We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




Smarter Blood Tests Deliver Faster Diagnoses and Improved Outcomes

By LabMedica International staff writers
Posted on 19 Nov 2024

It has long been established that the earlier a disease is detected, the better the chances for a positive patient outcome. More...

A novel method now offers an in-depth analysis of proteins in plasma, uncovering biomarkers that can help researchers and eventually clinicians identify diseases at an earlier stage.

This pioneering methodology for deep analysis of proteins in plasma was developed by a multidisciplinary team of researchers from Michigan State University (East Lansing, MI, USA), in collaboration with other experts. The new approach minimizes the interference from common blood proteins, making it possible to detect lesser-known, low-abundance proteins that are often key in diagnosing diseases. By introducing small molecules into the blood sample, these important proteins are exposed on the surface of nanoparticles, enhancing their visibility for analysis through mass spectrometry—a technique that separates and examines ionized particles using electric and magnetic fields.

This breakthrough testing method, published in Nature Communications, contributes to the advancement of precision medicine. Unlike the traditional "one-size-fits-all" treatment approach, precision medicine customizes healthcare for an individual's genetics, environment, and lifestyle, offering more targeted and effective solutions. This approach has shown particular promise in fields like cancer research, where tumor genetic profiling can result in improved outcomes and reduced side effects.

“Our innovative approach significantly reduces the masking effects of highly abundant plasma proteins, which often hinder the detection of critical biomarkers in human plasma,” said Morteza Mahmoudi, associate professor in the Department of Radiology and Precision Health Program in the MSU College of Human Medicine. “By minimizing these interactions, we can increase the visibility and identification of low-abundance proteins, making it easier to detect important biomarkers that would otherwise remain hidden. This enhancement leads to improved diagnostic capabilities, allowing for more precise and earlier detection of diseases.”


New
Gold Member
Latex Test
SLE-Latex Test
Serological Pipet Controller
PIPETBOY GENIUS
New
DNA/RNA Extraction/Purification Kit
Nucleic Acid Extraction or Purification Kit
New
Autoimmune Disease Diagnostic
Chorus ds-DNA-G
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








DIASOURCE (A Biovendor Company)

Channels

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: How the predictive test works (Photo courtesy of QMUL)

World’s First Clinical Test Predicts Best Rheumatoid Arthritis Treatment

Rheumatoid arthritis (RA) is a chronic condition affecting 1 in 100 people in the UK today, causing the immune system to attack its joints. Unlike osteoarthritis, which is caused by wear and tear, RA can... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.