We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
INTEGRA BIOSCIENCES AG

Download Mobile App





New Non-Invasive Saliva Test for Early and Accurate Detection of Prostate Cancer Presented at AACC 2021

By LabMedica International staff writers
Posted on 28 Sep 2021
Print article
Illustration
Illustration

A new non-invasive test that uses saliva samples to accurately diagnose cases of prostate cancer was presented at the 2021 AACC Annual Scientific Meeting & Clinical Lab Expo.

The test developed by researchers at the Tehran University of Medical Sciences (Tehran, Iran) could allow clinicians to better distinguish early-stage prostate cancer from more benign prostate conditions.

A key challenge in cancer care is the diagnosis of prostate cancer, one of the most common cancers in men. Clinicians currently use invasive biopsies or tests for prostate-specific antigen levels to diagnose prostate cancer in the clinic. But prostate cancer can be hard to spot during the early stages and can be tricky to distinguish from benign prostatic hyperplasia (BPH), a benign enlargement of the prostate that can appear as men age.

In an effort to solve these issues, researchers have developed a new test for prostate cancer that uses saliva samples, which can be collected repeatedly and non-invasively. Their test distinguishes prostate cancer from BPH by testing saliva for eight different microRNAs that either support or suppress tumor growth. The researchers validated their test with saliva samples from 180 men between 45 and 50 years of age, 60 of whom had been diagnosed with prostate cancer using standard methods and 60 of whom had been diagnosed with BPH.

“The advantage of our study is the use of several microRNAs, which have been reported to be detectable in the blood much earlier than the progression of cancer, which makes for a better diagnosis, as well as the use of saliva as a non-invasive biological sample that causes little pain to patients,” said Dr. Jamal Amri of the Tehran University of Medical Sciences.

Related Links:
Tehran University of Medical Sciences 

Gold Member
Troponin T QC
Troponin T Quality Control
New
Gold Member
Chagas Disease Test
CHAGAS Cassette
New
Zonulin ELISA
IDK Zonulin (Serum) ELISA
New
Gold Member
Human Chorionic Gonadotropin Test
b-hCG Cassette

Print article
ADLM

Channels

Immunology

view channel
Image: Example image of the high-throughput microscopy method used in the study, showing immune cells stained with different fluorescence markers (Photo courtesy of Felix Kartnig/CeMM, MedUni Vienna)

Cutting-Edge Microscopy Technology Enables Tailored Rheumatology Therapies

Rheumatoid arthritis is the most common inflammatory joint disorder, with women three times as likely to suffer from the condition as men. Treatment advances made over the past decades have led to the... Read more

Microbiology

view channel
Image: RNA sequencing directly from whole blood aims to expand access to LRTI testing (Photo courtesy of CARB-X)

Novel Test to Diagnose Bacterial Pneumonia Directly from Whole Blood

Pneumonia and lower-respiratory-tract infections (LRTIs) are among the top causes of illness and death globally, particularly in vulnerable populations such as the elderly, young children, and immunocompromised... Read more

Pathology

view channel
Image: The new method uses DNA sequencing to measure metabolites (Photo courtesy of 123RF)

New Metabolite Detection Method Using DNA Sequencing Could Transform Diagnostics

Metabolites play a vital role as biomarkers that provide insights into our health, and when their levels go awry, it can lead to diseases such as diabetes and phenylketonuria. Quantifying metabolites remains... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.