We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
RANDOX LABORATORIES

Download Mobile App





Sysmex and Kobe University Conduct Clinical Evaluation of New ELISPOT Method to Test for COVID-19 Using Blood

By LabMedica International staff writers
Posted on 29 Dec 2020
Print article
Illustration
Illustration
Sysmex Corporation (Kobe, Japan) and Kobe University (Kobe, Japan) are conducting joint research on the ELISPOT method, a new blood test for identifying COVID-19 that makes it possible to detect the immune response of T cells to the SARS-CoV-2 virus.

Although SARS-CoV-2 is highly infectious and may rapidly develop into a severe condition, many carriers of the virus are asymptomatic. To address this situation, research has been carried out to develop ways in which vaccine efficacy and safety can be assessed, in addition to the tests conducted in the period shortly after SARS-CoV-2 infection through to the treatment / recovery phase. T-SPOT Discovery SARS-CoV-2, the research reagent kit developed by Oxford Immunotec Ltd. (Oxford, UK), measures the number of T cells that secrete interferon (IFN) -γ by stimulating an infected SARS-CoV-2 specific antigen and can confirm past exposure to SARS-CoV-2 and latent infection. It will also enable research on immune monitoring and the strength of the immune response to COVID-19.

The research group from Kobe University Hospital BioResource Center and Sysmex used this kit to examine blood samples collected from 10 uninfected Japanese subjects and 15 Japanese subjects who had recovered from COVID-19. The results obtained so far show enhanced T cell immune responses in all individuals who recovered from COVID-19, while no enhanced T cell immune responses were found in uninfected individuals. This result suggests that the kit can be used to evaluate T cell immune response to SARS-CoV-2 in the Japanese population as well. It could also be utilized to complement PCR tests to measure gene expression, and antibody / antigen tests to measure the characteristics of proteins.

This kit has been selected by the Vaccines Taskforce established by the British government1 and is used to evaluate vaccines' activation of immune functions. It may also provide important findings that will aid the development of future treatment strategies. Sysmex and Kobe University will conduct further joint research at the molecular and cellular levels. Both parties will continue to contribute towards the diagnosis and treatment of COVID-19 by disclosing further details regarding T cell immunity and expeditiously establishing a test method suitable for clinical use.

Related Links:
Sysmex Corporation
Kobe University
Oxford Immunotec Ltd.


New
Gold Supplier
COVID-19 Test
iAMP COVID-19 Detection Kit
New
SARS-CoV-2 Antibody Test
Access SARS-CoV-2 IgG II Assay
New
COVID-19 Test
ID NOW COVID-19
SARS-COV-2 IgM/IgG Rapid Qualitative Test
GLINE-2019-nCoV IgM/IgG Rapid Qualitative Test

Print article

Channels

Molecular Diagnostics

view channel
Image: Histopathology of neurofibrillary tangles in the brain of a patient with Alzheimer`s disease (Bielschowski silver stain) (Photo courtesy of Dimitri P. Agamanolis, MD).

Alzheimer's Disease Subtypes Proposed from Brain Gene Expression Profiles

Alzheimer’s disease (AD) is the most common form of dementia in the elderly, estimated to affect more than 5.8 million individuals in the USA and more than 50 million worldwide, with almost half of individuals... Read more

Industry

view channel
Illustration

Thermo Fisher Acquires Point-of-Care Molecular Diagnostics Provider Mesa Biotech

Thermo Fisher Scientific Inc. (Waltham, MA, USA) has entered into a definitive agreement to acquire Mesa Biotech (San Diego, CA, USA), a privately held molecular diagnostic company, for approximately USD... Read more
Copyright © 2000-2021 Globetech Media. All rights reserved.