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Clinical Chemistry

Image: The UniCel Dxl 800 Access 2 immunoassay system (Photo courtesy of Beckman Coulter).

Blood Biomarkers Help Diagnose Obstructive Sleep Apnea

The relationship between obstructive sleep apnea (OSA) and blood biomarkers has been assessed and the hypothesis tested that combinations of markers provide a characteristic OSA signature with diagnostic screening value. More...
26 Jun 2018
Image: The Elecsys high-sensitivity cardiac troponin T (hs-cTnT ) assay (Photo courtesy of Roche Diagnostics).

Cardiac Infarction Diagnosed with Sensitive Method

Chest pain is one of the most common reasons people seek emergency medical care. To determine if a person has suffered a cardiac infarction, symptoms are assessed partly on the basis of chest pain and partly with an electrocardiogram taken to detect typical changes consistent with a heart attack. More...
24 Jun 2018
Image: A radiograph of 50-year-old patient with a well-placed acetabular cup against the tear drop and well placed femoral stem; after seven years, the patient has developed extensive osteolysis (Photo courtesy of Duke University Medical Center).

Urinary Markers Predict Bone Problems after Hip Replacement

Osteolysis is an active resorption of bone matrix by osteoclasts and can be interpreted as the reverse of ossification. Although osteoclasts are active during the natural formation of healthy bone the term "osteolysis" specifically refers to a pathological process. More...
20 Jun 2018
Image: The FLOUstar optima plate reader (Photo courtesy of BMG Labtech).

Link Identified between Inflammation and Depression

It is well established that people with both type-1 and type-2 diabetes have an increased risk of developing depression, a debilitating mental health disorder with potentially serious consequences, but the causes remain poorly understood. More...
20 Jun 2018
Image: A blood test for Vitamin D, where deficiency may indicate higher plasma lipid levels (Photo courtesy of bluehorizon).

High Vitamin D Levels Linked to Lower Cholesterol

Vitamin D is known to be essential for bone metabolism, and low serum 25(OH)D levels increase the risk of rickets, osteomalacia, and osteopenia. The associations of serum 25-hydroxyvitamin D (25(OH)D) with plasma lipids remain controversial in children. More...
19 Jun 2018
Image: A blood test for vitamin D; insufficiency is linked to miscarriage among women with prior pregnancy loss (Photo courtesy of Blood Tests London).

Insufficient Vitamin D Linked to Miscarriage with Prior Loss

Vitamin D deficiency during pregnancy is associated with adverse pregnancy outcomes, although the association between preconception vitamin D concentrations and live birth is unknown. More...
14 Jun 2018
Image: Testosterone/estradiol ratio and the risk of cardiovascular disease, coronary heart disease and heart failure (HF) in post-menopausal women (Photo courtesy of Johns Hopkins Medicine).

Hormone Levels Alter CVD Risk in Older Women

Higher androgen and lower estrogen levels are associated with cardiovascular disease (CVD) risk factors in women; however, studies on sex hormones and incident CVD events in women have yielded conflicting results. More...
13 Jun 2018
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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