We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App




Bench-Top Robotic Cell-Free DNA Extraction Workstation Automates NIPT Workflows

By LabMedica International staff writers
Posted on 06 Sep 2023
Print article
Image: The MagBench automated DNA extraction instrument (Photo courtesy of Yourgene Health)
Image: The MagBench automated DNA extraction instrument (Photo courtesy of Yourgene Health)

Yourgene Health (Manchester, UK) has launched the Yourgene MagBench Automated DNA Extraction Instrument and Kit, designed to provide clinical laboratories with an efficient and cost-effective bench-top robotic workstation for cell-free DNA (cfDNA) extraction. This system is specifically optimized for Yourgene's Sage 32 NIPT Workflow, offering a comprehensive end-to-end solution, from sample handling to generating reports. This integrated approach enables clinical laboratories to offer a more accurate and competitive non-invasive prenatal testing (NIPT) service.

The Sage Prenatal Screen, a key component of this workflow, facilitates the safe and accurate genetic assessment of placental DNA in maternal blood using next-generation sequencing, delivering results within three days. The NIPT workflow begins with the extraction of DNA from maternal plasma using the MagBench instrument. Subsequent steps include library preparation, enrichment, sequencing, and Sage Link analysis, which estimates the risk of fetal trisomy 21, 18, or 13, rare autosomal aneuploidies, sex chromosome aneuploidies, and clinically significant microdeletions.

The MagBench Automated DNA Extraction Instrument is user-friendly, quick to install, and features an intuitive touchscreen interface with pre-programmed protocols. It offers efficient run times and flexible sample throughput to meet the laboratory's testing requirements. The MagBench Extraction Kit includes sample and elution tubes, pre-sealed cartridges containing all necessary reagents for cfDNA purification, and individually packaged tip sets with a unique cross-notch design to ensure precise volume pipetting. This system enhances the automation of DNA extraction, reducing manual intervention and the risk of human error. Additionally, it incorporates single-use tip disposal and a built-in UV lamp for decontamination between runs, thereby minimizing the potential for cross-contamination. These features collectively contribute to improved pipetting accuracy and consistency, resulting in a reduced failure rate. The MagBench solution is available to Sage customers in the Asia-Pacific and Middle East regions.

“Yourgene is committed to delivering best-in-class NIPT solutions, where precision and quality assurance are key,” said Dr. Rob Henke, Vice President of Sales, Asia-Pacific at Yourgene Health. “MagBench enables an economical and automated NIPT workflow. Reducing manual procedures improves user experience, facilitating true walkaway time while minimizing the risk of contamination and improving testing accuracy. This decreases the number of screening failures, greatly improves efficiency, and helps lower expectant parents’ anxiety.”

Related Links:
Yourgene Health

New
Platinum Member
Flu SARS-CoV-2 Combo Test
OSOM® Flu SARS-CoV-2 Combo Test
Magnetic Bead Separation Modules
MAG and HEATMAG
POCT Fluorescent Immunoassay Analyzer
FIA Go
New
Gold Member
Fully Automated Cell Density/Viability Analyzer
BioProfile FAST CDV

Print article

Channels

Clinical Chemistry

view channel
Image: The new ADLM guidance will help healthcare professionals navigate respiratory virus testing in a post-COVID world (Photo courtesy of 123RF)

New ADLM Guidance Provides Expert Recommendations on Clinical Testing For Respiratory Viral Infections

Respiratory tract infections, predominantly caused by viral pathogens, are a common reason for healthcare visits. Accurate and swift diagnosis of these infections is essential for optimal patient management.... Read more

Hematology

view channel
Image: The CAPILLARYS 3 DBS devices have received U.S. FDA 510(k) clearance (Photo courtesy of Sebia)

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Hemoglobinopathies, the most widespread inherited conditions globally, affect about 7% of the population as carriers, with 2.7% of newborns being born with these conditions. The spectrum of clinical manifestations... Read more

Microbiology

view channel
Image: The POC PCR test shortens time for STI test results (Photo courtesy of Visby Medical)

POC STI Test Shortens Time from ED Arrival to Test Results

In a 2024 sexually transmitted infections (STIs) surveillance report by the World Health Organization (WHO), over 2.5 million cases were recorded, alongside a rise in the inappropriate use of antibiotics... Read more

Industry

view channel
Image: For 46 years, Roche and Hitachi have collaborated to deliver innovative diagnostic solutions (Photo courtesy of Roche)

Roche and Hitachi High-Tech Extend 46-Year Partnership for Breakthroughs in Diagnostic Testing

Roche (Basel, Switzerland) and Hitachi High-Tech (Tokyo, Japan) have renewed their collaboration agreement, committing to a further 10 years of partnership. This extension brings together their long-standing... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.