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Undiagnosed Thyroid Problems Discovered Through Computerized Screening

By LabMedica International staff writers
Posted on 07 Aug 2012
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Scientists in India have developed an improved expert system for the diagnosis of thyroid disease.

Jaganathan Palanichamy and Rajkumar Nallamuthu of the PSNA College of Engineering and Technology (Tamilnadu, India found that the classification of a raw dataset from patient records could allow undiagnosed thyroid problems to be discovered through computerized screening.

The screening algorithm developed by the PSNA team boosts the accuracy of earlier approaches, bringing the level to almost 93.5%, as opposed to earlier tests that had 92% confidence or less. That means that 15 more patients are given neither a false positive nor a false negative of every 1,000 in the screened database.

Over a healthcare network with millions of patients that can amount to significant numbers of people correctly identified with a thyroid problem based on patient records rather than having to carry out specific thyroid function blood tests. The screening approach could also be used by doctors in a clinical setting to assess patients that present with a range of symptoms and so identify with precision whether a thyroid test and subsequent pharmaceutical intervention is required.

Thyroid disease in which either too much thyroid hormone is produced or too little is made are common health problems. An overactive thyroid can lead to increased perspiration, a raised pulse, tremors, anxiety, nervousness and irritability, insomnia, thinning of the skin, fine brittle hair, and muscular weakness. A sluggish thyroid might cause constipation, cold intolerance, decreased sweating, a slow pulse, depression, dry skin, and poor female fertility. Thyroid disease is often asymptomatic and is frequently undiagnosed.

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PSNA College of Engineering and Technology



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