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Novel AI-Driven Cardiac Blood Test Provides Highly Accurate Prediction of One-Year Risk for Heart Attack, Stroke, or Cardiac Death

A novel, artificial intelligence (AI)-driven blood test for cardiac risk can provide highly accurate prediction of one-year risk for heart attack, stroke, or cardiac death. More...
08 Aug 2021
Image: The images under fluorescence microscopy and light microscopy with four methods. A-D, show Candida albicans, and E-H, show C. glabrata; both the fungal color and the structure in FB 85 and CFW were clear and easily recognized from the background squamous cells compared with the KOH method (Photo courtesy of Capital Medical University)

Fluorescent Reagents Evaluated for Vulvovaginal Candidiasis Diagnosis

Vulvovaginal candidiasis (VVC) is a common vaginitis in females, which is estimated to be the second most common cause of vaginitis after bacterial vaginosis. Vulvovaginal candidiasis affects around 70%–75% of all women during their childbearing age, and is considered to be an important public health problem. More...
29 Jul 2021
Image: Nanoanalysis of plasma volatile organic compounds used novel DNA-decorated carbon nanotube vapor sensors to noninvasively distinguish ovarian and pancreatic cancer from benign and control samples (Photo courtesy of the University of Pennsylvania)

Electronic Nose Sensor Accurately Detects Ovarian, Pancreatic Cancers

Ovarian cancer is a cancer that forms in or on an ovary. It results in abnormal cells that have the ability to invade or spread to other parts of the body. When this process begins, there may be no or only vague symptoms. Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. More...
15 Jul 2021
Image: (c) Illustration of workflow for human buccal swab sample testing on the toroidal PCR. Total turnaround time is under one hour. (d) Genotyping 15 SNP loci from buccal swab samples from a family trio (Photo courtesy of Rice University)

Portable, PCR-Based Assay Developed for Rapid, Multiplexed DNA Detection

The detection of specific DNA sequences is central to precision medicine, from pathogen identification to the risk assessment of human genetic diseases to disease prognosis. While technologies exist for DNA detection, they tend to be limited either in terms of multiplexing, turnaround times, quantification accuracy, or specificity for single-nucleotide differences. More...
13 Jul 2021
Image: Artist’s depiction of stress molecules in blood being detected electronically inside nanowells (Photo courtesy of Ella Marushchenko)

A Novel Nanowell Array Sensor for POC Measurement of Stress Hormones

Researchers have constructed a microchip "nanosensor" to measure stress hormones such as cortisol in a dedicated nanowell array, which does not require molecular labels or washing steps. More...
13 Jul 2021
Image: Integrating programmable DNAzymes with electrical readout for rapid and culture-free bacterial detection using a handheld platform (Photo courtesy of McMaster University)

New Technology Can Diagnose Infections in Minutes

The detection and identification of bacteria currently rely on enrichment steps such as bacterial culture and nucleic acid amplification to increase the concentration of target analytes. These steps increase assay time, cost and complexity, making it difficult to realize a truly rapid point-of-care test. More...
08 Jul 2021
Image: The Celltac G fully-automatic hematology analyzer with 33 parameters (Photo courtesy of Nihon Kohden)

Leukocyte Differential on Hematology Analyzer Compared and Evaluated

A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells). More...
21 Jun 2021
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