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Image: ROC curve AUC and levels of Proenkephalin A 119–159 (PENK) 48 hours after liver transplantation in the need-renal replacement therapy groups (Photo courtesy of University of Sao Paulo)

Biomarker Proenkephalin Investigated in Diagnosis of Acute Kidney Injury

Liver transplantation (LT) is the only treatment available for patients with end-stage liver disease, such as liver cancer or acute and subacute liver failure. Among the various types of postoperative organ damage, acute kidney injury (AKI) is particularly prevalent, developing in 5% to 20% of patients undergoing major non-cardiac surgery. More...
12 May 2022
Image: The Vectra 3 System for Quantitative Pathology Imaging (Photo courtesy of PerkinElmer)

Immunohistochemistry Biomarkers Used to Subtype Gastric Intestinal Metaplasia

Gastric cancer (GC) is the fifth most common and third most lethal cancer globally. Patients with GC are often asymptomatic, with presentation occurring at advanced stage, and a low 5-year survival rate in most countries. Intestinal metaplasia is considered a key pivot point in the Correa model of GC. More...
04 May 2022
IIR Middle East
Image: Histopathology showing a pulmonary arteriole from a patient with systemic sclerosis-associated pulmonary artery hypertension showing significant medial hypertrophy (Photo courtesy of University of Colorado)

Antibody Test Identifies Scleroderma Patients at High Risk for Pulmonary Hypertension

Scleroderma is caused by the immune system attacking the connective tissue under the skin and around internal organs and blood vessels. This causes scarring and thickening of the tissue in these areas. More...
02 May 2022
Image: The Ella Automated Immunoassay System (Photo courtesy of R&D Systems)

Cytokine Signature Identifies COVID-19 Patients With Worst Prognosis

An overreaction of the immune system, in which excessive levels of proteins called cytokines produce damaging levels of inflammation, can lead to organ failure and death in COVID-19 patients. More...
27 Apr 2022
Image: BOND-MAX Fully Automated IHC and ISH Staining System (Photo courtesy of LeicaBiosystems)

Single-Cell Proteomics of Localized Prostate Cancer Defines Disease Heterogeneity

Prostate cancer affects about 12.6% of men over the course of their lives, and while most individuals with localized disease can be cured, disease does recur in a small number of patients. The treatment of localized prostate cancer is based on clinicopathological information including Gleason score, prostate-specific antigen (PSA) levels, stage, and patient age. More...
26 Apr 2022
Image: BD Rhapsody TCR/BCR multiomic assay advances immunology research capabilities in multiomics (Photo courtesy of BD)

New BD Assay Speeds Discovery in Autoimmune Disorders, Immuno-Oncology, and Infectious Diseases

Becton, Dickinson and Company (BD Franklin Lakes, NJ, USA) has launched the BD Rhapsody TCR/BCR Multiomic Assay, an innovative set of reagents that enables researchers to more easily and comprehensively analyze important cells in the immune system, providing a tool to advance research in autoimmune disorders, immuno-oncology and infectious diseases. More...
22 Apr 2022
Image: The LUNA-FL Dual Fluorescence Cell Counter (Photo courtesy of Logos Biosystems)

Tumor Suppressor Adenomatous Polyposis Coli Regulates T Lymphocyte Migration

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease that often results from germline mutations in the adenomatous polyposis coli (APC) gene, a tumor suppressor and polarity regulator. APC protein regulates the Wnt/β-catenin signaling pathway as a component of the β-catenin destruction complex. More...
20 Apr 2022

The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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