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Hematology

Model of the HbA1c molecule (image courtesy of Biologic Models)

Elevated Glycolated Hemoglobin in Young People Predicts Likelihood of Diabetes or Cardiovascular Disease in Adulthood

A review of blood test results from more than 14,000 young people suggested that measurement of glycated hemoglobin (HbA1c) was a specific and useful nonfasting marker for identify high-risk youth who could benefit from lifestyle interventions to prevent diabetes and cardiovascular risk in adulthood. More...
19 Aug 2020
By measuring glycated hemoglobin (HbA1c), clinicians are able to get an overall picture of what the average blood sugar levels have been over a period of weeks/months (Photo courtesy of Diabetes.co.uk).

High Blood Glucose Tied to Cardiovascular Risk in Diabetes

 Glycated hemoglobin (HbA1c) is a measure of an overall picture of what the average blood sugar levels have been over a period of weeks/months. If the blood sugar levels have been high over recent weeks, the hemoglobinA1c test will be higher. More...
14 Aug 2020
The QuantiFERON‐TB Gold Plus IFN‐γ release assay used to help diagnose hemophagocytic lymphohistiocytosis (Photo courtesy of Qiagen).

IFN‐γ Release Assay Helps Diagnose Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH), either primary (pHLH, or Familiar, FHL) or secondary is a life‐threatening hyper‐inflammatory syndrome, characterized by massive and uncontrolled activation of macrophages and T cells, causing fever, cytopenia and liver dysfunction with coagulopathy. More...
14 Aug 2020
Ring-form trophozoites of Plasmodium falciparum and a white blood cell in a thick blood film (Photo courtesy of Medical Care Development International).

Automated Malaria Diagnosis Enhanced by Deep Neural Networks

Plasmodium falciparum malaria remains one of the greatest global health burdens with over 228 million cases globally in 2018. In that year there were approximately 405,000 deaths due to malaria worldwide, with the African region accounting for 93% of these deaths, mostly among children. More...
14 Aug 2020
Image: The Multisizer 4e Coulter Counter is a highly versatile particle counting and characterization system (Photo courtesy of Beckman Coulter).

Eosinophil Count Provides Diagnostic Information for COVID-19

Early diagnosis of coronavirus disease 2019 (COVID-19) and patient isolation are important for both individual patient care and disease containment. The diagnosis is confirmed by testing for the presence of nasopharyngeal viral RNA with a polymerase chain reaction assay, which has limited availability, variable turnaround time, and a high false-negative rate. More...
29 Jul 2020
Image: Schematic diagram of the fully-automatic blood-typing chip exploiting bubbles for quick dilution and detection (Photo courtesy of Tokyo University of Science).

Micro-Lab on a Chip Detects Blood Type Within Minutes

Blood transfusion, if performed promptly, is a potentially life-saving intervention for someone losing a lot of blood. However, blood comes in several types, some of which are incompatible with others. Transfusing an incompatible blood type can severely harm a patient. More...
27 Jul 2020
Image: An ACL TOP Hemostasis Testing System (Photo courtesy of Instrumentation Laboratory).

Endotheliopathy Assessed in COVID-19-Associated Coagulopathy

An important feature of severe acute respiratory syndrome coronavirus 2 pathogenesis is COVID-19-associated coagulopathy, characterized by increased thrombotic and microvascular complications. COVID-19 infection coagulopathy is characterized by high D-dimer and fibrinogen concentrations with minor changes in prothrombin time and platelet count. More...
23 Jul 2020
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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