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Microbiology

Image: Methicillin-resistant Staphylococcus aureus (MRSA) growing normally in upper panel and tolerant to an antibiotic in lower panel (Photo courtesy of Nathalie Balaban and Jiafeng Liu).

Resilient Bacteria May Be Treatable with Currently-Available Therapies

 Bacteria develop defenses against hostile elements in their environment. One common tactic is "tolerance," that is, lying dormant during antibiotic treatment. In this way, bacteria evade antibiotic treatment because antibiotics can only spot and kill growing targets. More...
29 Jan 2020
Image: Digitally colorized scanning electron micrograph (SEM) depicts numerous mustard-colored, spheroid shaped, methicillin-resistant, Staphylococcus aureus (MRSA) bacteria, enmeshed within the pseudopodia of a red-colored human neutrophil (Photo courtesy of National Institute of Allergy and Infectious Diseases).

Infectious Disease Consultation Lowers Risk of Bloodstream Infection Mortality

 Among patients with common bloodstream infections, lack of infectious disease consultation was associated with a more than fourfold increased hazard of death at three months. More...
29 Jan 2020
Image: Blood smear of patient with intracellular cocci in pairs inside a white blood cell, possibly indicating sepsis. Oncostatin-M is a biomarker for sepsis risk (Photo courtesy of Dr. Wim van der Meer).

Biomarker Identifies Septic Patients at Higher Risk for Mortality

 Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. More...
28 Jan 2020
Image: Photomicrograph of Rickettsia conorii in Vero cells (red rods; magnification ×1,000) (Photo courtesy of Wikimedia Commons)

Identification of Rickettsial Biomarker Facilitates Early Diagnosis of Tick-borne Spotted Fevers

 A protein biomarker has been identified that enables the rapid and specific early diagnosis of tick-borne rickettsial diseases such as Rocky Mountain spotted fever and Mediterranean spotted fever. More...
27 Jan 2020
Image: Photomicrograph of a sputum specimen showing the presence of numerous Mycobacterium tuberculosis bacteria (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)

Genetic Biomarkers Detect Incipient Tuberculosis, Predict Progression of the Disease

 A panel of genetic biomarkers in samples of whole blood has been confirmed as a useful biomarker for the detection of incipient tuberculosis (TB). More...
27 Jan 2020
Image: Immunostaining of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric biopsy (Photo courtesy of KGH).

Helicobacter pylori Triggers Development of Stomach Disease

 Helicobacter pylori is a paradigm persistent pathogen colonizing about 50% of the human world population and represents a major risk factor for chronic gastritis, peptic ulceration and gastric malignancies. More...
23 Jan 2020
Image: PrimeStore Molecular Transport Medium (MTM) is the first molecular transport device designed to inactivate pathogens and stabilize both RNA and DNA for downstream molecular testing and characterization (Photo courtesy of Longhorn Vaccines and Diagnostics).

Mouth Swab Molecular Test for Tuberculosis Validated

 Clinical investigators are testing an approach being developed to diagnose tuberculosis using mouth swabs, which could become an alternate approach to sample collection methods currently used to do tuberculosis (TB) testing. More...
22 Jan 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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