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Clinical Chemistry

Image: The UCap microfiber urine collection pad (Photo courtesy of BioDesign/HUJI).

Microfiber Pad Helps Collect Uncontaminated Urine Samples

A new noninvasive microfiber pad draws urine samples in seconds, preventing cross-contamination during collection.  More...
27 Jan 2016
Image: Soluble Flt-1 (sFlt-1) causes endothelial dysfunction by antagonizing vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) (Photo courtesy of the International Society of Nephrology).

Blood Test Can Rule Out Preeclampsia in Pregnant Women

A clinical study has shown that a new preeclampsia test can better predict which women will, and will not, develop preeclampsia and this could reduce hospitalization by up to 50%, saving healthcare systems excess expenditure.   More...
26 Jan 2016
Image: The Hitachi 911 Chemistry Analyzer (Photo courtesy of Roche Diagnostics).

High Urate Levels May Indicate Parkinson's Risk in Men

Parkinson's disease is a motor system disorder that usually appears in people aged over 60 years and it results from the loss of dopamine-producing brain cells. There is currently no cure, but treatments can be given that replace or mimic the role of dopamine in the brain, providing relief from the symptoms.   More...
26 Jan 2016
Image: Fetal fibronectin is a “glue-like” protein that holds the developing baby in the womb (Photo courtesy of Hologic Inc.).

Biomarker Predicts Risk of Preterm Birth Earlier

A standard biomarker test offered earlier in pregnancy could potentially help doctors to better identify women at risk of giving birth prematurely, thus enabling health services to focus treatments on women at highest risk.  More...
26 Jan 2016
Image: Clinical features of local recurrences that are defined as the reappearance of melanoma in or contiguous with an excision scar or graft and bearing an in situ component (Photo courtesy of Dr. Paola Savoia).

Blood Test Monitors DNA Fragments for Melanoma Metastases

A blood test which monitors blood levels of DNA fragments from dead cancer cells does a superior job than the current standard test at tracking the severity and potential spread of metastatic melanoma.  More...
25 Jan 2016
Image: Differential mobility spectra extracted from the GC-DMS response surface for 1,3-propandiol (D) and GHB (E) (Photo courtesy of Loughborough University).

Saliva Test Detects GHB and Alcohol Poisonings

A saliva-based test has been developed that offers the potential to screen for poisons commonly associated with the cheap or imitation manufacture of alcohol, and γ-hydroxybutyric acid, the so-called “date rape” drug GHB.  More...
19 Jan 2016
Image: Graph of mass-spectrometry-based mapping of tissue-specific protein in blood plasma, from the study of sepsis using quantitative targeted proteomics (Photo courtesy of Malmström laboratory, Lund University).

Protein Patterning: Novel Tool for Studying Sepsis

In a new approach using quantitative targeted proteomics, researchers have for the first time developed a way to use mass-spectrometry to measure hundreds of organ proteins in a single blood sample. The resulting protein patterns can help determine sepsis severity, which organs have been damaged, and may lead to faster diagnostics.  More...
18 Jan 2016
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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