We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




Prototype Microspectrometer Suitable for Lab-on-a-Chip Technologies

By LabMedica International staff writers
Posted on 12 Aug 2013
By passing a beam of light through a silicon chip pierced with randomly scattered holes investigators have developed a sensitive microspectrometer that may be adaptable for "lab-on-a-chip" applications.

Investigators at Yale University (New Haven, CT, USA) reported in the July 28, 3013, online edition of the journal Nature Photonics that they had built a spectrometer based on multiple light scattering in a silicon-on-insulator chip featuring a random structure. More...
A probe signal diffused through the chip generating wavelength-dependent speckle patterns, which were detected and used to recover the input spectrum after calibration. A spectral resolution of 0.75 nanometers at a wavelength of 1,500 nanometers in a 25-micrometer-radius structure was achieved.

“The largest dimension of our spectrometer, which we built on a silicon chip, is about the width of a human hair,” said first author Dr. Brandon Redding, a postdoctoral associate in applied physics at Yale University. “It could open up a whole new range of uses, a lot of them outside the lab.”

The microspectrometer can detect a change in wavelength of less than one nanometer, roughly matching the capability of macroscopic spectrometers about the size of a hard drive. “We were taking a very different approach,” said Dr. Redding. “The idea of using disorder and multiple scattering is a fairly unexplored concept. Normally, disorder is something you want to overcome or avoid. In this case, it is what lets us make the device so small. We get a much longer path length for our light relative to the size of the device, because the light bounces around many times.”

The authors maintain that a compact, high-resolution spectrometer, such as that described in this study, is well suited for lab-on-a-chip spectroscopy applications.

Related Links:

Yale University




Gold Member
Quality Control Material
iPLEX Pro Exome QC Panel
Online QC Software
Acusera 24•7
Automated Urinalysis Solution
UN-9000
Multi-Chamber Washer-Disinfector
WD 390
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Clinical Chemistry

view channel
Image: Characterization of EV separated by distinct methods (Photo courtesy of Yuanyuan Liu, Yanbin Guo et al. Engineering, doi.org/10.1016/j.eng.2025.12.009)

Liquid Biopsy Biomarkers May Improve Childhood Epilepsy Diagnosis

Childhood epilepsy remains a major neurological disorder with unmet needs for accurate, non-invasive biomarkers, as conventional tests such as electroencephalography and neuroimaging can have limited sensitivity... Read more

Molecular Diagnostics

view channel
Image: NeoCircle Study Synopsis (George, A.M., Chen, Y., Gladchuk, S. et al. EMBO Molecular Medicine (2026). DOI: 10.1038/s44321-026-00447-z)

Ultrasensitive MRD Blood Test Detects Early Breast Cancer Recurrence

SAGA Diagnostics (Morrisville, NC, USA), a company specializing in tumor-informed, blood-based cancer detection and precision medicine, announced the publication of a new study evaluating its Pathlight... Read more

Pathology

view channel
Image: Immune-related signals in routine bone marrow biopsy slides could help predict multiple myeloma outcomes and support more personalized treatment strategies (image credit: Shutterstock)

AI Tool Extracts Immune Signals from Biopsy to Inform Myeloma Therapy

Multiple myeloma is a bone marrow malignancy in which patients can respond very differently to the same treatments, making initial therapy decisions difficult. Clinicians must choose among options such... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.