We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App

AACC Releases Comprehensive Diabetes Testing Guidelines

By LabMedica International staff writers
Posted on 24 Jul 2023
Print article
Image: New evidence-based guidelines can help diagnose diabetic patients with latest laboratory-analysis tools (Photo courtesy of Freepik)
Image: New evidence-based guidelines can help diagnose diabetic patients with latest laboratory-analysis tools (Photo courtesy of Freepik)

Diabetes, a condition impacting an estimated 537 million people worldwide, is a disorder where the body either underproduces or underutilizes insulin, causing glucose (or sugar) from food to accumulate in the blood. The condition predisposes people to an elevated risk of heart attacks, stroke, vision loss, kidney disease, and other health issues. Now, the American Association for Clinical Chemistry (AACC, Washington, DC, USA), in collaboration with the American Diabetes Association (Arlington, VA, USA), has released evidence-based guidelines to assist in diagnosing and managing patients with diabetes using the most advanced laboratory analysis tools. These updated guidelines stem from an exhaustive evaluation of cutting-edge diabetes laboratory tests' quality and efficacy.

The recently introduced guidelines replace those published in 2002 and 2011 and offer comprehensive updates on continuous glucose monitoring and more accurate guidance for glucose and hemoglobin A1c measurements, which serve as an average blood glucose marker. A multidisciplinary team of medical experts has authored the new guidelines, providing specific, actionable suggestions designed to encourage collaboration among healthcare professionals and improve care for millions of individuals.

One of the key inclusions in the 2023 document is its in-depth guidance regarding continuous glucose monitoring (CGM). With this technology, a device gauges a patient's blood glucose every 5-15 minutes, and an automatic pump dispenses insulin when necessary. The expert panel strongly advocates the use of real-time CGM, coupled with insulin, in certain teenagers and adults with type 1 diabetes—a form of disease where the body fails to produce insulin. The guidance applies to type 1 diabetes patients struggling to meet their blood sugar (glycemic) targets, those unaware of their low blood sugar, and/or those prone to hypoglycemia. While CGM isn't often employed for type 2 diabetes—where the body doesn't utilize insulin effectively—the guidelines recommend healthcare providers consider CGM for insulin-dependent type 2 patients who are not meeting glycemic targets.

The new guidelines also suggest that healthcare professionals use blood collection tubes containing a citrate buffer to prevent glucose breakdown after blood sample collection, as this could compromise measurement accuracy. When these tubes aren't available, an alternative technique involving an ice-water bath and other steps is recommended. According to the guidelines, fasting glucose values above 7.0 mmol/L (>126 mg/dL), and hemoglobin A1c measures of at least 6.5% (>48 mmol/mol), should be deemed indicative of diabetes.

Furthermore, the guidelines offer new guidance for standardizing measurements of insulin and C-peptide—a marker that differentiates between type 1 and type 2 diabetes. The latest updates also cover autoimmune and genetic markers for type 1 diabetes, including a promising gene mutation analysis that can identify rare neonatal diabetes forms. The newly-released guidelines aim to equip the entire healthcare team with the necessary tools to make the most effective clinical decisions by fostering a deeper understanding of lab tests' strengths and limitations.

"It's important to measure accurately—but it's also very important to communicate the relevance to clinicians and to listen to them and share information," said Dr. David Sacks, the guidelines' primary author. "Patient care is a team effort."

Related Links:
American Diabetes Association 

Platinum Member
Flu SARS-CoV-2 Combo Test
OSOM® Flu SARS-CoV-2 Combo Test
Magnetic Bead Separation Modules
POCT Fluorescent Immunoassay Analyzer
Gold Member
Hemoglobin Testing System

Print article



view channel
Image: The Truvian diagnostic platform combines clinical chemistry, immunoassay and hematology testing in a single run (Photo courtesy of Truvian Health)

Automated Benchtop System to Bring Blood Testing To Anyone, Anywhere

Almost all medical decisions are dependent upon laboratory test results, which are essential for disease prevention and the management of chronic illnesses. However, routine blood testing remains limited worldwide.... Read more


view channel
Image: The Simplexa C. auris direct kit is a real-time polymerase chain reaction assay run on the LIAISON MDX instrument (Photo courtesy of Diasorin)

Novel Molecular Test to Help Prevent and Control Multi Drug-Resistant Fungal Pathogen in Healthcare Settings

Candida auris (C. auris) is a rapidly emerging multi drug-resistant fungal pathogen that is commonly found in healthcare environments, where it presents a challenge due to its ability to asymptomatically... Read more


view channel
Image: The tool can improve precision oncology by accurately predicting molecular subtypes and therapy responses (Photo courtesy of Shutterstock)

Computational Tool Integrates Transcriptomic Data for Improved Breast Cancer Diagnosis and Treatment

Breast cancer is the most commonly diagnosed cancer globally, presenting in various subtypes that require precise identification for effective, personalized treatment. Traditionally, cancer subtyping has... Read more


view channel
Image: Beckman Coulter will utilize the ALZpath pTau217 antibody to detect key biomarker for Alzheimer\'s disease on its DxI 9000 immunoassay analyzer (Photo courtesy of Beckman Coulter)

Beckman Coulter Licenses Alzpath's Proprietary P-tau 217 Antibody to Develop Alzheimer's Blood Test

Cognitive assessments have traditionally been the primary method for diagnosing Alzheimer’s disease, but this approach has its limitations as symptoms become apparent only after significant brain changes... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.