We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Noninvasive Device Measures Hemoglobin More Accurately in Individuals with Darker Skin Pigmentations

By LabMedica International staff writers
Posted on 31 Oct 2022
Print article
Image: New tech aims to reduce racial disparities in blood measurements (Photo courtesy of University of Texas at Arlington)
Image: New tech aims to reduce racial disparities in blood measurements (Photo courtesy of University of Texas at Arlington)

Racial disparities in hemoglobin and blood oxygen measurements are an urgent public health issue. The devices presently in use are inaccurate in people with dark skin. Most methods for monitoring hemoglobin require blood samples and expensive equipment. Currently available pulse-oximeters use red-infrared light and are based on technology first designed more than 50 years ago. The available noninvasive spectroscopic methods have a high degree of variability and often are inaccurate in people of color due to differences in skin melanin. There is a significant unmet need for a reliable, noninvasive device to estimate hemoglobin, irrespective of skin color. Now, researchers have demonstrated a new device that measures hemoglobin more accurately in individuals with darker skin pigmentations by using the spectroscopic properties of hemoglobin in the blue-green light spectra.

In a clinical study, a team of researchers at the University of Texas at Arlington (Arlington, TX, USA) along with Shani Biotechnologies LLC (Austin, TX, USA) measured the hemoglobin and oxygen content of 16 healthy volunteers using the newly developed technology. The team compared the results to those obtained using a commercially available pulse-oximeter for accuracy and variability. The findings of the study are encouraging, and the new technology has massive potential to address this clinical unmet need. The researchers intend to develop a wearable device, such as a watch or a monitor, that would read the blood through the skin.

“We have used the green-blue light and have successfully tested the device in preclinical and clinical studies,” said Dr. Vinoop Daggubati of Shani Biotechnologies LLC. “Our group has addressed the issues around shorter wavelength, scattering of light and the impact of skin melanin. The scientific community should open its mind to the concept of green light for these measurements. The Shani device has huge potential to eliminate this racial disparity.”

Related Links:
University of Texas at Arlington 
Shani Biotechnologies 

Gold Supplier
POC Test Reader
Auto Liquid Handling & Homogenizer Workstation
LH 96
Serratia Marcescens Test
CHROMagar Serratia
Silver Supplier
Diagnostic Manufacturing

Print article


Clinical Chem.

view channel
Image: Equivalence of Genetically Elevated LDL and Lipoprotein(a) on Myocardial Infarction (Photo courtesy of Viborg Regional Hospital)

Familial Hypercholesterolemia Patients With ACD Have Elevated Lipoprotein(a)

Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein (LDL cholesterol), in the blood and early cardiovascular... Read more

Molecular Diagnostics

view channel
Image: A cheap blood test could improve diagnosis of myocarditis (Photo courtesy of Queen Mary University of London)

First-Ever Blood Test Could Detect Deadly Heart Inflammation Within Hours

Myocarditis, or inflammation of the heart muscle, is a difficult condition to diagnose. Symptoms include a temperature, fatigue, chest pain and shortness of breath, which can all be easily mistaken for... Read more


view channel
Image: Ring-form trophozoites of Plasmodium vivax in a thin blood smear (Photo courtesy of Centers for Disease Control and Prevention)

Immune Regulators Predict Severity of Plasmodium vivax Malaria

Cytokines and chemokines are immune response molecules that display diverse functions, such as inflammation and immune regulation. In Plasmodium vivax infections, the uncontrolled production of these molecules... Read more


view channel
Image: Breast cancer spread uncovered by new molecular microscopy (Photo courtesy of Wellcome Sanger Institute)

New Molecular Microscopy Tool Uncovers Breast Cancer Spread

Breast cancer commonly starts when cells start to grow uncontrollably, often due to mutations in the cells. Overtime the tumor becomes a patchwork of cells, called cancer clones, each with different mutations.... Read more


view channel
Image: With Cell IDx’s acquisition, Leica Biosystems will be moving its multiplexing menu forward (Photo courtesy of Leica Biosystems)

Leica Biosystems Acquires Cell IDx, Expanding Offerings in Multiplexed Tissue Profiling

Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging (Nussloch, Germany), has acquired Cell IDx, Inc. (San Diego, CA, USA), which provides multiplex staining... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.