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Clinical Chemistry

Image: Study results show blood protein levels change markedly in childhood and adolescence, with sex differences increasing with age (photo credit: Adobe Stock)

Proteomic Data Underscore Need for Age-Specific Pediatric Reference Ranges

New data show pediatric serum proteins shift with age and sex, supporting more specific reference intervals. More...
25 Apr 2026
Image: An elevated neutrophil-to-lymphocyte ratio (NLR), a rato easily obtained from a routine blood count, was associated with both short- and long-term Alzheimer’s risk (photo credit: 123RF)

Routine Blood Count Ratio Linked to Future Alzheimer’s and Dementia Risk

New data link elevated neutrophil-to-lymphocyte ratio on CBC to higher future Alzheimer’s and dementia risk. More...
24 Apr 2026
Image: Schematic illustration of high-throughput, continuous-flow, and multi-scale enrichment of viable MTCs and MTCCs from pleural effusion samples using cascaded inertial microfluidics (Zhu, Z., Ren, H., Zhang, Z. et al. Microsyst Nanoeng 12, 101 (2026). doi.org/10.1038/s41378-026-01235-y)

Label-Free Microfluidic Device Enriches Tumor Cells and Clusters from Pleural Effusions

A new label-free microfluidic system enriches single and clustered malignant cells from pleural effusions, improving assessment. More...
24 Apr 2026
Image: The device contains specific antibodies that capture the primary biomarker of pancreatic cancer. The binding of these antibodies alters the distribution of electrical charges on the electrode surface. The sensor then translates this variation into a measurable capacitance signal (photo courtesy of Gabriella Soares / IFSC-USP)

Rapid Biosensor Detects Pancreatic Cancer Biomarker for Early Detection

An electrochemical biosensor detects CA19-9 in blood, enabling rapid, low-level testing for earlier pancreatic cancer detection. More...
24 Apr 2026
Photo courtesy of Adobe Stock

Urine-Based Multi-Cancer Screening Test Receives FDA Breakthrough Device Designation

A new urine-based MCED gains FDA Breakthrough to enable early detection of more than 10 cancers from a single sample. More...
21 Apr 2026
Image: Plasma pTau217 testing can predict future amyloid accumulation and cognitive decline in cognitively healthy older adults (photo courtesy of Shutterstock)

Blood Test Predicts Alzheimer Disease Risk Before Imaging Changes and Symptoms

Plasma pTau217 testing predicts future amyloid buildup and cognitive decline before PET, enabling early risk stratification. More...
15 Apr 2026
Image: ApoB is a blood test that counts the total number of harmful particles in circulation, providing a more complete assessment of risk (photo courtesy of Adobe Stock)

Study Finds ApoB Testing More Effective Than LDL for Guiding Lipid Therapy

New findings show apolipoprotein B (ApoB) testing better guides lipid therapy than LDL/non-HDL. More...
14 Apr 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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