We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




Blood Test Accurately Detects Circulating Tumor-Related Mutations

By LabMedica International staff writers
Posted on 23 Jan 2025

In patients undergoing initial anticancer treatments, some tumor cells can survive and remain in their bodies. More...

This low 'disease burden' can cause a relapse, which traditional genomic and imaging methods can fail to detect. Timely detection of this 'minimal residual disease' is vital for reducing recurrence risks. Now, a novel blood test combines tumor-informed and tumor-agnostic molecular features for personalized, accurate, and more effective monitoring of molecular residual disease (MRD).

Datar Cancer Genetics (DCG, London, UK) has launched Target-MRD, an advanced MRD monitoring blood test designed for solid organ cancers. Target-MRD is a blood test based on tumor-agnostic next-generation sequencing (NGS) and customized, tumor-informed droplet digital PCR (dd-PCR) assay. Target-MRD provides personalized, ultra-sensitive detection and monitoring of residual disease at the molecular level, if any, to enable early intervention by oncologists, much before the disease becomes unmanageable. Target-MRD combines tumor-agnostic (to detect tumor evolution) and tumor-informed (specific to a patient's cancer) biomarkers, thus providing a comprehensive and ultra-high sensitivity solution for more effective disease management.

Monitoring the slightest recurrence of cancer in patients after treatment is vital to allow for timely interventions before the disease becomes unmanageable. Target-MRD’s dual approach marks a significant step forward in the non-invasive detection of the earliest signs of residual disease. The test offers the potential to transform the management of cancer patients. This novel MRD detection approach that combines tumor-informed and tumor-agnostic strategies is a significant advancement in oncology diagnostics. This innovative methodology enables truly personalized care for cancer patients. With its sensitivity and precision, clinicians have access to invaluable tools for personalizing treatments, improving detection of recurrence, and optimizing long-term patient outcomes.

"Target-MRD reflects DCG's commitment to safe, reliable, and accurate technologies. It is the next generation test that has the potential not only to detect recurrence earlier but to adapt itself to each patient's individual requirements and helps to personalize cancer management decisions," said Dr. Darshana Patil, Senior Director, Global Strategy and Medical Affairs at DCG. "With its ability to sensitively detect minimal residual disease, Target-MRD empowers clinicians with the information they need to make timely, data-driven decisions, improving patient outcomes and ultimately transforming the way cancer is managed."

Related Links:
DCG


Gold Member
Antipsychotic TDM Assays
Saladax Antipsychotic Assays
Collection and Transport System
PurSafe Plus®
New
Autoimmune Liver Diseases Assay
Microblot-Array Liver Profile Kit
New
Clinical Chemistry System
P780
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Hematology

view channel
Image: New research points to protecting blood during radiation therapy (Photo courtesy of 123RF)

Pioneering Model Measures Radiation Exposure in Blood for Precise Cancer Treatments

Scientists have long focused on protecting organs near tumors during radiotherapy, but blood — a vital, circulating tissue — has largely been excluded from dose calculations. Each blood cell passing through... Read more

Pathology

view channel
Image: Erythrocyte Sedimentation Rate Sample Stability (Photo courtesy of ALCOR Scientific)

ESR Testing Breakthrough Extends Blood Sample Stability from 4 to 28 Hours

Erythrocyte sedimentation rate (ESR) is one of the most widely ordered blood tests worldwide, helping clinicians detect and monitor infections, autoimmune conditions, cancers, and other diseases.... Read more

Technology

view channel
Image: Conceptual design of the CORAL capsule for microbial sampling in the small intestine (H. Mohammed et al., Device (2025). DOI: 10.1016/j.device.2025.100904)

Coral-Inspired Capsule Samples Hidden Bacteria from Small Intestine

The gut microbiome has been linked to conditions ranging from immune disorders to mental health, yet conventional stool tests often fail to capture bacterial populations in the small intestine.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.