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BioResearch

Image: Bone regenerates when two human cell populations (pericytes and adventitial cells) are mixed and implanted in a skull bone defect in immunocompromised mice (Photo courtesy of Yiyun Wang, Johns Hopkins University).

Mixture of Adipose-derived Cells Prove Better at Inducing Bone Repair

Researchers have defined the differential but overlapping roles of two cell subsets involved in the paracrine induction of bone repair. More...
06 Mar 2019
Image: Yerba Santa growing on roadside in California, USA (Photo courtesy of Wikimedia Commons).

Sterubin Shown to Possess Neuroprotective and Anti-inflammatory Properties

Sterubin, a flavonoid isolated from extracts of a North American medicinal plant was found to have potent neuroprotective and anti-inflammatory properties. More...
05 Mar 2019
Image: A confocal microscope image shows the SA-4-1BBL (green color) bound to its receptor on an immune cell (red color) to initiate an immune activation cascade to fight cancer (Photo courtesy of the University of Louisville).

Engineered Ligand Protein Protects Mice from Developing Cancer

A team of cancer researchers has developed a recombinant protein molecule that, when injected into mice, was able to protect the animals against subsequent tumor challenge irrespective of the tumor type. More...
04 Mar 2019
Image: Structure of the C-terminal helical repeat domain of eukaryotic elongation factor 2 kinase (EEF2K) (Photo courtesy of the U.S. National Center for Biotechnology Information).

Inactivation of Enzyme Corrects Alzheimer's Disease Defects

A team of neurodegenerative disease researchers identified a molecular mechanism that impedes protein synthesis and may contribute to the loss of memory and synaptic plasticity that characterizes Alzheimer's disease (AD). More...
28 Feb 2019
Image: Platelet decoys (pink), unlike normal platelets, are not activated by collagen fibers (gray), making them an attractive option for antithrombotic and cancer treatment (Photo courtesy of Harvard University).

Modified Platelets Reduce Risk of Blood Clots and Prevent Metastasis

A promising method for reducing the risk of blood clots and preventing tumor metastasis is based on treatment with blood platelets that have been modified to be incapable of activation and aggregation while retaining their functional binding properties. More...
27 Feb 2019
Image: Researchers found that cells behave differently in this three-dimensional (3D) soft tissue environment than on two-dimensional (2D) plastic or glass surfaces (Photo courtesy of the University of Minnesota).

Bioprinting Studies How Cancer Cells Grow and Spread

Novel use of a three-dimensional (3D) bioprinting technique has created new ways to study how cancer cells grow and spread. More...
26 Feb 2019
Image: The new AggTag method allows researchers to see the previously undetectable but potentially disease-causing intermediate forms of proteins as they misfold. The method uses fluorescence to simultaneously detect two different proteins (red, green) within the cell (blue) (Photo courtesy of the Zhang Laboratory, Pennsylvania State University).

Fluorescence-Based Method Detects Misfolded Proteins in Cells

A new fluorescence-based method is expected to boost studies on toxic insoluble proteins by detecting aggregation of two proteins in live cells simultaneously. More...
25 Feb 2019
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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