Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




1 Hour Direct-From-Blood Test Detects 95% Of Pathogens Associated with Bloodstream Infections

By LabMedica International staff writers
Posted on 11 Dec 2024

Early detection is crucial for treating a variety of infections, particularly sepsis. More...

Sepsis is responsible for one in three hospital deaths in the U.S., and septic shock has a global mortality rate of 30-40%. However, early diagnosis remains difficult due to the non-specific and often subtle symptoms. Currently, the standard method for diagnosing sepsis involves complex blood culture tests, which can take several days to provide results. This method, over 40 years old, is limited to identifying 'viable' organisms, often overlooking a wide array of microbial markers present in the blood. Now, a groundbreaking one-hour test can detect 95% of pathogens linked to bloodstream infections (BSIs) that could lead to sepsis, along with specific genetic markers for antimicrobial resistance (AMR).

deepull’s (Barcelona, Spain) UllCORE BSI Test and UllCore system offer 50 reportable results, identifying pathogens and antibiotic resistance markers directly from blood within about one hour. This real-time multiplex PCR system extracts microbial DNA from 8 mL of whole blood, bypassing the slow blood culture process. The assay covers a broad range of bacterial targets, fungi, and genetic determinants of antibiotic resistance. UllCORE’s rapid results and high sensitivity empower clinicians to make better-informed decisions, minimizing the risks of over- and under-treatment with antibiotics and contributing to efforts to combat antimicrobial resistance in hospitals. While focused on sepsis, deepull envisions its system as useful for diagnosing various other acute infections. The company has received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA) for the UllCORE BSI Test.

“We are thrilled to receive breakthrough designation from the FDA,” said Jordi Carrera, Chief Executive Officer and Co-Founder of deepull. “Providing life-saving results for patients suspected of serious infection in one hour represents a significant advantage over current standard of care blood culture. Faster pathogen identification and AMR testing will provide clinicians with a powerful tool to more quickly and accurately tailor antimicrobial therapy, which could lead to faster patient recovery, shorter length of stay, and reduced morbidity and mortality.”

Related Links:
deepull


Gold Member
Serological Pipets
INTEGRA Serological Pipets
Portable Electronic Pipette
Mini 96
New
Laboratory Software
ArtelWare
New
Gold Member
Cardiovascular Risk Test
Metabolic Syndrome Array I & II
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Molecular Diagnostics

view channel
Image: Left is the original cell image and right is same cell image zoomed in and rendered in the special imaging software (Photo courtesy of FIU)

Brain Inflammation Biomarker Detects Alzheimer’s Years Before Symptoms Appear

Alzheimer’s disease affects millions globally, but patients are often diagnosed only after memory loss and other symptoms appear, when brain damage is already extensive. Detecting the disease much earlier... Read more

Hematology

view channel
Image: New research points to protecting blood during radiation therapy (Photo courtesy of 123RF)

Pioneering Model Measures Radiation Exposure in Blood for Precise Cancer Treatments

Scientists have long focused on protecting organs near tumors during radiotherapy, but blood — a vital, circulating tissue — has largely been excluded from dose calculations. Each blood cell passing through... Read more

Immunology

view channel
Image: The VENTANA HER2 (4B5) test is now CE-IVDR approved (Photo courtesy of Roche)

Companion Diagnostic Test Identifies HER2-Ultralow Breast Cancer and Biliary Tract Cancer Patients

Breast cancer is the most common cancer in Europe, with more than 564,000 new cases and 145,000 deaths annually. Metastatic breast cancer is rising in younger populations and remains the leading cause... Read more

Pathology

view channel
Image: An adult fibrosarcoma case report has shown the importance of early diagnosis and targeted therapy (Photo courtesy of Sultana and Sailaja/Oncoscience)

Accurate Pathological Analysis Improves Treatment Outcomes for Adult Fibrosarcoma

Adult fibrosarcoma is a rare and highly aggressive malignancy that develops in connective tissue and often affects the limbs, trunk, or head and neck region. Diagnosis is complex because tumors can mimic... Read more

Technology

view channel
Image: Conceptual design of the CORAL capsule for microbial sampling in the small intestine (H. Mohammed et al., Device (2025). DOI: 10.1016/j.device.2025.100904)

Coral-Inspired Capsule Samples Hidden Bacteria from Small Intestine

The gut microbiome has been linked to conditions ranging from immune disorders to mental health, yet conventional stool tests often fail to capture bacterial populations in the small intestine.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.