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Clinical Chemistry

Image: The Lucica Glycated Albumin-L assay is a new diagnostic test for measuring GA. The test is based on an enzymatic method that uses liquid reagents requiring no preparation (Photo courtesy of Asahi Kasei Pharma Corporation)

Analytical Performance of Novel Glycated Albumin Assay Evaluated

Diabetes is a complex, chronic illness requiring continuous medical care with multifactorial risk-reduction strategies beyond glycemic control. Hemoglobin A1c (HbA1c) reflects the concentration of mean plasma glucose (MPG) over the last 2–3 months and has been the gold standard for monitoring glycemic control of diabetic patients in clinical practice. More...
26 May 2022
Image: UltiMate 3000 RSLCnano System: this low-flow liquid chromatography system has a wide flow-pressure footprint with nano-, capillary-, and micro-flow options (Photo courtesy of Thermo Fisher Scientific)

Different Subtypes Defined In Small Cell Lung Cancer

Small cell lung cancer (SCLC) is a malignant disease associated with a particularly high mortality rate. SCLC is a particularly aggressive cancer that typically occurs in smokers, exhibiting rapid growth and a high propensity for metastasis. More...
25 May 2022
Image: The DetectX Butyrylcholinesterase (BChE) Fluorescent Activity Kit measures BChE activity in a wide variety of samples, utilizing a proprietary non-fluorescent molecule, ThioStar, which fluoresces when bound to the thiol reaction product of BChE and its substrate (Photo courtesy of Arbor Assays)

Potential Biomarker Found for Sudden Infant Death Syndrome

The term Sudden Unexpected Death in Infancy (SUDI) covers both explained and unexplained deaths. The unexplained deaths are termed Sudden Infant Death Syndrome (SIDS). Despite intensive studies over the past decades, the mechanisms which lead to SIDS remain elusive. More...
23 May 2022
Image: The Sysmex XE-2100D automated hematology analyzer (Photo courtesy of Bimedis)

Complete Blood Count Parameters Associated With Pancreatic Beta-Cell Function

The pathophysiology of type 2 diabetes mellitus (T2DM) involves insulin resistance (IR) and progressive deterioration of beta-cell function (BCF). Estimation of IR and BCF is essential for screening subjects at a high risk of T2DM and making treatment plans in clinical practice. More...
19 May 2022
Image: The analysis pipeline used to investigate associations between blood metabolites, later life brain imaging measures, and genetic risk for Alzheimer’s disease (Photo courtesy of University College London)

Lipid Measurements Show Potential as Alzheimer’s Disease Biomarkers

Brain changes accompanying ageing are varied and can include pathologies that lead to cognitive impairment, the commonest of which is Alzheimer’s disease (AD). Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. More...
17 May 2022
Image: The new BS-600M chemistry analyzer provides a complete package to help labs grow (Photo courtesy of Mindray)

Mindray Launches High Throughput BS-600M Chemistry Analyzer with Industry-Leading Small Footprint

Mindray (Shenzhen, China) has launched the new BS-600M, a powerful yet efficient chemistry analyzer designed to empower medium-volume laboratories with increased productivity, efficiency and reliability. More...
16 May 2022
Image: ROC curve AUC and levels of Proenkephalin A 119–159 (PENK) 48 hours after liver transplantation in the need-renal replacement therapy groups (Photo courtesy of University of Sao Paulo)

Biomarker Proenkephalin Investigated in Diagnosis of Acute Kidney Injury

Liver transplantation (LT) is the only treatment available for patients with end-stage liver disease, such as liver cancer or acute and subacute liver failure. Among the various types of postoperative organ damage, acute kidney injury (AKI) is particularly prevalent, developing in 5% to 20% of patients undergoing major non-cardiac surgery. More...
12 May 2022
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.

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