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BioResearch

Image: A diagram of construction of a genomic library (Photo courtesy of Wikimedia Commons).

New Method Simplifies Preparation of Tumor Genomic DNA Libraries

A method has been described that simplifies preparation of tumor genomic DNA libraries by employing restriction enzymes and in vitro transcription to barcode and amplify genomic DNA prior to library construction. More...
28 Oct 2019
Image: Atopic dermatitis of the inside crease of the elbow (Photo courtesy of Wikimedia Commons).

Adhesive Tape Strips Offer an Alternative Biopsy Method for Diagnosis of Atopic Dermatitis

Results of a recent study supported the use of adhesive tape strips to obtain biopsy specimens for the diagnosis of atropic dematitis (eczema). More...
23 Oct 2019
Image: Diagram workflow for co-amplification at lower denaturation temperature PCR (COLD-PCR)/fluorescence melting curve analysis (FMCA) (Photo courtesy of The First Affiliated Hospital of Fujian Medical University).

New Tool Developed for Diagnosis of Chronic HBV Infection

A team of Chinese researchers has described the development of a new and powerful tool for the diagnosis and treatment of chronic hepatitis B virus (HBV) infection. More...
23 Oct 2019
Image: Spiked rods of monosodium urate crystals photographed under polarized light from a synovial fluid sample. Formation of monosodium urate crystals in the joints is associated with gout (Photo courtesy of Wikimedia Commons).

Panel of Genetic Loci Accurately Predicts Risk of Developing Gout

A large GWAS (genome-wide association study) highlighted genetic loci associated with the metabolic regulation of serum levels of uric acid (urate) and identified a panel of 183 loci linked to the risk of developing gout. More...
14 Oct 2019
Image: A representation of CEACAM5 protein (Photo courtesy of Wikimedia Commons).

Disrupted TGFB Signaling Linked to Increased Cancer-Related Bacteria

Following careful analysis of DNA sequences collected in The Cancer Genome Atlas, researchers have proposed that CEACAM (carcinoembryonic antigen related cell adhesion molecule) proteins disrupt TGFB signaling, which alters the composition of the intestinal microbiome to promote development of colorectal cancer. More...
14 Oct 2019
Image: Human Kallikrein 4 (KLK4) protein complexed with nickel and p-aminobenzamidine  (Photo courtesy of Wikimedia Commons).

Gene Fusion Protein Proposed as Prostate Cancer Biomarker

A novel gene fusion product has been proposed as a biomarker for the non-invasive diagnosis of prostate cancer. More...
14 Oct 2019
Image: A ball-and-stick model of the 5-hydroxymethylcytosine (5hmC) molecule (Photo courtesy of Wikimedia Commons).

NIV Test to Diagnose and Monitor Vascular Complications in Diabetes

By applying a sensitive test for analysis of DNA taken from patients with Type II diabetes, researchers were able to diagnose and monitor the presence and severity of diabetic vascular complications such as heart disease, atherosclerosis, and kidney failure. More...
07 Oct 2019
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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