We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App

Rapid POC Diagnostic Assay Could Detect and Measure Fentanyl Neutralizing Antibodies

By LabMedica International staff writers
Posted on 23 Jan 2023
Print article
Image: The new test is designed to measure neutralizing antibodies of the deadly opioid fentanyl (Photo courtesy of AXIM)
Image: The new test is designed to measure neutralizing antibodies of the deadly opioid fentanyl (Photo courtesy of AXIM)

Fentanyl is a powerful synthetic opioid with a strong addiction profile that is 50 to 100 times stronger than morphine and is the world’s leading cause of overdose. The current healthcare landscape makes it difficult to prevent fentanyl addiction and overdose. Researchers continue to conduct new studies on potential immunotherapies and vaccines that can prevent fentanyl from crossing the blood-brain barrier to preemptively circumvent its overdose effects. Recent studies indicate that fentanyl neutralizing antibodies could prevent overdose deaths, although scientists will need to quantitatively measure a patient’s neutralizing antibodies throughout clinical studies and for relapse prevention from boosters. Such a test currently does not exist on the market.

AXIM Biotechnologies, Inc. (San Diego, CA, USA) is leveraging its experience in diagnostics and working with neutralizing antibodies to develop a rapid point-of-care diagnostic assay that will detect and measure the levels of fentanyl neutralizing antibodies. The breakthrough diagnostic solution will allow therapeutic and vaccine scientists to bring their research from the lab to the clinic more quickly, thanks to the fast time to result in clinical settings provided by AXIM’s new test. The US and other government and regulatory bodies are incentivizing organizations through grants and licenses to conduct research on potential therapeutics or vaccines that can prevent fentanyl overdose or addiction. AXIM will market its newly-developed test to these research institutions as a reliable way to measure neutralizing antibodies in clinical trial patients.

AXIM has filed a provisional patent application with the U.S. Patent and Trademark Office on its innovative new test. Additionally, the company has filed for a license to handle the controlled substance with the Drug Enforcement Administration (DEA) as required for research. AXIM’s ongoing discussions with various academic and research groups on potential collaboration on the new test has generated broad enthusiasm among the scientific community for its development and commercialization.

“This test is another example of the broad applications of AXIM’s diagnostic platform,” said John Huemoeller II, CEO of AXIM Biotechnologies. “We continue to be able to leverage our processes and scientific expertise in developing rapid diagnostic assays of commercial significance. As most know, the fentanyl crisis continues to plague the US as well as many other countries and scientists from a myriad of fields continue to research ways to combat the devastation this lethal drug is causing. The commercial applications of this test are far and wide and represent a massive opportunity for AXIM. Once we receive our DEA license, we plan to begin clinical studies on the assay immediately, with the hopes of commercialization in the second quarter of 2023.”

Related Links:
AXIM Biotechnologies, Inc.

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Magnetic Bead Separation Modules
Complement 3 (C3) Test
GPP-100 C3 Kit
Gold Member
Magnetic Bead Separation Modules

Print article


Clinical Chemistry

view channel
Image: The 3D printed miniature ionizer is a key component of a mass spectrometer (Photo courtesy of MIT)

3D Printed Point-Of-Care Mass Spectrometer Outperforms State-Of-The-Art Models

Mass spectrometry is a precise technique for identifying the chemical components of a sample and has significant potential for monitoring chronic illness health states, such as measuring hormone levels... Read more


view channel
Image: The CAPILLARYS 3 DBS devices have received U.S. FDA 510(k) clearance (Photo courtesy of Sebia)

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Hemoglobinopathies, the most widespread inherited conditions globally, affect about 7% of the population as carriers, with 2.7% of newborns being born with these conditions. The spectrum of clinical manifestations... Read more


view channel
Image: A false color scanning election micrograph of lung cancer cells grown in culture (Photo courtesy of Anne Weston)

AI Tool Precisely Matches Cancer Drugs to Patients Using Information from Each Tumor Cell

Current strategies for matching cancer patients with specific treatments often depend on bulk sequencing of tumor DNA and RNA, which provides an average profile from all cells within a tumor sample.... Read more


view channel
Image: Microscope image showing human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color (Photo courtesy of Fred Hutch Cancer Center)

Mouth Bacteria Test Could Predict Colon Cancer Progression

Colon cancer, a relatively common but challenging disease to diagnose, requires confirmation through a colonoscopy or surgery. Recently, there has been a worrying increase in colon cancer rates among younger... Read more


view channel
Image: Fingertip blood sample collection on the Babson Handwarmer (Photo courtesy of Babson Diagnostics)

Unique Hand-Warming Technology Supports High-Quality Fingertip Blood Sample Collection

Warming the hand is an effective way to facilitate blood collection from a fingertip, yet off-the-shelf solutions often do not fulfill laboratory requirements. Now, a unique hand-warming technology has... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.