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Image: A simplified diagram of the structure of Epstein-Barr virus (EBV) (Photo courtesy of Wikimedia Commons).

New Anticancer Drugs Interfere with DNA Binding Properties of EBV

The recent synthesis of small molecular drugs that interfere with the DNA binding properties of Epstein-Barr virus (EBV) suggests that it may be possible to develop medications for the treatment of EBV-associated cancers. More...
18 Mar 2019
Image: Specialized proteins protect damaged DNA in the cell nucleus (pink shapes) until the damage can be repaired (Photo courtesy of the University of Copenhagen).

Specialized Nuclear Bodies Delay and Promote Repair of DNA Damage

A molecular mechanism that helps minimize the impact of natural DNA errors, which occur during the process of cell division and replication, was identified and characterized in cultures of human cells. More...
14 Mar 2019
Image: Fruit flies (Drosophila) with mutated antimicrobial peptides (red eyes) let bacteria (green fluorescence) grow out of control, while wild-type flies (with normal antimicrobial peptides) suppress the infection (Photo courtesy of Dr. Mark Austin Hanson, École Polytechnique Fédérale de Lausanne).

Gene Editing Reveals Interaction between Antimicrobial Peptides and Pathogens

The genome editing tool CRISPR/Cas9 was used to delete the genes coding for inducible antimicrobial peptides (AMPs) in fruit flies (Drosophila), which revealed the highly specific interaction between AMPs and pathogens in an in vivo model system. More...
13 Mar 2019
Image: Cellular barcoding may help to better understand how breast cancer evolves and how treatment strategies can be refined for increased benefits (Photo courtesy of Breast Cancer News).

Cellular Barcoding Used to Characterize Clones of Breast Tumor Cells

Cancer researchers used an advanced cellular barcoding technique to characterize cells in primary and disseminated tumors in mouse models of human triple-negative breast cancer. More...
12 Mar 2019
Image: The structure of the third complement (C3) protein (Photo courtesy of Wikipedia).

Natural Antibodies Can Prevent Adverse Immune Reactions

Natural antibodies, in particular IgG, have been shown to be a critical factor that determines the efficiency of complement activation in different subjects and by different nanomaterials. More...
11 Mar 2019

Diet Supplemented with Blueberry Anthocyanins Reduces CVD Risk

Consumption of a diet supplemented with anthocyanins purified from blueberries for one month was shown to improve blood vessel function and decrease systolic blood pressure in a group of healthy volunteers. More...
07 Mar 2019
Image: Bone regenerates when two human cell populations (pericytes and adventitial cells) are mixed and implanted in a skull bone defect in immunocompromised mice (Photo courtesy of Yiyun Wang, Johns Hopkins University).

Mixture of Adipose-derived Cells Prove Better at Inducing Bone Repair

Researchers have defined the differential but overlapping roles of two cell subsets involved in the paracrine induction of bone repair. More...
06 Mar 2019
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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