (chromosome 10q21.1). MBL promotes killing of microorganisms by complement activation via the lectin pathway and by opsonization. More...
11 Jun 2019
Image: The unique pipette tip created with a 3D printer to perform enzyme-linked immunosorbent assays (Photo courtesy of the University of Connecticut).

Novel 3D-Printed Technology Lowers Cost of ELISA

Traditional enzyme-linked immunosorbent assay (ELISA) tests are performed on plates featuring 96 micro-wells; each well works as a separate testing chamber where samples can be combined with various agents that will then react with the sample, typically by changing color. More...
06 Jun 2019


The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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