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Image: A diagram of circulating tumor cells in a blood sample that can be analyzed for DNA (Photo courtesy of CellMax Life).

Liquid Biopsy Assists with Tumor Treatment Response Monitoring

Non-invasive “liquid biopsies” such as blood tests are growing in use as they help overcome problems of inherent tumor heterogeneity of cancer cells, while providing previously unavailable insight into drug-resistance. They are essential in tracking and monitoring an otherwise intractable disease. More...
19 Jan 2017
Image: The 2200 TapeStation instrument (Photo courtesy of Agilent Technologies).

Vaginal Microbes Denote Early Detection of Endometrial Cancer

Endometrial cancer triggers remain elusive, but given the typical inflammatory profile in these cases, microbes in the uterine environment are suspected to play a role in the development of this disease. More...
19 Jan 2017
BIOHIT  Healthcare OY
Image: The NextSeq 500 Series desktop sequencing system (Photo courtesy of Illumina).

Mutational Profile of Metastatic Breast Cancers Analyzed

Breast cancer often results in poor outcomes after it has metastasized to distant organs, but, while primary breast tumors have been extensively characterized at the molecular level, metastatic lesions are poorly understood. More...
18 Jan 2017
Image: A diagram of the forces on the brain in a coup-contrecoup concussion injury (Image courtesy of Wikimedia).

Brain Protein May Help Assess Recovery Time Following Concussion

An initial study of blood samples from athletes has indicated that elevated levels of the brain protein tau following a sport-related concussion are associated with a longer recovery period and delayed return-to-play (RTP), suggesting that tau may serve as a marker to help physicians determine an athlete’s recovery status and RTP readiness. More...
17 Jan 2017
Image: The BD LSR II flow cytometry analyzer (Photo courtesy of BD Bioscience).

Genetic Test Determines Patients Sensitivity to Cancer Drug

The identification of genetic biomarkers of synthetic lethal drug sensitivity effects provides one approach to the development of targeted cancer therapies. Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs. More...
12 Jan 2017
Image: A diagram of the artificially intelligent nanoarray system to diagnose different diseases from breath analysis (Photo courtesy of the Technion).

Nanoarray Senses and Distinguishes Multiple Diseases

Exhaled breath contains nitrogen, carbon dioxide and oxygen, as well as a small amount of more than 100 other volatile chemical components and the relative amounts of these substances vary depending on the state of a person's health. More...
12 Jan 2017
Image: Overview of the study pipeline beginning with collection of uterine lavage fluid at the initiation of hysteroscopy (Photo courtesy of Icahn School of Medicine at Mount Sinai).

Endometrial Cancer Mutations Detected in Uterine Lavage Fluid

Endometrial cancer is the most common gynecologic malignancy, and its incidence and associated mortality are increasing and despite the immediate need to detect these cancers at an earlier stage, there is no effective screening methodology or protocol for endometrial cancer. More...
11 Jan 2017

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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