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ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.


Image: PathScan Enabler IV Histology/Pathology Digital Slide Scanner (Photo courtesy of Meyer Instruments)

Immunohistochemistry-Guided Sequencing Finds Mutations in Most Cortisol-Producing Adenomas

Cushing syndrome (CS) represents a constellation of signs and symptoms associated with chronic and excessive exposure to glucocorticoids, from either endogenous endocrinopathies or, more commonly, from exogenous pharmacologic sources. More...
27 Apr 2022
Image: BOND-MAX Fully Automated IHC and ISH Staining System (Photo courtesy of LeicaBiosystems)

Single-Cell Proteomics of Localized Prostate Cancer Defines Disease Heterogeneity

Prostate cancer affects about 12.6% of men over the course of their lives, and while most individuals with localized disease can be cured, disease does recur in a small number of patients. The treatment of localized prostate cancer is based on clinicopathological information including Gleason score, prostate-specific antigen (PSA) levels, stage, and patient age. More...
26 Apr 2022
Image: Micrograph of brain tissue with glioma enlargement and disease histology (Photo courtesy of 123rf.com)

Two Simple Serum Biomarkers Differentiate Lymphoma from Glioma

Two simple serum biomarkers, absolute lymphocyte count and prognostic nutritional index, which are easily derived from routine pre-treatment blood tests, have fair correlation and acceptable diagnostic accuracy for differentiating primary central nervous system lymphoma (PCNSL) from high-grade glioma (HGG) in patients with similar morphology on MRI. More...
22 Apr 2022
Image: Testing Neurofilament Light (NF-L) chain in blood samples to monitor neurodegenerative diseases: qualification of an ultrasensitive immuno-assay using clinical serum and plasma samples (Photo courtesy of Advanced BioScience Laboratories, Inc)

Neurofilament Light Biomarker Linked With Parkinson's Disease

Parkinson's disease is caused by a loss of nerve cells in part of the brain called the substantia nigra. This leads to a reduction in a chemical called dopamine in the brain. Blood biomarkers may allow earlier identification of Parkinson’s disease (PD), Parkinsonism, and poor PD-related outcomes, such as physical functioning. More...
19 Apr 2022
Image: Fluidigm CyTOF2 Mass Cytometer (Photo courtesy of University of Minnesota)

Epigenomic Biomarker Predict CAR T-Cell Therapy Resistance in Pediatric Leukemia

Children with acute lymphoblastic leukemia (ALL) whose cells express an epigenomic biomarker rooted in DNA methylation patterns may be less likely to respond to CD19-directed CAR T-cell therapy. More...
18 Apr 2022
Image: Renasight is a test to determine if there is a genetic cause for an individual’s kidney disease or if there is an increased hereditary risk due to family history. The test uses a blood or saliva sample to test 385 genes associated with chronic kidney disease (CKD) (Photo courtesy of Natera)

Broad Gene Panel Diagnoses Patients With Kidney Disease

Chronic kidney disease (CKD) is a major public health issue in the USA. Identification of monogenic causes of CKD, which are present in ∼10% of adult cases, can impact prognosis and patient management. For the ∼800,000 individuals in the USA with end-stage kidney disease (ESKD), genetic diagnosis may inform the selection of potential-related kidney donors, assess the risk of disease recurrence, and guide clinical management following transplant. More...
13 Apr 2022
Image: Digitized pathology slides and associated metadata (Photo courtesy of Pramana, Inc.)

First-of-Its-Kind AI-Enabled Service Digitizes Glass Slides to Help Labs Create Digital Pathology Repositories

Despite the potential value and impact of digitizing pathology archives, few pathology labs have achieved large scale digital libraries. Due to the vastly different slide preparation methods over the years as well as the deterioration of slides in storage, the highly labor-intensive process often results in poor quality and inconsistent images. Now, a vertically integrated solution offers a completely automated means for digitization at scale, enabling significant operational efficiencies by limiting human intervention. More...
25 Mar 2022

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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