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Clinical Chemistry

Image: High-sensitivity cardiac troponin I: relying on the sex-specific 99th percentile upper reference limit of cardiac troponin may incorrectly suggest myocardial infarction (MI) in older adults with suspected heart attacks (Photo courtesy of Blood Tests in London)

Age Alters Diagnostic Performance of Cardiac Troponin

The guideline-recommended thresholds for increased high-sensitivity cardiac troponin I (hs-cTnI), indicating myocardial injury and potential infarction, performed at a similar sensitivity around 80% in people across age groups. More...
20 Sep 2022
Image: Blood sample for testosterone hormone test: Low Testosterone Levels Tied to More Severe COVID in Men (Photo courtesy of Rae Lynn Mitchell, MA)

Low Testosterone Levels Tied to More Severe COVID in Men

The COVID-19 pandemic has exacted a heavy toll on public health. Male sex is associated with severe COVID-19. It is not known whether the risk of hospitalization differs between men with hypogonadism, men with eugonadism, and those receiving testosterone therapy (TTh). More...
12 Sep 2022
mage: The AU560 automatic enzymatic analyzer (Photo courtesy of Sysmed Lab Europe)

Osteopontin and Osteoprotegerin Investigated In Peripheral Artery Disease

Peripheral artery disease (PAD) is one of the many complications of systemic atherosclerosis and it is accompanied by high rates of cardiovascular diseases (CVD) morbidity and mortality. PAD is a common condition in which narrowed arteries reduce blood flow to the arms or legs. More...
08 Sep 2022
Image: Results from STORK prenatal genetic test, shown in foreground (Photo courtesy of Columbia University Irving Medical Center).

Prenatal Test Reduces Time of Detecting Chromosomal Abnormalities

A newly developed prenatal test can determine if a fetus or embryo has the right number of chromosomes at a fraction of the time and cost of currently available clinical genetic tests.

More...
24 Aug 2022
Image: The ARCHITECT i2000SR analyzer was used to measure total plasma homocysteine (Photo courtesy of Abbott)

Total Plasma Homocysteine Methods Evaluated

Homocysteine (HCY) is occasionally requested as a prognostic risk factor in patients with cardiovascular diseases. Homocysteine is an intermediary amino acid formed in methionine metabolism, with elevated total homocysteine (tHCY) is a biomarker of cardiovascular and cerebrovascular diseases. More...
15 Aug 2022
Image: Lipid cutoffs defined for increased cardiovascular disease risk in non-diabetic young people (Photo courtesy of Dreamstime)

Lipid Cutoffs Identified for CVD Risk in Young Adults Without Diabetes

The underlying pathogenesis and progression associated with nearly all cardiovascular diseases (CVDs) are predominantly of atherosclerotic origin that leads to the development of coronary artery disease, cerebrovascular disease, venous thromboembolism and, peripheral vascular disease, subsequently causing myocardial infarction (MI), cardiac arrhythmias or stroke. More...
09 Aug 2022
Image: GCC-P portable clinical centrifuge is designed for easy transport (Photo courtesy of Globe Scientific)

Globe Scientific Introduces New Enhanced & Portable Clinical Centrifuges

Globe Scientific, Inc. (Mahwah, NJ, USA) has introduced two new centrifuges to expand on its successful range of benchtop laboratory equipment. More...
03 Aug 2022
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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