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Pathology

Image: uPath PD-L1 (SP263) image analysis (Photo courtesy of Roche)

Roche Advances Personalized Healthcare with Development of Image Analysis Algorithms Using Artificial Intelligence

Roche (Basel, Switzerland) has announced the CE-IVD launch of its automated digital pathology algorithm, the uPath PD-L1 (SP263) image analysis for non-small cell lung cancer (NSCLC). More...
29 Jun 2020
Image: The QIAsymphony SP machine enables sample preparation of DNA, RNA, and bacterial and viral nucleic acids from a wide range of starting materials (Photo courtesy of Qiagen).

Blood Test Predicts Prostate Cancer Treatment Response

Prostate cancer became a bigger killer than breast cancer for the first time, official statistics revealed last year. More than 11,800 men a year - or one every 45 minutes - are now killed by the disease in the UK, compared with about 11,400 women dying of breast cancer. More...
17 Jun 2020
Image: Bacteria (green) inside human pancreatic cancer cells (AsPC-1 cells). The cells’ nuclei are stained blue while their cytoplasm is stained orange (Photo courtesy of Weizmann Institute of Science).

Tumor Microbiome Appears to Vary with Cancer Type

Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear. Bacteria found within tumors were localized within both cancer cells and immune cells and that the bacterial composition varied according to tumor type. More...
11 Jun 2020
Image: Photomicrograph of pediatric pilocytic astrocytoma, a brain tumor, showing the characteristic bipolar cells with long hair-like processes (Photo courtesy of Nephron)

Precision Oncology Confers Clinical Benefit in Relapsed Pediatric Cancer

The Individualized Therapy for Relapsed Malignancies in Childhood (INFORM) registry has been created to help develop precision medicine-based approaches and to analyze their effectiveness across high-risk relapsed or refractory pediatric cancers. More...
08 Jun 2020
Image: Left panel: Histological sections of the left tonsillar tissue found a 2 mm non-keratinizing squamous cell carcinoma, with focal stromal invasion  comparing non-affected area in the left tonsil (Photo courtesy of Queensland University of Technology).

Saliva-Based Assay Developed for HPV-Driven Oropharyngeal Cancer

The incidence of high-risk human papillomavirus (HR-HPV−16, −18, −33) driven oropharyngeal cancer (OPC) is rapidly increasing in developed countries. HPV-driven OPCs have surpassed cervical cancer as the most common HPV-driven cancer in the USA. More...
04 Jun 2020
Image: Schematic diagram of how the representative tumor sampling method lessens bias in molecular analyses (Photo courtesy of Francis Crick Institute).

Representative Tumor Sampling Method Lessens Molecular Analyses Bias

Over the past decade, clinical scientists have demonstrated the inability of an individual biopsy or formalin-fixed paraffin-embedded (FFPE) block to capture the genetic diversity of a solid tumor. More...
25 May 2020
Image: Germline Risk Variants Found in Prostate Cancer Patients Using the Heredity Testing Kit (Photo courtesy of Invitae).

Germline Risk Variants Found in Prostate Cancer Patients

Studies done over the past five years or so have unearthed pathogenic germline variants in some 12% to 17% of men with prostate cancer, and such alterations can impact everything from the treatment options available to them, to the management strategies used for other members of the same family. More...
21 May 2020


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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