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BioResearch

Image: A micrograph of Neisseria meningitidis in cerebrospinal fluid (CSF) seen by Gram stain at 1000x magnification. Infection could be prevented by vaccination (Photo courtesy of Wikimedia Commons).

Study Explains Link between Genetic Variation and Vaccine Specificity and Persistence

To better explain how genetic variation affects antibody production and specificity following immunization, researchers conducted a GWAS (genome-wide association study) to examine the persistence of immunity following administration of three childhood vaccines. More...
24 Jun 2019
Image: An illustration depicting areas affected by diabetic peripheral neuropathy (DNP) (Photo courtesy of Wikimedia Commons).

Genetic Locus Linked to Diabetic Peripheral Neuropathy in Type II Diabetes

Results of a genome-wide association study (GWAS) have identified a genetic locus linked to the development of diabetic peripheral neuropathy (DPN) by individuals suffering from type II diabetes. More...
24 Jun 2019
Image: A micrograph of a coronary artery with the most common form of coronary artery disease (atherosclerosis) and marked luminal narrowing (Photo courtesy of Wikimedia Commons).

Polygenic Risk Scores Accurately Predict Risk of Coronary Artery Disease

Polygenic risk scores (PRS) based on an individual's genome sequence are emerging as potentially powerful biomarkers to predict the risk to develop coronary artery disease (CAD). More...
24 Jun 2019
: A tertiary structure of transfer RNA (tRNA) (Photo courtesy of Wikimedia Commons).

Stress-Induced tRNA Fragments Prove Early Predictors of Epileptic Seizures

 Elevated levels of stress-induced fragments of transfer RNA in the blood may serve as biomarkers that indicate potential for an epileptic seizure hours before the event actually occurs. More...
24 Jun 2019
New research showed cfDNA testing was able to accurately identify trisomies in twin pregnancies (Photo courtesy of iStock).

cfDNA Testing Accurately Detects Fetal Trisomies in Twin Pregnancies

 Results presented in a recently published paper indicated that the performance of cfDNA (cell-free DNA) testing for trisomy 21 (Down syndrome) in twin pregnancy was similar to that reported in singleton pregnancy and was superior to that of the firstā€trimester combined test or secondā€trimester biochemical testing. More...
24 Jun 2019
Image: A representation of a methylated DNA molecule. The two white spheres represent methyl groups bound to two cytosine nucleotide molecules (Photo courtesy of Wikimedia Commons).

Disease-Related Epigenetic Variations Summarized in New DNA Methylation Atlas

A new DNA methylation atlas summarized a previously unexplored molecular level of human individuality called correlated regions of systemic interindividual variation (CoRSIVs), which may provide a resource for future population-based investigations into how interindividual epigenetic variation modulates risk of disease. More...
10 Jun 2019
Image: A new liquid biopsy test called DELFI (DNA evaluation of fragments for early interception) uses artificial intelligence to detect patients with cancer by identifying altered DNA fragmentation in the blood (Photo courtesy of Carolyn Hruban, Johns Hopkins University).

Machine Learning Approach Detects Cancer by Analyzing DNA in Blood Samples

Researchers have described a proof-of-principle approach for the screening, early detection, and monitoring of human cancer based on a machine learning approach that evaluates fragmentation patterns of cell-free DNA across the genome. More...
10 Jun 2019


BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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