We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Technopath Clinical Diagnostics - An LGC Company

Download Mobile App





3D Printing Paves Way for New Type of COVID-19 Lateral Flow Test with More Capabilities

By LabMedica International staff writers
Posted on 11 May 2021
Print article
Image: 3D Printing Paves Way for New Type of COVID-19 Lateral Flow Test with More Capabilities (Photo courtesy of Ameloot Group)
Image: 3D Printing Paves Way for New Type of COVID-19 Lateral Flow Test with More Capabilities (Photo courtesy of Ameloot Group)
Researchers have developed a 3D printing technique that extends the possibilities of COVID-19 lateral flow tests and enable production of quick, cheap, and easy to use advanced diagnostic tests.

Using a 3D printer, bioengineers at KU Leuven (Leuven, Belgium) have fabricated a 3D version of a lateral flow test. The basis is a small block of porous polymer, in which ‘inks’ with specific properties are printed at precise locations. In this way, a network of channels and small ‘locks’ is printed that let the flow through or block it where and when necessary, without the need for moving parts. During the test, the sample is automatically guided through the different test steps. That way, even complex protocols can be followed.

The researchers evaluated their technique reproducing an ELISA test (Enzyme-Linked Immunosorbent Assay), which is used to detect immunoglobulin E (IgE). Ig E is measured to diagnose allergies. In the lab, this test requires several steps, with different rinses and a change in acidity. The research team was able to run this entire protocol using a printed test kit the size of a thick credit card. The technique not only offers opportunities for cheaper and faster diagnosis in developed countries, but also in countries where the medical infrastructure is less accessible and where there is a strong need for affordable diagnostic tests. The 3D printing technique is also affordable and scalable.

“The great thing about 3D printing is that you can quickly adapt a test’s design to accommodate another protocol, for example, to detect a cancer biomarker. For the 3D printer it does not matter how complex the network of channels is,” said Dr. Cesar Parra. “In our lab, producing the Ig E prototype test costs about USD 1.50, but if we can scale it up, it would be less than USD 1.”

Related Links:
KU Leuven

Gold Supplier
Flu A/Flu B/ SARS-CoV-2 Antigen Test (Colloidal Gold)
One Step Test for Flu A/Flu B/ SARS-CoV-2 Antigen
New
Zika Virus ELISA Test
RecombiLISA Zika IgM ELISA CE
New
Gold Supplier
Automatic Western Blot Analyzer
Tenfly Phoenix Blot Analyzer
New
Gold Supplier
Bartonella Immunofluorescence Assay
BARTONELLA IFA

Print article

Channels

Molecular Diagnostics

view channel
Image: The new multiplex QIAstat-Dx Viral Vesicular Panel is designed to support research and surveillance efforts (Photo courtesy of QIAGEN)

First Syndromic Test Differentiates Between Monkeypox and Five Pathogens with Similar Symptoms

A new syndromic test differentiates between monkeypox and five other pathogens which cause similar symptoms. This first-ever test detects the two known forms of monkeypox virus (the so-called West African... Read more

Industry

view channel
Image: The Accelerate Arc Module & BC kit is registered as an IVD (Photo courtesy of Accelerate Diagnostics)

BD and Accelerate Diagnostics Collaborate to Offer Rapid Antimicrobial Identification and Susceptibility Diagnostics

Becton, Dickinson and Company (BD, Franklin Lakes, NJ, USA) and Accelerate Diagnostics, Inc. (Tucson, AZ, USA) have entered into a worldwide commercial collaboration agreement where BD will offer Accelerate's... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.