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BioResearch

Image: Spiked rods of monosodium urate crystals photographed under polarized light from a synovial fluid sample. Formation of monosodium urate crystals in the joints is associated with gout (Photo courtesy of Wikimedia Commons).

Panel of Genetic Loci Accurately Predicts Risk of Developing Gout

A large GWAS (genome-wide association study) highlighted genetic loci associated with the metabolic regulation of serum levels of uric acid (urate) and identified a panel of 183 loci linked to the risk of developing gout. More...
14 Oct 2019
Image: A representation of CEACAM5 protein (Photo courtesy of Wikimedia Commons).

Disrupted TGFB Signaling Linked to Increased Cancer-Related Bacteria

Following careful analysis of DNA sequences collected in The Cancer Genome Atlas, researchers have proposed that CEACAM (carcinoembryonic antigen related cell adhesion molecule) proteins disrupt TGFB signaling, which alters the composition of the intestinal microbiome to promote development of colorectal cancer. More...
14 Oct 2019
Mayo Medical Laboratories
Image: Human Kallikrein 4 (KLK4) protein complexed with nickel and p-aminobenzamidine  (Photo courtesy of Wikimedia Commons).

Gene Fusion Protein Proposed as Prostate Cancer Biomarker

A novel gene fusion product has been proposed as a biomarker for the non-invasive diagnosis of prostate cancer. More...
14 Oct 2019
Image: A ball-and-stick model of the 5-hydroxymethylcytosine (5hmC) molecule (Photo courtesy of Wikimedia Commons).

NIV Test to Diagnose and Monitor Vascular Complications in Diabetes

By applying a sensitive test for analysis of DNA taken from patients with Type II diabetes, researchers were able to diagnose and monitor the presence and severity of diabetic vascular complications such as heart disease, atherosclerosis, and kidney failure. More...
07 Oct 2019
Image: Micrograph of a prostate biopsy showing normal prostatic glands and glands of prostate cancer (prostatic adenocarcinoma) (Photo courtesy of Wikimedia Commons).

Semen Exosome MicroRNA Proves Biomarker for Prostate Cancer

Researchers have shown that microRNAs present in semen exosomes can serve as biomarkers for the non-invasive diagnosis of prostate cancer. More...
07 Oct 2019
Image: The lipodome in connection with the total interactome of a cell (Photo courtesy of Wikimedia Commons).

Genetic Loci Link Plasma Lipid Levels to CVD Risk

A team of Finnish and international researchers utilized both genomics and lipidomics approaches to identify novel genetic variants associated with plasma levels of lipid species and linked these levels to cardiovascular disease (CVD) risk. More...
07 Oct 2019
Image: In a new study, researchers uncovered a gene network that is disrupted in ASD, noting that the disrupted gene network is related to fetal brain development in ASD models (Photo courtesy of University of California, San Diego).

Newly Identified Gene Network Aids in Early Diagnosis of Autism Spectrum Disorder

An improperly functioning molecular network and related biomarkers are expected to help doctors diagnose autism spectrum disorder in young children and to predict the likely severity of symptoms that may develop. More...
30 Sep 2019


BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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