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Clinical Chemistry

Image: Schematic diagram of deep vein thrombosis (DVT) that is associated with metabolic syndrome (Photo courtesy of MediConnect).

Metabolic Syndrome Associated with Increased Blood Clot Recurrence Risk

 People with metabolic syndrome which are a set of conditions including obesity, impaired glucose metabolism, elevated levels of fats and cholesterol in the blood, and high blood pressure, are more likely to experience recurrent blood clots. More...
21 Jan 2020
Image: Histopathology of Leptomeningeal Melanoma Metastases: tumor cell clusters in the subarachnoid space in a brain biopsy (Photo courtesy of selbst).

Molecular Characteristics of Leptomeningeal Melanoma Metastases Identified

 Patients with advanced melanoma who develop metastases in the leptomeninges, the fluid filled membranes surrounding the brain and spinal cord, have an extremely poor prognosis. Most patients only survive for eight to 10 weeks after diagnosis. More...
20 Jan 2020
Image: Synergy H1 Hybrid Multi-Mode Reader is a configurable microplate reader (Photo courtesy of BioTek)

Higher Female TSH Associated With Lower Mannan-Binding Lectin

 Mannan-binding lectin (MBL) is a main component of the lectin pathway of the complement system. Lower MBL levels are associated with, among other conditions, hypothyroidism and adverse pregnancy outcomes. More...
15 Jan 2020
Image: Immunoassay for the in vitro quantitative determination of NT-proBNP in heparinized venous blood for use with the cobas h 232 instrument (Photo courtesy of Axonlab)

Cardiac Blood Test Predicts Post-Surgical Outcomes

 Globally, of the 200 million adults who undergo major surgery, 18% will experience serious cardiac and vascular complications including death within 30 days following their intervention, such as hip and knee replacements, bowel resections and abdominal aortic aneurysm repair. More...
08 Jan 2020
Image: Design of the CareStart G6PD deficiency screening test and interpretation of the results:  Panel A, no color change for sample with deficient G6PD enzymatic activity; Panel B, distinct purple color for sample with normal G6PD enzymatic activity (Photo courtesy of Charles Darwin University).

Rapid Diagnostic Test for The Detection of G6PD Deficiency Evaluated

 To reduce the risk of drug-induced hemolysis, all patients should be tested for glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PDd) prior to prescribing primaquine (PQ)-based radical cure for the treatment of vivax malaria. More...
07 Jan 2020
Image: The PATHFAST system combines the accuracy of a full-scale laboratory analyzer with the flexibility of a mobile solution (Photo courtesy of LSI Medience Corporation)

Presepsin Concentrations Predicts Commensurate Decline in Kidney Function

 Chronic kidney disease (CKD) is a worldwide health problem and its prevalence is rising, particularly in the elderly, mainly reflecting the increased life expectancy of the global population. Decrease in nephron number with aging leads to age-related decline in glomerular filtration rate (GFR). More...
06 Jan 2020
Image: Biochemical markers in blood samples are affected by adiposity in children (Photo courtesy of Photo Tom Mallinson).

Biochemical Markers Affected by Adiposity in Children

 Pediatric or childhood obesity is the most prevalent nutritional disorder among children and adolescents worldwide. Approximately 43 million individuals are obese, 21%–24% children and adolescents are overweight, and 16%–18% of individuals have abdominal obesity. More...
02 Jan 2020
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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