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Molecular Diagnostics

Image: An artist`s conception of nanodiamonds used for in vitro diagnostics (Photo courtesy of Ella Maru Studio, University College London)

Nanodiamonds Dramatically Boost Immunoassay Sensitivity

Incorporation of a specific class of nanodiamond into lateral flow immunoassays was shown to increase the sensitivity of this method by at least five orders of magnitude. More...
08 Dec 2020
Image: Abnormal accumulation of tau protein in neuronal cell bodies (arrow) and neuronal extensions (arrowhead) in the neocortex of a patient who had died with Alzheimer`s disease (Photo courtesy of Wikimedia Commons)

Some Phosphorylated Tau Proteins Indicate Alzheimer’s Disease Prior to Appearance of Cognitive Impairment

Determination of some specific types of phosphorylated tau proteins enables detection of Alzheimer’s disease before development of cognitive impairment. More...
08 Dec 2020
Image: Rare genetic differences play vital role in regulating blood pressure (Photo courtesy of British Heart Foundation).

Rare Variants Associated with Blood Pressure Regulation

Genes likely play some role in high blood pressure, heart disease, and other related conditions. However, it is also likely that people with a family history of high blood pressure share common environmental and other potential factors that increase their risk. More...
07 Dec 2020
Image: A recently developed device enables faster testing of antibiotic-resistant bacteria (Photo courtesy of Dr. Seokheun `Sean` Choi)

Fast Antibacterial Susceptibility Testing by Measuring Electron Transfer Metabolism

A recently developed device facilitates bacterial antibiotics susceptibility testing by measuring the effect of these drugs on bacterial electron transfer metabolism. More...
07 Dec 2020
Image: The Tapestri Platform is the first and only single-cell multi-omics platform that is capable of simultaneously providing both genotype and phenotype data from the same cell, across thousands of cells (Photo courtesy of Mission Bio).

Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies

Myeloid malignancies are clonal diseases of hematopoietic stem or progenitor cells. Myeloid malignancies, including acute myeloid leukemia (AML), arise from the expansion of these hematopoietic stem and progenitor cells that acquire somatic mutations. More...
01 Dec 2020
Image: Lung cells infected with coronavirus (Photo courtesy of The Hebrew University of Jerusalem).

SARS-CoV-2 RNA Test Assessed Among Recovered COVID-19 Patients

Some patients who have recovered from coronavirus disease 2019 (COVID-19) with documented negative real-time polymerase chain reaction (RT-PCR) results at the time of recovery have had subsequent positive RT-PCR test results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). More...
25 Nov 2020
Image: Micrograph showing fibrosis of the liver caused by cirrhosis. The tissue in this example is stained with a trichrome stain, in which fibrosis is colored blue. The red areas are the nodular liver tissue (Photo courtesy of Wikimedia Commons)

Panel of Urinary Peptides Used to Diagnose Liver Fibrosis

A panel of 50 urinary peptides was shown to be a useful tool for the early diagnosis of liver fibrosis. More...
24 Nov 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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