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Image: These APOE gene alleles produce slightly different forms of the protein Apolipoprotein E (Photo courtesy of Genaro Gabriel Ortiz, MD, PhD, et al).

Alzheimer Disease Stratified by APOE Genotype

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and gradually worsens over time. It is the cause of 60% to 70% of cases of dementia. More...
27 Jun 2019
Image: A color hereditary cancer risk screening kit (Photo courtesy of Color Genomics).

Pathogenic Variant Carriers Missed by Current Genetic Testing

Current guidelines recommend genetic testing for people who have a personal or family history of cancer that indicates they might be at an increased risk of harboring a pathogenic familial variant, but this approach could miss people who lack any personal or family history. More...
27 Jun 2019
Image: A color hereditary cancer risk screening kit (Photo courtesy of Color Genomics).

Pathogenic Variant Carriers Missed by Current Genetic Testing

Current guidelines recommend genetic testing for people who have a personal or family history of cancer that indicates they might be at an increased risk of harboring a pathogenic familial variant, but this approach could miss people who lack any personal or family history. More...
27 Jun 2019
Image: Blue-stained dots are Chikungunya virus particles peppering the surface of an infected cell (Photo courtesy of Institute Pasteur/Thérèse Couderc).

RT-LAMP Used to Genotype and Diagnose Chikungunya

Chikungunya virus has re-emerged as an important pathogen causing several outbreaks in the world. As the clinical symptoms of chikungunya are similar to other mosquito-borne febrile diseases, the definitive diagnosis of the disease is based on the detection of viral genome from the patient blood. More...
27 Jun 2019
Image: Blue-stained dots are Chikungunya virus particles peppering the surface of an infected cell (Photo courtesy of Institute Pasteur/Thérèse Couderc).

RT-LAMP Used to Genotype and Diagnose Chikungunya

Chikungunya virus has re-emerged as an important pathogen causing several outbreaks in the world. As the clinical symptoms of chikungunya are similar to other mosquito-borne febrile diseases, the definitive diagnosis of the disease is based on the detection of viral genome from the patient blood. More...
27 Jun 2019
Image: The factor VIII:C/VWF:Ag ratio as a useful tool to predict relapse in patients with acquired hemophilia A (Photo courtesy of Joana Fernandes, PhD).

Potential Biomarker Identified for Relapse of Acquired Hemophilia A

Acquired hemophilia A (AHA) is a rare autoimmune bleeding disorder caused by the presence of autoantibodies against coagulation factor VIII (FVIII) and the mortality rate remains high. The disorder characterized by bleeding that occurs in patients with a personal and family history negative for hemorrhages. More...
26 Jun 2019
Image: A scanning electron photomicrograph of Candida albicans yeast cells (Photo courtesy of Science Photo Library).

Immune-Related Gene Implicated in Chronic Candida Infection Risk

Candida vaginitis is a frequent clinical diagnosis with up to 8% of women experiencing recurrent vulvovaginal candidiasis (RVVC) globally. RVVC is characterized by at least three episodes per year. More...
26 Jun 2019
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