We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




Breath-Based Sampling System Diagnoses Lower Respiratory Tract Infection

By LabMedica International staff writers
Posted on 26 Sep 2024

Lower Respiratory Tract Infections (LRTIs) are the leading cause of death from infectious diseases. More...

Current diagnostic methods rely heavily on clinical symptoms but often lack specificity, particularly given the prevalence of bacterial colonization without active infection. The use of human breath for noninvasive disease detection has long been recognized as a promising diagnostic tool, but the absence of effective biomolecular sampling technologies has limited progress. To overcome this challenge, a new sampling system has been developed to efficiently capture biomolecules from human breath. This system targets protease dysregulation, a known indicator of bacterial infections, by capturing proteases and enabling their activity-based detection, thus aiding in the diagnosis of LRTIs.

ZeteoTech’s (Sykesville, MD, USA) BreathBiomics sampling system introduces an innovative capture mechanism that utilizes advanced surface chemistry to collect non-volatile organic compounds from exhaled breath. The system features chemically modified functional groups designed to have a high affinity for a broad spectrum of biomolecules, including lipids, metabolites, and proteins, allowing for a comprehensive analysis of respiratory health. By leveraging molecular interactions, the system effectively captures biomolecules contained in submicron particles, addressing a significant limitation of existing collection technologies. Additionally, the functional groups can be customized to target specific biomarkers, such as those associated with SARS-CoV-2, offering enhanced flexibility for biomarker detection and diagnosis.

The BreathBiomics sampling system is highly adaptable, integrating seamlessly into various respiratory devices such as facial masks, mouthpieces, mechanical ventilators, oxygen masks, incubators, and tracheostomy tubes. Its quiet operation, generating noise levels below 45 dB (similar to a home refrigerator), makes it ideal for use in clinical environments, including primary care settings, emergency rooms, operating rooms, and intensive care units. Whether used for clinical research or routine care, BreathBiomics has the potential to revolutionize the way clinicians detect and manage respiratory diseases.

Related Links:
ZeteoTech


New
Gold Member
Serological Pipets
INTEGRA Serological Pipets
Serological Pipet Controller
PIPETBOY GENIUS
New
Anti-Thyroid Peroxidase Assay
LIAISON Anti-TPO
New
Silver Member
Quality Control Material
NATtrol Chlamydia trachomatis Positive Control
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








DIASOURCE (A Biovendor Company)

Channels

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: A simple blood test could replace surgical biopsies for early detecion of heart transplant rejection (Photo courtesy of Shutterstock)

Blood Test Detects Organ Rejection in Heart Transplant Patients

Following a heart transplant, patients are required to undergo surgical biopsies so that physicians can assess the possibility of organ rejection. Rejection happens when the recipient’s immune system identifies... Read more

Pathology

view channel
These images illustrate how precision oncology Organ Chips recapitulate individual patients’ responses to chemotherapy (Photo courtesy of Wyss Institute at Harvard University)

Cancer Chip Accurately Predicts Patient-Specific Chemotherapy Response

Esophageal adenocarcinoma (EAC), one of the two primary types of esophageal cancer, ranks as the sixth leading cause of cancer-related deaths worldwide and currently lacks effective targeted therapies.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.