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Technology

Image: Paper-based diagnostic device that detects biomarkers and identifies diseases by performing electrochemical analyses. The assays change color to indicate specific test results. The device can be plugged into the handheld potentiostat, at left (Photo courtesy of Purdue University, Aniket Pal).

Disposable POC Device Introduced for Low-Resource Areas

A recent paper described a novel diagnostic device fabricated from various types of paper to be used for point-of-care testing in areas lacking electricity and other resources. More...
05 Sep 2017
Image: A representative picture of Giemsa-stained hydrophilic-treated COC plates; Arrows indicate Plasmodium-infected cells (Photo courtesy of National Institute of Advanced Industrial Science and Technology).

Malaria Diagnosis Employs Hydrophilic-Treated Plastic Plates

Malaria is a red blood cell (RBC) infection caused by Plasmodium parasite and to determine RBC infection rate, which is essential for malaria study and diagnosis, microscopic evaluation of Giemsa-stained thin blood smears on glass slides is performed. More...
30 Aug 2017
Image: Klebsiella pneumoniae growing in the microfluidic chip imaged in phase contrast. The bacteria are 3 µm long and divide every 30 minutes (Photo courtesy of Özden Baltekina et al).

New Ultrafast Method Determines Antibiotic Resistance

Antibiotic resistance is a growing medical problem that threatens human health globally. One important contributory factor in the development of resistance is the incorrect use of antibiotics for treatment. More...
24 Aug 2017
Image: The spectral transmission-reflectance-intensity (TRI)-Analyzer attaches to a smartphone and analyzes patient blood, urine, or saliva samples as reliably as clinic-based instruments that cost thousands of dollars (Photo courtesy of the Department of Bioengineering, University of Illinois at Urbana-Champaign).

Smartphone-Based Analyzer Designed for Sample Testing

A handheld spectrophotometer that uses a smartphone camera to measure changes in absorption of natural light or emission of fluorescent light is the key to a mobile instrument that can evaluate biological samples with the accuracy of clinical laboratory analyzers but at a fraction of the cost. More...
21 Aug 2017
Image: A bioplasmonic paper-based device (BPD) for the detection of Zika virus (ZIKV) infection, via quantification of serum anti-ZIKV-nonstructural protein 1 (NS1) IgG and IgM (Photo courtesy of James Byard).

Biosensor Device Developed for Zika Diagnosis

A novel plasmonic biosensor-based detection system was developed that can diagnose recent or current Zika virus (ZIKV) infection in 15 minutes or less. More...
21 Aug 2017
Image: A prototype of the D4 assay (Photo courtesy of Daniel Joh, Duke University).

Smartphone-Based ELISA Developed for Blood Antigens

A novel high speed, lab-on-a-chip ELISA test for antigens in blood samples depends on a unique nonstick polymer coating that eliminates the need for multiple incubation and washing steps. More...
14 Aug 2017

Dried Blood Assessment Equivalent to Drawn Blood Samples

A self-sampling method for therapeutic drug monitoring (TDM) of biologicals was developed that should enhance TDM implementation by patients with various autoimmune conditions. More...
14 Aug 2017
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