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Image: A scanning electron microscope (SEM) photograph of Papillomavirus particles (Photo courtesy of the Institut Pasteur/Odile Croissant).

RNA-Based Test Developed for HPV Detection and Cancer Diagnosis

An RNA-based diagnostic test was developed that can detect human papillomaviruses (HPVs) with performances comparable to or better than an HPV DNA-based reference diagnostic kit. More...
19 Aug 2019
Image: Circulating tumor DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized (Photo courtesy of Wikimedia Commons).

Ultrasensitive Biopsy Technique Monitors Risk of Cancer Recurrence

An ultrasensitive liquid biopsy technique, which may be personalized for each breast cancer patient, can be used to monitor the patient over time and allow early detection of tumor recurrence. More...
19 Aug 2019
BIOHIT  Healthcare OY
Image: The presence of lymphocytes within the tubular epithelium, attesting to acute cellular rejection of a renal graft (Photo courtesy of Wikimedia Commons).

Gene Panel Detects Early Signs of Kidney Transplant Rejection

A team of European kidney transplantation researchers has developed and validated an mRNA-based gene set found in peripheral blood that can identify patients with symptoms of antibody-based kidney transplant rejection. More...
12 Aug 2019
Image: A micrograph of non-alcoholic fatty liver disease (NAFLD). The liver has a prominent (centrilobular) macrovesicular steatosis (white/clear round/oval spaces) and mild fibrosis (green). The hepatocytes stain red. Macrovesicular steatosis is lipid accumulation that is so large it distorts the cell\'s nucleus (Photo courtesy of Wikimedia Commons).

Single Mutation Linked to Fatty Disorders of Liver and Skin

The common liver disorder non-alcoholic fatty liver disease (NAFLD) has been found to share a genetic linkage with Chanarin-Dorfman syndrome, a rare skin condition. More...
05 Aug 2019
Image: In brains affected by Alzheimer’s disease, abnormal levels of the beta-amyloid protein clump together to form plaques (seen in brown) that collect between neurons and disrupt cell function. Abnormal collections of the tau protein accumulate and form tangles (seen in blue) within neurons, harming synaptic communication between nerve cells (Photo courtesy of the [U.S.] National Institute on Aging).

Using Transcriptome Analysis to Detect Asymptomatic Alzheimer’s Disease

Transcriptome analysis was used as a method for detecting individuals with Alzheimer’s disease (AD) who were not yet displaying symptoms of the disorder. More...
29 Jul 2019
Image: Silencing of the FMR1 gene in Fragile X syndrome. FMR1 co-localizes with a rare fragile site, visible here as a gap on the long arms of the X chromosome (Photo courtesy of Wikimedia Commons).

Rare Neurodegenerative Disorders Share DNA Repeat Mutation

Genomics researchers have found that at least four rare neurodegenerative diseases result from CGG (cytosine-guanine-guanine) repeat mutations the DNA located in distant, seemingly unrelated areas of the genome. More...
29 Jul 2019
Image: A new study identified eight genetic variants linked to anorexia nervosa, and suggests that the genetic origins of the disorder are both metabolic and psychiatric (Photo courtesy of Medical Xpress).

Genetic Loci Significantly Associated with Anorexia Nervosa

Data accumulated by a large-scale genome-wide association study suggested that anorexia nervosa should be redefined as a “metabo-psychiatric disorder”, since at least eight genetic loci were identified as being significantly associated with the syndrome. More...
22 Jul 2019

BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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