We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




Pioneering Saliva-Based Multiomic Platform to Transform Early Oral Cancer Detection

By LabMedica International staff writers
Posted on 17 Jun 2025

Head and neck cancers are the sixth most common. More...

Yet, over 60% of cases are detected late, with late-stage oral cancer detection surging by more than 1.5X in the last two decades. The current standard of care for oral cancer involves visual inspection, which often leads to only 20% of cases being successfully identified, resulting in hundreds of thousands of unnecessary surgical biopsies. Now, a breakthrough technology is harnessing the power of salivary diagnostics to transform early detection and prevention of oral cancer.

OrisDX (Chicago, IL, USA) has developed a multiomic salivary diagnostic platform that uses non-invasive saliva samples and next-generation sequencing combined with proprietary algorithms to rapidly and accurately detect genetic biomarkers, setting a new standard in precision diagnostics. The company is now preparing for the commercial launch of its saliva-based multiomic platform, with its first indication for early oral cancer detection. Existing tests are based on indirect tools to detect oral cancer, either as light-based, brush tests, or singular biomarker solutions. The OrisDX test is a simple, non-invasive oral rinse that delivers 93% sensitivity and 99% specificity. This groundbreaking accuracy significantly outperforms the current standard of care for oral cancer.

Built on proprietary molecular technology, it enables earlier, more accurate diagnosis and replaces the uncertainty of visual inspection and invasive biopsies. In addition to screening patients at high risk of developing cancer, the tool enables physicians to assess patient response to treatment in real-time and adjust the course as needed. Head and neck cancers are known for high recurrence, especially during the first two years after treatment, so it is important to continue with regular testing, which the OrisDX test makes easier. The commercial rollout of OrisDX’s diagnostic platform will be across dental, oncology, and medical channels.

“OrisDX was built upon the first generation of blood-based liquid biopsy pioneers with an intense focus on the multiomics of the next frontier, salivaomics,” said Harald Steltzer, CEO of OrisDX. “The easy, pain-free collection of saliva offers the broadest opportunity for patients to provide samples at the convenience of a clinic or home.”

Related Links:
OrisDX


New
Gold Member
Quality Control Material
iPLEX Pro Exome QC Panel
3-Part Differential Hematology Analyzer
Swelab Alfa Plus Sampler
New
ESR Analyzer
TEST1 2.0
New
Sample Transportation System
Tempus1800 Necto
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








DIASOURCE (A Biovendor Company)

Channels

Hematology

view channel
Image: The microfluidic device for passive separation of platelet-rich plasma from whole blood (Photo courtesy of University of the Basque Country)

Portable and Disposable Device Obtains Platelet-Rich Plasma Without Complex Equipment

Platelet-rich plasma (PRP) plays a crucial role in regenerative medicine due to its ability to accelerate healing and repair tissue. However, obtaining PRP traditionally requires expensive centrifugation... Read more

Immunology

view channel
Image: The 3D paper-based analytical device has shown high clinical accuracy for adult-onset immunodeficiency (Photo courtesy of National Taiwan University)

Paper-Based Device Accurately Detects Immune Defects in 10 Minutes

Patients with hidden immune defects are especially vulnerable to severe and persistent infections, often due to autoantibodies that block interferon-gamma (IFN-γ), a key molecule in immune defense.... Read more

Pathology

view channel
Image: Researchers have developed a novel method to analyze tumor growth rates (Photo courtesy of Adobe Stock)

Novel Method To Analyze Tumor Growth Rates Helps Tracks Progression Between Diagnosis and Surgery

Patients diagnosed with breast cancer often worry about how quickly their tumors grow while they wait for surgery, and whether delays in treatment might allow the disease to spread beyond the point of cure.... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.