We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
RANDOX LABORATORIES

Download Mobile App




Researchers Create Menagerie of Biocompatible Micromachines

By LabMedica International staff writers
Posted on 18 Feb 2019
Print article
Image: Researchers have developed microscopic, hydrogel-based muscles that can manipulate and mechanically stimulate biological tissue. These soft, biocompatible robots could be used for targeted therapy and to help diagnose and prevent disease (Photo courtesy of Nebahat Yenihayat, École Polytechnique Fédérale de Lausanne).
Image: Researchers have developed microscopic, hydrogel-based muscles that can manipulate and mechanically stimulate biological tissue. These soft, biocompatible robots could be used for targeted therapy and to help diagnose and prevent disease (Photo courtesy of Nebahat Yenihayat, École Polytechnique Fédérale de Lausanne).
A team of Swiss biotech engineers has demonstrated possible medical applications for biocompatible micromachines constructed from gold nanorods coated with a thermoresponsive polymer.

Investigators at École Polytechnique Fédérale de Lausanne (Switzerland) combined several advanced techniques including programmable colloidal self-assembly, light-harvesting with plasmonic nanotransducers, and in situ polymerization of compliant hydrogel mechanisms to build biologically inspired, soft microelectromechanical systems (MEMS) devices. These optomechanical microactuators were synthesized using a template-assisted microfluidic approach in which gold nanorods coated with a thermoresponsive polymer functioned as nanoscale building blocks.

The investigators reported in the February 4, 2019, online edition of the journal Lab on a Chip that near-infrared (NIR) laser illumination provided effective control over actuation of the resulting microactuators. These micromachines exhibited mechanical properties and performance characteristics that were comparable to those of bioengineered muscular constructs.

The investigators demonstrated the versatility of this approach by manufacturing a diverse array of microdevices including lever arms, continuum microrobots, and dexterous microgrippers.

"We wanted to create a modular system powered by the contraction of distributed actuators and the deformation of compliant mechanisms," said senior author Dr. Selman Sakar, an assistant professor in the institute of mechanical engineering at École Polytechnique Fédérale de Lausanne.

Related Links:
École Polytechnique Fédérale de Lausanne

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Magnetic Bead Separation Modules
MAG and HEATMAG
POCT Fluorescent Immunoassay Analyzer
FIA Go
New
Gold Member
Fully Automated Cell Density/Viability Analyzer
BioProfile FAST CDV

Print article

Channels

Clinical Chemistry

view channel
Image: The 3D printed miniature ionizer is a key component of a mass spectrometer (Photo courtesy of MIT)

3D Printed Point-Of-Care Mass Spectrometer Outperforms State-Of-The-Art Models

Mass spectrometry is a precise technique for identifying the chemical components of a sample and has significant potential for monitoring chronic illness health states, such as measuring hormone levels... Read more

Hematology

view channel
Image: The CAPILLARYS 3 DBS devices have received U.S. FDA 510(k) clearance (Photo courtesy of Sebia)

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Hemoglobinopathies, the most widespread inherited conditions globally, affect about 7% of the population as carriers, with 2.7% of newborns being born with these conditions. The spectrum of clinical manifestations... Read more

Immunology

view channel
Image: A false color scanning election micrograph of lung cancer cells grown in culture (Photo courtesy of Anne Weston)

AI Tool Precisely Matches Cancer Drugs to Patients Using Information from Each Tumor Cell

Current strategies for matching cancer patients with specific treatments often depend on bulk sequencing of tumor DNA and RNA, which provides an average profile from all cells within a tumor sample.... Read more

Microbiology

view channel
Image: Microscope image showing human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color (Photo courtesy of Fred Hutch Cancer Center)

Mouth Bacteria Test Could Predict Colon Cancer Progression

Colon cancer, a relatively common but challenging disease to diagnose, requires confirmation through a colonoscopy or surgery. Recently, there has been a worrying increase in colon cancer rates among younger... Read more

Pathology

view channel
Image: Fingertip blood sample collection on the Babson Handwarmer (Photo courtesy of Babson Diagnostics)

Unique Hand-Warming Technology Supports High-Quality Fingertip Blood Sample Collection

Warming the hand is an effective way to facilitate blood collection from a fingertip, yet off-the-shelf solutions often do not fulfill laboratory requirements. Now, a unique hand-warming technology has... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.