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Hematology

Image: A histopathology of primary central nervous system lymphoma showing small purple cells along the blood vessel in the brain (Photo courtesy of Columbia University Medical Center).

Biomarkers Analyzed for Central Nervous System Lymphoma

Primary central nervous system lymphoma (PCNSL) is a rare type of extranodal non-Hodgkin lymphoma (NHL) accounting for 3% of all newly diagnosed primary intracranial tumors. In patients presenting with focal brain lesions, fast and reliable diagnosis of PCNSL remains a challenge. More...
29 Oct 2019
Image: Myeloperoxidase positive staining from a patient with acute myeloid leukemia (Photo courtesy of Monika Nema, MD).

Specific Cytokines Are Significant Biomarkers for AML

Acute myeloid leukemia is a hematopoietic neoplasm derived from early progenitor myeloid cells; it is characterized by clonal expansion of myeloblasts, which are immature myeloid progenitors that accumulate in the bone marrow (BM). More...
16 Oct 2019
Image: The NovoCyte flow cytometer (Photo courtesy of ACEA Bio).

Blood Monocyte Functions Altered in Parkinson's Disease

Parkinson's disease is characterized by the slow degeneration of the neurons in brain due to the abnormal accumulation of a protein called alpha-synuclein. This leads to the patients shaking and then to the slow, stiff movements which many people associate with the disease. More...
15 Oct 2019
Image: In acute myeloid leukemia (AML), defective blood cells (stained purple) are present. When the cells have a double mutation of both the IDH2 and SRSF2 genes (bottom right), the number of defective cells rises considerably, indicating a more lethal disease (Photo courtesy of Cold Spring Harbor Laboratory).

Two Different Mutations Identified as Cause of AML

Two very different mutations have been identified as unexpected partners in crime for causing the blood cancer acute myeloid leukemia (AML). Expert analysis helped reveal how this deadly duo is far more common in AML than thought. More...
15 Oct 2019
Image: A specific Parkinson’s gene mutation has been linked to a higher risk of leukemia and colon cancer (Photo courtesy of BioNews Services).

Parkinson’s Gene Mutation Linked to Higher Risk of Leukemia

Parkinson's disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement. More...
10 Oct 2019
Image: The ABX Micros CRP 200 hematology analyzer (Photo courtesy of Horiba Medical).

Human CRP-Levels Compared Using Point-of-Care Methods

Due to the rapid increase of the C-reactive protein (CRP) concentration in the event of an inflammatory disease, CRP is regarded as one of the most important acute phase proteins. More...
08 Oct 2019
Image: The Gen-S hematology analyzer (Photo courtesy of Beckman Coulter).

Hematological Parameters Detect Patients with Acute VTE

Venous thromboembolism (VTE) encompasses deep venous thrombosis (DVT) and pulmonary embolism (PE). VTE causes cardiovascular death and disability and the risk of PE‐associated mortality and morbidity extends far beyond the acute phase of the disease. More...
08 Oct 2019
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.

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