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Image: A multisegment injection-non-aqueous-capillary electrophoresis–mass spectrometer (MSI-NACE-MS) (Photo courtesy of McMaster University)

An Analytical Method to Monitor Dietary Fat Intake

An advanced analytical technique was used to determine unequivocally the composition of fats in the diets of pregnant women and female patients suspected of being deficient in certain dietary fats. More...
25 May 2020
Image: Linking peptide specificities with T cell transcriptomes (Photo courtesy of University of California, Santa Cruz).

High-Throughput T Cell Profiling Technique Developed

T cells recognize foreign or aberrant antigens presented by major histocompatibility complex (MHC-I) expressing cells through the T cell receptor (TCR) and is the first critical step towards establishment of protective immunity against viruses and tumors. More...
13 May 2020
Image: Photograph of the CARMEN microwell chip (Photo courtesy of Michael James Butts)

CRISPR-Based Microarray System Enables Massive Testing for Viral Pathogens

A novel microfluidic nucleic acid-based diagnostic system is capable of detecting a specific virus from a catalog of more than 160 human pathogens, including the COVID-19 coronavirus, simultaneously in more than 1,000 samples. More...
11 May 2020
Image: The positive results of Helicobacter pylori infection by the traditional Giemsa stain. White arrows indicate stained Helicobacter pylori (blue) that are attached to the brush border of the gastric foveolar epithelial cells (Photo courtesy of National Health Research Institutes).

Giemsa Stain Outperforms Urease Test for Helicobacter Pylori Diagnosis

More than 50% of the worldwide population is infected by Helicobacter pylori which is harbored in their upper gastrointestinal tract. Despite having chronic gastritis, most people infected by H. pylori are asymptomatic and have no specific clinical signs and symptoms. More...
05 May 2020
Image: Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging (Photo courtesy of Massachusetts General Hospital Research Institute).

Ultra-Fast Cycling for Multiplexed Cellular Fluorescence Imaging

In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. Until now, analyses of these dynamic changes with conventional biopsies and tissue sections could take days to weeks, or not occur at all prior to treatment. More...
07 Apr 2020
Image:  The SpectraMax M5 Microplate Reader is the standard for UV/visible multi-mode reader absorbance, providing ultrafast, full spectral range detection for cuvettes, 96-, and 384-well microplates (Photo courtesy of Molecular Devices).

Novel Rapid Test Developed for Detecting Carbapenemase

As a potent β-lactamase, carbapenemase can degrade almost all β-lactam antimicrobial drugs, including the carbapenems, regarded as the last line of therapy for many life-threatening infections. If uncontrolled, the spread of these carbapenemases is expected to increase therapeutic failure and leave many patients with no effective treatment options. More...
02 Apr 2020
Image: The high throughput immunochemistry cobas e 801 module (Photo courtesy of Roche Diagnostics).

Novel Method Developed to Estimate LDL Particle Size

Premature atherosclerotic disease commonly occurs in individuals with atherogenic dyslipidemia who share a phenotype characterized by centripetal obesity, insulin resistance, and physical inactivity. Cardiovascular diseases (CVD) are the leading cause of mortality in the Western World being subclinical atherosclerosis the triggering factor for most of these events. More...
01 Apr 2020

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