We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




Molecular Diagnostic Chip Targets Multidrug Resistant Tuberculosis

By LabMedica International staff writers
Posted on 29 Nov 2012
A multiplexed molecular diagnostic chip is capable of fast and accurate detection of Mycobacterium Tuberculosis Complex (MTBC) and its mutations, as well as nine other clinically important nontubercular Mycobacteria.

The newly launched Lab-on-Chip platform, marketed by Veredus Laboratories (Singapore) as the VerePLEX biosystem, combines Micro-Electro-Mechanical-Systems (MEMS) with microfluidics, to integrate multiplexed DNA amplification with microarray detection for rapid, cost-effective, and accurate analysis of biological materials.

The mutations in M. More...
tuberculosis are responsible for its resistance to multiple drugs and for the global spread of Tuberculosis (TB). The rise of multidrug-resistant TB is a global healthcare challenge. Effective treatment of TB involves accurate and fast diagnosis followed by a strict regimen of the appropriate drugs. Shortcomings in this treatment can cause the TB organism to mutate into drug-resistant strains that can become increasingly difficult and expensive to treat.

Conventional methods of accurately identifying TB infections can take up to 8 weeks. In contrast, VereMTB can complete the diagnosis and identify the specific Mycobacterium causing the infection and drug resistance in less than 3 hours from natural samples, avoiding the need for culturing, the most time-consuming part of the traditional method. Additionally due to its compact size, the system can be deployed in a wide range of settings at point-of-need. “Natural samples” refer to direct sputum coughed out by TB patients.

The VereMTB chip is currently undergoing evaluations by the Chinese Center for Disease Control and Prevention (Beijing, China) as part of their ongoing program to assess new technologies for TB diagnostics. According to the 2012 World Health Organization report on TB, India and China combined have almost 40% of the world’s TB cases. Nearly 60% of multidrug resistant cases in 2011 were found in India, China, and the Russian Federation.

Related Links:

Veredus Laboratories



Gold Member
Quantitative POC Immunoassay Analyzer
EASY READER+
Serological Pipet Controller
PIPETBOY GENIUS
New
Silver Member
Autoimmune Hepatitis Test
LKM-1-Ab ELISA
New
Silver Member
Quality Control Material
NATtrol Chlamydia trachomatis Positive Control
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








DIASOURCE (A Biovendor Company)

Channels

Hematology

view channel
Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Immunology

view channel
Image: A simple blood test could replace surgical biopsies for early detecion of heart transplant rejection (Photo courtesy of Shutterstock)

Blood Test Detects Organ Rejection in Heart Transplant Patients

Following a heart transplant, patients are required to undergo surgical biopsies so that physicians can assess the possibility of organ rejection. Rejection happens when the recipient’s immune system identifies... Read more

Pathology

view channel
These images illustrate how precision oncology Organ Chips recapitulate individual patients’ responses to chemotherapy (Photo courtesy of Wyss Institute at Harvard University)

Cancer Chip Accurately Predicts Patient-Specific Chemotherapy Response

Esophageal adenocarcinoma (EAC), one of the two primary types of esophageal cancer, ranks as the sixth leading cause of cancer-related deaths worldwide and currently lacks effective targeted therapies.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.