We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




Prototype Microspectrometer Suitable for Lab-on-a-Chip Technologies

By LabMedica International staff writers
Posted on 12 Aug 2013
By passing a beam of light through a silicon chip pierced with randomly scattered holes investigators have developed a sensitive microspectrometer that may be adaptable for "lab-on-a-chip" applications.

Investigators at Yale University (New Haven, CT, USA) reported in the July 28, 3013, online edition of the journal Nature Photonics that they had built a spectrometer based on multiple light scattering in a silicon-on-insulator chip featuring a random structure. More...
A probe signal diffused through the chip generating wavelength-dependent speckle patterns, which were detected and used to recover the input spectrum after calibration. A spectral resolution of 0.75 nanometers at a wavelength of 1,500 nanometers in a 25-micrometer-radius structure was achieved.

“The largest dimension of our spectrometer, which we built on a silicon chip, is about the width of a human hair,” said first author Dr. Brandon Redding, a postdoctoral associate in applied physics at Yale University. “It could open up a whole new range of uses, a lot of them outside the lab.”

The microspectrometer can detect a change in wavelength of less than one nanometer, roughly matching the capability of macroscopic spectrometers about the size of a hard drive. “We were taking a very different approach,” said Dr. Redding. “The idea of using disorder and multiple scattering is a fairly unexplored concept. Normally, disorder is something you want to overcome or avoid. In this case, it is what lets us make the device so small. We get a much longer path length for our light relative to the size of the device, because the light bounces around many times.”

The authors maintain that a compact, high-resolution spectrometer, such as that described in this study, is well suited for lab-on-a-chip spectroscopy applications.

Related Links:

Yale University




New
Gold Member
Collection and Transport System
PurSafe Plus®
Portable Electronic Pipette
Mini 96
New
Automated MALDI-TOF MS System
EXS 3000
Autoimmune Disease Diagnostic
Chorus ds-DNA-G
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Molecular Diagnostics

view channel
Image: The Ultrasensitive NeXT Personal Test detects the earliest molecular signs of recurrence in breast cancer patients (Photo courtesy of Personalis)

Ultrasensitive Test Could Identify Earliest Molecular Signs of Metastatic Relapse in Breast Cancer Patients

HR+ (hormone receptor-positive) HER2- (human epidermal growth factor receptor 2-negative) breast cancer represents over 70% of all breast cancer cases and carries a significant risk of late recurrence.... Read more

Hematology

view channel
Image: New research points to protecting blood during radiation therapy (Photo courtesy of 123RF)

Pioneering Model Measures Radiation Exposure in Blood for Precise Cancer Treatments

Scientists have long focused on protecting organs near tumors during radiotherapy, but blood — a vital, circulating tissue — has largely been excluded from dose calculations. Each blood cell passing through... Read more

Pathology

view channel
Image: An adult fibrosarcoma case report has shown the importance of early diagnosis and targeted therapy (Photo courtesy of Sultana and Sailaja/Oncoscience)

Accurate Pathological Analysis Improves Treatment Outcomes for Adult Fibrosarcoma

Adult fibrosarcoma is a rare and highly aggressive malignancy that develops in connective tissue and often affects the limbs, trunk, or head and neck region. Diagnosis is complex because tumors can mimic... Read more

Technology

view channel
Image: Conceptual design of the CORAL capsule for microbial sampling in the small intestine (H. Mohammed et al., Device (2025). DOI: 10.1016/j.device.2025.100904)

Coral-Inspired Capsule Samples Hidden Bacteria from Small Intestine

The gut microbiome has been linked to conditions ranging from immune disorders to mental health, yet conventional stool tests often fail to capture bacterial populations in the small intestine.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.